Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer’s Disease Models

标题
Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer’s Disease Models
作者
关键词
microglia, TREM2, Alzheimer’s disease, mouse, neuroinflammation, RNA-sequencing, reprogramming, BAC, amyloid plaque, gene dosage
出版物
NEURON
Volume 97, Issue 5, Pages 1032-1048.e5
出版商
Elsevier BV
发表日期
2018-03-08
DOI
10.1016/j.neuron.2018.02.002

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