Rapamycin treatment during development extends life span and health span of male mice and Daphnia magna

Life histories of myeloproliferative neoplasms inferred from phylogenies

(2022) Nicholas Williams et al.   NATURE

A mammalian methylation array for profiling methylation levels at conserved sequences

(2022) Adriana Arneson et al.   Nature Communications

Genetic loci and metabolic states associated with murine epigenetic aging

(2022) Khyobeni Mozhui et al.   eLife

A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing

(2021) Yu-Xuan Lu et al.   eLife

Increased fidelity of protein synthesis extends lifespan

(2021) Victoria Eugenia Martinez-Miguel et al.   Cell Metabolism

Age and life expectancy clocks based on machine learning analysis of mouse frailty

(2020) Michael B. Schultz et al.   Nature Communications

Identification and Application of Gene Expression Signatures Associated with Lifespan Extension

(2019) Alexander Tyshkovskiy et al.   Cell Metabolism

Royal Jelly and Its Components Promote Healthy Aging and Longevity: From Animal Models to Humans

(2019) Kunugi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Developmental ROS individualizes organismal stress resistance and lifespan

(2019) Daphne Bazopoulou et al.   NATURE

Signaling Pathways Involved in the Regulation of mRNA Translation

(2018) Philippe P. Roux et al.   MOLECULAR AND CELLULAR BIOLOGY

Effects of rapamycin on growth hormone receptor knockout mice

(2018) Yimin Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitohormesis in Mice via Sustained Basal Activation of Mitochondrial and Antioxidant Signaling

(2018) Carly S. Cox et al.   Cell Metabolism

Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions

(2018) Eugenio F. Fornasiero et al.   Nature Communications

Low-dose rapamycin extends lifespan in a mouse model of mtDNA depletion syndrome

(2017) Stephanie E Siegmund et al.   HUMAN MOLECULAR GENETICS

Molecular signatures of longevity: Insights from cross-species comparative studies

(2017) Siming Ma et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Longevity is impacted by growth hormone action during early postnatal period

(2017) Liou Y Sun et al.   eLife

Longevity extension of worker honey bees (Apis mellifera) by royal jelly: optimal dose and active ingredient

(2017) Wenchao Yang et al.   PeerJ

A Frailty Index Based On Deficit Accumulation Quantifies Mortality Risk in Humans and in Mice

(2017) K. Rockwood et al.   Scientific Reports

Disruption of the GH Receptor Gene in Adult Mice Increases Maximal Lifespan in Females

(2016) Riia K. Junnila et al.   ENDOCRINOLOGY

Rapamycin up-regulates triglycerides in hepatocytes by down-regulating Prox1

(2016) Sora Kwon et al.   Lipids in Health and Disease

Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice

(2016) Alessandro Bitto et al.   eLife

Gene expression defines natural changes in mammalian lifespan

(2015) Alexey A. Fushan et al.   AGING CELL

Shorter Men Live Longer: Association of Height with Longevity and FOXO3 Genotype in American Men of Japanese Ancestry

(2014) Qimei He et al.   PLoS One

Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction

(2013) Richard A. Miller et al.   AGING CELL

Identification of Long-Lived Proteins Reveals Exceptional Stability of Essential Cellular Structures

(2013) Brandon H. Toyama et al.   CELL

Ageing: It’s a Dog’s Life

(2013) Colin Selman et al.   CURRENT BIOLOGY

Growth hormone-releasing hormone disruption extends lifespan and regulates response to caloric restriction in mice

(2013) Liou Y Sun et al.   eLife

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

(2012) Davis J. McCarthy et al.   NUCLEIC ACIDS RESEARCH

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in Humans

(2011) J. Guevara-Aguirre et al.   Science Translational Medicine

Chronic Rapamycin Treatment Causes Glucose Intolerance and Hyperlipidemia by Upregulating Hepatic Gluconeogenesis and Impairing Lipid Deposition in Adipose Tissue

(2010) V. P. Houde et al.   DIABETES

Embryo growth rates in birds and mammals

(2010) Robert E. Ricklefs   FUNCTIONAL ECOLOGY

Life-Span Extension in Mice by Preweaning Food Restriction and by Methionine Restriction in Middle Age

(2009) L. Sun et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

(2009) David E. Harrison et al.   NATURE

Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation

(2008) A. Y. Choo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA