TAAR1 dependent and independent actions of tyramine in interaction with glutamate underlie central effects of monoamine oxidase inhibition

Trace Amine-Associated Receptor 5 Provides Olfactory Input Into Limbic Brain Areas and Modulates Emotional Behaviors and Serotonin Transmission

(2020) Stefano Espinoza et al.   Frontiers in Molecular Neuroscience

A Non–D2-Receptor-Binding Drug for the Treatment of Schizophrenia

(2020) Kenneth S. Koblan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Increased dopamine transmission and adult neurogenesis in trace amine-associated receptor 5 (TAAR5) knockout mice

(2020) Evgeniya V. Efimova et al.   NEUROPHARMACOLOGY

TAAR1 promotes anti-diabetic signaling in insulin-secreting cells

(2019) Emily S. Michael et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Astrocyte function from information processing to cognition and cognitive impairment

(2019) Mirko Santello et al.   NATURE NEUROSCIENCE

A Forward Chemical Genetic Screen Reveals Gut Microbiota Metabolites That Modulate Host Physiology

(2019) Haiwei Chen et al.   CELL

Trace amine-associated receptor 1 agonism promotes wakefulness without impairment of cognition in Cynomolgus macaques

(2019) Anushka V. Goonawardena et al.   NEUROPSYCHOPHARMACOLOGY

Different Circulating Trace Amine Profiles in De Novo and Treated Parkinson’s Disease Patients

(2019) Giovanni D’Andrea et al.   Scientific Reports

SEP-363856, A NOVEL PSYCHOTROPIC AGENT WITH A UNIQUE, NON-D2 RECEPTOR MECHANISM OF ACTION

(2019) Nina Dedic et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Amphetamines signal through intracellular TAAR1 receptors coupled to Gα13 and GαS in discrete subcellular domains

(2019) Suzanne M. Underhill et al.   MOLECULAR PSYCHIATRY

Comprehensive mapping of neurotransmitter networks by MALDI–MS imaging

(2019) Mohammadreza Shariatgorji et al.   NATURE METHODS

Genetic deletion of GPR88 enhances the locomotor response to L-DOPA in experimental parkinsonism while counteracting the induction of dyskinesia

(2019) Ioannis Mantas et al.   NEUROPHARMACOLOGY

Dopamine Evokes a Trace Amine Receptor-dependent Inward Current that is Regulated by AMP Kinase in Substantia Nigra Dopamine Neurons

(2019) Wei Yang et al.   NEUROSCIENCE

Trace Amines and Their Receptors

(2018) Raul R. Gainetdinov et al.   PHARMACOLOGICAL REVIEWS

Identifying human diamine sensors for death related putrescine and cadaverine molecules

(2018) Cristina Izquierdo et al.   PLoS Computational Biology

The Case for TAAR1 as a Modulator of Central Nervous System Function

(2018) Grazia Rutigliano et al.   Frontiers in Pharmacology

A Neural Circuit for Gut-Induced Reward

(2018) Wenfei Han et al.   CELL

Histamine: neural circuits and new medications

(2018) Thomas E Scammell et al.   SLEEP

Methamphetamine decreases K+ channel function in human fetal astrocytes by activating the trace amine-associated receptor type-1

(2018) Sonya Dave et al.   JOURNAL OF NEUROCHEMISTRY

Tranylcypromine in mind (Part I): Review of pharmacology

(2017) Sven Ulrich et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Interaction Between the Trace Amine-Associated Receptor 1 and the Dopamine D2 Receptor Controls Cocaine’s Neurochemical Actions

(2017) Aman Asif-Malik et al.   Scientific Reports

Striatal adenosine A2A receptor neurons control active-period sleep via parvalbumin neurons in external globus pallidus

(2017) Xiang-Shan Yuan et al.   eLife

The emerging roles of human trace amines and human trace amine-associated receptors (hTAARs) in central nervous system

(2016) Muhammad zahid khan et al.   BIOMEDICINE & PHARMACOTHERAPY

Lateral hypothalamic circuits for feeding and reward

(2016) Garret D Stuber et al.   NATURE NEUROSCIENCE

Dysregulation of the dopamine system in the pathophysiology of schizophrenia and depression

(2016) Anthony A. Grace   NATURE REVIEWS NEUROSCIENCE

Diversity of Dopaminergic Neural Circuits in Response to Drug Exposure

(2016) Barbara Juarez et al.   NEUROPSYCHOPHARMACOLOGY

Trace Amine-Associated Receptor 1 Regulates Wakefulness and EEG Spectral Composition

(2016) Michael D Schwartz et al.   NEUROPSYCHOPHARMACOLOGY

Incretin-like effects of small molecule trace amine-associated receptor 1 agonists

(2016) Susanne Raab et al.   Molecular Metabolism

Trace amine-associated receptors: ligands, neural circuits, and behaviors

(2015) Stephen D Liberles   CURRENT OPINION IN NEUROBIOLOGY

Modulation by Trace Amine-Associated Receptor 1 of Experimental Parkinsonism, L-DOPA Responsivity, and Glutamatergic Neurotransmission

(2015) A. Alvarsson et al.   JOURNAL OF NEUROSCIENCE

TAAR1 Modulates Cortical Glutamate NMDA Receptor Function

(2015) Stefano Espinoza et al.   NEUROPSYCHOPHARMACOLOGY

Ventral Subiculum Stimulation Promotes Persistent Hyperactivity of Dopamine Neurons and Facilitates Behavioral Effects of Cocaine

(2015) Christelle Glangetas et al.   Cell Reports

Dopamine neurons projecting to the posterior striatum form an anatomically distinct subclass

(2015) William Menegas et al.   eLife

Methamphetamine and HIV-1-induced neurotoxicity: Role of trace amine associated receptor 1 cAMP signaling in astrocytes

(2014) Irma E. Cisneros et al.   NEUROPHARMACOLOGY

NMDA receptor antagonists ketamine and Ro25-6981 inhibit evoked release of glutamate in vivo in the subiculum

(2014) T L Stan et al.   Translational Psychiatry

Metabolism of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine by Mitochondrion-targeted Cytochrome P450 2D6

(2012) Prachi Bajpai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A new perspective for schizophrenia: TAAR1 agonists reveal antipsychotic- and antidepressant-like activity, improve cognition and control body weight

(2012) F G Revel et al.   MOLECULAR PSYCHIATRY

Whole-Brain Mapping of Direct Inputs to Midbrain Dopamine Neurons

(2012) Mitsuko Watabe-Uchida et al.   NEURON

Brain-Specific Overexpression of Trace Amine-Associated Receptor 1 Alters Monoaminergic Neurotransmission and Decreases Sensitivity to Amphetamine

(2012) Florent G Revel et al.   NEUROPSYCHOPHARMACOLOGY

Genetic Deletion of Trace Amine 1 Receptors Reveals Their Role in Auto-Inhibiting the Actions of Ecstasy (MDMA)

(2011) B. Di Cara et al.   JOURNAL OF NEUROSCIENCE

Functional Interaction between Trace Amine-Associated Receptor 1 and Dopamine D2 Receptor

(2011) S. Espinoza et al.   MOLECULAR PHARMACOLOGY

TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity

(2011) F. G. Revel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry

(2010) Alexxai V. Kravitz et al.   NATURE

The selective antagonist EPPTB reveals TAAR1-mediated regulatory mechanisms in dopaminergic neurons of the mesolimbic system

(2009) A. Bradaia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differences between Dorsal and Ventral Striatum in Drd1a Dopamine Receptor Coupling of Dopamine- and cAMP-Regulated Phosphoprotein-32 to Activation of Extracellular Signal-Regulated Kinase

(2008) C. R. Gerfen et al.   JOURNAL OF NEUROSCIENCE

Opposing Patterns of Signaling Activation in Dopamine D1 and D2 Receptor-Expressing Striatal Neurons in Response to Cocaine and Haloperidol

(2008) J. Bertran-Gonzalez et al.   JOURNAL OF NEUROSCIENCE

Trace amine-associated receptors and their ligands

(2006) R Zucchi et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Activity-Regulated Cytoskeletal-Associated Protein Arc Is Expressed in Different Striosome-Matrix Patterns Following Exposure to Amphetamine and Cocaine

(2003) Andrew Tan et al.   JOURNAL OF NEUROCHEMISTRY