Inhibition of KDM5A attenuates cisplatin-induced hearing loss via regulation of the MAPK/AKT pathway
出版年份 2022 全文链接
标题
Inhibition of KDM5A attenuates cisplatin-induced hearing loss via regulation of the MAPK/AKT pathway
作者
关键词
-
出版物
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 79, Issue 12, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-11-18
DOI
10.1007/s00018-022-04565-y
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The protective effect of rutin against the cisplatin-induced cochlear damage in vitro
- (2022) Shimei Zheng et al. NEUROTOXICOLOGY
- The emerging role of KDM5A in human cancer
- (2021) Guan-Jun Yang et al. Journal of Hematology & Oncology
- Metformin Alleviates Cisplatin-Induced Ototoxicity by Autophagy Induction Possibly via the AMPK/FOXO3a Pathway
- (2021) Zhengrong Liang et al. JOURNAL OF NEUROPHYSIOLOGY
- Critical requirement of SOS1 RAS-GEF function for mitochondrial dynamics, metabolism, and redox homeostasis
- (2021) Rósula García-Navas et al. ONCOGENE
- SOD2 Alleviates Hearing Loss Induced by Noise and Kanamycin in Mitochondrial DNA4834-deficient Rats by Regulating PI3K/MAPK Signaling
- (2021) Yan Zhang et al. Current Medical Science
- Pharmacological inhibition of KDM5A for cancer treatment
- (2021) Guan-Jun Yang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Inhibiting DNA methylation alleviates cisplatin-induced hearing loss by decreasing oxidative stress-induced mitochondria-dependent apoptosis via the LRP1–PI3K/AKT pathway
- (2021) Yingzi He et al. Acta Pharmaceutica Sinica B
- Co-existence of hepatocellular carcinoma and cystic echinococcosis
- (2020) Ran Bo et al. Infectious Agents and Cancer
- Peptide‐conjugated long‐lived theranostic imaging toolbox for targeting GRPr in cancer and immune cells
- (2020) Wanhe Wang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- E6 hijacks KDM5C/lnc_000231/miR‐497‐5p/CCNE1 axis to promote cervical cancer progression
- (2020) Yan Zhang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Marked synergy by vertical inhibition of EGFR signaling in NSCLC spheroids shows SOS1 is a therapeutic target in EGFR-mutated cancer
- (2020) Patricia L Theard et al. eLife
- MEKK3-MEK5-ERK5 signaling promotes mitochondrial degradation
- (2020) Jane E. Craig et al. Cell Death Discovery
- SOS GEFs in health and disease
- (2020) Fernando C. Baltanás et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Histone H3 lysine K4 methylation and its role in learning and memory
- (2019) Bridget E. Collins et al. Epigenetics & Chromatin
- Frontline Science: TNF‐α and GM‐CSF1 priming augments the role of SOS1/2 in driving activation of Ras, PI3K‐γ, and neutrophil proinflammatory responses
- (2019) Sabine Suire et al. JOURNAL OF LEUKOCYTE BIOLOGY
- KDM5C is transcriptionally regulated by BRD4 and promotes castration-resistance prostate cancer cell proliferation by repressing PTEN
- (2019) Zhe Hong et al. BIOMEDICINE & PHARMACOTHERAPY
- CUT&Tag for efficient epigenomic profiling of small samples and single cells
- (2019) Hatice S. Kaya-Okur et al. Nature Communications
- The therapeutic effect of dexmedetomidine on protection from renal failure via inhibiting KDM5A in lipopolysaccharide-induced sepsis of mice
- (2019) Yan Liu et al. LIFE SCIENCES
- Histone demethylase KDM5A inhibits glioma cells migration and invasion by down regulating ZEB1
- (2018) Bin Dai et al. BIOMEDICINE & PHARMACOTHERAPY
- Novel compounds protect auditory hair cells against gentamycin-induced apoptosis by maintaining the expression level of H3K4me2
- (2018) Ao Li et al. DRUG DELIVERY
- The histone demethylase KDM5A is required for the repression of astrocytogenesis and regulated by the translational machinery in neural progenitor cells
- (2018) Sun-Young Kong et al. FASEB JOURNAL
- KDM5 demethylases and their role in cancer cell chemoresistance
- (2018) J. Plch et al. INTERNATIONAL JOURNAL OF CANCER
- STK33 alleviates gentamicin-induced ototoxicity in cochlear hair cells and House Ear Institute-Organ of Corti 1 cells
- (2018) Meijuan Zhou et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Evaluating protective and therapeutic effects of alpha-lipoic acid on cisplatin-induced ototoxicity
- (2018) Kyung-Hee Kim et al. Cell Death & Disease
- PINK1 Protects Against Gentamicin-Induced Sensory Hair Cell Damage: Possible Relation to Induction of Autophagy and Inhibition of p53 Signal Pathway
- (2018) Qianqian Yang et al. Frontiers in Molecular Neuroscience
- Relative Initial Weight Is Associated with Improved Survival without Altering Tumor Latency in a Translational Rat Model of Diethylnitrosamine-Induced Hepatocellular Carcinoma and Transarterial Embolization
- (2017) Ryan M. Kiefer et al. JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
- KDM5A promotes proliferation and EMT in ovarian cancer and closely correlates with PTX resistance
- (2017) Tongfu Feng et al. Molecular Medicine Reports
- Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c
- (2017) Bifeng Pan et al. NATURE BIOTECHNOLOGY
- Loss of sestrin 2 potentiates the early onset of age-related sensory cell degeneration in the cochlea
- (2017) Celia Zhang et al. NEUROSCIENCE
- Cisplatin is retained in the cochlea indefinitely following chemotherapy
- (2017) Andrew M. Breglio et al. Nature Communications
- Cochlear gene therapy with ancestral AAV in adult mice: complete transduction of inner hair cells without cochlear dysfunction
- (2017) Jun Suzuki et al. Scientific Reports
- Ototoxicity and cancer therapy
- (2016) Wendy Landier CANCER
- HEI-OC1 cells as a model for investigating drug cytotoxicity
- (2016) Gilda Kalinec et al. HEARING RESEARCH
- An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells
- (2016) Maia Vinogradova et al. Nature Chemical Biology
- Sos1 disruption impairs cellular proliferation and viability through an increase in mitochondrial oxidative stress in primary MEFs
- (2016) P Liceras-Boillos et al. ONCOGENE
- Reduced TRMU expression increases the sensitivity of hair-cell-like HEI-OC-1 cells to neomycin damage in vitro
- (2016) Zuhong He et al. Scientific Reports
- Increased mitochondrial function downstream from KDM5A histone demethylase rescues differentiation in pRB-deficient cells
- (2015) Renáta Váraljai et al. GENES & DEVELOPMENT
- Perinatal Gjb2 gene transfer rescues hearing in a mouse model of hereditary deafness
- (2015) T. Iizuka et al. HUMAN MOLECULAR GENETICS
- Lysine-specific demethylase 1 inhibitors protect cochlear spiral ganglion neurons against cisplatin-induced damage
- (2015) Ao Li et al. NEUROREPORT
- The deafness gene DFNA5 induces programmed cell death through mitochondria and MAPK-related pathways
- (2015) Sofie Van Rossom et al. Frontiers in Cellular Neuroscience
- Structure and vascular function of MEKK3–cerebral cavernous malformations 2 complex
- (2015) Oriana S. Fisher et al. Nature Communications
- Exploring the Preparation of Albendazole-Loaded Chitosan-Tripolyphosphate Nanoparticles
- (2015) Bong-Seok Kang et al. Materials
- 2-Methoxyestradiol synergizes with sorafenib to suppress hepatocellular carcinoma by simultaneously dysregulating hypoxia-inducible factor-1 and -2
- (2014) Li Ma et al. CANCER LETTERS
- Inhibition of H3K4me2 Demethylation Protects Auditory Hair Cells from Neomycin-Induced Apoptosis
- (2014) Yingzi He et al. MOLECULAR NEUROBIOLOGY
- Histone Demethylase RBP2 Is Critical for Breast Cancer Progression and Metastasis
- (2014) Jian Cao et al. Cell Reports
- Histone Demethylase RBP2 Promotes Lung Tumorigenesis and Cancer Metastasis
- (2013) Y.-C. Teng et al. CANCER RESEARCH
- Functional Redundancy of Sos1 and Sos2 for Lymphopoiesis and Organismal Homeostasis and Survival
- (2013) Fernando C. Baltanás et al. MOLECULAR AND CELLULAR BIOLOGY
- Cochlear Inner Hair Cell Ribbon Synapse is the Primary Target of Ototoxic Aminoglycoside Stimuli
- (2013) Ke Liu et al. MOLECULAR NEUROBIOLOGY
- Inhibition of H3K9 methyltransferases G9a/GLP prevents ototoxicity and ongoing hair cell death
- (2013) H Yu et al. Cell Death & Disease
- The cytoprotective effect of butin against oxidative stress is mediated by the up-regulation of manganese superoxide dismutase expression through a PI3K/Akt/Nrf2-dependent pathway
- (2012) Rui Zhang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- AKT Signaling Mediates IGF-I Survival Actions on Otic Neural Progenitors
- (2012) Maria R. Aburto et al. PLoS One
- Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation
- (2012) M. L. Beshiri et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence
- (2012) A. Chicas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ototoxicity: Mechanisms of Cochlear Impairment and its Prevention
- (2011) K. Tabuchi et al. CURRENT MEDICINAL CHEMISTRY
- Genetic background effects on age-related hearing loss associated with Cdh23 variants in mice
- (2011) Kelly L. Kane et al. HEARING RESEARCH
- Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1
- (2011) W. Lin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Comparison of Cochlear Morphology and Apoptosis in Mouse Models of Presbycusis
- (2010) Shi-Nae Park et al. Clinical and Experimental Otorhinolaryngology
- The Histone Demethylase RBP2 Is Overexpressed in Gastric Cancer and Its Inhibition Triggers Senescence of Cancer Cells
- (2009) Jiping Zeng et al. GASTROENTEROLOGY
- Effects of sex, gonadal hormones, and augmented acoustic environments on sensorineural hearing loss and the central auditory system: Insights from research on C57BL/6J mice
- (2008) James F. Willott HEARING RESEARCH
- Genome-wide Analysis of the H3K4 Histone Demethylase RBP2 Reveals a Transcriptional Program Controlling Differentiation
- (2008) Nuria Lopez-Bigas et al. MOLECULAR CELL
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