Chlorogenic Acid‐Conjugated Nanoparticles Suppression of Platelet Activation and Disruption to Tumor Vascular Barriers for Enhancing Drug Penetration in Tumor

A novel oncotherapy strategy, direct thrombin inhibitors suppress progression, dissemination and spontaneous metastasis in non‐small cell lung cancer

(2021) Bing Zhao et al.   BRITISH JOURNAL OF PHARMACOLOGY

A near-infrared light-responsive extracellular vesicle as a “Trojan horse” for tumor deep penetration and imaging-guided therapy

(2021) Zeng Xu et al.   BIOMATERIALS

In-situ intramolecular synthesis of tubular carbon nitride S-scheme homojunctions with exceptional in-plane exciton splitting and mechanism insight

(2021) Yongchao Ma et al.   CHEMICAL ENGINEERING JOURNAL

Pharmacokinetics, Biodistribution, and Biosafety of PEGylated Gold Nanoparticles In Vivo

(2021) Katarina Kozics et al.   Nanomaterials

Chlorogenic acid: Potential source of natural drugs for the therapeutics of fibrosis and cancer

(2021) Ebuka-Olisaemeka Nwafor et al.   Translational Oncology

A Size‐Changeable Collagenase‐Modified Nanoscavenger for Increasing Penetration and Retention of Nanomedicine in Deep Tumor Tissue

(2020) Funeng Xu et al.   ADVANCED MATERIALS

Antibacterial activity of chlorogenic acid-loaded SiO2 nanoparticles caused by accumulation of reactive oxygen species

(2020) Zekun Wang et al.   NANOTECHNOLOGY

Chlorogenic acids in cardiovascular disease: A review of pharmacology and pharmacokinetics

(2020) Lin Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Spatially separating redox centers on 2D carbon nitride with cobalt single atom for photocatalytic H2O2production

(2020) Chiheng Chu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chlorogenic acid: A comprehensive review of the dietary sources, processing effects, bioavailability, beneficial properties, mechanisms of action, and future directions

(2020) Huijie Lu et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Synergistic breast cancer suppression efficacy of doxorubicin by combination with glycyrrhetinic acid as an angiogenesis inhibitor

(2020) Jinfeng Shi et al.   PHYTOMEDICINE

‘Adhesion and release’ nanoparticle-mediated efficient inhibition of platelet activation disrupts endothelial barriers for enhanced drug delivery in tumors

(2020) Jinxu Cao et al.   BIOMATERIALS

Thrombin Generation and Cancer: Contributors and Consequences

(2019) Caroline Reddel et al.   Cancers

Perfluorocarbon nanoparticle-mediated platelet inhibition promotes intratumoral infiltration of T cells and boosts immunotherapy

(2019) Zaigang Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protective effect of morin on doxorubicin-induced hepatorenal toxicity in rats

(2019) Müslüm Kuzu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Chlorogenic acid intercalated Gadolinium–Zinc/Aluminium layered double hydroxide and gold nanohybrid for MR imaging and drug delivery

(2019) Muhammad Sani Usman et al.   MATERIALS CHEMISTRY AND PHYSICS

Natural History of Tumor Thrombus: A Single-Centre Retrospective Study

(2019) Curtis Marcoux et al.   BLOOD

Cytotoxicity of doxorubicin conjugated with C60 fullerene. Structural and in vitro studies

(2019) Kamila Butowska et al.   STRUCTURAL CHEMISTRY

In-situ synthesis of direct solid-state dual Z-scheme WO 3 /g-C 3 N 4 /Bi 2 O 3 photocatalyst for the degradation of refractory pollutant

(2018) Longbo Jiang et al.   APPLIED CATALYSIS B-ENVIRONMENTAL

The Platelet Lifeline to Cancer: Challenges and Opportunities

(2018) Monika Haemmerle et al.   CANCER CELL

Chlorogenic acid prevents diabetic nephropathy by inhibiting oxidative stress and inflammation through modulation of the Nrf2/HO-1 and NF-ĸB pathways

(2018) Liping Bao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Chlorogenic acid attenuates diabetic retinopathy by reducing VEGF expression and inhibiting VEGF-mediated retinal neoangiogenesis

(2018) Xiyu Mei et al.   VASCULAR PHARMACOLOGY

Role of platelets and platelet receptors in cancer metastasis

(2018) Martin Schlesinger   Journal of Hematology & Oncology

Tumor Microenvironment-Responsive Ultrasmall Nanodrug Generators with Enhanced Tumor Delivery and Penetration

(2018) Pengfei Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Perfluorocarbon Nanoparticles Mediated Platelet Blocking Disrupt Vascular Barriers to Improve the Efficacy of Oxygen-Sensitive Antitumor Drugs

(2018) Zaigang Zhou et al.   Small

Enhancing the Accumulation of Polymer Micelles by Selectively Dilating Tumor Blood Vessels with NO for Highly Effective Cancer Treatment

(2018) Guoqing Wei et al.   Advanced Healthcare Materials

Predictors of bile tree pathology in patients presenting with gallbladder disease

(2017) Mahmoud A. Rahal et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

The effect of particle shape on cellular interaction and drug delivery applications of micro- and nanoparticles

(2017) Anil B. Jindal   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Chlorogenic acid inhibits hepatocellular carcinoma in vitro and in vivo

(2017) Yuan Yan et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Carboxyl-rich g-C 3 N 4 nanoparticles: Synthesis, characterization and their application for selective fluorescence sensing of Hg 2+ and Fe 3+ in aqueous media

(2017) Ghasem Shiravand et al.   SENSORS AND ACTUATORS B-CHEMICAL

Multistage Targeting Strategy Using Magnetic Composite Nanoparticles for Synergism of Photothermal Therapy and Chemotherapy

(2017) Yi Wang et al.   Small

Structural, morphological, ferromagnetic and photoluminescence properties of Fe-doped ZnO, prepared by hydrothermal route

(2017) Marin Cernea et al.   SUPERLATTICES AND MICROSTRUCTURES

Molecular Bases Underlying the Hepatoprotective Effects of Coffee

(2017) Federico Salomone et al.   Nutrients

Nanoparticle-mediated local depletion of tumour-associated platelets disrupts vascular barriers and augments drug accumulation in tumours

(2017) Suping Li et al.   Nature Biomedical Engineering

Albumin-Mediated Biomineralization of Paramagnetic NIR Ag2S QDs for Tiny Tumor Bimodal Targeted Imaging in Vivo

(2016) Jing Zhang et al.   ACS Applied Materials & Interfaces

MnO2Gatekeeper: An Intelligent and O2-Evolving Shell for Preventing Premature Release of High Cargo Payload Core, Overcoming Tumor Hypoxia, and Acidic H2O2-Sensitive MRI

(2016) Zhifang Ma et al.   ADVANCED FUNCTIONAL MATERIALS

Thrombin—unique coagulation system protein with multifaceted impacts on cancer and metastasis

(2016) Marek Z. Wojtukiewicz et al.   CANCER AND METASTASIS REVIEWS

Chlorogenic acid protects against liver fibrosis in vivo and in vitro through inhibition of oxidative stress

(2016) Haitao Shi et al.   CLINICAL NUTRITION

Chlorogenic acid suppresses monocrotaline-induced sinusoidal obstruction syndrome: The potential contribution of NFκB, Egr1, Nrf2, MAPKs and PI3K signals

(2016) Zhiyong Zheng et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Chlorogenic Acid Attenuates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting TLR4/NF-κB Signal Pathway

(2016) Han-Yang Ye et al.   INFLAMMATION

Investigation of the anticoagulant and antithrombotic effects of chlorogenic acid

(2016) Jun-Hui Choi et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Chlorogenic acid improves ex vivo vessel function and protects endothelial cells against HOCl-induced oxidative damage, via increased production of nitric oxide and induction of Hmox-1

(2016) Rujia Jiang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Nanomedicine strategies to overcome the pathophysiological barriers of pancreatic cancer

(2016) Pavan P. Adiseshaiah et al.   Nature Reviews Clinical Oncology

The multifunctionality of berries toward blood platelets and the role of berry phenolics in cardiovascular disorders

(2016) Beata Olas   PLATELETS

FeIII-Doped Two-Dimensional C3N4Nanofusiform: A New O2-Evolving and Mitochondria-Targeting Photodynamic Agent for MRI and Enhanced Antitumor Therapy

(2016) Zhifang Ma et al.   Small

Role of platelets in cancer and cancer-associated thrombosis: Experimental and clinical evidences

(2016) Soraya Mezouar et al.   THROMBOSIS RESEARCH

Co-delivery of doxorubicin and curcumin by pH-sensitive prodrug nanoparticle for combination therapy of cancer

(2016) Yumin Zhang et al.   Scientific Reports

Chlorogenic acid enhances the effects of 5-fluorouracil in human hepatocellular carcinoma cells through the inhibition of extracellular signal-regulated kinases

(2015) Yuan Yan et al.   ANTI-CANCER DRUGS

Lung cancer chemotherapy agents increase procoagulant activity via protein disulfide isomerase-dependent tissue factor decryption

(2015) Zakhar Lysov et al.   BLOOD COAGULATION & FIBRINOLYSIS

Protease-activated receptors (PARs)—biology and role in cancer invasion and metastasis

(2015) Marek Z. Wojtukiewicz et al.   CANCER AND METASTASIS REVIEWS

Mitochondria-Derived Reactive Oxygen Species Play an Important Role in Doxorubicin-Induced Platelet Apoptosis

(2015) Zhicheng Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

In vitro cytotoxicity analysis of doxorubicin-loaded/superparamagnetic iron oxide colloidal nanoassemblies on MCF7 and NIH3T3 cell lines

(2015) Katerina Tomankova et al.   International Journal of Nanomedicine

H2O2-Activatable and O2-Evolving Nanoparticles for Highly Efficient and Selective Photodynamic Therapy against Hypoxic Tumor Cells

(2015) Huachao Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Polymer-Based Prodrugs: Improving Tumor Targeting and the Solubility of Small Molecule Drugs in Cancer Therapy

(2015) Sonja Dragojevic et al.   MOLECULES

Chlorogenic acid loaded chitosan nanoparticles with sustained release property, retained antioxidant activity and enhanced bioavailability

(2015) Ilaiyaraja Nallamuthu et al.   Asian Journal of Pharmaceutical Sciences

Platelets and cancer: a casual or causal relationship: revisited

(2014) David G. Menter et al.   CANCER AND METASTASIS REVIEWS

Comparative Cytotoxicity of Artemisinin and Cisplatin and Their Interactions with Chlorogenic Acids in MCF7 Breast Cancer Cells

(2014) John O. Suberu et al.   ChemMedChem

Chlorogenic Acid Inhibits Human Platelet Activation and Thrombus Formation

(2014) Eduardo Fuentes et al.   PLoS One

Polyacrylamide-Based Biocompatible Nanoplatform Enhances the Tumor Uptake, PET/fluorescence Imaging and Anticancer Activity of a Chlorophyll Analog

(2014) Anurag Gupta et al.   Theranostics

Facile one step method realizing scalable production of g-C3N4 nanosheets and study of their photocatalytic H2 evolution activity

(2014) Xiuli Lu et al.   Journal of Materials Chemistry A

Activation of blood coagulation in cancer: implications for tumour progression

(2013) Luize G. Lima et al.   BIOSCIENCE REPORTS

Challenges and Key Considerations of the Enhanced Permeability and Retention Effect for Nanomedicine Drug Delivery in Oncology

(2013) U. Prabhakar et al.   CANCER RESEARCH

Strategies for advancing cancer nanomedicine

(2013) Vikash P. Chauhan et al.   NATURE MATERIALS

Tumor-platelet interaction in solid tumors

(2012) Daniel Buergy et al.   INTERNATIONAL JOURNAL OF CANCER

RGD-modified PEG–PAMAM–DOX conjugates: In vitro and in vivo studies for glioma

(2011) Lihong Zhang et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

How platelets safeguard vascular integrity

(2011) B. HO-TIN-NOÉ et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Supramolecular Stacking of Doxorubicin on Carbon Nanotubes for In Vivo Cancer Therapy

(2009) Zhuang Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Size and shape effects in the biodistribution of intravascularly injected particles

(2009) P. Decuzzi et al.   JOURNAL OF CONTROLLED RELEASE

Modulation of P-glycoprotein ATPase activity by some phytoconstituents

(2009) I. A. Najar et al.   PHYTOTHERAPY RESEARCH

Effect of coffee drinking on platelets: inhibition of aggregation and phenols incorporation

(2008) F. Natella et al.   BRITISH JOURNAL OF NUTRITION

Platelet Granule Secretion Continuously Prevents Intratumor Hemorrhage

(2008) B. Ho-Tin-Noe et al.   CANCER RESEARCH