R-Spondin 3 Regulates Dorsoventral and Anteroposterior Patterning by Antagonizing Wnt/β-Catenin Signaling in Zebrafish Embryos

Interaction with both ZNRF3 and LGR4 is required for the signalling activity of R-spondin

(2013) Yang Xie et al.   EMBO REPORTS

A finger on the pulse of Wnt receptor signaling

(2012) Bryan T MacDonald et al.   CELL RESEARCH

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

(2012) Huai-Xiang Hao et al.   NATURE

R-Spondin Potentiates Wnt/β-Catenin Signaling through Orphan Receptors LGR4 and LGR5

(2012) Heinz Ruffner et al.   PLoS One

The Stress-Response Gene redd1 Regulates Dorsoventral Patterning by Antagonizing Wnt/β-catenin Activity in Zebrafish

(2012) Qiang Feng et al.   PLoS One

Wnt Signaling in Vertebrate Axis Specification

(2012) H. Hikasa et al.   Cold Spring Harbor Perspectives in Biology

The R-spondin protein family

(2012) Wim BM de Lau et al.   GENOME BIOLOGY

Maternal and Zygotic Control of Zebrafish Dorsoventral Axial Patterning

(2011) Yvette G. Langdon et al.   Annual Review of Genetics

Cellular signaling and biological functions of R-spondins

(2011) Jeong Kyo Yoon et al.   CELLULAR SIGNALLING

Waif1/5T4 Inhibits Wnt/β-Catenin Signaling and Activates Noncanonical Wnt Pathways by Modifying LRP6 Subcellular Localization

(2011) Birgit Kagermeier-Schenk et al.   DEVELOPMENTAL CELL

Rspo3 Binds Syndecan 4 and Induces Wnt/PCP Signaling via Clathrin-Mediated Endocytosis to Promote Morphogenesis

(2011) Bisei Ohkawara et al.   DEVELOPMENTAL CELL

LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling

(2011) Andrei Glinka et al.   EMBO REPORTS

Orphan receptors find a home

(2011) Walter Birchmeier   NATURE

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

(2011) Wim de Lau et al.   NATURE

Identification and mechanism of regulation of the zebrafish dorsal determinant

(2011) F.-I. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/ -catenin signaling

(2011) K. S. Carmon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A direct role for Wnt8 in ventrolateral mesoderm patterning

(2010) Kevin D. Baker et al.   DEVELOPMENTAL DYNAMICS

The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development

(2008) O. Kazanskaya et al.   DEVELOPMENT

R-Spondin Family Members Regulate the Wnt Pathway by a Common Mechanism

(2008) Kyung-Ah Kim et al.   MOLECULAR BIOLOGY OF THE CELL