β-Thujaplicin induces autophagic cell death, apoptosis, and cell cycle arrest through ROS-mediated Akt and p38/ERK MAPK signaling in human hepatocellular carcinoma

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial

(2018) Masatoshi Kudo et al.   LANCET

Treatment of β-thujaplicin counteracts di(2-ethylhexyl)phthalate (DEHP)-exposed vascular smooth muscle activation, inflammation and atherosclerosis progression

(2018) Mei Fen Shih et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies

(2018) Balaraman Kalyanaraman et al.   Redox Biology

Autophagy induction for the treatment of cancer

(2016) Federico Pietrocola et al.   Autophagy

“Hepatocellular carcinoma: A life-threatening disease”

(2016) Shinu Chacko et al.   BIOMEDICINE & PHARMACOTHERAPY

Roles of p38α mitogen-activated protein kinase in mouse models of inflammatory diseases and cancer

(2015) Jalaj Gupta et al.   FEBS Journal

Downregulation of cancer stem cell properties via mTOR signaling pathway inhibition by rapamycin in nasopharyngeal carcinoma

(2015) CHUNGUANG YANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Cell Death Signaling

(2015) Douglas R. Green et al.   Cold Spring Harbor Perspectives in Biology

Hinokitiol Induces DNA Damage and Autophagy followed by Cell Cycle Arrest and Senescence in Gefitinib-Resistant Lung Adenocarcinoma Cells

(2014) Lan-Hui Li et al.   PLoS One

Regulation of autophagy by polyphenolic compounds as a potential therapeutic strategy for cancer

(2014) N Hasima et al.   Cell Death & Disease

Hinokitiol Inhibits Cell Growth through Induction of S-Phase Arrest and Apoptosis in Human Colon Cancer Cells and Suppresses Tumor Growth in a Mouse Xenograft Experiment

(2013) Youn-Sun Lee et al.   JOURNAL OF NATURAL PRODUCTS

In vitro antimicrobial and anticancer potential of hinokitiol against oral pathogens and oral cancer cell lines

(2013) Yin-Hua Shih et al.   MICROBIOLOGICAL RESEARCH

Effect of mouth cleaning with hinokitiol-containing gel on oral malodor: a randomized, open-label pilot study

(2013) Kosaku Iha et al.   Oral Surgery Oral Medicine Oral Pathology Oral Radiology

Cross-talk between mitogenic Ras/MAPK and survival PI3K/Akt pathways: a fine balance

(2012) Edita Aksamitiene et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Rapamycin-mediated mTOR inhibition attenuates survivin and sensitizes glioblastoma cells to radiation therapy

(2011) Arunkumar Anandharaj et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

ERK activation increases nitroprusside induced apoptosis in  human melanoma  cells  irrespective of p53 status: Role of  superoxide dismutases

(2010) Luis Alberto Gomez–Sarosi et al.   CANCER BIOLOGY & THERAPY

Interactome Mapping of the Phosphatidylinositol 3-Kinase-Mammalian Target of Rapamycin Pathway Identifies Deformed Epidermal Autoregulatory Factor-1 as a New Glycogen Synthase Kinase-3 Interactor

(2010) Fanny Pilot-Storck et al.   MOLECULAR & CELLULAR PROTEOMICS

A human MAP kinase interactome

(2010) Sourav Bandyopadhyay et al.   NATURE METHODS

ERK and cell death: Mechanisms of ERK-induced cell death - apoptosis, autophagy and senescence

(2009) Sebastien Cagnol et al.   FEBS Journal

Dysregulation of apoptosis in hepatocellular carcinoma cells

(2009) Isabel Fabregat   WORLD JOURNAL OF GASTROENTEROLOGY

Hinokitiol, a Natural Tropolone Derivative, Inhibits TNF-α Production in LPS-Activated Macrophages via Suppression of NF-κB

(2008) Se Byeon et al.   PLANTA MEDICA