The transcription factor TCF-1 initiates the differentiation of TFH cells during acute viral infection

BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms

(2015) Katerina Hatzi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pathophysiology of T follicular helper cells in humans and mice

(2015) Hideki Ueno et al.   NATURE IMMUNOLOGY

Dual role of Tlx3 as modulator of Prrxl1 transcription and phosphorylation

(2014) Isabel Regadas et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

T Follicular Helper Cell Differentiation, Function, and Roles in Disease

(2014) Shane Crotty   IMMUNITY

From inception to output, Tcf1 and Lef1 safeguard development of T cells and innate immune cells

(2014) Farrah C. Steinke et al.   IMMUNOLOGIC RESEARCH

T-bet and Eomesodermin Play Critical Roles in Directing T Cell Differentiation to Th1 versus Th17

(2014) Y. Yang et al.   JOURNAL OF IMMUNOLOGY

Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development

(2014) Xindong Liu et al.   NATURE

TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4+ T cell fate and interact with Runx3 to silence Cd4 in CD8+ T cells

(2014) Farrah C Steinke et al.   NATURE IMMUNOLOGY

A far downstream enhancer for murine Bcl11b controls its T-cell specific expression

(2013) L. Li et al.   BLOOD

Dynamic regulation of Bcl6 in follicular helper CD4 T (Tfh) cells

(2013) Youn Soo Choi et al.   CURRENT OPINION IN IMMUNOLOGY

Distinct Memory CD4+ T Cells with Commitment to T Follicular Helper- and T Helper 1-Cell Lineages Are Generated after Acute Viral Infection

(2013) J. Scott Hale et al.   IMMUNITY

Cutting Edge: STAT1 Is Required for IL-6-Mediated Bcl6 Induction for Early Follicular Helper Cell Differentiation

(2013) Y. S. Choi et al.   JOURNAL OF IMMUNOLOGY

Bcl6 Expressing Follicular Helper CD4 T Cells Are Fate Committed Early and Have the Capacity To Form Memory

(2013) Y. S. Choi et al.   JOURNAL OF IMMUNOLOGY

Interleukin-21 Is a Critical Cytokine for the Generation of Virus-Specific Long-Lived Plasma Cells

(2013) M. A. U. Rasheed et al.   JOURNAL OF VIROLOGY

Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility

(2013) Heping Xu et al.   NATURE

Regulation of mature T cell responses by the Wnt signaling pathway

(2012) Hai-Hui Xue et al.   Annals of the New York Academy of Sciences

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

The TCF-1 and LEF-1 Transcription Factors Have Cooperative and Opposing Roles in T Cell Development and Malignancy

(2012) Shuyang Yu et al.   IMMUNITY

STAT5 is a potent negative regulator of TFHcell differentiation

(2012) Robert J. Johnston et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Generation of Memory Precursors and Functional Memory CD8+ T Cells Depends on T Cell Factor-1 and Lymphoid Enhancer-Binding Factor-1

(2012) X. Zhou et al.   JOURNAL OF IMMUNOLOGY

Activating Transcription Factor 3 and the Nervous System

(2012) David Hunt et al.   Frontiers in Molecular Neuroscience

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

Early Th1 Cell Differentiation Is Marked by a Tfh Cell-like Transition

(2011) Shingo Nakayamada et al.   IMMUNITY

Differential Expression of Ly6C and T-bet Distinguish Effector and Memory Th1 CD4+ Cell Properties during Viral Infection

(2011) Heather D. Marshall et al.   IMMUNITY

T Cell Factor-1 Negatively Regulates Expression of IL-17 Family of Cytokines and Protects Mice from Experimental Autoimmune Encephalomyelitis

(2011) Qing Yu et al.   JOURNAL OF IMMUNOLOGY

A critical role for TCF-1 in T-lineage specification and differentiation

(2011) Brittany Nicole Weber et al.   NATURE

Efficient mucosal vaccination mediated by the neonatal Fc receptor

(2011) Lilin Ye et al.   NATURE BIOTECHNOLOGY

The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells

(2011) Wataru Ise et al.   NATURE IMMUNOLOGY

IL-21 and IL-6 Are Critical for Different Aspects of B Cell Immunity and Redundantly Induce Optimal Follicular Helper CD4 T Cell (Tfh) Differentiation

(2011) Danelle Eto et al.   PLoS One

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

Bcl-6 and NF- B cistromes mediate opposing regulation of the innate immune response

(2010) G. D. Barish et al.   GENES & DEVELOPMENT

Diverse Targets of the Transcription Factor STAT3 Contribute to T Cell Pathogenicity and Homeostasis

(2010) Lydia Durant et al.   IMMUNITY

Differentiation and Persistence of Memory CD8+ T Cells Depend on T Cell Factor 1

(2010) Xinyuan Zhou et al.   IMMUNITY

The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment

(2009) Di Yu et al.   IMMUNITY

T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-γ

(2009) Qing Yu et al.   NATURE IMMUNOLOGY

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

(2009) R. J. Johnston et al.   SCIENCE

Bcl6 Mediates the Development of T Follicular Helper Cells

(2009) R. I. Nurieva et al.   SCIENCE