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The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution

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Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma

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A human liver cell atlas reveals heterogeneity and epithelial progenitors

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Tumor Cell Biodiversity Drives Microenvironmental Reprogramming in Liver Cancer

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Functional Genomic Complexity Defines Intratumor Heterogeneity and Tumor Aggressiveness in Liver Cancer

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The multiple functions and mechanisms of osteopontin

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A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex

(2018) Suijuan Zhong et al.   NATURE

Global characterization of T cells in non-small-cell lung cancer by single-cell sequencing

(2018) Xinyi Guo et al.   NATURE MEDICINE

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

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Single-cell reconstruction of the early maternal–fetal interface in humans

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Lineage tracking reveals dynamic relationships of T cells in colorectal cancer

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Genome-wide CRISPR screens reveal synthetic lethality of RNASEH2 deficiency and ATR inhibition

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Tremelimumab in combination with ablation in patients with advanced hepatocellular carcinoma

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Reversed graph embedding resolves complex single-cell trajectories

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Toward understanding and exploiting tumor heterogeneity

(2015) Ash A Alizadeh et al.   NATURE MEDICINE

Pan-cancer analysis of the extent and consequences of intratumor heterogeneity

(2015) Noemi Andor et al.   NATURE MEDICINE

HCC therapies—lessons learned

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Mechanisms underlying mutational signatures in human cancers

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The Ecology of Collective Behavior

(2014) Deborah M. Gordon   PLOS BIOLOGY

Influence of tumour micro-environment heterogeneity on therapeutic response

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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

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