Activation of blood coagulation in cancer: implications for tumour progression

The Emerging Role of the Thrombin Receptor (PAR-1) in Melanoma Metastasis - a Possible Therapeutic Target

(2015) Gabriel J. Villares et al.   Oncotarget

Microvesicles as risk markers for venous thrombosis

(2013) Pierre-Emmanuel Rautou et al.   Expert Review of Hematology

Lufaxin, a Novel Factor Xa Inhibitor From the Salivary Gland of the Sand Fly Lutzomyia longipalpis Blocks Protease-Activated Receptor 2 Activation and Inhibits Inflammation and Thrombosis In Vivo

(2012) Nicolas Collin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Protease-activated receptor-2 (PAR2) mediates VEGF production through the ERK1/2 pathway in human glioblastoma cell lines

(2012) Angélica Dutra-Oliveira et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer

(2012) J.-G. Wang et al.   BLOOD

Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice

(2012) A. M. Gil-Bernabe et al.   BLOOD

The tick-derived inhibitor Ixolaris prevents tissue factor signaling on tumor cells

(2012) T. C. CARNEIRO-LOBO et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis

(2012) M. Demers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of tissue factor by ixolaris reduces primary tumor growth and experimental metastasis in a murine model of melanoma

(2012) Andreia Da Silva de Oliveira et al.   THROMBOSIS RESEARCH

Hemostatic factors, innate immunity and malignancy

(2012) Jay L. Degen et al.   THROMBOSIS RESEARCH

The relationship between tissue factor and cancer progression: insights from bench and bedside

(2011) Y. W. van den Berg et al.   BLOOD

Carcinoma mucins trigger reciprocal activation of platelets and neutrophils in a murine model of Trousseau syndrome

(2011) B. Shao et al.   BLOOD

Increased expression of protease-activated receptor 1 (PAR-1) in human leukemias

(2011) Camilla de S.B. Veiga et al.   BLOOD CELLS MOLECULES AND DISEASES

Tissue factor and cell signalling in cancer progression and thrombosis

(2011) W. RUF et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Galectin-3 Facilitates Cell Motility in Gastric Cancer by Up-Regulating Protease-Activated Receptor-1(PAR-1) and Matrix Metalloproteinase-1(MMP-1)

(2011) Seok-Jun Kim et al.   PLoS One

Microvesicles as mediators of intercellular communication in cancer—the emerging science of cellular ‘debris’

(2011) Tae Hoon Lee et al.   Seminars in Immunopathology

Malignant transformation in melanocytes is associated with increased production of procoagulant microvesicles

(2011) Luize Lima et al.   THROMBOSIS AND HAEMOSTASIS

Tissue factor over-expression by human pancreatic cancer cells BXPC3 is related to higher prothrombotic potential as compared to breast cancer cells MCF7

(2011) Grigoris T. Gerotziafas et al.   THROMBOSIS RESEARCH

Cooperation of tissue factor cytoplasmic domain and PAR2 signaling in breast cancer development

(2010) F. Schaffner et al.   BLOOD

MicroRNA-19 (miR-19) Regulates Tissue Factor Expression in Breast Cancer Cells

(2010) Xiaoxi Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bleeding complications associated with anticoagulant therapy in patients with cancer

(2010) Javier Trujillo-Santos et al.   THROMBOSIS RESEARCH

Tissue factor in tumour progression

(2009) Janusz Rak et al.   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

Microparticles, thrombosis and cancer

(2009) Anat Aharon et al.   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

Tumor-derived microvesicles modulate the establishment of metastatic melanoma in a phosphatidylserine-dependent manner

(2009) Luize G. Lima et al.   CANCER LETTERS

Tumor-Derived Tissue Factor-Bearing Microparticles Are Associated With Venous Thromboembolic Events in Malignancy

(2009) J. I. Zwicker et al.   CLINICAL CANCER RESEARCH

Cancer cell–derived microparticles bearing P-selectin glycoprotein ligand 1 accelerate thrombus formation in vivo

(2009) Grace M. Thomas et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ixolaris, a tissue factor inhibitor, blocks primary tumor growth and angiogenesis in a glioblastoma model

(2009) T. C. CARNEIRO-LOBO et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Simultaneous tissue factor expression and phosphatidylserine exposure account for the highly procoagulant pattern of melanoma cell lines

(2009) Clarice Kirszberg et al.   MELANOMA RESEARCH

Proteinase-activated receptor 2 expression in breast cancer and its role in breast cancer cell migration

(2009) S Su et al.   ONCOGENE

Tissue factor procoagulant activity of plasma microparticles in patients with cancer-associated disseminated intravascular coagulation

(2008) Florian Langer et al.   ANNALS OF HEMATOLOGY

Protease-Activated Receptor (PAR) 2, but not PAR1, Signaling Promotes the Development of Mammary Adenocarcinoma in Polyoma Middle T Mice

(2008) H. H. Versteeg et al.   CANCER RESEARCH

Tissue Factor Regulation by Epidermal Growth Factor Receptor and Epithelial-to-Mesenchymal Transitions: Effect on Tumor Initiation and Angiogenesis

(2008) C. C. Milsom et al.   CANCER RESEARCH

rNAPc2 Inhibits Colorectal Cancer in Mice through Tissue Factor

(2008) J. Zhao et al.   CLINICAL CANCER RESEARCH

Tissue factor-bearing microparticles derived from tumor cells: impact on coagulation activation

(2008) M. DAVILA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Factor XIII transglutaminase supports hematogenous tumor cell metastasis through a mechanism dependent on natural killer cell function

(2008) J. S. PALUMBO et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Tissue Factor and Protease-Activated Receptor Signaling in Cancer

(2008) Florence Schaffner et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS