标题
R-spondin family biology and emerging linkages to cancer
作者
关键词
-
出版物
ANNALS OF MEDICINE
Volume 55, Issue 1, Pages 428-446
出版商
Informa UK Limited
发表日期
2023-01-16
DOI
10.1080/07853890.2023.2166981
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Tumour mutational burden: an overview for pathologists
- (2022) Kenneth D. Doig et al. PATHOLOGY
- Comprehensive Analysis of R-Spondin Fusions and RNF43 Mutations Implicate Novel Therapeutic Options in Colorectal Cancer
- (2022) Andreas Seeber et al. CLINICAL CANCER RESEARCH
- Tumor Microenvironment-Derived R-spondins Enhance Anti-Tumor Immunity to Suppress Tumor Growth and Sensitize for Immune Checkpoint Blockade Therapy
- (2021) Yuting Tang et al. Cancer Discovery
- RSPO2 inhibits BMP signaling to promote self-renewal in acute myeloid leukemia
- (2021) Rui Sun et al. Cell Reports
- The role of R-spondin proteins in cancer biology
- (2021) Eline J. ter Steege et al. ONCOGENE
- R-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth
- (2020) Marie-Cécile De Cian et al. CELL DEATH AND DIFFERENTIATION
- R-spondin-mediated WNT signaling potentiation in mammary and breast cancer development
- (2020) Johanna M. Tocci et al. IUBMB LIFE
- Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organs
- (2020) Mingjun Zhang et al. PLoS One
- R-spondin2 Suppresses the Progression of Hepatocellular Carcinoma via MAPK Signaling Pathway
- (2020) Chang Zheng et al. MOLECULAR CANCER RESEARCH
- R-Spondin 2 Induces Odontogenic Differentiation of Dental Pulp Stem/Progenitor Cells via Regulation of Wnt/β-Catenin Signaling
- (2020) Yuping Gong et al. Frontiers in Physiology
- R-Spondin 1 (RSPO1) Increases Mouse Intestinal Organoid Unit Size and Survival in vitro and Improves Tissue-Engineered Small Intestine Formation in vivo
- (2020) Gabriel Levin et al. Frontiers in Bioengineering and Biotechnology
- Phase 1 study of CWP232291 in patients with relapsed or refractory acute myeloid leukemia and myelodysplastic syndrome
- (2020) Je-Hwan Lee et al. Blood Advances
- LGR5 constitutively activates NF‐κB signaling to regulate the growth of intestinal crypts
- (2020) Shanshan Lai et al. FASEB JOURNAL
- Expression of R-spondin1 in Apc Mice Reduces Growth of Intestinal Adenomas by Altering Wnt and TGFB Signaling
- (2020) Marianne Lähde et al. GASTROENTEROLOGY
- Targeting the Wnt/β-catenin signaling pathway in cancer
- (2020) Ya Zhang et al. Journal of Hematology & Oncology
- Understanding the role of the R-spondin 2-LGR4 system in tongue squamous cell carcinoma progression
- (2019) Ahmed Al-Samadi et al. EBioMedicine
- R-spondin 2-LGR4 system regulates growth, migration and invasion, epithelial-mesenchymal transition and stem-like properties of tongue squamous cell carcinoma via Wnt/β-catenin signaling
- (2019) Liping Zhang et al. EBioMedicine
- R-spondin-3 induces secretory, antimicrobial Lgr5+ cells in the stomach
- (2019) Michael Sigal et al. NATURE CELL BIOLOGY
- R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon
- (2019) Christine Harnack et al. Nature Communications
- R-Spondin3 promotes the tumor growth of choriocarcinoma JEG-3 cells
- (2019) Zhilong Chen et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- R-Spondin-2 Is Upregulated in Idiopathic Pulmonary Fibrosis and Affects Fibroblast Behavior
- (2018) Adrián Munguía-Reyes et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- R-spondin3-LGR4 signaling protects hepatocytes against DMOG-induced hypoxia/reoxygenation injury through activating β-catenin
- (2018) Shiying Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- In silico discovery of quinoxaline derivatives as novel LRP5/6-sclerostin interaction inhibitors
- (2018) Jiwon Choi et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Gigantol inhibits Wnt/β-catenin signaling and exhibits anticancer activity in breast cancer cells
- (2018) Shubin Yu et al. BMC Complementary and Alternative Medicine
- Targeting the Wnt/beta-catenin pathway in cancer: Update on effectors and inhibitors
- (2018) Nithya Krishnamurthy et al. CANCER TREATMENT REVIEWS
- PDGFRα+pericryptal stromal cells are the critical source of Wnts and RSPO3 for murine intestinal stem cells in vivo
- (2018) Gediminas Greicius et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- R-spondins can potentiate WNT signaling without LGRs
- (2018) Andres M Lebensohn et al. eLife
- The role of R-spondin 1 through activating Wnt/β-catenin in the growth, survival and migration of ovarian cancer cells
- (2018) Qiong Liu et al. GENE
- Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal
- (2017) Kelley S. Yan et al. NATURE
- RSPO3 antagonism inhibits growth and tumorigenicity in colorectal tumors harboring common Wnt pathway mutations
- (2017) Marcus M. Fischer et al. Scientific Reports
- RSPO3-LGR4 Regulates Osteogenic Differentiation Of Human Adipose-Derived Stem Cells Via ERK/FGF Signalling
- (2017) Min Zhang et al. Scientific Reports
- Endothelial RSPO3 Controls Vascular Stability and Pruning through Non-canonical WNT/Ca 2+ /NFAT Signaling
- (2016) Beate Scholz et al. DEVELOPMENTAL CELL
- C-mannosylation of R-spondin3 regulates its secretion and activity of Wnt/β-catenin signaling in cells
- (2016) Miho Fujiwara et al. FEBS LETTERS
- Control of Wnt Receptor Turnover by R-spondin-ZNRF3/RNF43 Signaling Module and Its Dysregulation in Cancer
- (2016) Huai-Xiang Hao et al. Cancers
- R-Spondin 1/Dickkopf-1/Beta-Catenin Machinery Is Involved in Testicular Embryonic Angiogenesis
- (2015) Maria Caruso et al. PLoS One
- R-Spondin 3 Regulates Dorsoventral and Anteroposterior Patterning by Antagonizing Wnt/β-Catenin Signaling in Zebrafish Embryos
- (2014) Xiaozhi Rong et al. PLoS One
- Regulation of the Follistatin Gene by RSPO-LGR4 Signaling via Activation of the WNT/ -Catenin Pathway in Skeletal Myogenesis
- (2013) X. H. Han et al. MOLECULAR AND CELLULAR BIOLOGY
- Nimbolide, a neem limonoid abrogates canonical NF-κB and Wnt signaling to induce caspase-dependent apoptosis in human hepatocarcinoma (HepG2) cells
- (2012) Krishnamurthy Kavitha et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Recurrent R-spondin fusions in colon cancer
- (2012) Somasekar Seshagiri et al. NATURE
- ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner
- (2012) Huai-Xiang Hao et al. NATURE
- Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors
- (2012) A. Gurney et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The R-spondin protein family
- (2012) Wim BM de Lau et al. GENOME BIOLOGY
- Rspo3 Binds Syndecan 4 and Induces Wnt/PCP Signaling via Clathrin-Mediated Endocytosis to Promote Morphogenesis
- (2011) Bisei Ohkawara et al. DEVELOPMENTAL CELL
- LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling
- (2011) Andrei Glinka et al. EMBO REPORTS
- A WNT/β-Catenin Signaling Activator, R-spondin, Plays Positive Regulatory Roles during Skeletal Myogenesis
- (2011) Xiang Hua Han et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling
- (2011) Wim de Lau et al. NATURE
- Molecular analysis shows differential expression of R-spondin1 in zebrafish (Danio rerio) gonads
- (2010) Yanmei Zhang et al. MOLECULAR BIOLOGY REPORTS
- Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α
- (2010) Curtis A Thorne et al. Nature Chemical Biology
- Thrombospondins and Novel TSR-containing Proteins, R-spondins, Regulate Bone Formation and Remodeling
- (2010) Kurt D. Hankenson et al. Current Osteoporosis Reports
- Loss-of-function point mutations and two-furin domain derivatives provide insights about R-spondin2 structure and function
- (2009) Sheng-Jian Li et al. CELLULAR SIGNALLING
- R-Spondin1 protects mice from chemotherapy or radiation-induced oral mucositis through the canonical Wnt/ -catenin pathway
- (2009) J. Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- R-spondin1 and FOXL2 act into two distinct cellular types during goat ovarian differentiation
- (2008) Ayhan Kocer et al. BMC DEVELOPMENTAL BIOLOGY
- Cloning and expression of R-Spondin1 in different vertebrates suggests a conserved role in ovarian development
- (2008) Craig A Smith et al. BMC DEVELOPMENTAL BIOLOGY
- The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development
- (2008) O. Kazanskaya et al. DEVELOPMENT
- R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis
- (2008) S. M. Bell et al. DEVELOPMENT
- R-spondin1 plays an essential role in ovarian development through positively regulating Wnt-4 signaling
- (2008) Kazuma Tomizuka et al. HUMAN MOLECULAR GENETICS
- R-Spondin Family Members Regulate the Wnt Pathway by a Common Mechanism
- (2008) Kyung-Ah Kim et al. MOLECULAR BIOLOGY OF THE CELL
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started