Cyclic AMP Signaling Reduces Sirtuin 6 Expression in Non-small Cell Lung Cancer Cells by Promoting Ubiquitin-Proteasomal Degradation via Inhibition of the Raf-MEK-ERK (Raf/Mitogen-activated Extracellular Signal-regulated Kinase/Extracellular Signal-regulated Kinase) Pathway
出版年份 2015 全文链接
标题
Cyclic AMP Signaling Reduces Sirtuin 6 Expression in Non-small Cell Lung Cancer Cells by Promoting Ubiquitin-Proteasomal Degradation via Inhibition of the Raf-MEK-ERK (Raf/Mitogen-activated Extracellular Signal-regulated Kinase/Extracellular Signal-regulated Kinase) Pathway
作者
关键词
-
出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 290, Issue 15, Pages 9604-9613
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2015-02-26
DOI
10.1074/jbc.m114.633198
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- SIRT6 Promotes COX-2 Expression and Acts as an Oncogene in Skin Cancer
- (2014) M. Ming et al. CANCER RESEARCH
- Leptin-Mediated Increases in Catecholamine Signaling Reduce Adipose Tissue Inflammation via Activation of Macrophage HDAC4
- (2014) Bing Luan et al. Cell Metabolism
- Recent Clinical Advances in Lung Cancer Management
- (2014) David H. Johnson et al. JOURNAL OF CLINICAL ONCOLOGY
- cAMP signaling inhibits radiation-induced ATM phosphorylation leading to the augmentation of apoptosis in human lung cancer cells
- (2014) Eun-Ah Cho et al. Molecular Cancer
- cAMP signaling in subcellular compartments
- (2014) Konstantinos Lefkimmiatis et al. PHARMACOLOGY & THERAPEUTICS
- MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancer
- (2014) U. Thirumurthi et al. Science Signaling
- PKA: Lessons learned after twenty years
- (2013) Susan S. Taylor et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Integrating leptin and cAMP signalling pathways in triple-negative breast cancer cells
- (2013) Silvio Naviglio Frontiers in Bioscience-Landmark
- Proteasomal Degradation of Eukaryotic Elongation Factor-2 Kinase (EF2K) Is Regulated by cAMP-PKA Signaling and the SCFβTRCPUbiquitin E3 Ligase
- (2013) Shari L. Wiseman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ras-mutant Cancer Cells Display B-Raf Binding to Ras That Activates Extracellular Signal-regulated Kinase and Is Inhibited by Protein Kinase A Phosphorylation
- (2013) Yanping Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Ubiquitin Ligase CHIP Prevents SirT6 Degradation through Noncanonical Ubiquitination
- (2013) Sarah M. Ronnebaum et al. MOLECULAR AND CELLULAR BIOLOGY
- The Short Isoform of the Ubiquitin Ligase NEDD4L Is a CREB Target Gene in Hepatocytes
- (2013) Jingqi Fu et al. PLoS One
- USP10 Antagonizes c-Myc Transcriptional Activation through SIRT6 Stabilization to Suppress Tumor Formation
- (2013) Zhenghong Lin et al. Cell Reports
- Inhibition of SIRT6 in prostate cancer reduces cell viability and increases sensitivity to chemotherapeutics
- (2013) Yewei Liu et al. Protein & Cell
- Vitamin D Protects Human Endothelial Cells from H2O2 Oxidant Injury Through the Mek/Erk-Sirt1 Axis Activation
- (2012) Lorella Polidoro et al. Journal of Cardiovascular Translational Research
- Global cancer statistics
- (2011) Ahmedin Jemal et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Heterotrimeric stimulatory GTP-binding proteins inhibit cisplatin-induced apoptosis by increasing X-linked inhibitor of apoptosis protein expression in cervical cancer cells
- (2011) Eun-Ah Cho et al. CANCER SCIENCE
- Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6
- (2011) Eriko Michishita et al. CELL CYCLE
- Developing Histone Deacetylase Inhibitors as Anti-Cancer Therapeutics
- (2011) B. Venugopal et al. CURRENT MEDICINAL CHEMISTRY
- Nicotinamide Phosphoribosyltransferase Is Essential for Interleukin-1β-mediated Dedifferentiation of Articular Chondrocytes via SIRT1 and Extracellular Signal-regulated Kinase (ERK) Complex Signaling
- (2011) Eun-Hee Hong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation of Peroxisome Proliferator-Activated Receptor Gamma by Rosiglitazone Increases Sirt6 Expression and Ameliorates Hepatic Steatosis in Rats
- (2011) Soo Jin Yang et al. PLoS One
- Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage
- (2011) H. C. Kang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling
- (2011) A. Davalos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of a Novel Biomarker, SEMA5A, for Non-Small Cell Lung Carcinoma in Nonsmoking Women
- (2010) T.-P. Lu et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α
- (2010) Lei Zhong et al. CELL
- Stimulatory heterotrimeric GTP-binding protein augments cisplatin-induced apoptosis by upregulating Bak expression in human lung cancer cells
- (2009) Yoon Jung Choi et al. CANCER SCIENCE
- SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span
- (2009) Tiara L.A. Kawahara et al. CELL
- Mechanisms Involved in 3′,5′-Cyclic Adenosine Monophosphate-Mediated Inhibition of the Ubiquitin-Proteasome System in Skeletal Muscle
- (2009) Dawit A. P. Gonçalves et al. ENDOCRINOLOGY
- Stimulatory heterotrimeric G protein augments gamma ray-induced apoptosis by up-regulation of Bak expression via CREB and AP-1 in H1299 human lung cancer cells
- (2009) Yoon Jung Choi et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Recent progress in the biology and physiology of sirtuins
- (2009) Toren Finkel et al. NATURE
- SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
- (2008) Eriko Michishita et al. NATURE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now