Targeted Protein Degradation Technology and Nanomedicine: Powerful Allies against Cancer
出版年份 2023 全文链接
标题
Targeted Protein Degradation Technology and Nanomedicine: Powerful Allies against Cancer
作者
关键词
-
出版物
Small
Volume -, Issue -, Pages 2207778
出版商
Wiley
发表日期
2023-01-25
DOI
10.1002/smll.202207778
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Susceptibility of Lung Carcinoma Cells to Nanostructured Lipid Carrier of ARV-825, a BRD4 Degrading Proteolysis Targeting Chimera
- (2022) Richa Vartak et al. PHARMACEUTICAL RESEARCH
- The AUTOTAC chemical biology platform for targeted protein degradation via the autophagy-lysosome system
- (2022) Chang Hoon Ji et al. Nature Communications
- Engineered bioorthogonal POLY-PROTAC nanoparticles for tumour-specific protein degradation and precise cancer therapy
- (2022) Jing Gao et al. Nature Communications
- Antibody targeting of E3 ubiquitin ligases for receptor degradation
- (2022) Hadir Marei et al. NATURE
- Targeting drugs to tumours using cell membrane-coated nanoparticles
- (2022) Ronnie H. Fang et al. Nature Reviews Clinical Oncology
- Versatile Nano‐PROTAC‐Induced Epigenetic Reader Degradation for Efficient Lung Cancer Therapy
- (2022) Huan‐Tian Zhang et al. Advanced Science
- Checkpoint Nano‐PROTACs for Activatable Cancer Photo‐Immunotherapy
- (2022) Chi Zhang et al. ADVANCED MATERIALS
- Small-molecule PROTAC mediates targeted protein degradation to treat STAT3-dependent epithelial cancer
- (2022) Jinmei Jin et al. JCI Insight
- Development of Antibody-Based PROTACs for the Degradation of the Cell-Surface Immune Checkpoint Protein PD-L1
- (2021) Adam D. Cotton et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Bispecific Aptamer Chimeras Enable Targeted Protein Degradation on Cell Membranes
- (2021) Da Han et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Development of Triantennary N-Acetylgalactosamine Conjugates as Degraders for Extracellular Proteins
- (2021) Yaxian Zhou et al. ACS Central Science
- Targeted drug delivery strategies for precision medicines
- (2021) Mandana T. Manzari et al. Nature Reviews Materials
- Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome
- (2021) Mathieu Bourdenx et al. CELL
- LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation
- (2021) Green Ahn et al. Nature Chemical Biology
- Targeted protein degraders crowd into the clinic
- (2021) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- Semiconducting polymer nano-PROTACs for activatable photo-immunometabolic cancer therapy
- (2021) Chi Zhang et al. Nature Communications
- Aptamer‐PROTAC Conjugates (APCs) for Tumor‐Specific Targeting in Breast Cancer
- (2021) Shipeng He et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Degradation of lipid droplets by chimeric autophagy-tethering compounds
- (2021) Yuhua Fu et al. CELL RESEARCH
- Carnosic acid-induced co-self-assembly of metal-peptide complexes into a nanocluster-based framework with tumor-specific accumulation for augmented immunotherapy
- (2021) Jin Yan et al. CHEMICAL ENGINEERING JOURNAL
- Molecular Glues for Targeted Protein Degradation: From Serendipity to Rational Discovery
- (2021) Guoqiang Dong et al. JOURNAL OF MEDICINAL CHEMISTRY
- TF-PROTACs Enable Targeted Degradation of Transcription Factors
- (2021) Jing Liu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Bifunctional small molecules that mediate the degradation of extracellular proteins
- (2021) David F. Caianiello et al. Nature Chemical Biology
- Chemistry of Lipid Nanoparticles for RNA Delivery
- (2021) Yulia Eygeris et al. ACCOUNTS OF CHEMICAL RESEARCH
- Smart Nano‐PROTACs Reprogram Tumor Microenvironment for Activatable Photo‐metabolic Cancer Immunotherapy
- (2021) Chi Zhang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Developments of CRBN-based PROTACs as potential therapeutic agents
- (2021) Chao Wang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Covalently Engineered Nanobody Chimeras for Targeted Membrane Protein Degradation
- (2021) Heng Zhang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Targeted degradation of anaplastic lymphoma kinase by gold nanoparticle-based multi-headed proteolysis targeting chimeras
- (2020) Yingming Wang et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Fundamental aspects of DMPK optimization of targeted protein degraders
- (2020) Carina Cantrill et al. DRUG DISCOVERY TODAY
- PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics
- (2020) Sajid Khan et al. ONCOGENE
- Nanoformulation of PROteolysis TArgeting Chimera targeting ‘undruggable’ c-Myc for the treatment of pancreatic cancer
- (2020) Aishwarya Saraswat et al. Nanomedicine
- Lysosome-targeting chimaeras for degradation of extracellular proteins
- (2020) Steven M. Banik et al. NATURE
- Targeted protein degradation as a powerful research tool in basic biology and drug target discovery
- (2020) Tao Wu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- PROTAC-DB: an online database of PROTACs
- (2020) Gaoqi Weng et al. NUCLEIC ACIDS RESEARCH
- Controlled Delivery of BET-PROTACs: In Vitro Evaluation of MZ1-Loaded Polymeric Antibody Conjugated Nanoparticles in Breast Cancer
- (2020) Francisco J. Cimas et al. Pharmaceutics
- RNA‐PROTACs: Degraders of RNA‐Binding Proteins
- (2020) Alice Ghidini et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Small-molecule-induced polymerization triggers degradation of BCL6
- (2020) Mikołaj Słabicki et al. NATURE
- Engineering precision nanoparticles for drug delivery
- (2020) Michael J. Mitchell et al. NATURE REVIEWS DRUG DISCOVERY
- N-degron and C-degron pathways of protein degradation
- (2019) Alexander Varshavsky PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rational Design of Nanocarriers for Intracellular Protein Delivery
- (2019) Xiaofei Qin et al. ADVANCED MATERIALS
- BRD4 PROTAC as a novel therapeutic approach for the treatment of vemurafenib resistant melanoma: Preformulation studies, formulation development and in vitro evaluation
- (2019) Drishti Rathod et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds
- (2019) Zhaoyang Li et al. NATURE
- Smart cancer nanomedicine
- (2019) Roy van der Meel et al. Nature Nanotechnology
- Cellular quality control by the ubiquitin-proteasome system and autophagy
- (2019) Christian Pohl et al. SCIENCE
- AUTACs: Cargo-Specific Degraders Using Selective Autophagy
- (2019) Daiki Takahashi et al. MOLECULAR CELL
- Cell Membrane Coating Nanotechnology
- (2018) Ronnie H. Fang et al. ADVANCED MATERIALS
- Gold Nanoparticles in Diagnostics and Therapeutics for Human Cancer
- (2018) Priyanka Singh et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The dTAG system for immediate and target-specific protein degradation
- (2018) Behnam Nabet et al. Nature Chemical Biology
- The coming of age of chaperone-mediated autophagy
- (2018) Susmita Kaushik et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mechanisms of clathrin-mediated endocytosis
- (2018) Marko Kaksonen et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Role of platelets and platelet receptors in cancer metastasis
- (2018) Martin Schlesinger Journal of Hematology & Oncology
- Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel–Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7
- (2018) Vittoria Zoppi et al. JOURNAL OF MEDICINAL CHEMISTRY
- HIP1R targets PD-L1 to lysosomal degradation to alter T cell–mediated cytotoxicity
- (2018) Huanbin Wang et al. Nature Chemical Biology
- Nanobody immunostaining for correlated light and electron microscopy with preservation of ultrastructure
- (2018) Tao Fang et al. NATURE METHODS
- PLGA-Based Nanoparticles in Cancer Treatment
- (2018) Sima Rezvantalab et al. Frontiers in Pharmacology
- Recent advances in green nanoparticulate systems for drug delivery: efficient delivery and safety concern
- (2017) Pik-Ling Lam et al. Nanomedicine
- Expanding and reprogramming the genetic code
- (2017) Jason W. Chin NATURE
- Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15
- (2017) Ting Han et al. SCIENCE
- p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis
- (2017) Hyunjoo Cha-Molstad et al. Nature Communications
- Liposomal Formulations in Clinical Use: An Updated Review
- (2017) Upendra Bulbake et al. Pharmaceutics
- Small-Molecule PROTACS: New Approaches to Protein Degradation
- (2016) Momar Toure et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase
- (2016) Mary E. Matyskiela et al. NATURE
- Induced protein degradation: an emerging drug discovery paradigm
- (2016) Ashton C. Lai et al. NATURE REVIEWS DRUG DISCOVERY
- The Autophagy–Lysosomal Pathway in Neurodegeneration: A TFEB Perspective
- (2016) Heidi Martini-Stoica et al. TRENDS IN NEUROSCIENCES
- Biodegradable Polymeric Nanoparticles as the Delivery Carrier for Drug
- (2016) Kai Zhao et al. Current Drug Delivery
- Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4
- (2015) Michael Zengerle et al. ACS Chemical Biology
- Nanomedicine in cancer therapy: Challenges, opportunities, and clinical applications
- (2015) Andreas Wicki et al. JOURNAL OF CONTROLLED RELEASE
- Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS
- (2015) Jan Krönke et al. NATURE
- Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding
- (2015) Hyunjoo Cha-Molstad et al. NATURE CELL BIOLOGY
- Catalytic in vivo protein knockdown by small-molecule PROTACs
- (2015) Daniel P Bondeson et al. Nature Chemical Biology
- Phthalimide conjugation as a strategy for in vivo target protein degradation
- (2015) G. E. Winter et al. SCIENCE
- Red Blood Cell Membrane as a Biomimetic Nanocoating for Prolonged Circulation Time and Reduced Accelerated Blood Clearance
- (2015) Lang Rao et al. Small
- Rapid and reversible knockdown of endogenous proteins by peptide-directed lysosomal degradation
- (2014) Xuelai Fan et al. NATURE NEUROSCIENCE
- Endogenous Nitrated Nucleotide Is a Key Mediator of Autophagy and Innate Defense against Bacteria
- (2013) Chiaki Ito et al. MOLECULAR CELL
- mTOR kinase structure, mechanism and regulation
- (2013) Haijuan Yang et al. NATURE
- Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells
- (2013) J. Kronke et al. SCIENCE
- Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide
- (2012) A Lopez-Girona et al. LEUKEMIA
- Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors
- (2012) Bon-Kyoung Koo et al. NATURE
- Cancer Theranostics with Near-Infrared Light-Activatable Multimodal Nanoparticles
- (2011) Marites P. Melancon et al. ACCOUNTS OF CHEMICAL RESEARCH
- Bio-inspired, bioengineered and biomimetic drug delivery carriers
- (2011) Jin-Wook Yoo et al. NATURE REVIEWS DRUG DISCOVERY
- Two-Headed PROTAC: An Effective New Tool for Targeted Protein Degradation
- (2010) Kedra Cyrus et al. CHEMBIOCHEM
- Gold nanostructures: a class of multifunctional materials for biomedical applications
- (2010) Claire M. Cobley et al. CHEMICAL SOCIETY REVIEWS
- Protein Knockdown Using Methyl Bestatin−Ligand Hybrid Molecules: Design and Synthesis of Inducers of Ubiquitination-Mediated Degradation of Cellular Retinoic Acid-Binding Proteins
- (2010) Yukihiro Itoh et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Targeted intracellular protein degradation induced by a small molecule: En route to chemical proteomics
- (2008) Ashley R. Schneekloth et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now