标题
Bifunctional small molecules that mediate the degradation of extracellular proteins
作者
关键词
-
出版物
Nature Chemical Biology
Volume 17, Issue 9, Pages 947-953
出版商
Springer Science and Business Media LLC
发表日期
2021-08-20
DOI
10.1038/s41589-021-00851-1
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Development of Antibody-Based PROTACs for the Degradation of the Cell-Surface Immune Checkpoint Protein PD-L1
- (2021) Adam D. Cotton et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Development of Triantennary N-Acetylgalactosamine Conjugates as Degraders for Extracellular Proteins
- (2021) Yaxian Zhou et al. ACS Central Science
- Lysosome-targeting chimaeras for degradation of extracellular proteins
- (2020) Steven M. Banik et al. NATURE
- A Review of PCSK9 Inhibitors and their effects on cardiovascular disease
- (2019) Bo Chen et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Macrophage migration inhibitory factor (MIF) as a therapeutic target for rheumatoid arthritis and systemic lupus erythematosus
- (2019) Joshua B. Bilsborrow et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis
- (2018) Jonathan Martínez-Fábregas et al. Nature Communications
- Asialoglycoprotein receptor 1 mediates productive uptake of N-acetylgalactosamine-conjugated and unconjugated phosphorothioate antisense oligonucleotides into liver hepatocytes
- (2017) Michael Tanowitz et al. NUCLEIC ACIDS RESEARCH
- Distinct effects of endosomal escape and inhibition of endosomal trafficking on gene delivery via electrotransfection
- (2017) Lisa D. Cervia et al. PLoS One
- Well-Defined Multivalent Ligands for Hepatocytes Targeting via Asialoglycoprotein Receptor
- (2016) Xiangang Huang et al. BIOCONJUGATE CHEMISTRY
- A Fluorescence Polarization Assay for Binding to Macrophage Migration Inhibitory Factor and Crystal Structures for Complexes of Two Potent Inhibitors
- (2016) José A. Cisneros et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- siRNA Conjugates Carrying Sequentially Assembled Trivalent N-Acetylgalactosamine Linked Through Nucleosides Elicit Robust Gene Silencing In Vivo in Hepatocytes
- (2015) Shigeo Matsuda et al. ACS Chemical Biology
- Selectivity of commonly used inhibitors of clathrin-mediated and caveolae-dependent endocytosis of G protein–coupled receptors
- (2015) Shuohan Guo et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Structural glycobiology of human α1-acid glycoprotein and its implications for pharmacokinetics and inflammation
- (2015) Cláudia L Fernandes et al. GLYCOBIOLOGY
- Asialoglycoprotein receptor mediated hepatocyte targeting — Strategies and applications
- (2015) Anisha A. D'Souza et al. JOURNAL OF CONTROLLED RELEASE
- Design, Synthesis, and Protein Crystallography of Biaryltriazoles as Potent Tautomerase Inhibitors of Macrophage Migration Inhibitory Factor
- (2015) Pawel Dziedzic et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- TNF biology, pathogenic mechanisms and emerging therapeutic strategies
- (2015) George D. Kalliolias et al. Nature Reviews Rheumatology
- An intrinsic mechanism of secreted protein aging and turnover
- (2015) Won Ho Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modulation of Mannose and Asialoglycoprotein Receptor Expression Determines Glycoprotein Hormone Half-life at Critical Points in the Reproductive Cycle
- (2014) Yiling Mi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Ashwell-Morell receptor regulates hepatic thrombopoietin production via JAK2-STAT3 signaling
- (2014) Renata Grozovsky et al. NATURE MEDICINE
- Expression of Asialoglycoprotein Receptor 1 in Human Hepatocellular Carcinoma
- (2013) Bin Shi et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- A Comprehensive Mathematical Model for Three-Body Binding Equilibria
- (2013) Eugene F. Douglass et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- NMR study of ligand release from asialoglycoprotein receptor under solution conditions in early endosomes
- (2012) Takuo Onizuka et al. FEBS Journal
- Glycomimetic Ligands for the Human Asialoglycoprotein Receptor
- (2012) Sreeman K. Mamidyala et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Dihydroartemisinin Exerts Its Anticancer Activity through Depleting Cellular Iron via Transferrin Receptor-1
- (2012) Qian Ba et al. PLoS One
- Hepatocyte cytotoxicity is facilitated by asialoglycoprotein receptor
- (2011) Clifford S. Guy et al. HEPATOLOGY
- Hepatocyte entry leads to degradation of autoreactive CD8 T cells
- (2011) V. Benseler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hepatocyte Targeting and Intracellular Copper Chelation by a Thiol-Containing Glycocyclopeptide
- (2010) Anaïs M. Pujol et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms
- (2010) Akin Akinc et al. MOLECULAR THERAPY
- The Asialoglycoprotein Receptor Regulates Levels of Plasma Glycoproteins Terminating with Sialic Acid α2,6-Galactose
- (2008) Lindsay M. Steirer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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