标题
SYK coordinates neuroprotective microglial responses in neurodegenerative disease
作者
关键词
-
出版物
CELL
Volume 185, Issue 22, Pages 4135-4152.e22
出版商
Elsevier BV
发表日期
2022-10-17
DOI
10.1016/j.cell.2022.09.030
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Deletion of Alzheimer's disease‐associated CD33 results in an inflammatory human microglia phenotype
- (2021) Jannis Wißfeld et al. GLIA
- Microglia use TAM receptors to detect and engulf amyloid β plaques
- (2021) Youtong Huang et al. NATURE IMMUNOLOGY
- Dysregulated phosphoinositide 3-kinase signaling in microglia: shaping chronic neuroinflammation
- (2021) Erskine Chu et al. Journal of Neuroinflammation
- Microglia and CD206+ border-associated mouse macrophages maintain their embryonic origin during Alzheimer’s disease
- (2021) Xiaoting Wu et al. eLife
- Dectin-1/Syk signaling triggers neuroinflammation after ischemic stroke in mice
- (2020) Xin-Chun Ye et al. Journal of Neuroinflammation
- Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
- (2020) Julia Marschallinger et al. NATURE NEUROSCIENCE
- AIM2 inflammasome surveillance of DNA damage shapes neurodevelopment
- (2020) Catherine R. Lammert et al. NATURE
- TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis
- (2020) Francesca Cignarella et al. ACTA NEUROPATHOLOGICA
- Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection
- (2020) Samantha J. Batista et al. Nature Communications
- Dynamic Responses of Microglia in Animal Models of Multiple Sclerosis
- (2020) Melanie J. Plastini et al. Frontiers in Cellular Neuroscience
- Modulation of β-Amyloid Fibril Formation in Alzheimer’s Disease by Microglia and Infection
- (2020) Madeleine R. Brown et al. Frontiers in Molecular Neuroscience
- Suppression of Syk activation by resveratrol inhibits MSU crystal-induced inflammation in human monocytes
- (2019) Yeon-Ho Chung et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
- (2019) John V. Pluvinage et al. NATURE
- TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer’s Disease
- (2019) Ana Griciuc et al. NEURON
- Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility
- (2019) SCIENCE
- Distinct Signaling Pathways Regulate TREM2 Phagocytic and NFκB Antagonistic Activities
- (2019) Hailan Yao et al. Frontiers in Cellular Neuroscience
- Heterozygous CX3CR1 Deficiency in Microglia Restores Neuronal β-Amyloid Clearance Pathways and Slows Progression of Alzheimer's Like-Disease in PS1-APP Mice
- (2019) Suzanne E. Hickman et al. Frontiers in Immunology
- Microglia-Mediated Neuroprotection, TREM2 , and Alzheimer’s Disease: Evidence From Optical Imaging
- (2018) Carlo Condello et al. BIOLOGICAL PSYCHIATRY
- Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration
- (2018) Aleksandra Deczkowska et al. CELL
- Mechanisms of protein toxicity in neurodegenerative diseases
- (2018) Chang Geon Chung et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Neuronal integrity and complement control synaptic material clearance by microglia after CNS injury
- (2018) Geoffrey T. Norris et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer’s Disease Models
- (2018) C.Y. Daniel Lee et al. NEURON
- SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer
- (2018) Ankit Malik et al. IMMUNITY
- GSK3 and Tau: Two Convergence Points in Alzheimer's Disease
- (2018) Felix Hernandez et al. JOURNAL OF ALZHEIMERS DISEASE
- Functional aspects of meningeal lymphatics in ageing and Alzheimer’s disease
- (2018) Sandro Da Mesquita et al. NATURE
- Microglia in neurodegeneration
- (2018) Suzanne Hickman et al. NATURE NEUROSCIENCE
- Nilvadipine in mild to moderate Alzheimer disease: A randomised controlled trial
- (2018) Brian Lawlor et al. PLOS MEDICINE
- CD22: A Regulator of Innate and Adaptive B Cell Responses and Autoimmunity
- (2018) Edward A. Clark et al. Frontiers in Immunology
- The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
- (2017) Susanne Krasemann et al. IMMUNITY
- TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy
- (2017) Shane M. Bemiller et al. Molecular Neurodegeneration
- Late onset Alzheimer’s disease genetics implicates microglial pathways in disease risk
- (2017) Anastasia G. Efthymiou et al. Molecular Neurodegeneration
- Alzheimer’s disease pathological lesions activate the spleen tyrosine kinase
- (2017) Jonas Elias Schweig et al. Acta Neuropathologica Communications
- A data-driven approach links microglia to pathology and prognosis in amyotrophic lateral sclerosis
- (2017) Johnathan Cooper-Knock et al. Acta Neuropathologica Communications
- Neuronal p38α mediates synaptic and cognitive dysfunction in an Alzheimer’s mouse model by controlling β-amyloid production
- (2017) Sandra Colié et al. Scientific Reports
- TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques
- (2016) Yaming Wang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
- (2015) Yaming Wang et al. CELL
- Inefficient clearance of myelin debris by microglia impairs remyelinating processes
- (2015) Antoine Lampron et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques
- (2015) Carlo Condello et al. Nature Communications
- Immune phenotypes of microglia in human neurodegenerative disease: challenges to detecting microglial polarization in human brains
- (2015) Douglas G. Walker et al. Alzheimers Research & Therapy
- Hyperphosphorylation of Tau at Ser396 occurs in the much earlier stage than appearance of learning and memory disorders in 5XFAD mice
- (2014) Takeshi Kanno et al. BEHAVIOURAL BRAIN RESEARCH
- The Spleen Tyrosine Kinase (Syk) Regulates Alzheimer Amyloid-β Production and Tau Hyperphosphorylation
- (2014) Daniel Paris et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glial response during cuprizone-induced de- and remyelination in the CNS: lessons learned
- (2014) Viktoria Gudi et al. Frontiers in Cellular Neuroscience
- Amyloid beta-induced glycogen synthase kinase 3β phosphorylated VDAC1 in Alzheimer's disease: Implications for synaptic dysfunction and neuronal damage
- (2013) P. Hemachandra Reddy BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Paracaspase MALT1 Deficiency Protects Mice from Autoimmune-Mediated Demyelination
- (2013) C. Mc Guire et al. JOURNAL OF IMMUNOLOGY
- CD33 Alzheimer's Risk-Altering Polymorphism, CD33 Expression, and Exon 2 Splicing
- (2013) M. Malik et al. JOURNAL OF NEUROSCIENCE
- A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation
- (2013) Tobias Goldmann et al. NATURE NEUROSCIENCE
- Transcriptome analysis of amoeboid and ramified microglia isolated from the corpus callosum of rat brain
- (2012) Rangarajan Parakalan et al. BMC NEUROSCIENCE
- Complement receptor-3 negatively regulates the phagocytosis of degenerated myelin through tyrosine kinase Syk and cofilin
- (2012) Smadar Hadas et al. Journal of Neuroinflammation
- Selectively Silencing GSK-3 Isoforms Reduces Plaques and Tangles in Mouse Models of Alzheimer's Disease
- (2012) D. E. Hurtado et al. JOURNAL OF NEUROSCIENCE
- T cell receptor/CARMA1/NF- B signaling controls T-helper (Th) 17 differentiation
- (2012) L. L. Molinero et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Altered risk-aversion and risk-taking behaviour in patients with Alzheimer's disease
- (2012) Juwon HA et al. Psychogeriatrics
- Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)
- (2011) Cris S Constantinescu et al. BRITISH JOURNAL OF PHARMACOLOGY
- Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during Experimental Autoimmune Encephalomyelitis
- (2011) Jason G Weinger et al. Journal of Neuroinflammation
- Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
- (2011) Stephen Sawcer et al. NATURE
- Activation of glycogen synthase kinase-3 beta mediates β-amyloid induced neuritic damage in Alzheimer's disease
- (2011) B. DaRocha-Souto et al. NEUROBIOLOGY OF DISEASE
- The role of Syk/CARD9 coupled C-type lectins in antifungal immunity
- (2010) Rebecca A. Drummond et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Multiple sclerosis: risk factors, prodromes, and potential causal pathways
- (2010) Sreeram V Ramagopalan et al. LANCET NEUROLOGY
- Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Aβ aggregation in the 5XFAD mouse model of Alzheimer's disease
- (2010) Sadim Jawhar et al. NEUROBIOLOGY OF AGING
- Axonopathy and cytoskeletal disruption in degenerative diseases of the central nervous system
- (2009) James C. Vickers et al. BRAIN RESEARCH BULLETIN
- The role of tau in neurodegeneration
- (2009) Tania F Gendron et al. Molecular Neurodegeneration
- Multiple Sclerosis: An Immune or Neurodegenerative Disorder?
- (2008) Bruce D. Trapp et al. Annual Review of Neuroscience
- Association of GSK3B With Alzheimer Disease and Frontotemporal Dementia
- (2008) Barbara A. J. Schaffer et al. ARCHIVES OF NEUROLOGY
- Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling
- (2008) Jennifer S. Ziegenfuss et al. NATURE
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