Intestinal dysbiosis mediates cognitive impairment via the intestine and brain NLRP3 inflammasome activation in chronic sleep deprivation

Examining sleep deficiency and disturbance and their risk for incident dementia and all-cause mortality in older adults across 5 years in the United States

(2021) Rebecca Robbins et al.   Aging-US

Rapid gut dysbiosis induced by stroke exacerbates brain infarction in turn

(2021) Kaiyu Xu et al.   GUT

Lactobacillus plantarum ATG-K2 and ATG-K6 Ameliorates High-Fat with High-Fructose Induced Intestinal Inflammation

(2021) Miey Park et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gut microbiota modulates the inflammatory response and cognitive impairment induced by sleep deprivation

(2021) Zhong Wang et al.   MOLECULAR PSYCHIATRY

Microbiota regulate social behaviour via stress response neurons in the brain

(2021) Wei-Li Wu et al.   NATURE

Repeated sleep disruption in mice leads to persistent shifts in the fecal microbiome and metabolome

(2020) Samuel J. Bowers et al.   PLoS One

Beneficial Effects of Lactobacillus plantarum Strains on Non-Alcoholic Fatty Liver Disease in High Fat/High Fructose Diet-Fed Rats

(2020) Eun-Jung Park et al.   Nutrients

Acute Sleep-Wake Cycle Shift Results in Community Alteration of Human Gut Microbiome

(2020) Zhi Liu et al.   mSphere

Gut Microbiota and Disorders of the Central Nervous System

(2020) Claudia Vuotto et al.   NEUROSCIENTIST

New mechanism of neuroinflammation in Alzheimer's disease: The activation of NLRP3 inflammasome mediated by gut microbiota

(2020) Heping Shen et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The gut microbiota–brain axis in behaviour and brain disorders

(2020) Livia H. Morais et al.   NATURE REVIEWS MICROBIOLOGY

The Role of Microglia and the Nlrp3 Inflammasome in Alzheimer's Disease

(2020) Kendra L. Hanslik et al.   Frontiers in Neurology

The Gut-Brain Axis: How Microbiota and Host Inflammasome Influence Brain Physiology and Pathology

(2020) Andrina Rutsch et al.   Frontiers in Immunology

The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans

(2019) Jerrah K. Holth et al.   SCIENCE

Author Correction: Inflammasome signalling in brain function and neurodegenerative disease

(2019) Michael T. Heneka et al.   NATURE REVIEWS NEUROSCIENCE

Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis

(2019) Lijun Liao et al.   GUT

Phytochemicals as Novel Therapeutic Strategies for NLRP3 Inflammasome-Related Neurological, Metabolic, and Inflammatory Diseases

(2019) Carolina Pellegrini et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation

(2019) Nathan Kelley et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Complement activation sustains neuroinflammation and deteriorates adult neurogenesis and spatial memory impairment in rat hippocampus following sleep deprivation

(2019) Meetu Wadhwa et al.   BRAIN BEHAVIOR AND IMMUNITY

Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer’s disease progression

(2019) Xinyi Wang et al.   CELL RESEARCH

Transfer of a healthy microbiota reduces amyloid and tau pathology in an Alzheimer’s disease animal model

(2019) Min-Soo Kim et al.   GUT

A brief period of sleep deprivation leads to subtle changes in mouse gut microbiota

(2019) Sahar El Aidy et al.   JOURNAL OF SLEEP RESEARCH

The Microbiota-Gut-Brain Axis

(2019) John F. Cryan et al.   PHYSIOLOGICAL REVIEWS

Gut microbiota from NLRP3-deficient mice ameliorates depressive-like behaviors by regulating astrocyte dysfunction via circHIPK2

(2019) Yuan Zhang et al.   Microbiome

Combinatory antibiotic treatment protects against experimental acute pancreatitis by suppressing gut bacterial translocation to pancreas and inhibiting NLRP3 inflammasome pathway

(2019) Lingling Jia et al.   Innate Immunity

The gut microbiome in neurological disorders

(2019) John F Cryan et al.   LANCET NEUROLOGY

Microbiota and the social brain

(2019) Eoin Sherwin et al.   SCIENCE

Roles and applications of probiotic Lactobacillus strains

(2018) Zhongwang Zhang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Gut Microbiota is Altered in Patients with Alzheimer’s Disease

(2018) Zhen-Qian Zhuang et al.   JOURNAL OF ALZHEIMERS DISEASE

In vivo evidence for the contribution of peripheral circulating inflammatory exosomes to neuroinflammation

(2018) Jing Jing Li et al.   Journal of Neuroinflammation

Alzheimer’s disease and gut microbiota modifications: The long way between preclinical studies and clinical evidence

(2018) Cesare Mancuso et al.   PHARMACOLOGICAL RESEARCH

Sleep disturbances increase the risk of dementia: A systematic review and meta-analysis

(2018) Le Shi et al.   SLEEP MEDICINE REVIEWS

Short sleep duration and cardiometabolic risk: from pathophysiology to clinical evidence

(2018) Eleonora Tobaldini et al.   Nature Reviews Cardiology

Altered Gut Microbiota in a Mouse Model of Alzheimer’s Disease

(2017) Ling Zhang et al.   JOURNAL OF ALZHEIMERS DISEASE

Inflammasomes and intestinal inflammation

(2017) N Zmora et al.   Mucosal Immunology

The sleep-deprived human brain

(2017) Adam J. Krause et al.   NATURE REVIEWS NEUROSCIENCE

Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly

(2017) Annamaria Cattaneo et al.   NEUROBIOLOGY OF AGING

Sleep deprivation accelerates the progression of alzheimer’s disease by influencing Aβ-related metabolism

(2017) Lihong Chen et al.   NEUROSCIENCE LETTERS

Sleep Disturbance, Sleep Duration, and Inflammation: A Systematic Review and Meta-Analysis of Cohort Studies and Experimental Sleep Deprivation

(2016) Michael R. Irwin et al.   BIOLOGICAL PSYCHIATRY

Amyloid β induces NLRP3 inflammasome activation in retinal pigment epithelial cells via NADPH oxidase- and mitochondria-dependent ROS production

(2016) Ke Wang et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways

(2016) G B Rogers et al.   MOLECULAR PSYCHIATRY

Sleep function: Toward elucidating an enigma

(2016) James M. Krueger et al.   SLEEP MEDICINE REVIEWS

Gut microbiota and glucometabolic alterations in response to recurrent partial sleep deprivation in normal-weight young individuals

(2016) Christian Benedict et al.   Molecular Metabolism

Chronic Sleep Disruption Alters Gut Microbiota, Induces Systemic and Adipose Tissue Inflammation and Insulin Resistance in Mice

(2016) Valeriy A. Poroyko et al.   Scientific Reports

Sleep loss activates cellular inflammation and signal transducer and activator of transcription (STAT) family proteins in humans

(2015) Michael R. Irwin et al.   BRAIN BEHAVIOR AND IMMUNITY

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Sleep deprivation and hippocampal vulnerability: changes in neuronal plasticity, neurogenesis and cognitive function

(2015) J.C. Kreutzmann et al.   NEUROSCIENCE

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

Pro-inflammatory interleukin-18 increases Alzheimer’s disease-associated amyloid-β production in human neuron-like cells

(2012) Elina M Sutinen et al.   Journal of Neuroinflammation

Amyloid-  Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle

(2009) J.-E. Kang et al.   SCIENCE

Sleep Loss Activates Cellular Inflammatory Signaling

(2008) Michael R. Irwin et al.   BIOLOGICAL PSYCHIATRY

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice

(2008) P. D. Cani et al.   DIABETES