标题
Acquired immunity and Alzheimer's disease
作者
关键词
-
出版物
Journal of Biomedical Research
Volume 37, Issue 1, Pages 15
出版商
Journal of Biomedical Research
发表日期
2022-07-16
DOI
10.7555/jbr.36.20220083
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow
- (2022) Chenglong Xie et al. Nature Biomedical Engineering
- Choroid Plexus Volume and Permeability at Brain MRI within the Alzheimer Disease Clinical Spectrum
- (2022) Jong Duck Choi et al. RADIOLOGY
- Therapeutic B-cell depletion reverses progression of Alzheimer’s disease
- (2021) Ki Kim et al. Nature Communications
- Single-cell RNA sequencing reveals B cell–related molecular biomarkers for Alzheimer’s disease
- (2021) Liu-Lin Xiong et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease
- (2020) David Gate et al. NATURE
- IL-33-PU.1 Transcriptome Reprogramming Drives Functional State Transition and Clearance Activity of Microglia in Alzheimer’s Disease
- (2020) Shun-Fat Lau et al. Cell Reports
- Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease
- (2019) Oliver Preische et al. NATURE MEDICINE
- PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model
- (2019) Neta Rosenzweig et al. Nature Communications
- Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease
- (2019) Evandro F. Fang et al. NATURE NEUROSCIENCE
- Meningeal lymphatic vessels at the skull base drain cerebrospinal fluid
- (2019) Ji Hoon Ahn et al. NATURE
- The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk
- (2019) Yuetiva Deming et al. Science Translational Medicine
- Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
- (2019) Justin M. Long et al. CELL
- Microglial mitophagy mitigates neuroinflammation in Alzheimer's disease
- (2019) Sofie Lautrup et al. NEUROCHEMISTRY INTERNATIONAL
- Blockade of α4 integrins reduces leukocyte–endothelial interactions in cerebral vessels and improves memory in a mouse model of Alzheimer’s disease
- (2019) Enrica Pietronigro et al. Scientific Reports
- Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation
- (2019) Stephen Zewinger et al. NATURE IMMUNOLOGY
- Cerebrospinal fluid γδ T cell frequency is age-related: a case-control study of 435 children with inflammatory and non-inflammatory neurological disorders
- (2018) M. R. Pranzatelli et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Deep cervical lymph node ligation aggravates AD-like pathology of APP/PS1 mice
- (2018) Linmei Wang et al. BRAIN PATHOLOGY
- Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping
- (2018) Giovanni Di Liberto et al. CELL
- Functional aspects of meningeal lymphatics in ageing and Alzheimer’s disease
- (2018) Sandro Da Mesquita et al. NATURE
- CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature
- (2018) Antoine Louveau et al. NATURE NEUROSCIENCE
- Decline in Sirtuin-1 expression and activity plays a critical role in blood-brain barrier permeability in aging
- (2018) Svetlana M. Stamatovic et al. NEUROBIOLOGY OF DISEASE
- Aquaporin-4-dependent glymphatic solute transport in the rodent brain
- (2018) Humberto Mestre et al. eLife
- Alterations in the Peripheral Immune System in Dementia
- (2017) Mandy Busse et al. JOURNAL OF ALZHEIMERS DISEASE
- Late onset Alzheimer’s disease genetics implicates microglial pathways in disease risk
- (2017) Anastasia G. Efthymiou et al. Molecular Neurodegeneration
- Microglia emerge as central players in brain disease
- (2017) Michael W Salter et al. NATURE MEDICINE
- Regulatory T cells promote myelin regeneration in the central nervous system
- (2017) Yvonne Dombrowski et al. NATURE NEUROSCIENCE
- A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease
- (2017) Kuan-lin Huang et al. NATURE NEUROSCIENCE
- Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case–control study
- (2017) Natasha Z. R. Steele et al. PLOS MEDICINE
- Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease
- (2017) Niklas Mattsson et al. JAMA Neurology
- Dramatic Shifts in Circulating CD4 but not CD8 T Cell Subsets in Mild Alzheimer's Disease
- (2017) Anis Larbi et al. JOURNAL OF ALZHEIMERS DISEASE
- Interleukin-2 improves amyloid pathology, synaptic failure and memory in Alzheimer’s disease mice
- (2016) Sandro Alves et al. BRAIN
- Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy
- (2016) Cyril Laurent et al. BRAIN
- Regulatory T cells delay disease progression in Alzheimer-like pathology
- (2016) Cira Dansokho et al. BRAIN
- Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease
- (2016) Claudio Villegas-Llerena et al. CURRENT OPINION IN NEUROBIOLOGY
- Intracerebral transplantation of interleukin 13-producing mesenchymal stem cells limits microgliosis, oligodendrocyte loss and demyelination in the cuprizone mouse model
- (2016) Debbie Le Blon et al. Journal of Neuroinflammation
- Genetic variations underlying Alzheimer's disease: evidence from genome-wide association studies and beyond
- (2016) Elise Cuyvers et al. LANCET NEUROLOGY
- Alzheimer’s Disease Variants with the Genome-Wide Significance are Significantly Enriched in Immune Pathways and Active in Immune Cells
- (2016) Qinghua Jiang et al. MOLECULAR NEUROBIOLOGY
- Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid
- (2016) Christian Schläger et al. NATURE
- PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease
- (2016) Kuti Baruch et al. NATURE MEDICINE
- Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease
- (2016) Weiguo Peng et al. NEUROBIOLOGY OF DISEASE
- TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy
- (2016) Peng Yuan et al. NEURON
- The adaptive immune system restrains Alzheimer’s disease pathogenesis by modulating microglial function
- (2016) Samuel E. Marsh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Astrogliosis: An integral player in the pathogenesis of Alzheimer's disease
- (2016) Lana M. Osborn et al. PROGRESS IN NEUROBIOLOGY
- Complement and microglia mediate early synapse loss in Alzheimer mouse models
- (2016) S. Hong et al. SCIENCE
- How neuroinflammation contributes to neurodegeneration
- (2016) R. M. Ransohoff SCIENCE
- Early changes in CSF sTREM2 in dominantly inherited Alzheimers disease occur after amyloid deposition and neuronal injury
- (2016) M. Suarez-Calvet et al. Science Translational Medicine
- Immunosuppressive and Prometastatic Functions of Myeloid-Derived Suppressive Cells Rely upon Education from Tumor-Associated B Cells
- (2015) M. Bodogai et al. CANCER RESEARCH
- Regulatory B Cells: Origin, Phenotype, and Function
- (2015) Elizabeth C. Rosser et al. IMMUNITY
- A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules
- (2015) Aleksanteri Aspelund et al. JOURNAL OF EXPERIMENTAL MEDICINE
- T Cells—Protective or Pathogenic in Alzheimer’s Disease?
- (2015) Róisín M. McManus et al. Journal of Neuroimmune Pharmacology
- Soluble amyloid triggers a myeloid differentiation factor 88 and interferon regulatory factor 7 dependent neuronal type-1 interferon response in vitro
- (2015) Myles Robert Minter et al. Journal of Neuroinflammation
- Amyloid Oligomers Disrupt Blood-CSF Barrier Integrity by Activating Matrix Metalloproteinases
- (2015) M. Brkic et al. JOURNAL OF NEUROSCIENCE
- Microglia-Dependent Alteration of Glutamatergic Synaptic Transmission and Plasticity in the Hippocampus during Peripheral Inflammation
- (2015) K. Riazi et al. JOURNAL OF NEUROSCIENCE
- Neuroinflammation in Alzheimer's disease
- (2015) Michael T Heneka et al. LANCET NEUROLOGY
- Deletion of aquaporin-4 in APP/PS1 mice exacerbates brain Aβ accumulation and memory deficits
- (2015) Zhiqiang Xu et al. Molecular Neurodegeneration
- Structural and functional features of central nervous system lymphatic vessels
- (2015) Antoine Louveau et al. NATURE
- Clearance systems in the brain—implications for Alzheimer disease
- (2015) Jenna M. Tarasoff-Conway et al. Nature Reviews Neurology
- Immune attack: the role of inflammation in Alzheimer disease
- (2015) Frank L. Heppner et al. NATURE REVIEWS NEUROSCIENCE
- Amyloid fibrils activate B-1a lymphocytes to ameliorate inflammatory brain disease
- (2015) Michael Phillip Kurnellas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microglial Malfunction: The Third Rail in the Development of Alzheimer's Disease
- (2015) Siddhita D. Mhatre et al. TRENDS IN NEUROSCIENCES
- Focal MMP-2 and MMP-9 Activity at the Blood-Brain Barrier Promotes Chemokine-Induced Leukocyte Migration
- (2015) Jian Song et al. Cell Reports
- Cerebral regulatory T cells restrain microglia/macrophage-mediated inflammatory responses via IL-10
- (2014) Luokun Xie et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Neuroprotective Immunity: T Cell-Derived Glutamate Endows Astrocytes with a Neuroprotective Phenotype
- (2014) S. K. Garg et al. JOURNAL OF IMMUNOLOGY
- B Lymphocytes Promote Expansion of Regulatory T Cells in Oral Tolerance: Powerful Induction by Antigen Coupled to Cholera Toxin B Subunit
- (2014) J.-B. Sun et al. JOURNAL OF IMMUNOLOGY
- IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases
- (2014) Ping Shen et al. NATURE
- Double function at the blood–brain barrier
- (2014) Christer Betsholtz NATURE
- Microglial priming in neurodegenerative disease
- (2014) V. Hugh Perry et al. Nature Reviews Neurology
- Occludin deficiency with BACE1 elevation in cerebral amyloid angiopathy
- (2014) X. Cheng et al. NEUROLOGY
- Microglial CR3 Activation Triggers Long-Term Synaptic Depression in the Hippocampus via NADPH Oxidase
- (2014) Jingfei Zhang et al. NEURON
- Astrocytes Modulate the Polarization of CD4+ T Cells to Th1 Cells
- (2014) Eléonore Beurel et al. PLoS One
- New roles for Fc receptors in neurodegeneration-the impact on Immunotherapy for Alzheimer's Disease
- (2014) James P. Fuller et al. Frontiers in Neuroscience
- Early BCR Events and Antigen Capture, Processing, and Loading on MHC Class II on B Cells
- (2014) Ana M. Avalos et al. Frontiers in Immunology
- Characteristics of differentiated CD8+ and CD4+ T cells present in the human brain
- (2013) Joost Smolders et al. ACTA NEUROPATHOLOGICA
- Anti-amyloid β autoantibodies in cerebral amyloid angiopathy-related inflammation: Implications for amyloid-modifying therapies
- (2013) Fabrizio Piazza et al. ANNALS OF NEUROLOGY
- B Cells Promote Induction of Experimental Autoimmune Encephalomyelitis by Facilitating Reactivation of T Cells in the Central Nervous System
- (2013) E. R. Pierson et al. JOURNAL OF IMMUNOLOGY
- IFN- Production by Amyloid -Specific Th1 Cells Promotes Microglial Activation and Increases Plaque Burden in a Mouse Model of Alzheimer's Disease
- (2013) T. C. Browne et al. JOURNAL OF IMMUNOLOGY
- Th1 Polarization of T Cells Injected into the Cerebrospinal Fluid Induces Brain Immunosurveillance
- (2013) Y. Fisher et al. JOURNAL OF IMMUNOLOGY
- Transcranial amelioration of inflammation and cell death after brain injury
- (2013) Theodore L. Roth et al. NATURE
- CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology
- (2013) Elizabeth M Bradshaw et al. NATURE NEUROSCIENCE
- Enhanced Chemokine Receptor Expression on Leukocytes of Patients with Alzheimer's Disease
- (2013) David Goldeck et al. PLoS One
- Increased Levels of Antigen-Bound β-Amyloid Autoantibodies in Serum and Cerebrospinal Fluid of Alzheimer’s Disease Patients
- (2013) Madalina Maftei et al. PLoS One
- Th17 Cell-Mediated Neuroinflammation Is Involved in Neurodegeneration of Aβ1-42-Induced Alzheimer’s Disease Model Rats
- (2013) Jun Zhang et al. PLoS One
- Amyloid-β Immunotherapy for Alzheimers Disease
- (2012) H.J. Fu et al. CNS & Neurological Disorders-Drug Targets
- Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study
- (2012) David H Cribbs et al. Journal of Neuroinflammation
- Genetic insights in Alzheimer's disease
- (2012) Karolien Bettens et al. LANCET NEUROLOGY
- IgA NMDA receptor antibodies are markers of synaptic immunity in slow cognitive impairment
- (2012) H. Pruss et al. NEUROLOGY
- A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid
- (2012) J. J. Iliff et al. Science Translational Medicine
- Aging-associated B7-DC+B cells enhance anti-tumor immunity via Th1 and Th17 induction
- (2011) Kei Tomihara et al. AGING CELL
- Amyloid Beta Induces Oxidative Stress-Mediated Blood–Brain Barrier Changes in Capillary Amyloid Angiopathy
- (2011) Anna Carrano et al. ANTIOXIDANTS & REDOX SIGNALING
- Alzheimer's disease, autoimmunity and inflammation. The good, the bad and the ugly
- (2011) F. Sardi et al. AUTOIMMUNITY REVIEWS
- Tumor-Evoked Regulatory B Cells Promote Breast Cancer Metastasis by Converting Resting CD4+ T Cells to T-Regulatory Cells
- (2011) P. B. Olkhanud et al. CANCER RESEARCH
- DNA Immunization Against Amyloid beta 42 has High Potential as Safe Therapy for Alzheimer’s Disease as it Diminishes Antigen-Specific Th1 and Th17 Cell Proliferation
- (2011) Doris Lambracht-Washington et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Immune profiling of Alzheimer patients
- (2011) Mariavaleria Pellicanò et al. JOURNAL OF NEUROIMMUNOLOGY
- A potential role for the PD1/PD-L1 pathway in the neuroinflammation of Alzheimer's disease
- (2011) Marina Saresella et al. NEUROBIOLOGY OF AGING
- B cells and immunosenescence: A focus on IgG+IgD−CD27− (DN) B cells in aged humans
- (2010) Matteo Bulati et al. AGEING RESEARCH REVIEWS
- B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity
- (2010) Martin S. Weber et al. ANNALS OF NEUROLOGY
- Improvement in disability after alemtuzumab treatment of multiple sclerosis is associated with neuroprotective autoimmunity
- (2010) Joanne L. Jones et al. BRAIN
- Activation of mixed glia by Aβ-specific Th1 and Th17 cells and its regulation by Th2 cells
- (2010) K. McQuillan et al. BRAIN BEHAVIOR AND IMMUNITY
- TGF-β1 affects endothelial cell interaction with macrophages and T cells leading to the development of cerebrovascular amyloidosis
- (2010) Ronen Weiss et al. BRAIN BEHAVIOR AND IMMUNITY
- Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease
- (2010) Taye H Hamza et al. NATURE GENETICS
- IL-35-mediated induction of a potent regulatory T cell population
- (2010) Lauren W Collison et al. NATURE IMMUNOLOGY
- Signal Regulatory Protein-β1
- (2009) Sadanand Gaikwad et al. AMERICAN JOURNAL OF PATHOLOGY
- Differential immune cell dynamics in the CNS cause CD4+ T cell compartmentalization
- (2009) Volker Siffrin et al. BRAIN
- Functional interleukin-17 receptor A is expressed in central nervous system glia and upregulated in experimental autoimmune encephalomyelitis
- (2009) Jayasri Sarma et al. Journal of Neuroinflammation
- T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes
- (2009) Greta Guarda et al. NATURE
- C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE
- (2009) Andrea Reboldi et al. NATURE IMMUNOLOGY
- Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis
- (2009) Gurumoorthy Krishnamoorthy et al. NATURE MEDICINE
- Aβ-specific Th2 cells provide cognitive and pathological benefits to Alzheimer's mice without infiltrating the CNS
- (2009) Chuanhai Cao et al. NEUROBIOLOGY OF DISEASE
- Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression
- (2008) Takashi Matsushita et al. JOURNAL OF CLINICAL INVESTIGATION
- Aβ accumulation in choroid plexus is associated with mitochondrial-induced apoptosis
- (2008) Teo Vargas et al. NEUROBIOLOGY OF AGING
- Peripheral T cells derived from Alzheimer's disease patients overexpress CXCR2 contributing to its transendothelial migration, which is microglial TNF-α-dependent
- (2008) Yi-Jun Liu et al. NEUROBIOLOGY OF AGING
- Systemic immune aberrations in Alzheimer's disease patients
- (2007) Konstantinos Bonotis et al. JOURNAL OF NEUROIMMUNOLOGY
- CD40L disruption enhances Aβ vaccine-mediated reduction of cerebral amyloidosis while minimizing cerebral amyloid angiopathy and inflammation
- (2007) D. Obregon et al. NEUROBIOLOGY OF DISEASE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started