Pro-inflammatory interleukin-18 increases Alzheimer’s disease-associated amyloid-β production in human neuron-like cells

Inflammation in Alzheimer Disease--A Brief Review of the Basic Science and Clinical Literature

(2013) T. Wyss-Coray et al.   Cold Spring Harbor Perspectives in Medicine

APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP

(2011) Sascha W Weyer et al.   EMBO JOURNAL

Soluble Amyloid Precursor Protein Induces Rapid Neural Differentiation of Human Embryonic Stem Cells

(2011) Kristine K. Freude et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional and Topological Analysis of Pen-2, the Fourth Subunit of the γ-Secretase Complex

(2011) Leen Bammens et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Presenilin-1 Regulates Neural Progenitor Cell Differentiation in the Adult Brain

(2011) A. Gadadhar et al.   JOURNAL OF NEUROSCIENCE

Effect of glycogen synthase kinase 3 β-mediated presenilin 1 phosphorylation on amyloid β production is negatively regulated by insulin receptor cleavage

(2011) M. Maesako et al.   NEUROSCIENCE

Presenilins: how much more than γ-secretase?!

(2010) Katrijn Coen et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Interleukin 18 in the CNS

(2010) Silvia Alboni et al.   Journal of Neuroinflammation

The Inflammasome Sensor, NLRP3, Regulates CNS Inflammation and Demyelination via Caspase-1 and Interleukin-18

(2010) S. Jha et al.   JOURNAL OF NEUROSCIENCE

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Interleukin-18 regulates motor activity, anxiety and spatial learning without affecting synaptic plasticity

(2009) Takahiro Yaguchi et al.   BEHAVIOURAL BRAIN RESEARCH

Differentiation of Human SH-SY5Y Neuroblastoma Cells by All-Trans Retinoic Acid Activates the Interleukin-18 System

(2009) Hannes Sallmon et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

(2009) Anatoly Nikolaev et al.   NATURE

Interleukin-18 promoter polymorphisms and risk of late onset Alzheimer's disease

(2008) Jin-Tai Yu et al.   BRAIN RESEARCH

Activity requires soluble amyloid precursor protein α to promote neurite outgrowth in neural stem cell-derived neurons via activation of the MAPK pathway

(2008) Nidhi Gakhar-Koppole et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Building γ-secretase – the bits and pieces

(2008) Dragana Spasic et al.   JOURNAL OF CELL SCIENCE

Interleukin-18 increases expression of kinases involved in tau phosphorylation in SH-SY5Y neuroblastoma cells

(2008) Johanna O. Ojala et al.   JOURNAL OF NEUROIMMUNOLOGY

Lack of association between Interleukin-18 gene promoter polymorphisms and onset of Alzheimer's disease

(2008) Ludovica Segat et al.   NEUROBIOLOGY OF AGING

Plasma amyloid levels and the risk of AD in normal subjects in the Cardiovascular Health Study

(2008) O. L. Lopez et al.   NEUROLOGY

Proteomic Profiling of γ-Secretase Substrates and Mapping of Substrate Requirements

(2008) Matthew L Hemming et al.   PLOS BIOLOGY

Interleukin-18 produced by peripheral blood cells is increased in Alzheimer’s disease and correlates with cognitive impairment

(2007) Paola Bossù et al.   BRAIN BEHAVIOR AND IMMUNITY

Interleukin-18 and stress

(2007) Shuei Sugama et al.   BRAIN RESEARCH REVIEWS

Amyloid β peptide promotes differentiation of pro-inflammatory human myeloid dendritic cells

(2007) Antonio Ciaramella et al.   NEUROBIOLOGY OF AGING

Expression of interleukin-18 is increased in the brains of Alzheimer's disease patients

(2007) Johanna Ojala et al.   NEUROBIOLOGY OF AGING