Melatonin Maintains Inner Blood–Retinal Barrier by Regulating Microglia via Inhibition of PI3K/Akt/Stat3/NF-κB Signaling Pathways in Experimental Diabetic Retinopathy

The phase changes of M1/M2 phenotype of microglia/macrophage following oxygen-induced retinopathy in mice

(2021) Jia Li et al.   INFLAMMATION RESEARCH

Intravitreal Delivery of Melatonin Is Protective Against the Photoreceptor Loss in Mice: A Potential Therapeutic Strategy for Degenerative Retinopathy

(2020) Chong Li et al.   Frontiers in Pharmacology

Erythropoietin protects the inner blood–retinal barrier by inhibiting microglia phagocytosis via Src/Akt/cofilin signalling in experimental diabetic retinopathy

(2020) Hai Xie et al.   DIABETOLOGIA

Targeting Host Defense System and Rescuing Compromised Mitochondria to Increase Tolerance against Pathogens by Melatonin May Impact Outcome of Deadly Virus Infection Pertinent to COVID-19

(2020) Dun-Xian Tan et al.   MOLECULES

Protective effect of melatonin in the diabetic rat retina

(2018) Saeed Mehrzadi et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

The Role of Microglia in Diabetic Retinopathy: Inflammation, Microvasculature Defects and Neurodegeneration

(2018) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Diabetic retinopathy pathogenesis and the ameliorating effects of melatonin; involvement of autophagy, inflammation and oxidative stress

(2018) Ehsan Dehdashtian et al.   LIFE SCIENCES

Microglia inhibit photoreceptor cell death and regulate immune cell infiltration in response to retinal detachment

(2018) Yoko Okunuki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retinal microglia – A key player in healthy and diseased retina

(2018) Gurugirijha Rathnasamy et al.   PROGRESS IN NEUROBIOLOGY

Retinal vasculature development in health and disease

(2018) Senthil Selvam et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Microglia enhanced the angiogenesis, migration and proliferation of co-cultured RMECs

(2018) Xinyi Ding et al.   BMC Ophthalmology

Retinal Diseases Associated with Oxidative Stress and the Effects of a Free Radical Scavenger (Edaravone)

(2017) Tomomi Masuda et al.   Oxidative Medicine and Cellular Longevity

Modulation of microglia polarization dynamics during diabetic retinopathy in db / db mice

(2016) Ana I. Arroba et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Melatonin synergistically enhances protective effect of atorvastatin against gentamicin-induced nephrotoxicity in rat kidney

(2016) Saeed Mehrzadi et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

The “Big-Bang” for modern glial biology: Translation and comments on Pío del Río-Hortega 1919 series of papers on microglia

(2016) Amanda Sierra et al.   GLIA

Protective Effects of Melatonin on Retinal Inflammation and Oxidative Stress in Experimental Diabetic Retinopathy

(2016) Tingting Jiang et al.   Oxidative Medicine and Cellular Longevity

pEPito-drivenPEDFExpression Ameliorates Diabetic Retinopathy Hallmarks

(2016) Sofia M. Calado et al.   Human Gene Therapy Methods

Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration

(2015) L. Zhao et al.   EMBO Molecular Medicine

Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization

(2015) Abhishek K. Jha et al.   IMMUNITY

Melatonin: an ancient molecule that makes oxygen metabolically tolerable

(2015) Lucien C. Manchester et al.   JOURNAL OF PINEAL RESEARCH

Contribution of Microglia-Mediated Neuroinflammation to Retinal Degenerative Diseases

(2015) Maria H. Madeira et al.   MEDIATORS OF INFLAMMATION

Exploring the various aspects of the pathological role of vascular endothelial growth factor (VEGF) in diabetic retinopathy

(2015) Tapan Behl et al.   PHARMACOLOGICAL RESEARCH

Delivery of pineal melatonin to the brain and SCN: role of canaliculi, cerebrospinal fluid, tanycytes and Virchow–Robin perivascular spaces

(2014) Russel J. Reiter et al.   Brain Structure & Function

Qingkailing Suppresses the Activation of BV2 Microglial Cells by Inhibiting Hypoxia/Reoxygenation-Induced Inflammatory Responses

(2014) Lulu Mana et al.   Evidence-based Complementary and Alternative Medicine

Early spatiotemporal characterization of microglial activation in the retinas of rats with streptozotocin-induced diabetes

(2014) Xiaofei Chen et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Melatonin from Cerebrospinal Fluid but Not from Blood Reaches Sheep Cerebral Tissues Under Physiological Conditions

(2014) C. Legros et al.   JOURNAL OF NEUROENDOCRINOLOGY

Retinal Microglial Activation and Inflammation Induced by Amadori-Glycated Albumin in a Rat Model of Diabetes

(2011) A. S. Ibrahim et al.   DIABETES

Inflammation in diabetic retinopathy

(2011) Johnny Tang et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Microvascular lesions of diabetic retinopathy: clues towards understanding pathogenesis?

(2009) T M Curtis et al.   EYE