Disease modification and symptom relief in osteoarthritis using a mutated GCP ‐2/ CXCL6 chemokine

In vivo potency assay for the screening of bioactive molecules on cartilage formation

(2022) Anne-Sophie Thorup et al.   LAB ANIMAL

Heparan Sulfate Deficiency in Cartilage: Enhanced BMP-Sensitivity, Proteoglycan Production and an Anti-Apoptotic Expression Signature after Loading

(2021) Matthias Gerstner et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

BCP crystals promote chondrocyte hypertrophic differentiation in OA cartilage by sequestering Wnt3a

(2020) Jessica Bertrand et al.   ANNALS OF THE RHEUMATIC DISEASES

Lessons from joint development for cartilage repair in the clinic

(2020) Anne‐Sophie Thorup et al.   DEVELOPMENTAL DYNAMICS

Glycosaminoglycan–Protein Interactions: The First Draft of the Glycosaminoglycan Interactome

(2020) Sylvain D. Vallet et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Agrin induces long-term osteochondral regeneration by supporting repair morphogenesis

(2020) Suzanne E. Eldridge et al.   Science Translational Medicine

ROR2 blockade as a therapy for osteoarthritis

(2020) Anne-Sophie Thorup et al.   Science Translational Medicine

Perspectives on the Biological Role of Chemokine:Glycosaminoglycan Interactions

(2020) Tracy M. Handel et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Effect of Tanezumab on Joint Pain, Physical Function, and Patient Global Assessment of Osteoarthritis Among Patients With Osteoarthritis of the Hip or Knee

(2019) Thomas J. Schnitzer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis

(2019) Marc C. Hochberg et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Connective tissue growth factor contributes to joint homeostasis and osteoarthritis severity by controlling the matrix sequestration and activation of latent TGFβ

(2018) Xiaodi Tang et al.   ANNALS OF THE RHEUMATIC DISEASES

Protein engineering of the chemokine CCL20 prevents psoriasiform dermatitis in an IL-23–dependent murine model

(2017) A. E. Getschman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis

(2016) Giovanna Nalesso et al.   ANNALS OF THE RHEUMATIC DISEASES

Osteoarthritis

(2016) Johanne Martel-Pelletier et al.   Nature Reviews Disease Primers

Halofuginone attenuates osteoarthritis by inhibition of TGF-β activity and H-type vessel formation in subchondral bone

(2015) Zhuang Cui et al.   ANNALS OF THE RHEUMATIC DISEASES

Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo

(2015) Suzanne Eldridge et al.   ANNALS OF THE RHEUMATIC DISEASES

Serious joint-related adverse events in randomized controlled trials of anti-nerve growth factor monoclonal antibodies

(2015) M.C. Hochberg   OSTEOARTHRITIS AND CARTILAGE

A homeostatic function of CXCR2 signalling in articular cartilage

(2014) Joanna Sherwood et al.   ANNALS OF THE RHEUMATIC DISEASES

TSG-6 Inhibits Neutrophil Migration via Direct Interaction with the Chemokine CXCL8

(2014) D. P. Dyer et al.   JOURNAL OF IMMUNOLOGY

Tissue-Specific Host Recognition by Complement Factor H Is Mediated by Differential Activities of Its Glycosaminoglycan-Binding Regions

(2013) S. J. Clark et al.   JOURNAL OF IMMUNOLOGY

Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis

(2013) Gehua Zhen et al.   NATURE MEDICINE

Health economics in the field of osteoarthritis: An Expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)

(2013) Mickaël Hiligsmann et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Loss of NPP1 induces cartilage remodelling into bone and OA-like changes in mice

(2011) J. Bertrand et al.   ANNALS OF THE RHEUMATIC DISEASES

WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways

(2011) Giovanna Nalesso et al.   JOURNAL OF CELL BIOLOGY

Clinical Outcomes of Characterized Chondrocyte Implantation

(2011) Johan Vanlauwe et al.   Cartilage

BoneJ: Free and extensible bone image analysis in ImageJ

(2010) Michael Doube et al.   BONE

Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development

(2010) Taku Saito et al.   NATURE MEDICINE

Hypoxia-inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction

(2010) Siyoung Yang et al.   NATURE MEDICINE

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse

(2010) S.S. Glasson et al.   OSTEOARTHRITIS AND CARTILAGE

Treatment of Symptomatic Cartilage Defects of the Knee

(2009) Daniel B. F. Saris et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Matrix metalloproteinase 13–deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development

(2009) C. B. Little et al.   ARTHRITIS AND RHEUMATISM

Differential expression of GADD45β in normal and osteoarthritic cartilage: Potential role in homeostasis of articular chondrocytes

(2008) Kosei Ijiri et al.   ARTHRITIS AND RHEUMATISM