Life histories of myeloproliferative neoplasms inferred from phylogenies

Reconstructing the Lineage Histories and Differentiation Trajectories of Individual Cancer Cells in Myeloproliferative Neoplasms

(2021) Debra Van Egeren et al.   Cell Stem Cell

Somatic mutation landscapes at single-molecule resolution

(2021) Federico Abascal et al.   NATURE

Lineage tracing of human development through somatic mutations

(2021) Michael Spencer Chapman et al.   NATURE

Antiviral treatment causes a unique mutational signature in cancers of transplantation recipients

(2021) Jurrian K. de Kanter et al.   Cell Stem Cell

Pan-cancer analysis of whole genomes

(2020)   NATURE

The evolutionary history of 2,658 cancers

(2020) Moritz Gerstung et al.   NATURE

Engraftment of rare, pathogenic donor hematopoietic mutations in unrelated hematopoietic stem cell transplantation

(2020) Wing Hing Wong et al.   Science Translational Medicine

The mutational landscape of normal human endometrial epithelium

(2020) Luiza Moore et al.   NATURE

The evolutionary dynamics and fitness landscape of clonal hematopoiesis

(2020) Caroline J. Watson et al.   SCIENCE

Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells

(2020) Erik L. Bao et al.   NATURE

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

(2020) Alexander G. Bick et al.   NATURE

Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing

(2020) Peter Ellis et al.   Nature Protocols

Somatic mutations and clonal dynamics in healthy and cirrhotic human liver

(2019) Simon F. Brunner et al.   NATURE

The landscape of somatic mutation in normal colorectal epithelial cells

(2019) Henry Lee-Six et al.   NATURE

PPM1D truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells

(2018) Josephine D. Kahn et al.   BLOOD

MPBoot: fast phylogenetic maximum parsimony tree inference and bootstrap approximation

(2018) Diep Thi Hoang et al.   BMC EVOLUTIONARY BIOLOGY

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal

(2018) Thomas J. Mitchell et al.   CELL

Prediction of acute myeloid leukaemia risk in healthy individuals

(2018) Sagi Abelson et al.   NATURE

Population dynamics of normal human blood inferred from somatic mutations

(2018) Henry Lee-Six et al.   NATURE

Age-related remodelling of oesophageal epithelia by mutated cancer drivers

(2018) Akira Yokoyama et al.   NATURE

Classification and Personalized Prognosis in Myeloproliferative Neoplasms

(2018) Jacob Grinfeld et al.   NEW ENGLAND JOURNAL OF MEDICINE

Somatic mutant clones colonize the human esophagus with age

(2018) Iñigo Martincorena et al.   SCIENCE

Somatic Mutations Reveal Lineage Relationships and Age-Related Mutagenesis in Human Hematopoiesis

(2018) Fernando G. Osorio et al.   Cell Reports

Stan: A Probabilistic Programming Language

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Genetic basis and molecular pathophysiology of classical myeloproliferative neoplasms

(2016) William Vainchenker et al.   BLOOD

Germ line variants predispose to both JAK2 V617F clonal hematopoiesis and myeloproliferative neoplasms

(2016) D. A. Hinds et al.   BLOOD

The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia

(2016) D. A. Arber et al.   BLOOD

Clonal history of a cord blood donor cell leukemia with prenatal somatic JAK2 V617F mutation

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JAK2V617F complete molecular remission in polycythemia vera/essential thrombocythemia patients treated with ruxolitinib

(2015) L. Pieri et al.   BLOOD

DNMT3A mutations occur early or late in patients with myeloproliferative neoplasms and mutation order influences phenotype

(2015) J. Nangalia et al.   HAEMATOLOGICA

Inflammation as a Driver of Clonal Evolution in Myeloproliferative Neoplasm

(2015) Angela G. Fleischman   MEDIATORS OF INFLAMMATION

Clock-like mutational processes in human somatic cells

(2015) Ludmil B Alexandrov et al.   NATURE GENETICS

Effect of Mutation Order on Myeloproliferative Neoplasms

(2015) Christina A. Ortmann et al.   NEW ENGLAND JOURNAL OF MEDICINE

High burden and pervasive positive selection of somatic mutations in normal human skin

(2015) I. Martincorena et al.   SCIENCE

DNMT3A mutations occur early or late in patients with myeloproliferative neoplasms and mutation order influences phenotype

(2015) J. Nangalia et al.   HAEMATOLOGICA

How common are myeloproliferative neoplasms? A systematic review and meta-analysis

(2014) Glen J. Titmarsh et al.   AMERICAN JOURNAL OF HEMATOLOGY

Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms

(2014) P. Lundberg et al.   BLOOD

Age-related mutations associated with clonal hematopoietic expansion and malignancies

(2014) Mingchao Xie et al.   NATURE MEDICINE

Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

(2014) Giulio Genovese et al.   NEW ENGLAND JOURNAL OF MEDICINE

Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes

(2014) Siddhartha Jaiswal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epidemiology of myeloproliferative neoplasms in the United States

(2013) Jyotsna Mehta et al.   LEUKEMIA & LYMPHOMA

Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2

(2013) J. Nangalia et al.   NEW ENGLAND JOURNAL OF MEDICINE

Quantitative modeling of chronic myeloid leukemia: insights from radiobiology

(2012) T. Radivoyevitch et al.   BLOOD

JAK2V617F homozygosity arises commonly and recurrently in PV and ET, but PV is characterized by expansion of a dominant homozygous subclone

(2012) A. L. Godfrey et al.   BLOOD

Diagnostic value ofJAK2V617F somatic mutation for myeloproliferative cancer in 49 488 individuals from the general population

(2012) Camilla Nielsen et al.   BRITISH JOURNAL OF HAEMATOLOGY

The Origin and Evolution of Mutations in Acute Myeloid Leukemia

(2012) John S. Welch et al.   CELL

Effects of the JAK2 mutation on the hematopoietic stem and progenitor compartment in human myeloproliferative neoplasms

(2011) S. Anand et al.   BLOOD

Allele-specific copy number analysis of tumors

(2010) P. Van Loo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pindel: a pattern growth approach to detect break points of large deletions and medium sized insertions from paired-end short reads

(2009) K. Ye et al.   BIOINFORMATICS

A common JAK2 haplotype confers susceptibility to myeloproliferative neoplasms

(2009) Damla Olcaydu et al.   NATURE GENETICS

Pegylated interferon-alfa-2a induces complete hematologic and molecular responses with low toxicity in polycythemia vera

(2008) J.-J. Kiladjian et al.   BLOOD