A Size‐Changeable Collagenase‐Modified Nanoscavenger for Increasing Penetration and Retention of Nanomedicine in Deep Tumor Tissue

Precisely Striking Tumors without Adjacent Normal Tissue Damage via Mitochondria-Templated Accumulation

(2018) Zhaoyu Ma et al.   ACS Nano

Size-Modulable Nanoprobe for High-Performance Ultrasound Imaging and Drug Delivery against Cancer

(2018) Lu Zhang et al.   ACS Nano

Light-Triggered Retention and Cascaded Therapy of Albumin-Based Theranostic Nanomedicines to Alleviate Tumor Adaptive Treatment Tolerance

(2018) Jing Chen et al.   ADVANCED FUNCTIONAL MATERIALS

Semiconducting Polymer Nanoenzymes with Photothermic Activity for Enhanced Cancer Therapy

(2018) Jingchao Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hemoglobin as a Smart pH-Sensitive Nanocarrier To Achieve Aggregation Enhanced Tumor Retention

(2018) Huan Li et al.   BIOMACROMOLECULES

One-pot synthesis of pH-responsive charge-switchable PEGylated nanoscale coordination polymers for improved cancer therapy

(2018) Yu Yang et al.   BIOMATERIALS

Enzyme-triggered size shrink and laser-enhanced NO release nanoparticles for deep tumor penetration and combination therapy

(2018) Chuan Hu et al.   BIOMATERIALS

Size shrinkable drug delivery nanosystems and priming the tumor microenvironment for deep intratumoral penetration of nanoparticles

(2018) Yimin Niu et al.   JOURNAL OF CONTROLLED RELEASE

Effective treatment of the primary tumor and lymph node metastasis by polymeric micelles with variable particle sizes

(2018) Ling Mei et al.   JOURNAL OF CONTROLLED RELEASE

Optimization of Weight Ratio for DSPE-PEG/TPGS Hybrid Micelles to Improve Drug Retention and Tumor Penetration

(2018) Ya Jin et al.   PHARMACEUTICAL RESEARCH

Supramolecular cisplatin-vorinostat nanodrug for overcoming drug resistance in cancer synergistic therapy

(2017) Shuting Xu et al.   JOURNAL OF CONTROLLED RELEASE

Tumor Microenvironment-Responsive Multistaged Nanoplatform for Systemic RNAi and Cancer Therapy

(2017) Xiaoding Xu et al.   NANO LETTERS

Multicellular tumor spheroids: a relevant 3D model for the in vitro preclinical investigation of polymer nanomedicines

(2017) Gianpiero Lazzari et al.   Polymer Chemistry

Multistage Targeting Strategy Using Magnetic Composite Nanoparticles for Synergism of Photothermal Therapy and Chemotherapy

(2017) Yi Wang et al.   Small

Rethinking cancer nanotheranostics

(2017) Hongmin Chen et al.   Nature Reviews Materials

Tumor-Specific Multiple Stimuli-Activated Dendrimeric Nanoassemblies with Metabolic Blockade Surmount Chemotherapy Resistance

(2016) Yachao Li et al.   ACS Nano

Smart Superstructures with Ultrahigh pH-Sensitivity for Targeting Acidic Tumor Microenvironment: Instantaneous Size Switching and Improved Tumor Penetration

(2016) Hong-Jun Li et al.   ACS Nano

Codelivery of a π-π Stacked Dual Anticancer Drug Combination with Nanocarriers for Overcoming Multidrug Resistance and Tumor Metastasis

(2016) Xiao Wei et al.   ADVANCED FUNCTIONAL MATERIALS

Functionalized, Long-Circulating, and Ultrasmall Gold Nanocarriers for Overcoming the Barriers of Low Nanoparticle Delivery Efficiency and Poor Tumor Penetration

(2016) Kate Y. J. Lee et al.   BIOCONJUGATE CHEMISTRY

Tumor stroma-containing 3D spheroid arrays: A tool to study nanoparticle penetration

(2016) Dwi L. Priwitaningrum et al.   JOURNAL OF CONTROLLED RELEASE

Hyaluronidase Embedded in Nanocarrier PEG Shell for Enhanced Tumor Penetration and Highly Efficient Antitumor Efficacy

(2016) Hao Zhou et al.   NANO LETTERS

Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy

(2016) Hong-Jun Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

pH-Sensitive Polymeric Nanoparticles Modulate Autophagic Effect via Lysosome Impairment

(2016) Yao-Xin Lin et al.   Small

Breaching the Hyaluronan Barrier with PH20-Fc Facilitates Intratumoral Permeation and Enhances Antitumor Efficiency: A Comparative Investigation of Typical Therapeutic Agents in Different Nanoscales

(2016) Shan Liu et al.   Advanced Healthcare Materials

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Hybrid Collagenase Nanocapsules for Enhanced Nanocarrier Penetration in Tumoral Tissues

(2015) María Rocío Villegas et al.   ACS Applied Materials & Interfaces

A Bio-Inspired Rod-Shaped Nanoplatform for Strongly Infecting Tumor Cells and Enhancing the Delivery Efficiency of Anticancer Drugs

(2015) Dan Li et al.   ADVANCED FUNCTIONAL MATERIALS

Dual-Stage-Light-Guided Tumor Inhibition by Mitochondria-Targeted Photodynamic Therapy

(2015) Kai Han et al.   ADVANCED FUNCTIONAL MATERIALS

Stromal barriers and strategies for the delivery of nanomedicine to desmoplastic tumors

(2015) Lei Miao et al.   JOURNAL OF CONTROLLED RELEASE

Bromelain Surface Modification Increases the Diffusion of Silica Nanoparticles in the Tumor Extracellular Matrix

(2014) Alessandro Parodi et al.   ACS Nano

Self-Regulated Multifunctional Collaboration of Targeted Nanocarriers for Enhanced Tumor Therapy

(2014) Hongjun Gao et al.   BIOMACROMOLECULES

Delivery of platinum(IV) drug to subcutaneous tumor and lung metastasis using bradykinin-potentiating peptide-decorated chitosan nanoparticles

(2014) Xin Wang et al.   BIOMATERIALS

Nanoparticles Functionalized with Collagenase Exhibit Improved Tumor Accumulation in a Murine Xenograft Model

(2014) Surya Murty et al.   PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION

Detouring of cisplatin to access mitochondrial genome for overcoming resistance

(2014) S. Marrache et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multifaceted Transport Characteristics of Nanomedicine: Needs for Characterization in Dynamic Environment

(2013) Altug Ozcelikkale et al.   MOLECULAR PHARMACEUTICS

Multifunctional Albumin Nanoparticles As Combination Drug Carriers for Intra-Tumoral Chemotherapy

(2013) Mingjie Cui et al.   Advanced Healthcare Materials