标题
Sirtuins in metabolism, DNA repair and cancer
作者
关键词
Sirtuin, DNA damage, Metabolism, Cancer, Post-translation modification
出版物
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Volume 35, Issue 1, Pages -
出版商
Springer Nature
发表日期
2016-11-25
DOI
10.1186/s13046-016-0461-5
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Sirtuin 6 Modulates Hypoxia-Induced Autophagy in Nasal Polyp Fibroblasts via Inhibition of Glycolysis
- (2016) Chia-Tung Shun et al. American Journal of Rhinology & Allergy
- SIRT4 regulates cancer cell survival and growth after stress
- (2016) Seung Min Jeong et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- SIRT7 promotes genome integrity and modulates non‐homologous end joining DNA repair
- (2016) Berta N Vazquez et al. EMBO JOURNAL
- Obesity Is Associated With Low NAD+/SIRT Pathway Expression in Adipose Tissue of BMI-Discordant Monozygotic Twins
- (2016) Sakari Jukarainen et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Sirtuin-3 (SIRT3) protects pancreatic β-cells from endoplasmic reticulum (ER) stress-induced apoptosis and dysfunction
- (2016) Hao-Hao Zhang et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Acetylation of Mitochondrial Trifunctional Protein α-Subunit Enhances Its Stability To Promote Fatty Acid Oxidation and Is Decreased in Nonalcoholic Fatty Liver Disease
- (2016) Liang Guo et al. MOLECULAR AND CELLULAR BIOLOGY
- Circulating SIRT1 inversely correlates with epicardial fat thickness in patients with obesity
- (2016) S. Mariani et al. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
- Sirt1 is essential for resveratrol enhancement of hypoxia-induced autophagy in the type 2 diabetic nephropathy rat
- (2016) Liqun Ma et al. PATHOLOGY RESEARCH AND PRACTICE
- SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids
- (2016) Takamasa Tobita et al. PLoS One
- NAD+ as the Link Between Oxidative Stress, Inflammation, Caloric Restriction, Exercise, DNA Repair, Longevity, and Health Span
- (2016) Borut Poljsak et al. REJUVENATION RESEARCH
- ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA
- (2016) Hui Zhang et al. Cell Reports
- SIRT6 stabilizes DNA-dependent Protein Kinase at chromatin for DNA double-strand break repair
- (2016) Ronald A. McCord et al. Aging-US
- Insulin secretion impairment in Sirt6 knockout pancreatic β cells is mediated by suppression of the FoxO1-Pdx1-Glut2 pathway
- (2016) Mi-Young Song et al. Scientific Reports
- Mitochondrial Sirtuins and Their Relationships with Metabolic Disease and Cancer
- (2015) Surinder Kumar et al. ANTIOXIDANTS & REDOX SIGNALING
- SIRT5 regulation of ammonia-induced autophagy and mitophagy
- (2015) Lucia Polletta et al. Autophagy
- SIRT6 protein deacetylase interacts with MYH DNA glycosylase, APE1 endonuclease, and Rad9–Rad1–Hus1 checkpoint clamp
- (2015) Bor-Jang Hwang et al. BMC MOLECULAR BIOLOGY
- SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner
- (2015) Zhu Xu et al. CELL CYCLE
- SIRT3-dependent GOT2 acetylation status affects the malate-aspartate NADH shuttle activity and pancreatic tumor growth
- (2015) H. Yang et al. EMBO JOURNAL
- Sirtuin 7 promotes cellular survival following genomic stress by attenuation of DNA damage, SAPK activation and p53 response
- (2015) Shashi Kiran et al. EXPERIMENTAL CELL RESEARCH
- SIRT1 suppresses cardiomyocyte apoptosis in diabetic cardiomyopathy: An insight into endoplasmic reticulum stress response mechanism
- (2015) Rong Guo et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Cyclic AMP Signaling Reduces Sirtuin 6 Expression in Non-small Cell Lung Cancer Cells by Promoting Ubiquitin-Proteasomal Degradation via Inhibition of the Raf-MEK-ERK (Raf/Mitogen-activated Extracellular Signal-regulated Kinase/Extracellular Signal-regulated Kinase) Pathway
- (2015) Eui-Jun Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SIRT5 Regulates both Cytosolic and Mitochondrial Protein Malonylation with Glycolysis as a Major Target
- (2015) Yuya Nishida et al. MOLECULAR CELL
- Sirtuins in Cancer: a Balancing Act between Genome Stability and Metabolism
- (2015) Seung Min Jeong et al. MOLECULES AND CELLS
- Circulating SIRT1 Increases After Intragastric Balloon Fat Loss in Obese Patients
- (2015) Stefania Mariani et al. OBESITY SURGERY
- Emerging Role of Sirtuin 2 in the Regulation of Mammalian Metabolism
- (2015) Pedro Gomes et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- SIRT1 is involved in oncogenic signaling mediated by GPER in breast cancer
- (2015) M F Santolla et al. Cell Death & Disease
- Sirt7 promotes gastric cancer growth and inhibits apoptosis by epigenetically inhibiting miR-34a
- (2015) Shun Zhang et al. Scientific Reports
- Oxidative Stress Activates SIRT2 to Deacetylate and Stimulate Phosphoglycerate Mutase
- (2014) Y. Xu et al. CANCER RESEARCH
- SIRT6 Promotes COX-2 Expression and Acts as an Oncogene in Skin Cancer
- (2014) M. Ming et al. CANCER RESEARCH
- Sirtuin 4 Is a Lipoamidase Regulating Pyruvate Dehydrogenase Complex Activity
- (2014) Rommel A. Mathias et al. CELL
- SIRT7 Controls Hepatic Lipid Metabolism by Regulating the Ubiquitin-Proteasome Pathway
- (2014) Tatsuya Yoshizawa et al. Cell Metabolism
- Overexpression of Sirt7 Exhibits Oncogenic Property and Serves as a Prognostic Factor in Colorectal Cancer
- (2014) H. Yu et al. CLINICAL CANCER RESEARCH
- Resveratrol ameliorates diabetic vascular inflammation and macrophage infiltration in db/db mice by inhibiting the NF-κB pathway
- (2014) Rong Guo et al. Diabetes & Vascular Disease Research
- Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogramming
- (2014) B. M. M. Zwaans et al. Disease Models & Mechanisms
- The Many Faces of Sirtuins: Coupling of NAD metabolism, sirtuins and lifespan
- (2014) Eric Verdin NATURE MEDICINE
- SIRT2 regulates tumour hypoxia response by promoting HIF-1α hydroxylation
- (2014) K-S Seo et al. ONCOGENE
- Depletion of Sirtuin 1 (SIRT1) Leads to Epigenetic Modifications of Telomerase (TERT) Gene in Hepatocellular Carcinoma Cells
- (2014) Bin Zhang et al. PLoS One
- FOXO3a Potentiates hTERT Gene Expression by Activating c-MYC and Extends the Replicative Life-Span of Human Fibroblast
- (2014) Shuntaro Yamashita et al. PLoS One
- Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion
- (2014) P. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SIRT5 facilitates cancer cell growth and drug resistance in non-small cell lung cancer
- (2014) Weidong Lu et al. TUMOR BIOLOGY
- Sirt4: The Glutamine Gatekeeper
- (2013) Pablo J. Fernandez-Marcos et al. CANCER CELL
- SIRT6 modulates paclitaxel and epirubicin resistance and survival in breast cancer
- (2013) Mattaka Khongkow et al. CARCINOGENESIS
- The mTORC1 Pathway Stimulates Glutamine Metabolism and Cell Proliferation by Repressing SIRT4
- (2013) Alfred Csibi et al. CELL
- SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks
- (2013) Matthew J. Rardin et al. Cell Metabolism
- Sirtuins as Possible Drug Targets in Type 2 Diabetes
- (2013) Munehiro Kitada et al. CURRENT DRUG TARGETS
- Sirtuin 3 regulates mouse pancreatic beta cell function and is suppressed in pancreatic islets isolated from human type 2 diabetic patients
- (2013) P. W. Caton et al. DIABETOLOGIA
- SIRT2: Tumour suppressor or tumour promoter in operable breast cancer?
- (2013) Liane M. McGlynn et al. EUROPEAN JOURNAL OF CANCER
- Germline copy number variation of genes involved in chromatin remodelling in families suggestive of Li-Fraumeni syndrome with brain tumours
- (2013) Juliette Aury-Landas et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Intracellular distribution of human SIRT7 and mapping of the nuclear/nucleolar localization signal
- (2013) Shashi Kiran et al. FEBS Journal
- The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation
- (2013) L. Serrano et al. GENES & DEVELOPMENT
- Sirtuin-6-dependent genetic and epigenetic alterations are associated with poor clinical outcome in hepatocellular carcinoma patients
- (2013) Jens U. Marquardt et al. HEPATOLOGY
- SIRT2 overexpression in hepatocellular carcinoma mediates epithelial to mesenchymal transition by protein kinase B/glycogen synthase kinase-3β/β-catenin signaling
- (2013) Juan Chen et al. HEPATOLOGY
- Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
- (2013) Maimon E. Hubbi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Spontaneous Electrical Activity of Cultured Interstitial Cells of Cajal from Mouse Urinary Bladder
- (2013) Sun-Ouck Kim et al. KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY
- SIRT4 Represses Peroxisome Proliferator-Activated Receptor α Activity To Suppress Hepatic Fat Oxidation
- (2013) Gaëlle Laurent et al. MOLECULAR AND CELLULAR BIOLOGY
- Role of SIRT3 in the regulation of redox balance during oral carcinogenesis
- (2013) I-Chieh Chen et al. Molecular Cancer
- Acetylation Stabilizes ATP-Citrate Lyase to Promote Lipid Biosynthesis and Tumor Growth
- (2013) Ruiting Lin et al. MOLECULAR CELL
- SIRT4 Coordinates the Balance between Lipid Synthesis and Catabolism by Repressing Malonyl CoA Decarboxylase
- (2013) Gaëlle Laurent et al. MOLECULAR CELL
- SIRT6 Recruits SNF2H to DNA Break Sites, Preventing Genomic Instability through Chromatin Remodeling
- (2013) Debra Toiber et al. MOLECULAR CELL
- SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways
- (2013) Jeongsoon Park et al. MOLECULAR CELL
- SIRT1 collaborates with ATM and HDAC1 to maintain genomic stability in neurons
- (2013) Matthew M Dobbin et al. NATURE NEUROSCIENCE
- SIRT2 directs the replication stress response through CDK9 deacetylation
- (2013) H. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Altered expression of SIRT gene family in head and neck squamous cell carcinoma
- (2013) Chi-Chih Lai et al. TUMOR BIOLOGY
- Interaction of Sirt3 with OGG1 contributes to repair of mitochondrial DNA and protects from apoptotic cell death under oxidative stress
- (2013) Y Cheng et al. Cell Death & Disease
- SIRT7 Represses Myc Activity to Suppress ER Stress and Prevent Fatty Liver Disease
- (2013) Jiyung Shin et al. Cell Reports
- Multiple Regulatory Layers of SREBP1/2 by SIRT6
- (2013) Sivan Elhanati et al. Cell Reports
- Inhibition of SIRT6 in prostate cancer reduces cell viability and increases sensitivity to chemotherapeutics
- (2013) Yewei Liu et al. Protein & Cell
- Emerging beneficial roles of sirtuins in heart failure
- (2012) Masaya Tanno et al. BASIC RESEARCH IN CARDIOLOGY
- Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
- (2012) Patrick S. Ward et al. CANCER CELL
- The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism
- (2012) Carlos Sebastián et al. CELL
- The histone deacetylase SIRT2 stabilizes Myc oncoproteins
- (2012) P Y Liu et al. CELL DEATH AND DIFFERENTIATION
- Dietary obesity-associated Hif1 activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system
- (2012) J. Krishnan et al. GENES & DEVELOPMENT
- The NAD+-dependent Histone Deacetylase SIRT6 Promotes Cytokine Production and Migration in Pancreatic Cancer Cells by Regulating Ca2+Responses
- (2012) Inga Bauer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cortactin is associated with tumour progression and poor prognosis in prostate cancer and SIRT2 other than HADC6 may work as facilitator in situ
- (2012) Huilian Hou et al. JOURNAL OF CLINICAL PATHOLOGY
- SIRT3 Functions in the Nucleus in the Control of Stress-Related Gene Expression
- (2012) T. Iwahara et al. MOLECULAR AND CELLULAR BIOLOGY
- The Deacetylase Sirt6 Activates the Acetyltransferase GCN5 and Suppresses Hepatic Gluconeogenesis
- (2012) John E. Dominy et al. MOLECULAR CELL
- Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome
- (2012) Alexander S. Hebert et al. MOLECULAR CELL
- The many faces of insulin-like peptide signalling in the brain
- (2012) Ana M. Fernandez et al. NATURE REVIEWS NEUROSCIENCE
- SIRT1 promotes thyroid carcinogenesis driven by PTEN deficiency
- (2012) D Herranz et al. ONCOGENE
- Sirtuins and Disease: The Road Ahead
- (2012) Vincenzo Carafa et al. Frontiers in Pharmacology
- Editorial on Special Topic: Sirtuins in Metabolism, Aging, and Disease
- (2012) Aleksey G. Kazantsev et al. Frontiers in Pharmacology
- Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis
- (2011) H. Yuan et al. BLOOD
- SIRT2 Maintains Genome Integrity and Suppresses Tumorigenesis through Regulating APC/C Activity
- (2011) Hyun-Seok Kim et al. CANCER CELL
- SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization
- (2011) Lydia W.S. Finley et al. CANCER CELL
- Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6
- (2011) Eriko Michishita et al. CELL CYCLE
- The role of sirtuin 2 activation by nicotinamide phosphoribosyltransferase in the aberrant proliferation and survival of myeloid leukemia cells
- (2011) L. Dan et al. HAEMATOLOGICA
- Regulation of Glycolytic Enzyme Phosphoglycerate Mutase-1 by Sirt1 Protein-mediated Deacetylation
- (2011) William C. Hallows et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The SirT3 Divining Rod Points to Oxidative Stress
- (2011) Eric L. Bell et al. MOLECULAR CELL
- Acetylation Regulates Gluconeogenesis by Promoting PEPCK1 Degradation via Recruiting the UBR5 Ubiquitin Ligase
- (2011) Wenqing Jiang et al. MOLECULAR CELL
- SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production
- (2011) E L Bell et al. ONCOGENE
- SIRT6 Promotes DNA Repair Under Stress by Activating PARP1
- (2011) Z. Mao et al. SCIENCE
- Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase
- (2011) J. Du et al. SCIENCE
- Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells
- (2011) Praveen Rajendran et al. Clinical Epigenetics
- Mammalian Sirtuins: Biological Insights and Disease Relevance
- (2010) Marcia C. Haigis et al. Annual Review of Pathology-Mechanisms of Disease
- SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress
- (2010) Hyun-Seok Kim et al. CANCER CELL
- Targeting Mitochondrial Glutaminase Activity Inhibits Oncogenic Transformation
- (2010) Jian-Bin Wang et al. CANCER CELL
- Rethinking the Warburg Effect with Myc Micromanaging Glutamine Metabolism
- (2010) C. V. Dang CANCER RESEARCH
- The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α
- (2010) Lei Zhong et al. CELL
- Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation
- (2010) Xiaolei Qiu et al. Cell Metabolism
- SIRT3 Deacetylates Mitochondrial 3-Hydroxy-3-Methylglutaryl CoA Synthase 2 and Regulates Ketone Body Production
- (2010) Tadahiro Shimazu et al. Cell Metabolism
- Hepatic-Specific Disruption of SIRT6 in Mice Results in Fatty Liver Formation Due to Enhanced Glycolysis and Triglyceride Synthesis
- (2010) Hyun-Seok Kim et al. Cell Metabolism
- Role of SIRT1 in homologous recombination
- (2010) Miriam Uhl et al. DNA REPAIR
- A 4-Gene Signature Predicts Survival of Patients With Resected Adenocarcinoma of the Esophagus, Junction, and Gastric Cardia
- (2010) Christopher J. Peters et al. GASTROENTEROLOGY
- Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP
- (2010) A. K. Walker et al. GENES & DEVELOPMENT
- SIRT1 contributes to telomere maintenance and augments global homologous recombination
- (2010) Jose A. Palacios et al. JOURNAL OF CELL BIOLOGY
- SIRT6 in DNA repair, metabolism and ageing
- (2010) D. B. Lombard et al. JOURNAL OF INTERNAL MEDICINE
- Upregulated INHBA expression is associated with poor survival in gastric cancer
- (2010) Quan Wang et al. MEDICAL ONCOLOGY
- Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α
- (2010) Ji-Hong Lim et al. MOLECULAR CELL
- SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
- (2010) Matthew D. Hirschey et al. NATURE
- Genomic instability — an evolving hallmark of cancer
- (2010) Simona Negrini et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Glutamine addiction: a new therapeutic target in cancer
- (2010) David R. Wise et al. TRENDS IN BIOCHEMICAL SCIENCES
- Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer
- (2010) Daniel Herranz et al. Nature Communications
- SIRT6 protects against pathological damage caused by diet-induced obesity
- (2009) Yariv Kanfi et al. AGING CELL
- The Critical Role of the Class III Histone Deacetylase SIRT1 in Cancer
- (2009) T. Liu et al. CANCER RESEARCH
- Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation
- (2009) Aparna Purushotham et al. Cell Metabolism
- c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
- (2009) Ping Gao et al. NATURE
- AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
- (2009) Carles Cantó et al. NATURE
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Discovery, In Vivo Activity, and Mechanism of Action of a Small-Molecule p53 Activator
- (2008) Sonia Lain et al. CANCER CELL
- Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice
- (2008) Rui-Hong Wang et al. CANCER CELL
- SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging
- (2008) Philipp Oberdoerffer et al. CELL
- SIRT1 Modulation of the Acetylation Status, Cytosolic Localization, and Activity of LKB1
- (2008) Fan Lan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Substrates and Regulation Mechanisms for the Human Mitochondrial Sirtuins Sirt3 and Sirt5
- (2008) Christine Schlicker et al. JOURNAL OF MOLECULAR BIOLOGY
- SIRT3 Is a Stress-Responsive Deacetylase in Cardiomyocytes That Protects Cells from Stress-Mediated Cell Death by Deacetylation of Ku70
- (2008) N. R. Sundaresan et al. MOLECULAR AND CELLULAR BIOLOGY
- SIRT2 Suppresses Adipocyte Differentiation by Deacetylating FOXO1 and Enhancing FOXO1's Repressive Interaction with PPARγ
- (2008) Fei Wang et al. MOLECULAR BIOLOGY OF THE CELL
- Interplay among BRCA1, SIRT1, and Survivin during BRCA1-Associated Tumorigenesis
- (2008) Rui-Hong Wang et al. MOLECULAR CELL
- A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange
- (2008) Yi Liu et al. NATURE
- SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
- (2008) Eriko Michishita et al. NATURE
- Gene expression–based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study
- (2008) Kerby Shedden et al. NATURE MEDICINE
- Adaptation to hypoxia and acidosis in carcinogenesis and tumor progression
- (2008) Jennifer S. Fang et al. SEMINARS IN CANCER BIOLOGY
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