A Narrative Review of STAT Proteins in Diabetic Retinopathy: From Mechanisms to Therapeutic Prospects
出版年份 2022 全文链接
标题
A Narrative Review of STAT Proteins in Diabetic Retinopathy: From Mechanisms to Therapeutic Prospects
作者
关键词
-
出版物
Ophthalmology and Therapy
Volume 11, Issue 6, Pages 2005-2026
出版商
Springer Science and Business Media LLC
发表日期
2022-10-08
DOI
10.1007/s40123-022-00581-0
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Role of Curcumin in Retinal Diseases—A review
- (2022) Priya R. Chandrasekaran et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Role of the JAK/STAT pathway in a streptozotocin-induced diabetic retinopathy mouse model
- (2022) Chan-Ho Cho et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- MG53 represses high glucose-induced inflammation and angiogenesis in human retinal endothelial cells by repressing the EGR1/STAT3 axis
- (2022) Kun-ming Cui et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Graphene quantum dots rescue angiogenic retinopathy via blocking STAT3/Periostin/ERK signaling
- (2022) Na Zhao et al. JOURNAL OF NANOBIOTECHNOLOGY
- Melatonin Maintains Inner Blood–Retinal Barrier by Regulating Microglia via Inhibition of PI3K/Akt/Stat3/NF-κB Signaling Pathways in Experimental Diabetic Retinopathy
- (2022) Lei Tang et al. Frontiers in Immunology
- STAT3 activation in microglia increases pericyte apoptosis in diabetic retinas through TNF-ɑ/AKT/p70S6 kinase signaling
- (2022) Jang-Hyuk Yun et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- STAT1 is essential for HSC function and maintains MHCIIhi stem cells that resists myeloablation and neoplastic expansion
- (2022) Juan Li et al. BLOOD
- A Mechanistic Exploratory Study on the Therapeutic Efficacy of Astragaloside IV Against Diabetic Retinopathy Revealed by Network Pharmacology
- (2022) Zhi-Hao Zhao et al. Frontiers in Pharmacology
- The phase changes of M1/M2 phenotype of microglia/macrophage following oxygen-induced retinopathy in mice
- (2021) Jia Li et al. INFLAMMATION RESEARCH
- The innate immune system in diabetic retinopathy
- (2021) Warren W. Pan et al. PROGRESS IN RETINAL AND EYE RESEARCH
- TPTEP1 suppresses high glucose-induced dysfunction in retinal vascular endothelial cells by interacting with STAT3 and targeting VEGFA
- (2021) Xiaoping Sun et al. ACTA DIABETOLOGICA
- How curcumin affects hyperglycemia-induced optic nerve damage: A short review
- (2021) İzem Olcay Şahin JOURNAL OF CHEMICAL NEUROANATOMY
- Neurovascular unit in diabetic retinopathy: pathophysiological roles and potential therapeutical targets
- (2021) Shen Nian et al. Eye and Vision
- A comprehensive review on the phytochemistry, pharmacokinetics, and antidiabetic effect of Ginseng
- (2021) Yage Liu et al. PHYTOMEDICINE
- Lutein as a Modulator of Oxidative Stress-Mediated Inflammatory Diseases
- (2021) Yu Jin Ahn et al. Antioxidants
- Tofacitinib Ameliorates Retinal Vascular Leakage in a Murine Model of Diabetic Retinopathy with Type 2 Diabetes
- (2021) Eimear M. Byrne et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- CircZNF532 knockdown protects retinal pigment epithelial cells against high glucose‐induced apoptosis and pyroptosis by regulating the miR‐20b‐5p/STAT3 axis
- (2021) Gao‐Hua Liang et al. Journal of Diabetes Investigation
- The role of JAK/STAT signaling pathway and its inhibitors in diseases
- (2020) Ping Xin et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Regulation of the miR-19b-mediated SOCS6-JAK2/STAT3 pathway by lncRNA MEG3 is involved in high glucose-induced apoptosis in hRMECs
- (2020) Fan Xiao et al. BIOSCIENCE REPORTS
- The potential of JAK/STAT pathway inhibition by ruxolitinib in the treatment of COVID-19
- (2020) Bakiye Goker Bagca et al. CYTOKINE & GROWTH FACTOR REVIEWS
- microRNA-216a protects against human retinal microvascular endothelial cell injury in diabetic retinopathy by suppressing the NOS2/JAK/STAT axis
- (2020) Yong Liu et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- PKM2 promotes Th17 cell differentiation and autoimmune inflammation by fine-tuning STAT3 activation
- (2020) Luis Eduardo Alves Damasceno et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A STAT3 palmitoylation cycle promotes TH17 differentiation and colitis
- (2020) Mingming Zhang et al. NATURE
- Ocular surface diabetic disease: A neurogenic condition?
- (2020) Antonio Di Zazzo et al. Ocular Surface
- Stat2-Drp1 mediated mitochondrial mass increase is necessary for pro-inflammatory differentiation of macrophages
- (2020) Weihua Yu et al. Redox Biology
- Human umbilical cord mesenchymal stem cells-derived exosomal microRNA-17-3p ameliorates inflammatory reaction and antioxidant injury of mice with diabetic retinopathy via targeting STAT1
- (2020) Wei Li et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Bioinformatic Reconstruction and Analysis of Gene Networks Related to Glucose Variability in Diabetes and Its Complications
- (2020) Olga V. Saik et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- STAT1 signaling shields T cells from NK cell-mediated cytotoxicity
- (2019) Yu Hui Kang et al. Nature Communications
- STAT3beta, a distinct isoform from STAT3
- (2019) Hui-Xiang Zhang et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- STAT3 activation in circulating myeloid-derived cells contributes to retinal microvascular dysfunction in diabetes
- (2019) Mei Chen et al. Journal of Neuroinflammation
- WITHDRAWN: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9th edition
- (2019) Pouya Saeedi et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Angiopoietin-Like Protein 4 (ANGPTL4) Induces Retinal Pigment Epithelial Barrier Breakdown by Activating Signal Transducer and Activator of Transcription 3 (STAT3): Evidence from ARPE-19 Cells Under Hypoxic Condition and Diabetic Rats
- (2019) Xinyue Yang et al. MEDICAL SCIENCE MONITOR
- Angiopoietin 1 attenuates interleukin-6-induced endothelial cell permeability through SHP-1
- (2019) Jang-Hyuk Yun et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Distinct downstream signaling and the roles of VEGF and PlGF in high glucose-mediated injuries of human retinal endothelial cells in culture
- (2019) Wanzhen Jiao et al. Scientific Reports
- A novel transthyretin/STAT4/miR-223-3p/FBXW7 signaling pathway affects neovascularization in diabetic retinopathy
- (2019) Jun Shao et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- FBXW7-mediated stability regulation of signal transducer and activator of transcription 2 in melanoma formation
- (2019) Cheol-Jung Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gene therapy knockdown of VEGFR2 in retinal endothelial cells to treat retinopathy
- (2018) Aaron B. Simmons et al. ANGIOGENESIS
- JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance
- (2018) Tianyi Wang et al. Cell Metabolism
- Role of Inflammation in Diabetic Retinopathy
- (2018) Anne Rübsam et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Role of Microglia in Diabetic Retinopathy: Inflammation, Microvasculature Defects and Neurodegeneration
- (2018) et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Targeting the IL-6/JAK/STAT3 signalling axis in cancer
- (2018) Daniel E. Johnson et al. Nature Reviews Clinical Oncology
- Structural basis of STAT2 recognition by IRF9 reveals molecular insights into ISGF3 function
- (2018) Srinivasan Rengachari et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- JAK/STAT – Emerging Players in Metabolism
- (2018) David W. Dodington et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Inhibition of interleukin-6 trans-signaling prevents inflammation and endothelial barrier disruption in retinal endothelial cells
- (2018) Maria L. Valle et al. EXPERIMENTAL EYE RESEARCH
- Interaction between microglia and retinal pigment epithelial cells determines the integrity of outer blood-retinal barrier in diabetic retinopathy
- (2018) Dong Hyun Jo et al. GLIA
- Wnt Signaling in vascular eye diseases
- (2018) Zhongxiao Wang et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Decursin and decursinol angelate: molecular mechanism and therapeutic potential in inflammatory diseases
- (2017) Adeeb Shehzad et al. INFLAMMATION RESEARCH
- miR-146a suppresses STAT3/VEGF pathways and reduces apoptosis through IL-6 signaling in primary human retinal microvascular endothelial cells in high glucose conditions
- (2017) Eun-Ah Ye et al. VISION RESEARCH
- HuoXueJieDu Formula Alleviates Diabetic Retinopathy in Rats by Inhibiting SOCS3-STAT3 and TIMP1-A2M Pathways
- (2017) Hongliang Wang et al. International Journal of Genomics
- Tang Wang Ming Mu Granule Attenuates Diabetic Retinopathy in Type 2 Diabetes Rats
- (2017) Mingxia Chen et al. Frontiers in Physiology
- Adipocyte STAT5 deficiency promotes adiposity and impairs lipid mobilisation in mice
- (2016) Doris Kaltenecker et al. DIABETOLOGIA
- Anti-inflammatory effect of topical administration of tofacitinib on corneal inflammation
- (2016) Tohru Sakimoto et al. EXPERIMENTAL EYE RESEARCH
- Novel STAT 3 inhibitors for treating gastric cancer
- (2016) Catherine Cafferkey et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- The JAK/STAT pathway in obesity and diabetes
- (2016) Esteban N. Gurzov et al. FEBS Journal
- Angiogenesis and Inflammation Crosstalk in Diabetic Retinopathy
- (2016) Margarida Capitão et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Endothelial STAT3 Activation Increases Vascular Leakage Through Downregulating Tight Junction Proteins: Implications for Diabetic Retinopathy
- (2016) Jang-Hyuk Yun et al. JOURNAL OF CELLULAR PHYSIOLOGY
- A STAT inhibitor patent review: progress since 2011
- (2015) Ping-Shan Lai et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- A Conserved Motif in the Linker Domain of STAT1 Transcription Factor Is Required for Both Recognition and Release from High-Affinity DNA-Binding Sites
- (2014) Bettina Hüntelmann et al. PLoS One
- Toward a new STATe: The role of STATs in mitochondrial function
- (2014) Jeremy A. Meier et al. SEMINARS IN IMMUNOLOGY
- STAT1-mediated Bim expression promotes the apoptosis of retinal pericytes under high glucose conditions
- (2014) E S Shin et al. Cell Death & Disease
- Therapeutic modulators of STAT signalling for human diseases
- (2013) Gabriella Miklossy et al. NATURE REVIEWS DRUG DISCOVERY
- Molecular Pathways: Interferon/Stat1 Pathway: Role in the Tumor Resistance to Genotoxic Stress and Aggressive Growth
- (2012) N. N. Khodarev et al. CLINICAL CANCER RESEARCH
- Protective Effects of Rosiglitazone on Retinal Neuronal Damage in Diabetic Rats
- (2012) Peiyu Li et al. CURRENT EYE RESEARCH
- Activating transcription factor 4 mediates hyperglycaemia-induced endothelial inflammation and retinal vascular leakage through activation of STAT3 in a mouse model of type 1 diabetes
- (2012) Y. Chen et al. DIABETOLOGIA
- Elevated histone acetylations in Müller cell contribute to inflammation: A novel inhibitory effect of minocycline
- (2012) Lei-Lei Wang et al. GLIA
- SOCS3 Deficiency Promotes M1 Macrophage Polarization and Inflammation
- (2012) H. Qin et al. JOURNAL OF IMMUNOLOGY
- Diabetic Retinopathy
- (2012) David A. Antonetti et al. NEW ENGLAND JOURNAL OF MEDICINE
- STAT5 isoforms regulate colorectal cancer cell apoptosis via reduction of mitochondrial membrane potential and generation of reactive oxygen species
- (2011) Wan Du et al. JOURNAL OF CELLULAR PHYSIOLOGY
- How to overcome retinal neuropathy: The fight against angiogenesisrelated blindness
- (2010) Dong Hyun Jo et al. ARCHIVES OF PHARMACAL RESEARCH
- Inhibition of Reactive Oxygen Species by Lovastatin Downregulates Vascular Endothelial Growth Factor Expression and Ameliorates Blood-Retinal Barrier Breakdown in db/db Mice: Role of NADPH Oxidase 4
- (2010) J. Li et al. DIABETES
- Blood-Retinal Barrier
- (2010) José Cunha-Vaz et al. EUROPEAN JOURNAL OF OPHTHALMOLOGY
- Disease candidate gene identification and prioritization using protein interaction networks
- (2009) Jing Chen et al. BMC BIOINFORMATICS
- Enalapril Alters Expression of Key Growth Factors in Experimental Diabetic Retinopathy
- (2009) Hyun Woong Kim et al. CURRENT EYE RESEARCH
- Interferon γ Attenuates Insulin Signaling, Lipid Storage, and Differentiation in Human Adipocytes via Activation of the JAK/STAT Pathway
- (2009) Fiona C. McGillicuddy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of transcription factor STAT5b suppresses proliferation, induces G1 cell cycle arrest and reduces tumor cell invasion in human glioblastoma multiforme cells
- (2008) Qin-Chuan Liang et al. CANCER LETTERS
- Diabetic Retinopathy
- (2008) Z. T. Bloomgarden DIABETES CARE
- Blood–retinal barrier in hypoxic ischaemic conditions: Basic concepts, clinical features and management
- (2008) C KAUR et al. PROGRESS IN RETINAL AND EYE RESEARCH
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