Gut microbiota from NLRP3-deficient mice ameliorates depressive-like behaviors by regulating astrocyte dysfunction via circHIPK2

Activation of P2X7 receptor and NLRP3 inflammasome assembly in hippocampal glial cells mediates chronic stress-induced depressive-like behaviors

(2017) Na Yue et al.   Journal of Neuroinflammation

Berberine Ameliorates Diabetes-Associated Cognitive Decline through Modulation of Aberrant Inflammation Response and Insulin Signaling Pathway in DM Rats

(2017) Qingjie Chen et al.   Frontiers in Pharmacology

Psychological Stress Activates the Inflammasome via Release of Adenosine Triphosphate and Stimulation of the Purinergic Type 2X7 Receptor

(2016) Masaaki Iwata et al.   BIOLOGICAL PSYCHIATRY

Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat

(2016) John R. Kelly et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Inflammasome signaling affects anxiety- and depressive-like behavior and gut microbiome composition

(2016) M-L Wong et al.   MOLECULAR PSYCHIATRY

Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host’s metabolism

(2016) P Zheng et al.   MOLECULAR PSYCHIATRY

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

(2016) Veit Rothhammer et al.   NATURE MEDICINE

Psychobiotics and the Manipulation of Bacteria–Gut–Brain Signals

(2016) Amar Sarkar et al.   TRENDS IN NEUROSCIENCES

Ly6Chi Monocytes Provide a Link between Antibiotic-Induced Changes in Gut Microbiota and Adult Hippocampal Neurogenesis

(2016) Luisa Möhle et al.   Cell Reports

Serotonin, tryptophan metabolism and the brain-gut-microbiome axis

(2015) S.M. O’Mahony et al.   BEHAVIOURAL BRAIN RESEARCH

Re: Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour

(2015) Lieve Desbonnet et al.   BRAIN BEHAVIOR AND IMMUNITY

Altered fecal microbiota composition in patients with major depressive disorder

(2015) Haiyin Jiang et al.   BRAIN BEHAVIOR AND IMMUNITY

Regulation of astrocyte pathology by fluoxetine prevents the deterioration of Alzheimer phenotypes in an APP/PS1 mouse model

(2015) Jinping Qiao et al.   GLIA

Gut Microbiota and Brain Function: An Evolving Field in Neuroscience: Table 1.

(2015) Jane A Foster et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2015) Theo Vos et al.   LANCET

Stress-Induced Depressive Behaviors Require a Functional NLRP3 Inflammasome

(2015) Elísabet Alcocer-Gómez et al.   MOLECULAR NEUROBIOLOGY

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Microglial NLRP3 inflammasome activation mediates IL-1β-related inflammation in prefrontal cortex of depressive rats

(2014) Ying Pan et al.   BRAIN BEHAVIOR AND IMMUNITY

Epigenetic Signaling in Psychiatric Disorders

(2014) Catherine J. Peña et al.   JOURNAL OF MOLECULAR BIOLOGY

The organization of the stress system and its dysregulation in depressive illness

(2014) P W Gold   MOLECULAR PSYCHIATRY

Correlation between the human fecal microbiota and depression

(2014) A. Naseribafrouei et al.   NEUROGASTROENTEROLOGY AND MOTILITY

NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder

(2013) Elísabet Alcocer-Gómez et al.   BRAIN BEHAVIOR AND IMMUNITY

Involvement of Inflammasome Activation in Lipopolysaccharide-induced Mice Depressive-like Behaviors

(2013) Yi Zhang et al.   CNS Neuroscience & Therapeutics

Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010

(2013) Harvey A Whiteford et al.   LANCET

Astrocyte-derived ATP modulates depressive-like behaviors

(2013) Xiong Cao et al.   NATURE MEDICINE

The gut microbiota — masters of host development and physiology

(2013) Felix Sommer et al.   NATURE REVIEWS MICROBIOLOGY

Altered colonic function and microbiota profile in a mouse model of chronic depression

(2013) A. J. Park et al.   NEUROGASTROENTEROLOGY AND MOTILITY

The inflammasome: Pathways linking psychological stress, depression, and systemic illnesses

(2012) Masaaki Iwata et al.   BRAIN BEHAVIOR AND IMMUNITY

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

(2012) John F. Cryan et al.   NATURE REVIEWS NEUROSCIENCE

Cross-national epidemiology of DSM-IV major depressive episode

(2011) Evelyn Bromet et al.   BMC Medicine

The Intestinal Microbiota Affect Central Levels of Brain-Derived Neurotropic Factor and Behavior in Mice

(2011) Premysl Bercik et al.   GASTROENTEROLOGY

Molecular evidence for BDNF- and GABA-related dysfunctions in the amygdala of female subjects with major depression

(2011) J-P Guilloux et al.   MOLECULAR PSYCHIATRY

Grand challenges in global mental health

(2011) Pamela Y. Collins et al.   NATURE

Bacterial infection causes stress-induced memory dysfunction in mice

(2010) M. G. Gareau et al.   GUT

The GABAergic deficit hypothesis of major depressive disorder

(2010) B Luscher et al.   MOLECULAR PSYCHIATRY

Fronto-cingulate effective connectivity in major depression: A study with fMRI and dynamic causal modeling

(2008) R.G.M. Schlösser et al.   NEUROIMAGE