标题
ROR2 blockade as a therapy for osteoarthritis
作者
关键词
-
出版物
Science Translational Medicine
Volume 12, Issue 561, Pages eaax3063
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2020-09-17
DOI
10.1126/scitranslmed.aax3063
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeting of Antithrombin in Hemophilia A or B with RNAi Therapy
- (2017) K. John Pasi et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Highly Durable RNAi Therapeutic Inhibitor of PCSK9
- (2017) Kevin Fitzgerald et al. NEW ENGLAND JOURNAL OF MEDICINE
- WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis
- (2016) Giovanna Nalesso et al. ANNALS OF THE RHEUMATIC DISEASES
- Cyclic Mechanical Loading Enhances Transport of Antibodies Into Articular Cartilage
- (2016) Chris D. DiDomenico et al. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME
- Identification of Targets of a New Nutritional Mixture for Osteoarthritis Management Composed by Curcuminoids Extract, Hydrolyzed Collagen and Green Tea Extract
- (2016) Fanny Comblain et al. PLoS One
- The in Vivo Effect of Prophylactic Subchondral Bone Protection of Osteoarthritic Synovial Membrane in Bone-Specific Ephb4-Overexpressing Mice
- (2015) Gladys Valverde-Franco et al. AMERICAN JOURNAL OF PATHOLOGY
- Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo
- (2015) Suzanne Eldridge et al. ANNALS OF THE RHEUMATIC DISEASES
- Alternative Wnt Signaling Activates YAP/TAZ
- (2015) Hyun Woo Park et al. CELL
- Wnt5a induces ROR1/ROR2 heterooligomerization to enhance leukemia chemotaxis and proliferation
- (2015) Jian Yu et al. JOURNAL OF CLINICAL INVESTIGATION
- Mongersen, an Oral SMAD7 Antisense Oligonucleotide, and Crohn’s Disease
- (2015) Giovanni Monteleone et al. NEW ENGLAND JOURNAL OF MEDICINE
- Intermittent applied mechanical loading induces subchondral bone thickening that may be intensified locally by contiguous articular cartilage lesions
- (2015) B. Poulet et al. OSTEOARTHRITIS AND CARTILAGE
- A homeostatic function of CXCR2 signalling in articular cartilage
- (2014) Joanna Sherwood et al. ANNALS OF THE RHEUMATIC DISEASES
- Inducible chondrocyte-specific overexpression of BMP2 in young mice results in severe aggravation of osteophyte formation in experimental OA without altering cartilage damage
- (2014) E N Blaney Davidson et al. ANNALS OF THE RHEUMATIC DISEASES
- Cellular and molecular mechanisms of cartilage damage and repair
- (2014) Joanna C. Sherwood et al. DRUG DISCOVERY TODAY
- The Hippo signaling pathway in stem cell biology and cancer
- (2014) J.-S. Mo et al. EMBO REPORTS
- Current and future impact of osteoarthritis on health care: a population-based study with projections to year 2032
- (2014) A. Turkiewicz et al. OSTEOARTHRITIS AND CARTILAGE
- Live Imaging of Xwnt5A-ROR2 Complexes
- (2014) Veronika Wallkamm et al. PLoS One
- Inactivation of evenness interrupted (EVI) reduces experimental fibrosis by combined inhibition of canonical and non-canonical Wnt signalling
- (2013) Alfiya Distler et al. ANNALS OF THE RHEUMATIC DISEASES
- Transport of anti-IL-6 antigen binding fragments into cartilage and the effects of injury
- (2013) Sangwon Byun et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Fibroblast Growth Factor 2 Drives Changes in Gene Expression Following Injury to Murine Cartilage In Vitro and In Vivo
- (2013) Ka-Wing Chong et al. ARTHRITIS AND RHEUMATISM
- Gene expression profiling of dedifferentiated human articular chondrocytes in monolayer culture
- (2013) B. Ma et al. OSTEOARTHRITIS AND CARTILAGE
- The epidemiology and impact of pain in osteoarthritis
- (2013) T. Neogi OSTEOARTHRITIS AND CARTILAGE
- Disease Progression and Phasic Changes in Gene Expression in a Mouse Model of Osteoarthritis
- (2013) Richard F. Loeser et al. PLoS One
- Health economics in the field of osteoarthritis: An Expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
- (2013) Mickaël Hiligsmann et al. SEMINARS IN ARTHRITIS AND RHEUMATISM
- Risk of sick leave and disability pension in working-age women and men with knee osteoarthritis
- (2012) Jenny Hubertsson et al. ANNALS OF THE RHEUMATIC DISEASES
- NIH Image to ImageJ: 25 years of image analysis
- (2012) Caroline A Schneider et al. NATURE METHODS
- Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis
- (2012) M. C. Castano Betancourt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Stem Cell-Based Approach to Cartilage Repair
- (2012) K. Johnson et al. SCIENCE
- Autophagy activation by rapamycin reduces severity of experimental osteoarthritis
- (2011) Beatriz Caramés et al. ANNALS OF THE RHEUMATIC DISEASES
- Wnt Signaling Gradients Establish Planar Cell Polarity by Inducing Vangl2 Phosphorylation through Ror2
- (2011) Bo Gao et al. DEVELOPMENTAL CELL
- WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways
- (2011) Giovanna Nalesso et al. JOURNAL OF CELL BIOLOGY
- Teriparatide as a Chondroregenerative Therapy for Injury-Induced Osteoarthritis
- (2011) E. R. Sampson et al. Science Translational Medicine
- Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors
- (2010) L. Grumolato et al. GENES & DEVELOPMENT
- Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development
- (2010) Taku Saito et al. NATURE MEDICINE
- Hypoxia-inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction
- (2010) Siyoung Yang et al. NATURE MEDICINE
- Bone Morphogenetic Proteins and articular cartilage
- (2010) P.M. van der Kraan et al. OSTEOARTHRITIS AND CARTILAGE
- The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse
- (2010) S.S. Glasson et al. OSTEOARTHRITIS AND CARTILAGE
- Insurer and out-of-pocket costs of osteoarthritis in the US: Evidence from national survey data
- (2009) Harry Kotlarz et al. ARTHRITIS AND RHEUMATISM
- Ror2 Receptor Requires Tyrosine Kinase Activity to Mediate Wnt5A Signaling
- (2009) Amanda Mikels et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Differential expression of GADD45β in normal and osteoarthritic cartilage: Potential role in homeostasis of articular chondrocytes
- (2008) Kosei Ijiri et al. ARTHRITIS AND RHEUMATISM
- Fibroblast-specific perturbation of transforming growth factor β signaling provides insight into potential pathogenic mechanisms of scleroderma-associated lung fibrosis: Exaggerated response to alveolar epithelial injury in a novel mouse model
- (2008) Rachel K. Hoyles et al. ARTHRITIS AND RHEUMATISM
- Wnt5a regulates directional cell migration and cell proliferation via Ror2-mediated noncanonical pathway in mammalian palate development
- (2008) F. He et al. DEVELOPMENT
- Cthrc1 Selectively Activates the Planar Cell Polarity Pathway of Wnt Signaling by Stabilizing the Wnt-Receptor Complex
- (2008) Shinji Yamamoto et al. DEVELOPMENTAL CELL
- Radiographic osteoarthritis at three joint sites and FRZB, LRP5, and LRP6 polymorphisms in two population-based cohorts
- (2008) J.M. Kerkhof et al. OSTEOARTHRITIS AND CARTILAGE
- Deletion of frizzled-related protein reduces voluntary running exercise performance in mice
- (2008) R.J.U. Lories et al. OSTEOARTHRITIS AND CARTILAGE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now