A data-driven approach links microglia to pathology and prognosis in amyotrophic lateral sclerosis

Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status

(2016) Laura Piccio et al.   ACTA NEUROPATHOLOGICA

The value of magnetic resonance imaging as a biomarker for amyotrophic lateral sclerosis: a systematic review

(2016) G. Grolez et al.   BMC Neurology

Lower motor neuron involvement in ALS assessed by motor unit number index (MUNIX): Long-term changes and reproducibility

(2016) Davood Fathi et al.   CLINICAL NEUROPHYSIOLOGY

sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers

(2016) Marc Suárez‐Calvet et al.   EMBO Molecular Medicine

Weighted gene co-expression based biomarker discovery for psoriasis detection

(2016) Sudharsana Sundarrajan et al.   GENE

Targeting microglia for the treatment of Alzheimer's Disease

(2016) Paul D. Wes et al.   GLIA

Cerebrospinal Fluid Markers of Alzheimer’s Disease Pathology and Microglial Activation are Associated with Altered White Matter Microstructure in Asymptomatic Adults at Risk for Alzheimer’s Disease

(2016) Kelsey E. Melah et al.   JOURNAL OF ALZHEIMERS DISEASE

Neuroprotective Effect of TREM-2 in Aging and Alzheimer’s Disease Model

(2016) Animesh Alexander Raha et al.   JOURNAL OF ALZHEIMERS DISEASE

Neuroinflammation: the devil is in the details

(2016) Damon J. DiSabato et al.   JOURNAL OF NEUROCHEMISTRY

Inflammatory Response in the CNS: Friend or Foe?

(2016) Marta Sochocka et al.   MOLECULAR NEUROBIOLOGY

Network-driven plasma proteomics expose molecular changes in the Alzheimer’s brain

(2016) Philipp A. Jaeger et al.   Molecular Neurodegeneration

Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease

(2016) Amanda Heslegrave et al.   Molecular Neurodegeneration

TREM2 variants: new keys to decipher Alzheimer disease pathogenesis

(2016) Marco Colonna et al.   NATURE REVIEWS NEUROSCIENCE

g:Profiler—a web server for functional interpretation of gene lists (2016 update)

(2016) Jüri Reimand et al.   NUCLEIC ACIDS RESEARCH

Early changes in CSF sTREM2 in dominantly inherited Alzheimers disease occur after amyloid deposition and neuronal injury

(2016) M. Suarez-Calvet et al.   Science Translational Medicine

Identifying module biomarkers from gastric cancer by differential correlation network

(2016) Xiaoping Liu et al.   OncoTargets and Therapy

Unsupervised data-driven stratification of mentalizing heterogeneity in autism

(2016) Michael V. Lombardo et al.   Scientific Reports

TREM2 regulates microglial cell activation in response to demyelination in vivo

(2015) Claudia Cantoni et al.   ACTA NEUROPATHOLOGICA

Cerebrovascular injury as a risk factor for amyotrophic lateral sclerosis: Table 1

(2015) Martin R Turner et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseases

(2015) Mike A. Nalls et al.   NEUROBIOLOGY OF AGING

Neurofilament light chain: A prognostic biomarker in amyotrophic lateral sclerosis

(2015) C.-H. Lu et al.   NEUROLOGY

The Spectrum of C9orf72-mediated Neurodegeneration and Amyotrophic Lateral Sclerosis

(2015) Johnathan Cooper-Knock et al.   Neurotherapeutics

Clinical Measures of Disease Progression in Amyotrophic Lateral Sclerosis

(2015) Seward B. Rutkove   Neurotherapeutics

Amyotrophic Lateral Sclerosis: Review

(2015) Johnny Salameh et al.   SEMINARS IN NEUROLOGY

Microglial cell dysregulation in brain aging and neurodegeneration

(2015) Rommy von Bernhardi et al.   Frontiers in Aging Neuroscience

TDP-43 pathology and neuronal loss in amyotrophic lateral sclerosis spinal cord

(2014) Johannes Brettschneider et al.   ACTA NEUROPATHOLOGICA

Phagocytosis of Microglia in the Central Nervous System Diseases

(2014) Ruying Fu et al.   MOLECULAR NEUROBIOLOGY

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis

(2014) G. Kleinberger et al.   Science Translational Medicine

TREM2Variant p.R47H as a Risk Factor for Sporadic Amyotrophic Lateral Sclerosis

(2014) Janet Cady et al.   JAMA Neurology

The neuropathology associated with repeat expansions in the C9ORF72 gene

(2013) Ian R. A. Mackenzie et al.   ACTA NEUROPATHOLOGICA

Stages of pTDP-43 pathology in amyotrophic lateral sclerosis

(2013) Johannes Brettschneider et al.   ANNALS OF NEUROLOGY

puma 3.0: improved uncertainty propagation methods for gene and transcript expression analysis

(2013) Xuejun Liu et al.   BMC BIOINFORMATICS

A network approach to diagnostic biomarkers in progressive supranuclear palsy

(2013) Jose A. Santiago et al.   MOVEMENT DISORDERS

Core module biomarker identification with network exploration for breast cancer metastasis

(2012) Ruoting Yang et al.   BMC BIOINFORMATICS

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

(2012) Thorlakur Jonsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chapter 11: Genome-Wide Association Studies

(2012) William S. Bush et al.   PLoS Computational Biology

Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis

(2011) David R. Beers et al.   BRAIN

Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS

(2011) Mariely DeJesus-Hernandez et al.   NEURON

The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function

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Weighted gene co-expression network analysis of the peripheral blood from Amyotrophic Lateral Sclerosis patients

(2009) Christiaan GJ Saris et al.   BMC GENOMICS

Neuroscience in the era of functional genomics and systems biology

(2009) Daniel H. Geschwind et al.   NATURE

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

(2009) Steffen Durinck et al.   Nature Protocols

Multi-tissue coexpression networks reveal unexpected subnetworks associated with disease

(2009) Radu Dobrin et al.   GENOME BIOLOGY

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation

(2008) Laura Piccio et al.   BRAIN

Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types

(2008) Joseph P. Doyle et al.   CELL