3D chromatin maps of the human pancreas reveal lineage-specific regulatory architecture of T2D risk
出版年份 2022 全文链接
标题
3D chromatin maps of the human pancreas reveal lineage-specific regulatory architecture of T2D risk
作者
关键词
-
出版物
Cell Metabolism
Volume 34, Issue 9, Pages 1394-1409.e4
出版商
Elsevier BV
发表日期
2022-09-06
DOI
10.1016/j.cmet.2022.08.014
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Variant-to-gene-mapping analyses reveal a role for pancreatic islet cells in conferring genetic susceptibility to sleep-related traits
- (2022) Chiara Lasconi et al. SLEEP
- FoxA-dependent demethylation of DNA initiates epigenetic memory of cellular identity
- (2021) Yitzhak Reizel et al. DEVELOPMENTAL CELL
- 3D promoter architecture re-organization during iPSC-derived neuronal cell differentiation implicates target genes for neurodevelopmental disorders
- (2021) Chun Su et al. PROGRESS IN NEUROBIOLOGY
- Comprehensive analysis of single cell ATAC-seq data with SnapATAC
- (2021) Rongxin Fang et al. Nature Communications
- A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traits
- (2021) Christopher N. Foley et al. Nature Communications
- Interpreting type 1 diabetes risk with genetics and single-cell epigenomics
- (2021) Joshua Chiou et al. NATURE
- Genome-wide enhancer maps link risk variants to disease genes
- (2021) Joseph Nasser et al. NATURE
- The trans-ancestral genomic architecture of glycemic traits
- (2021) Ji Chen et al. NATURE GENETICS
- Identifying statistically significant chromatin contacts from Hi-C data with FitHiC2
- (2020) Arya Kaul et al. Nature Protocols
- Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis
- (2020) Marijana Vujkovic et al. NATURE GENETICS
- High-Resolution mRNA and Secretome Atlas of Human Enteroendocrine Cells
- (2020) Joep Beumer et al. CELL
- Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts
- (2020) Sara R. Rashkin et al. Nature Communications
- Genetic mapping of etiologic brain cell types for obesity
- (2020) Pascal N Timshel et al. eLife
- A Multi-omic Integrative Scheme Characterizes Tissues of Action at Loci Associated with Type 2 Diabetes
- (2020) Jason M. Torres et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Bulk tissue cell type deconvolution with multi-subject single-cell expression reference
- (2019) Xuran Wang et al. Nature Communications
- Multiomic Profiling Identifies cis-Regulatory Networks Underlying Human Pancreatic β Cell Identity and Function
- (2019) Nathan Lawlor et al. Cell Reports
- Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates
- (2019) Hassan S. Dashti et al. Nature Communications
- Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms
- (2019) Samuel E. Jones et al. Nature Communications
- The Integrated Islet Distribution Program Answers the Call for Improved Human Islet Phenotyping and Reporting of Human Islet Characteristics in Research Articles
- (2019) Marcela Brissova et al. DIABETES
- Comprehensive Integration of Single-Cell Data
- (2019) Tim Stuart et al. CELL
- Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes
- (2019) Irene Miguel-Escalada et al. NATURE GENETICS
- Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk
- (2019) William W. Greenwald et al. Nature Communications
- WITHDRAWN: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9th edition
- (2019) Pouya Saeedi et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations
- (2019) Charles P. Fulco et al. NATURE GENETICS
- Fast, sensitive and accurate integration of single-cell data with Harmony
- (2019) Ilya Korsunsky et al. NATURE METHODS
- Circadian Entrainment Triggers Maturation of Human In Vitro Islets
- (2019) Juan R. Alvarez-Dominguez et al. Cell Stem Cell
- Multi-ethnic genome-wide association study for atrial fibrillation
- (2018) Carolina Roselli et al. NATURE GENETICS
- The role of the carboxyl ester lipase ( CEL ) gene in pancreatic disease
- (2018) Bente B. Johansson et al. PANCREATOLOGY
- HiCcompare: an R-package for joint normalization and comparison of HI-C datasets
- (2018) John C. Stansfield et al. BMC BIOINFORMATICS
- A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas
- (2018) H. Efsun Arda et al. Cell Systems
- Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
- (2018) Anubha Mahajan et al. NATURE GENETICS
- HiCRep: assessing the reproducibility of Hi-C data using a stratum-adjusted correlation coefficient
- (2017) Tao Yang et al. GENOME RESEARCH
- chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data
- (2017) Alicia N Schep et al. NATURE METHODS
- HiTAD: detecting the structural and functional hierarchies of topologically associating domains from chromatin interactions
- (2017) Xiao-Tao Wang et al. NUCLEIC ACIDS RESEARCH
- Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters
- (2016) Biola M. Javierre et al. CELL
- Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
- (2016) Zhihong Zhu et al. NATURE GENETICS
- Integration of ATAC-seq and RNA-seq identifies human alpha cell and beta cell signature genes
- (2016) Amanda M. Ackermann et al. Molecular Metabolism
- LDlink: a web-based application for exploring population-specific haplotype structure and linking correlated alleles of possible functional variants: Fig. 1.
- (2015) Mitchell J. Machiela et al. BIOINFORMATICS
- Role of transcription factors in the transdifferentiation of pancreatic islet cells
- (2015) T. van der Meulen et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Chromatin architecture reorganization during stem cell differentiation
- (2015) Jesse R. Dixon et al. NATURE
- Partitioning heritability by functional annotation using genome-wide association summary statistics
- (2015) Hilary K Finucane et al. NATURE GENETICS
- The diabetes gene Hhex maintains -cell differentiation and islet function
- (2014) J. Zhang et al. GENES & DEVELOPMENT
- Depression of Type I Diacylglycerol Kinases in Pancreatic β-Cells From Male Mice Results in Impaired Insulin Secretion
- (2013) Yukiko Kurohane Kaneko et al. ENDOCRINOLOGY
- Dynamic regulation of transcriptional states by chromatin and transcription factors
- (2013) Ty C. Voss et al. NATURE REVIEWS GENETICS
- Network for Pancreatic Organ Donors with Diabetes (nPOD): developing a tissue biobank for type 1 diabetes
- (2012) Martha Campbell-Thompson et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Iterative correction of Hi-C data reveals hallmarks of chromosome organization
- (2012) Maxim Imakaev et al. NATURE METHODS
- Transcriptional regulation of α-cell differentiation
- (2011) N. C. Bramswig et al. DIABETES OBESITY & METABOLISM
- Isolation of mouse pancreatic alpha, beta, duct and acinar populations with cell surface markers
- (2011) Craig Dorrell et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Foxa1 and Foxa2 Maintain the Metabolic and Secretory Features of the Mature β-Cell
- (2010) Nan Gao et al. MOLECULAR ENDOCRINOLOGY
- Prediction and Interaction in Complex Disease Genetics: Experience in Type 1 Diabetes
- (2009) David G. Clayton PLoS Genetics
- Is Pancreatic Diabetes (Type 3c Diabetes) Underdiagnosed and Misdiagnosed?
- (2008) P. D. Hardt et al. DIABETES CARE
- Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development
- (2008) N. Gao et al. GENES & DEVELOPMENT
- A HapMap harvest of insights into the genetics of common disease
- (2008) Teri A. Manolio et al. JOURNAL OF CLINICAL INVESTIGATION
- Genome-wide association studies for complex traits: consensus, uncertainty and challenges
- (2008) Mark I. McCarthy et al. NATURE REVIEWS GENETICS
- Genetic Mapping in Human Disease
- (2008) D. Altshuler et al. SCIENCE
- Model-based Analysis of ChIP-Seq (MACS)
- (2008) Yong Zhang et al. GENOME BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search