PDGFRα+pericryptal stromal cells are the critical source of Wnts and RSPO3 for murine intestinal stem cells in vivo
出版年份 2018 全文链接
标题
PDGFRα+pericryptal stromal cells are the critical source of Wnts and RSPO3 for murine intestinal stem cells in vivo
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 115, Issue 14, Pages E3173-E3181
出版商
Proceedings of the National Academy of Sciences
发表日期
2018-03-21
DOI
10.1073/pnas.1713510115
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal
- (2017) Kelley S. Yan et al. NATURE
- CD34+mesenchymal cells are a major component of the intestinal stem cells niche at homeostasis and after injury
- (2017) Igor Stzepourginski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Telocytes heterogeneity: From cellular morphology to functional evidence
- (2017) Dragos Cretoiu et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- R-Spondins Are Expressed by the Intestinal Stroma and are Differentially Regulated during Citrobacter rodentium- and DSS-Induced Colitis in Mice
- (2016) Eugene Kang et al. PLoS One
- Wnts are dispensable for differentiation and self-renewal of adult murine hematopoietic stem cells
- (2015) Z. Kabiri et al. BLOOD
- Therapeutic Targeting of Tumor-Derived R-Spondin Attenuates -Catenin Signaling and Tumorigenesis in Multiple Cancer Types
- (2015) C. Chartier et al. CANCER RESEARCH
- Integrative Clinical Genomics of Advanced Prostate Cancer
- (2015) Dan Robinson et al. CELL
- Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function
- (2015) Elaine E. Storm et al. NATURE
- Filopodia-based Wnt transport during vertebrate tissue patterning
- (2015) Eliana Stanganello et al. Nature Communications
- Dose-Response Analysis Using R
- (2015) Christian Ritz et al. PLoS One
- Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts
- (2014) Z. Kabiri et al. DEVELOPMENT
- The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength
- (2014) W. de Lau et al. GENES & DEVELOPMENT
- Telocytes express PDGFRα in the human gastrointestinal tract
- (2014) Maria-Giuliana Vannucchi et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Wnt Secretion from Epithelial Cells and Subepithelial Myofibroblasts Is Not Required in the Mouse Intestinal Stem Cell Niche In Vivo
- (2014) Adrianna K. San Roman et al. Stem Cell Reports
- A novel population of subepithelial platelet-derived growth factor receptor α-positive cells in the mouse and human colon
- (2013) Masaaki Kurahashi et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Reconstitution of R-Spondin:LGR4:ZNRF3 Adult Stem Cell Growth Factor Signaling Complexes with Recombinant Proteins Produced in Escherichia coli
- (2013) Heather E. Moad et al. BIOCHEMISTRY
- The Intestinal Crypt, A Prototype Stem Cell Compartment
- (2013) Hans Clevers CELL
- Porcn-dependent Wnt signaling is not required prior to mouse gastrulation
- (2013) S. Biechele et al. DEVELOPMENT
- Interaction with both ZNRF3 and LGR4 is required for the signalling activity of R-spondin
- (2013) Yang Xie et al. EMBO REPORTS
- Lgr4Gene Deficiency Increases Susceptibility and Severity of Dextran Sodium Sulfate-induced Inflammatory Bowel Disease in Mice
- (2013) Shijie Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- In vitro expansion and genetic modification of gastrointestinal stem cells in spheroid culture
- (2013) Hiroyuki Miyoshi et al. Nature Protocols
- Canonical Wnt/β-catenin Signaling Drives Human Schwann Cell Transformation, Progression, and Tumor Maintenance
- (2013) Adrienne L. Watson et al. Cancer Discovery
- Optimality in the Development of Intestinal Crypts
- (2012) Shalev Itzkovitz et al. CELL
- Redundant Sources of Wnt Regulate Intestinal Stem Cells and Promote Formation of Paneth Cells
- (2012) Henner F. Farin et al. GASTROENTEROLOGY
- A conditional allele ofRspo3reveals redundant function of R-spondins during mouse limb development
- (2012) Stanley Neufeld et al. GENESIS
- Precise Regulation of Porcupine Activity Is Required for Physiological Wnt Signaling
- (2012) Kyle D. Proffitt et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Recurrent R-spondin fusions in colon cancer
- (2012) Somasekar Seshagiri et al. NATURE
- ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner
- (2012) Huai-Xiang Hao et al. NATURE
- LGR6 Is a High Affinity Receptor of R-Spondins and Potentially Functions as a Tumor Suppressor
- (2012) Xing Gong et al. PLoS One
- Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1)
- (2012) A. Durand et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells
- (2012) T.-H. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The R-spondin protein family
- (2012) Wim BM de Lau et al. GENOME BIOLOGY
- Intestinal myofibroblasts: targets for stem cell therapy
- (2011) R. C. Mifflin et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Ultrastructural and Immunohistochemical Analysis of Intestinal Myofibroblasts During the Early Organogenesis of the Human Small Intestine
- (2011) Rosa Artells et al. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
- A sensitive and bright single-cell resolution live imaging reporter of Wnt/ß-catenin signaling in the mouse
- (2011) Anna Ferrer-Vaquer et al. BMC DEVELOPMENTAL BIOLOGY
- Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling
- (2011) Eric Festa et al. CELL
- Rspo3 Binds Syndecan 4 and Induces Wnt/PCP Signaling via Clathrin-Mediated Endocytosis to Promote Morphogenesis
- (2011) Bisei Ohkawara et al. DEVELOPMENTAL CELL
- WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification
- (2010) G. S. Coombs et al. JOURNAL OF CELL SCIENCE
- Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
- (2009) Toshiro Sato et al. NATURE
- Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche
- (2009) Akifumi Ootani et al. NATURE MEDICINE
- The transcriptome of retinal Müller glial cells
- (2008) Karin Roesch et al. JOURNAL OF COMPARATIVE NEUROLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation