Tumor-Specific CD4+ T Cells Restrain Established Metastatic Melanoma by Developing Into Cytotoxic CD4– T Cells
出版年份 2022 全文链接
标题
Tumor-Specific CD4+ T Cells Restrain Established Metastatic Melanoma by Developing Into Cytotoxic CD4– T Cells
作者
关键词
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出版物
Frontiers in Immunology
Volume 13, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2022-06-16
DOI
10.3389/fimmu.2022.875718
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Harnessing Antitumor CD4+ T Cells for Cancer Immunotherapy
- (2022) Myriam Ben Khelil et al. Cancers
- Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination
- (2021) Jiali Yu et al. NATURE MEDICINE
- CD4+ T Cells: Multitasking Cells in the Duty of Cancer Immunotherapy
- (2021) Jennifer R. Richardson et al. Cancers
- Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes
- (2021) Jason M. Schenkel et al. IMMUNITY
- A reservoir of stem-like CD8 + T cells in the tumor-draining lymph node preserves the ongoing anti-tumor immune response
- (2021) Kelli A. Connolly et al. Science Immunology
- Dynamic CD4+ T cell heterogeneity defines subset-specific suppression and PD-L1-blockade-driven functional restoration in chronic infection
- (2021) Laura M. Snell et al. NATURE IMMUNOLOGY
- Progress and Challenges in Precise Treatment of Tumors With PD-1/PD-L1 Blockade
- (2020) Youhai Jiang et al. Frontiers in Immunology
- Intratumoral CD4+ T Cells Mediate Anti-tumor Cytotoxicity in Human Bladder Cancer
- (2020) David Y. Oh et al. CELL
- A peripheral immune signature of responsiveness to PD-1 blockade in patients with classical Hodgkin lymphoma
- (2020) Fathima Zumla Cader et al. NATURE MEDICINE
- The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes
- (2020) Floris Dammeijer et al. CANCER CELL
- TGF-β suppresses type 2 immunity to cancer
- (2020) Ming Liu et al. NATURE
- Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer
- (2020) Sri Krishna et al. SCIENCE
- Unlocking the therapeutic potential of primary tumor-draining lymph nodes
- (2019) Jossie Rotman et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Systems Biology of Cancer Metastasis
- (2019) Yasir Suhail et al. Cell Systems
- CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer
- (2019) Ryan Zander et al. IMMUNITY
- Single-Cell Profiling Defines Transcriptomic Signatures Specific to Tumor-Reactive versus Virus-Responsive CD4+ T Cells
- (2019) Assaf Magen et al. Cell Reports
- Th9 Cells Represent a Unique Subset of CD4 + T Cells Endowed with the Ability to Eradicate Advanced Tumors
- (2018) Yong Lu et al. CANCER CELL
- CD4+ T cell-mediated rejection of MHC class II-positive tumor cells is dependent on antigen secretion and indirect presentation on host APCs
- (2018) Ole Audun Werner Haabeth et al. CANCER RESEARCH
- Major Histocompatibility Complex Class II and Programmed Death Ligand 1 Expression Predict Outcome After Programmed Death 1 Blockade in Classic Hodgkin Lymphoma
- (2018) Margaretha G.M. Roemer et al. JOURNAL OF CLINICAL ONCOLOGY
- Tumor Regression and Cure Depends on Sustained Th1 Responses
- (2018) Min Dai et al. JOURNAL OF IMMUNOTHERAPY
- Tumor Killing by CD4+ T Cells Is Mediated via Induction of Inducible Nitric Oxide Synthase-Dependent Macrophage Cytotoxicity
- (2018) Marte Fauskanger et al. Frontiers in Immunology
- CD4 + T Cell Help Confers a Cytotoxic T Cell Effector Program Including Coinhibitory Receptor Downregulation and Increased Tissue Invasiveness
- (2017) Tomasz Ahrends et al. IMMUNITY
- Value of ablation therapy in the treatment of lung metastases
- (2017) Han Qi et al. Thoracic Cancer
- CD4 + T Cell and NK Cell Interplay Key to Regression of MHC Class I low Tumors upon TLR7/8 Agonist Therapy
- (2017) Elien M. Doorduijn et al. Cancer Immunology Research
- Melanoma Lesions Independently Acquire T-cell Resistance during Metastatic Latency
- (2016) F. Zhao et al. CANCER RESEARCH
- Emerging roles of T helper 17 and regulatory T cells in lung cancer progression and metastasis
- (2016) Erin A. Marshall et al. Molecular Cancer
- Follicular CXCR5-expressing CD8+ T cells curtail chronic viral infection
- (2016) Ran He et al. NATURE
- Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma
- (2016) Jesse M. Zaretsky et al. NEW ENGLAND JOURNAL OF MEDICINE
- The epigenetic landscape of T cell exhaustion
- (2016) D. R. Sen et al. SCIENCE
- New insights into type I interferon and the immunopathogenesis of persistent viral infections
- (2015) Laura M Snell et al. CURRENT OPINION IN IMMUNOLOGY
- Mutant MHC class II epitopes drive therapeutic immune responses to cancer
- (2015) Sebastian Kreiter et al. NATURE
- The transcription factor TCF-1 initiates the differentiation of TFH cells during acute viral infection
- (2015) Lifan Xu et al. NATURE IMMUNOLOGY
- Cutting Edge: Murine Cytomegalovirus Induces a Polyfunctional CD4 T Cell Response
- (2014) R. Arens et al. JOURNAL OF IMMUNOLOGY
- Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer
- (2014) E. Tran et al. SCIENCE
- Helper T cells down-regulate CD4 expression upon chronic stimulation giving rise to double-negative T cells
- (2013) Inna V. Grishkan et al. CELLULAR IMMUNOLOGY
- Tumor-reactive CD4+T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts
- (2010) Sergio A. Quezada et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Selection of CD8+PD-1+ Lymphocytes in Fresh Human Melanomas Enriches for Tumor-reactive T Cells
- (2010) Takashi Inozume et al. JOURNAL OF IMMUNOTHERAPY
- Distinct functions of antigen-specific CD4 T cells during murine Mycobacterium tuberculosis infection
- (2010) W. W. Reiley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
- (2009) M. Ahmadzadeh et al. BLOOD
- CD4 downregulation by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection
- (2009) Coreen M Beaumier et al. NATURE MEDICINE
- Tumor progression inhibits the induction of multifunctionality in adoptively transferred tumor-specific CD8+ T cells
- (2008) Naoko Imai et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Adoptive Cell Therapy for Patients With Metastatic Melanoma: Evaluation of Intensive Myeloablative Chemoradiation Preparative Regimens
- (2008) Mark E. Dudley et al. JOURNAL OF CLINICAL ONCOLOGY
- Treatment of Metastatic Melanoma with Autologous CD4+ T Cells against NY-ESO-1
- (2008) Naomi N. Hunder et al. NEW ENGLAND JOURNAL OF MEDICINE
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