Binding of SEP-363856 within TAAR1 and the 5HT1A receptor: implications for the design of novel antipsychotic drugs
出版年份 2021 全文链接
标题
Binding of SEP-363856 within TAAR1 and the 5HT1A receptor: implications for the design of novel antipsychotic drugs
作者
关键词
-
出版物
MOLECULAR PSYCHIATRY
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-08-10
DOI
10.1038/s41380-021-01250-7
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Structural equilibrium underlying ligand-dependent activation of β2-adrenoreceptor
- (2020) Shunsuke Imai et al. Nature Chemical Biology
- Binding of clozapine to the GABAB receptor: clinical and structural insights
- (2020) Pramod C. Nair et al. MOLECULAR PSYCHIATRY
- A Non–D2-Receptor-Binding Drug for the Treatment of Schizophrenia
- (2020) Kenneth S. Koblan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Promising Evidence of Antipsychotic Efficacy without Dopamine D2-Receptor Binding
- (2020) Donald C. Goff NEW ENGLAND JOURNAL OF MEDICINE
- Heterogeneous parallelization and acceleration of molecular dynamics simulations in GROMACS
- (2020) Szilárd Páll et al. JOURNAL OF CHEMICAL PHYSICS
- Arginine-259 of UDP-glycosyltransferase 2B7 (UGT2B7) confers UDP-sugar selectivity
- (2020) Pramod C. Nair et al. MOLECULAR PHARMACOLOGY
- Trace Amine-Associated Receptor 1 (TAAR1): A new drug target for psychiatry?
- (2020) Seetal Dodd et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Predictors of Treatment-Resistant and Clozapine-Resistant Schizophrenia: A 12-Year Follow-up Study of First-Episode Schizophrenia-Spectrum Disorders
- (2020) Sherry Kit Wa Chan et al. SCHIZOPHRENIA BULLETIN
- SEP-363856, A NOVEL PSYCHOTROPIC AGENT WITH A UNIQUE, NON-D2 RECEPTOR MECHANISM OF ACTION
- (2019) Nina Dedic et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- SWISS-MODEL: homology modelling of protein structures and complexes
- (2018) Andrew Waterhouse et al. NUCLEIC ACIDS RESEARCH
- Trace Amines and Their Receptors
- (2018) Raul R. Gainetdinov et al. PHARMACOLOGICAL REVIEWS
- The Case for TAAR1 as a Modulator of Central Nervous System Function
- (2018) Grazia Rutigliano et al. Frontiers in Pharmacology
- Crystal structure of the human 5-HT1B serotonin receptor bound to an inverse agonist
- (2018) Wanchao Yin et al. Cell Discovery
- Ten-year follow up of patients with first-episode schizophrenia spectrum disorder from an early intervention service: Predictors of clinical remission and functional recovery
- (2018) Sherry Kit Wa Chan et al. SCHIZOPHRENIA RESEARCH
- Pharmacology of human trace amine-associated receptors: Therapeutic opportunities and challenges
- (2017) Mark D. Berry et al. PHARMACOLOGY & THERAPEUTICS
- Discovery and Characterization of 2-Aminooxazolines as Highly Potent, Selective, and Orally Active TAAR1 Agonists
- (2016) Guido Galley et al. ACS Medicinal Chemistry Letters
- Trace amine-associated receptor 1 activation silences GSK3β signaling of TAAR1 and D2R heteromers
- (2015) Anja Harmeier et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists
- (2015) Grazia Chiellini et al. JOURNAL OF MEDICINAL CHEMISTRY
- TAAR1 Modulates Cortical Glutamate NMDA Receptor Function
- (2015) Stefano Espinoza et al. NEUROPSYCHOPHARMACOLOGY
- 10-year outcome study of an early intervention program for psychosis compared with standard care service
- (2014) S. K. W. Chan et al. PSYCHOLOGICAL MEDICINE
- Treatments of Negative Symptoms in Schizophrenia: Meta-Analysis of 168 Randomized Placebo-Controlled Trials
- (2014) Paolo Fusar-Poli et al. SCHIZOPHRENIA BULLETIN
- Optimisation of imidazole compounds as selective TAAR1 agonists: Discovery of RO5073012
- (2012) Guido Galley et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Insights into the Structure and Pharmacology of the Human Trace Amine-Associated Receptor 1 (hTAAR1): Homology Modelling and Docking Studies
- (2012) Elena Cichero et al. Chemical Biology & Drug Design
- Pharmacological treatment of schizophrenia: a critical review of the pharmacology and clinical effects of current and future therapeutic agents
- (2012) S Miyamoto et al. MOLECULAR PSYCHIATRY
- A new perspective for schizophrenia: TAAR1 agonists reveal antipsychotic- and antidepressant-like activity, improve cognition and control body weight
- (2012) F G Revel et al. MOLECULAR PSYCHIATRY
- A Systematic Review and Meta-Analysis of Recovery in Schizophrenia
- (2012) E. Jaaskelainen et al. SCHIZOPHRENIA BULLETIN
- Functional Interaction between Trace Amine-Associated Receptor 1 and Dopamine D2 Receptor
- (2011) S. Espinoza et al. MOLECULAR PHARMACOLOGY
- TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity
- (2011) F. G. Revel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Comparative pharmacology of antipsychotics possessing combined dopamine D2 and serotonin 5-HT1A receptor properties
- (2011) Adrian Newman-Tancredi et al. PSYCHOPHARMACOLOGY
- Selective antagonists of mouse trace amine-associated receptor 1 (mTAAR1): Discovery of EPPTB (RO5212773)
- (2010) Henri Stalder et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Rethinking schizophrenia
- (2010) Thomas R. Insel NATURE
- Schizophrenia
- (2009) Jim van Os et al. LANCET
- Metabolic side effects of antipsychotic drug treatment – pharmacological mechanisms
- (2009) Gavin P Reynolds et al. PHARMACOLOGY & THERAPEUTICS
- The Dopamine Hypothesis of Schizophrenia: Version III--The Final Common Pathway
- (2009) O. D. Howes et al. SCHIZOPHRENIA BULLETIN
- Akt/GSK3 Signaling in the Action of Psychotropic Drugs
- (2008) Jean-Martin Beaulieu et al. Annual Review of Pharmacology and Toxicology
- Schizophrenia: A Concise Overview of Incidence, Prevalence, and Mortality
- (2008) J. McGrath et al. EPIDEMIOLOGIC REVIEWS
- How effective are second-generation antipsychotic drugs? A meta-analysis of placebo-controlled trials
- (2008) S Leucht et al. MOLECULAR PSYCHIATRY
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