Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts

Cross-Cancer Pleiotropic Associations with Lung Cancer Risk in African Americans

(2019) Carissa C. Jones et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

HLA Class I and II Diversity Contributes to the Etiologic Heterogeneity of Non-Hodgkin Lymphoma Subtypes

(2018) Sophia S. Wang et al.   CANCER RESEARCH

TPC2 mediates autophagy progression and extracellular vesicle secretion in cancer cells

(2018) Wei Sun et al.   EXPERIMENTAL CELL RESEARCH

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

(2018) Fredrick R. Schumacher et al.   NATURE GENETICS

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Evolutionary Pressure against MHC Class II Binding Cancer Mutations

(2018) Rachel Marty et al.   CELL

Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity

(2018) Aida Ferreiro-Iglesias et al.   Nature Communications

Leveraging Polygenic Functional Enrichment to Improve GWAS Power

(2018) Gleb Kichaev et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

New approach for understanding genome variations in KEGG

(2018) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

CADD: predicting the deleteriousness of variants throughout the human genome

(2018) Philipp Rentzsch et al.   NUCLEIC ACIDS RESEARCH

Genetic susceptibility in cervical cancer: From bench to bedside

(2017) Afsane Bahrami et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Association analysis identifies 65 new breast cancer risk loci

(2017) Kyriaki Michailidou et al.   NATURE

Integrated genomic characterization of oesophageal carcinoma

(2017)   NATURE

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

(2017) Catherine M Phelan et al.   NATURE GENETICS

GEJ cancers: gastric or esophageal tumors? searching for the answer according to molecular identity

(2017) Williams Fernandes Barra et al.   Oncotarget

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations

(2016) G. Fehringer et al.   CANCER RESEARCH

Telomere structure and maintenance gene variants and risk of five cancer types

(2016) Sara Karami et al.   INTERNATIONAL JOURNAL OF CANCER

Familial Risk and Heritability of Cancer Among Twins in Nordic Countries

(2016) Lorelei A. Mucci et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Expression quantitative trait loci in long non-coding RNA PAX8-AS1 are associated with decreased risk of cervical cancer

(2016) Jing Han et al.   MOLECULAR GENETICS AND GENOMICS

Identification of context-dependent expression quantitative trait loci in whole blood

(2016) Daria V Zhernakova et al.   NATURE GENETICS

Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

(2015) Mark N. Kvale et al.   GENETICS

Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

(2015) Yambazi Banda et al.   GENETICS

Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate from genome-wide association studies and tissue-specific protein interactions

(2015) David C. Qian et al.   HUMAN MOLECULAR GENETICS

Integrative analysis of 111 reference human epigenomes

(2015) Anshul Kundaje et al.   NATURE

Partitioning heritability by functional annotation using genome-wide association summary statistics

(2015) Hilary K Finucane et al.   NATURE GENETICS

Predicting effects of noncoding variants with deep learning–based sequence model

(2015) Jian Zhou et al.   NATURE METHODS

Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

(2015) Mark N. Kvale et al.   GENETICS

Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

(2015) Yambazi Banda et al.   GENETICS

Cross-cancer pleiotropic analysis of endometrial cancer: PAGE and E2C2 consortia

(2014) Veronica Wendy Setiawan et al.   CARCINOGENESIS

VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2-dependent Ca2+ signaling

(2014) A. Favia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomarker analysis in oesophagogastric cancer: Results from the REAL3 and TransMAGIC trials

(2013) A.F.C. Okines et al.   EUROPEAN JOURNAL OF CANCER

Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia

(2013) Iona Cheng et al.   GUT

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

(2013) Rosalind A Eeles et al.   NATURE GENETICS

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

(2013) Kyriaki Michailidou et al.   NATURE GENETICS

Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk

(2013) Fergus J. Couch et al.   PLoS Genetics

Genetic Variants at 6p21.1 and 7p15.3 Are Associated with Risk of Multiple Cancers in Han Chinese

(2012) Guangfu Jin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Subset-Based Approach Improves Power and Interpretation for the Combined Analysis of Genetic Association Studies of Heterogeneous Traits

(2012) Samsiddhi Bhattacharjee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Common Variants at the 19p13.1 and ZNF365 Loci Are Associated with ER Subtypes of Breast Cancer and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

(2012) F. J. Couch et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

PACSIN 2 represses cellular migration through direct association with cyclin D1 but not its alternate splice form cyclin D1b

(2011) Hui Meng et al.   CELL CYCLE

Next generation genome-wide association tool: Design and coverage of a high-throughput European-optimized SNP array

(2011) Thomas J. Hoffmann et al.   GENOMICS

Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels

(2011) Hemang Parikh et al.   HUMAN GENETICS

Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript

(2011) Z. Kote-Jarai et al.   HUMAN GENETICS

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

(2011) Annegien Broeks et al.   HUMAN MOLECULAR GENETICS

Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia

(2011) E Ellinghaus et al.   LEUKEMIA

Genome-wide association study identifies three new melanoma susceptibility loci

(2011) Jennifer H Barrett et al.   NATURE GENETICS

Genome-wide association study identifies a common variant associated with risk of endometrial cancer

(2011) Amanda B Spurdle et al.   NATURE GENETICS

GWAS of Follicular Lymphoma Reveals Allelic Heterogeneity at 6p21.32 and Suggests Shared Genetic Susceptibility with Diffuse Large B-cell Lymphoma

(2011) Karin E. Smedby et al.   PLoS Genetics

A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci

(2010) Nathaniel Rothman et al.   NATURE GENETICS

Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3

(2010) Mark P Purdue et al.   NATURE GENETICS

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study

(2009) Rosalind A Eeles et al.   NATURE GENETICS

Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

(2009) Thorunn Rafnar et al.   NATURE GENETICS

Multiple newly identified loci associated with prostate cancer susceptibility

(2008) Rosalind A Eeles et al.   NATURE GENETICS