LncRNA HOXA11-AS promotes glioma malignant phenotypes and reduces its sensitivity to ROS via Tpl2-MEK1/2-ERK1/2 pathway

The lncRNA HOXA11‐AS acts as a tumor promoter in breast cancer through regulation of the miR‐125a‐5p/TMPRSS4 axis

(2022) Yunfeng Xu et al.   JOURNAL OF GENE MEDICINE

Glioma targeted therapy: insight into future of molecular approaches

(2022) Keyang Yang et al.   Molecular Cancer

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

CTHRC1 promotes growth, migration and invasion of trophoblasts via reciprocal Wnt/β-catenin regulation

(2021) Yan Li et al.   Journal of Cell Communication and Signaling

Pan-cancer analysis combined with experiments predicts CTHRC1 as a therapeutic target for human cancers

(2021) Dazhao Peng et al.   Cancer Cell International

Decreased expression of ATF3, orchestrated by β-catenin/TCF3, miR-17-5p and HOXA11-AS, promoted gastric cancer progression via increased β-catenin and CEMIP

(2021) Guohua Xie et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer

(2020) Eric C. Cheung et al.   CANCER CELL

Regulation of long non-coding RNAs and genome dynamics by the RNA surveillance machinery

(2020) Lekha Nair et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Exosomal noncoding RNAs in Glioma: biological functions and potential clinical applications

(2020) Jian Cheng et al.   Molecular Cancer

Oxidative Stress in Cancer

(2020) John D. Hayes et al.   CANCER CELL

β-catenin-TCF/LEF signaling promotes steady-state and emergency granulopoiesis via G-CSF receptor upregulation

(2020) Petr Danek et al.   BLOOD

Endogenous Labile Iron Pool-Mediated Free Radical Generation for Cancer Chemodynamic Therapy

(2020) Lisen Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeted design and identification of AC1NOD4Q to block activity of HOTAIR by abrogating the scaffold interaction with EZH2

(2019) Yu Ren et al.   Clinical Epigenetics

β-Thujaplicin induces autophagic cell death, apoptosis, and cell cycle arrest through ROS-mediated Akt and p38/ERK MAPK signaling in human hepatocellular carcinoma

(2019) Guangya Zhang et al.   Cell Death & Disease

Hacking the Cancer Genome: Profiling Therapeutically Actionable Long Non-coding RNAs Using CRISPR-Cas9 Screening

(2019) Roberta Esposito et al.   CANCER CELL

GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis

(2019) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

The combination ofTPL2knockdown and TNFα causes synthetic lethality via caspase-8 activation in human carcinoma cell lines

(2019) Oksana B. Serebrennikova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An expanded landscape of human long noncoding RNA

(2019) Shuai Jiang et al.   NUCLEIC ACIDS RESEARCH

HOXA11-AS promotes the migration and invasion of hepatocellular carcinoma cells by inhibiting miR-124 expression by binding to EZH2

(2019) Wen-long Zhang et al.   Human Cell

Silencing of long noncoding RNA HOXA11-AS inhibits the Wnt signaling pathway via the upregulation of HOXA11 and thereby inhibits the proliferation, invasion, and self-renewal of hepatocellular carcinoma stem cells

(2019) Jun-Cheng Guo et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

CTHRC1 overexpression promotes ectopic endometrial stromal cell proliferation, migration and invasion via activation of the Wnt/β-catenin pathway

(2019) Yifei Lv et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Reactive Oxygen Species in Plant Signaling

(2018) Cezary Waszczak et al.   Annual Review of Plant Biology

Functional Classification and Experimental Dissection of Long Noncoding RNAs

(2018) Florian Kopp et al.   CELL

LncRNA HOXA11-AS promotes hepatocellular carcinoma progression by repressing miR-214-3p

(2018) Meixiao Zhan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

HOXA11-AS promotes the growth and invasion of renal cancer by sponging miR-146b-5p to upregulate MMP16 expression

(2018) Feng-Qiang Yang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

New insights into long noncoding RNAs and their roles in glioma

(2018) Zixuan Peng et al.   Molecular Cancer

ROS signalling in the biology of cancer

(2018) Jennifer N. Moloney et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis 

(2018) Bo Zhou et al.   CELL RESEARCH

TCF/LEF dependent and independent transcriptional regulation of Wnt/β‐catenin target genes

(2018) Nikolaos Doumpas et al.   EMBO JOURNAL

Revealing lncRNA Structures and Interactions by Sequencing-Based Approaches

(2018) Xingyang Qian et al.   TRENDS IN BIOCHEMICAL SCIENCES

ROS and the DNA damage response in cancer

(2018) Upadhyayula Sai Srinivas et al.   Redox Biology

LncATLAS database for subcellular localization of long noncoding RNAs

(2017) David Mas-Ponte et al.   RNA

Low-grade slightly elevated and polypoid colorectal adenomas display differential β-catenin-TCF/LEF activity, c-Myc, and cyclin D1 expression

(2017) Tian-Wen Yang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Intracellularly Acid-Switchable Multifunctional Micelles for Combinational Photo/Chemotherapy of the Drug-Resistant Tumor

(2016) Tingting Wang et al.   ACS Nano

A novel cell cycle-associated lncRNA, HOXA11-AS, is transcribed from the 5-prime end of the HOXA transcript and is a biomarker of progression in glioma

(2016) Qixue Wang et al.   CANCER LETTERS

TPL2 Is an Oncogenic Driver in Keratocanthoma and Squamous Cell Carcinoma

(2016) Jun-Han Lee et al.   CANCER RESEARCH

Local regulation of gene expression by lncRNA promoters, transcription and splicing

(2016) Jesse M. Engreitz et al.   NATURE

Compromised MAPK signaling in human diseases: an update

(2015) Eun Kyung Kim et al.   ARCHIVES OF TOXICOLOGY

A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer

(2015) Edward J. Richards et al.   Oncotarget

Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release

(2014) Dmitry B. Zorov et al.   PHYSIOLOGICAL REVIEWS