Melatonin Prevents against Ethanol-Induced Liver Injury by Mitigating Ferroptosis via Targeting Brain and Muscle ARNT-like 1 in Mice Liver and HepG2 Cells

Melatonin prevents diabetes‐associated cognitive dysfunction from microglia‐mediated neuroinflammation by activating autophagy via TLR4/Akt/mTOR pathway

(2021) Yixin Cui et al.   FASEB JOURNAL

Bmal1 Regulates Macrophage Polarize Through Glycolytic Pathway in Alcoholic Liver Disease

(2021) Yiwen Zhou et al.   Frontiers in Pharmacology

Melatonin induces Nrf2‐HO‐1 reprogramming and corrections in hepatic core clock oscillations in Non‐alcoholic fatty liver disease

(2021) Apeksha Joshi et al.   FASEB JOURNAL

Autophagy Inhibition Plays a Protective Role in Ferroptosis Induced by Alcohol via the p62–Keap1–Nrf2 Pathway

(2021) Yanan Zhao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Melatonin Alleviates Acute Sleep Deprivation-Induced Memory Loss in Mice by Suppressing Hippocampal Ferroptosis

(2021) Xintong Wang et al.   Frontiers in Pharmacology

Melatonin protects against PM2.5-induced lung injury by inhibiting ferroptosis of lung epithelial cells in a Nrf2-dependent manner

(2021) Fan Guohua et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Partial protective effects of melatonin on developing brain in a rat model of chorioamnionitis

(2021) Geraldine Favrais et al.   Scientific Reports

The circadian clock protects against ferroptosis-induced sterile inflammation

(2020) Yang Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Melatonin and circadian rhythms in liver diseases: Functional roles and potential therapies

(2020) Keisaku Sato et al.   JOURNAL OF PINEAL RESEARCH

Nedd4 ubiquitylates VDAC2/3 to suppress erastin-induced ferroptosis in melanoma

(2020) Yongfei Yang et al.   Nature Communications

High-Dose Melatonin and Ethanol Excipient Combined with Therapeutic Hypothermia in a Newborn Piglet Asphyxia Model

(2020) Nicola J. Robertson et al.   Scientific Reports

Ferroptosis is involved in alcohol-induced cell death in vivo and in vitro

(2020) Chun-Yu Liu et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Hepatoprotective effects of melatonin and celecoxib against ethanol-induced hepatotoxicity in rats

(2020) Ubaid Ullah et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Melatonin Protects Mouse Testes from Palmitic Acid‐Induced Lipotoxicity by Attenuating Oxidative Stress and DNA Damage in a SIRT1‐Dependent Manner

(2020) Dejun Xu et al.   JOURNAL OF PINEAL RESEARCH

Targeted inhibition of Rev‐erbα/β limits ferroptosis to ameliorate folic acid‐induced acute kidney injury

(2020) Lianxia Guo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Circadian clock gene BMAL1 reduces urinary calcium oxalate stones formation by regulating NRF2/HO-1 pathway

(2020) Jiahao Wang et al.   LIFE SCIENCES

Melatonin Suppresses Ferroptosis Induced by High Glucose via Activation of the Nrf2/HO-1 Signaling Pathway in Type 2 Diabetic Osteoporosis

(2020) Hongdong Ma et al.   Oxidative Medicine and Cellular Longevity

Oxidative stress-dependent frataxin inhibition mediated alcoholic hepatocytotoxicity through ferroptosis

(2020) Jingjing Liu et al.   TOXICOLOGY

Physcion Protects Against Ethanol-Induced Liver Injury by Reprogramming of Circadian Clock

(2020) Youli Yao et al.   Frontiers in Pharmacology

Acute-on-chronic liver failure in patients with alcohol-related liver disease

(2019) Thierry Gustot et al.   JOURNAL OF HEPATOLOGY

Licochalcone B Extracted from Glycyrrhiza uralensis Fisch Induces Apoptotic Effects in Human Hepatoma Cell HepG2

(2019) Jun Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Resveratrol Prevents Acrylamide-Induced Mitochondrial Dysfunction and Inflammatory Responses via Targeting Circadian Regulator Bmal1 and Cry1 in Hepatocytes

(2019) Xintong Tan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis

(2019) Masahiro Yoshida et al.   Nature Communications

Autophagic degradation of the circadian clock regulator promotes ferroptosis

(2019) Jiao Liu et al.   Autophagy

Sigma‐1 receptor protects against ferroptosis in hepatocellular carcinoma cells

(2019) Tao Bai et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Intestinal SIRT1 Deficiency Protects Mice from Ethanol-Induced Liver Injury by Mitigating Ferroptosis

(2019) Zhou Zhou et al.   AMERICAN JOURNAL OF PATHOLOGY

Arsenic induces pancreatic dysfunction and ferroptosis via mitochondrial ROS-autophagy-lysosomal pathway

(2019) Sen Wei et al.   JOURNAL OF HAZARDOUS MATERIALS

The tumor suppressor protein p53 and the ferroptosis network

(2018) Rui Kang et al.   FREE RADICAL BIOLOGY AND MEDICINE

The hepatic BMAL1/AKT/lipogenesis axis protects against alcoholic liver disease in mice via promoting PPARα pathway

(2018) Deqiang Zhang et al.   HEPATOLOGY

Melatonin modulates dysregulated circadian clocks in mice with diethylnitrosamine-induced hepatocellular carcinoma

(2018) Diana I. Sánchez et al.   JOURNAL OF PINEAL RESEARCH

Protective effect of exogenous melatonin in rats and their offspring on the genotoxic response induced by the chronic consumption of alcohol during pregnancy

(2018) Ilka Dayane Duarte de Sousa Coelho et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Melatonin Attenuates Dysregulation of the Circadian Clock Pathway in Mice With CCl4-Induced Fibrosis and Human Hepatic Stellate Cells

(2018) Bárbara González-Fernández et al.   Frontiers in Pharmacology

Daily Gene Expression Rhythms in Rat White Adipose Tissue Do Not Differ Between Subcutaneous and Intra-Abdominal Depots

(2018) Rianne van der Spek et al.   Frontiers in Endocrinology

Acrylamide Defects the Expression Pattern of the Circadian Clock and Mitochondrial Dynamics in C57BL/6J Mice Liver and HepG2 Cells

(2018) Xintong Tan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2

(2018) James O. Early et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Melatonin prevents senescence of canine adipose-derived mesenchymal stem cells through activating NRF2 and inhibiting ER stress

(2018) Jia Fang et al.   Aging-US

Tea polyphenols direct Bmal1-driven ameliorating of the redox imbalance and mitochondrial dysfunction in hepatocytes

(2018) Guoyuan Qi et al.   FOOD AND CHEMICAL TOXICOLOGY

Tea polyphenols ameliorates neural redox imbalance and mitochondrial dysfunction via mechanisms linking the key circadian regular Bmal1

(2017) Guoyuan Qi et al.   FOOD AND CHEMICAL TOXICOLOGY

Melatonin alleviates adipose inflammation through elevating α-ketoglutarate and diverting adipose-derived exosomes to macrophages in mice

(2017) Zhenjiang Liu et al.   JOURNAL OF PINEAL RESEARCH

Circadian rhythms, alcohol and gut interactions

(2015) Christopher B. Forsyth et al.   ALCOHOL

Diurnal Variation Has Effect on Differential Gene Expression Analysis in the Hippocampus of the Pilocarpine-Induced Model of Mesial Temporal Lobe Epilepsy

(2015) Evelin Antonieli da Silva Santos et al.   PLoS One

Palmitate Inhibits SIRT1-Dependent BMAL1/CLOCK Interaction and Disrupts Circadian Gene Oscillations in Hepatocytes

(2015) Xin Tong et al.   PLoS One

Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration

(2013) Erik S. Musiek et al.   JOURNAL OF CLINICAL INVESTIGATION

Melatonin and Vitamin C Ameliorate Alcohol-Induced Oxidative Stress and eNOS Expression in Rat Kidney

(2012) Mehmet Fatih Sönmez et al.   RENAL FAILURE