Adipose methylome integrative-omic analyses reveal genetic and dietary metabolic health drivers and insulin resistance classifiers
出版年份 2022 全文链接
标题
Adipose methylome integrative-omic analyses reveal genetic and dietary metabolic health drivers and insulin resistance classifiers
作者
关键词
-
出版物
Genome Medicine
Volume 14, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-07-18
DOI
10.1186/s13073-022-01077-z
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Integrative Analysis of Glucometabolic Traits, Adipose Tissue DNA Methylation and Gene Expression Identifies Epigenetic Regulatory Mechanisms of Insulin Resistance and Obesity in African Americans
- (2020) Neeraj K. Sharma et al. DIABETES
- DNA methylation GrimAge strongly predicts lifespan and healthspan
- (2019) Ake T. Lu et al. Aging-US
- Epigenetic findings in periodontitis in UK twins: a cross-sectional study
- (2019) Yuko Kurushima et al. Clinical Epigenetics
- Dissecting features of epigenetic variants underlying cardiometabolic risk using full-resolution epigenome profiling in regulatory elements
- (2019) Fiona Allum et al. Nature Communications
- Nine Amino Acids are Associated with Decreased Insulin Secretion and Elevated Glucose Levels in a 4.6-Year Follow-Up Study of 5,181 Finnish Men
- (2019) Jagadish Vangipurapu et al. DIABETES
- Cell-Type Heterogeneity in Adipose Tissue Is Associated with Complex Traits and Reveals Disease-Relevant Cell-Specific eQTLs
- (2019) Craig A. Glastonbury et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The triglyceride synthesis enzymes DGAT1 and DGAT2 have distinct and overlapping functions in adipocytes
- (2019) Chandramohan Chitraju et al. JOURNAL OF LIPID RESEARCH
- Methylome and transcriptome maps of human visceral and subcutaneous adipocytes reveal key epigenetic differences at developmental genes
- (2019) Stephen T. Bradford et al. Scientific Reports
- Dissecting the role of the gut microbiota and diet on visceral fat mass accumulation
- (2019) Caroline I. Le Roy et al. Scientific Reports
- Genetic inactivation of the LIGHT (TNFSF14) cytokine in mice restores glucose homeostasis and diminishes hepatic steatosis
- (2019) Andrea Herrero-Cervera et al. DIABETOLOGIA
- Cytoskeletal transgelin 2 contributes to gender-dependent adipose tissue expandability and immune function
- (2019) Francisco J. Ortega et al. FASEB JOURNAL
- TwinsUK: The UK Adult Twin Registry Update
- (2019) Serena Verdi et al. Twin Research and Human Genetics
- An epigenetic biomarker of aging for lifespan and healthspan
- (2018) Morgan E. Levine et al. Aging-US
- Inhibition of FOXO1 transcription factor in primary human adipocytes mimics the insulin-resistant state of type 2 diabetes
- (2018) Meenu R. Rajan et al. BIOCHEMICAL JOURNAL
- Epigenome-wide association in adipose tissue from the METSIM cohort
- (2018) Luz D Orozco et al. HUMAN MOLECULAR GENETICS
- The case of GWAS of obesity: does body weight control play by the rules?
- (2018) Manfred J. Müller et al. INTERNATIONAL JOURNAL OF OBESITY
- Development and Evaluation of a Dietary Approaches to Stop Hypertension Dietary Index with Calorie-Based Standards in Equivalent Units: A Cross-Sectional Study with 24-Hour Dietary Recalls from Adult Participants in the National Health and Nutrition Examination Survey 2007-2010
- (2018) Masako Matsunaga et al. Journal of the Academy of Nutrition and Dietetics
- Diet Quality as Assessed by the Healthy Eating Index, Alternate Healthy Eating Index, Dietary Approaches to Stop Hypertension Score, and Health Outcomes: An Updated Systematic Review and Meta-Analysis of Cohort Studies
- (2018) Lukas Schwingshackl et al. Journal of the Academy of Nutrition and Dietetics
- Adipose tissue dysfunction is associated with low levels of the novel Palmitic Acid Hydroxystearic Acids
- (2018) Ann Hammarstedt et al. Scientific Reports
- The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019
- (2018) Annalisa Buniello et al. NUCLEIC ACIDS RESEARCH
- Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health
- (2018) Pei-Chien Tsai et al. Clinical Epigenetics
- lmerTest Package: Tests in Linear Mixed Effects Models
- (2017) Alexandra Kuznetsova et al. Journal of Statistical Software
- Metabolomic Profiling of Long-Term Weight Change: Role of Oxidative Stress and Urate Levels in Weight Gain
- (2017) Cristina Menni et al. Obesity
- A complete tool set for molecular QTL discovery and analysis
- (2017) Olivier Delaneau et al. Nature Communications
- Genome-wide DNA methylation analysis reveals loci that distinguish different types of adipose tissue in obese individuals
- (2017) Donia Macartney-Coxson et al. Clinical Epigenetics
- Metabolomics in Prediabetes and Diabetes: A Systematic Review and Meta-analysis
- (2016) Marta Guasch-Ferré et al. DIABETES CARE
- LIGHT/TNFSF14 is increased in patients with type 2 diabetes mellitus and promotes islet cell dysfunction and endothelial cell inflammation in vitro
- (2016) Bente Halvorsen et al. DIABETOLOGIA
- Lysophosphatidylcholine acyltransferase 1 protects against cytotoxicity induced by polyunsaturated fatty acids
- (2016) Sosuke Akagi et al. FASEB JOURNAL
- Epigenome-wide association study of body mass index and the adverse outcomes of adiposity
- (2016) Simone Wahl et al. NATURE
- Epigenetic Mediators Between Childhood Socioeconomic Disadvantage and Mid-Life Body Mass Index
- (2016) Eric B. Loucks et al. PSYCHOSOMATIC MEDICINE
- Leucine in Obesity: Therapeutic Prospects
- (2016) Kang Yao et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- The MDM2–p53–pyruvate carboxylase signalling axis couples mitochondrial metabolism to glucose-stimulated insulin secretion in pancreatic β-cells
- (2016) Xiaomu Li et al. Nature Communications
- A Genome-Wide mQTL Analysis in Human Adipose Tissue Identifies Genetic Variants Associated with DNA Methylation, Gene Expression and Metabolic Traits
- (2016) Petr Volkov et al. PLoS One
- missMethyl: an R package for analyzing data from Illumina’s HumanMethylation450 platform
- (2015) Belinda Phipson et al. BIOINFORMATICS
- coMET: visualisation of regional epigenome-wide association scan results and DNA co-methylation patterns
- (2015) Tiphaine C Martin et al. BMC BIOINFORMATICS
- Quantitative Serum Nuclear Magnetic Resonance Metabolomics in Cardiovascular Epidemiology and Genetics
- (2015) Pasi Soininen et al. Circulation-Cardiovascular Genetics
- ENmix: a novel background correction method for Illumina HumanMethylation450 BeadChip
- (2015) Zongli Xu et al. NUCLEIC ACIDS RESEARCH
- Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants
- (2015) Fiona Allum et al. Nature Communications
- FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization
- (2015) InSug O-Sullivan et al. Nature Communications
- Quantitative Serum Nuclear Magnetic Resonance Metabolomics in Cardiovascular Epidemiology and Genetics
- (2015) Pasi Soininen et al. Circulation-Cardiovascular Genetics
- Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements
- (2015) Weiwei Zhang et al. GENOME BIOLOGY
- Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study
- (2015) John C Chambers et al. Lancet Diabetes & Endocrinology
- Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays
- (2014) Martin J. Aryee et al. BIOINFORMATICS
- Reference-free cell mixture adjustments in analysis of DNA methylation data
- (2014) Eugene Andres Houseman et al. BIOINFORMATICS
- Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects
- (2014) Mark M. Yore et al. CELL
- Altered DNA Methylation and Differential Expression of Genes Influencing Metabolism and Inflammation in Adipose Tissue From Subjects With Type 2 Diabetes
- (2014) E. Nilsson et al. DIABETES
- Adiposity is associated with DNA methylation profile in adipose tissue
- (2014) Golareh Agha et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- The Epidemiology of Obesity: A Big Picture
- (2014) Adela Hruby et al. PHARMACOECONOMICS
- Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression
- (2014) B. P. Fairfax et al. SCIENCE
- PIK3R1 Mutations Cause Syndromic Insulin Resistance with Lipoatrophy
- (2013) Christel Thauvin-Robinet et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Global Analysis of DNA Methylation Variation in Adipose Tissue from Twins Reveals Links to Disease-Associated Variants in Distal Regulatory Elements
- (2013) Elin Grundberg et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Targeting Pyruvate Carboxylase Reduces Gluconeogenesis and Adiposity and Improves Insulin Resistance
- (2013) N. Kumashiro et al. DIABETES
- Charting a dynamic DNA methylation landscape of the human genome
- (2013) Michael J. Ziller et al. NATURE
- What causes the insulin resistance underlying obesity?
- (2013) Olga T. Hardy et al. Current Opinion in Endocrinology Diabetes and Obesity
- DNA methylation age of human tissues and cell types
- (2013) Steve Horvath GENOME BIOLOGY
- Matrix eQTL: ultra fast eQTL analysis via large matrix operations
- (2012) A. A. Shabalin BIOINFORMATICS
- DNA methylation arrays as surrogate measures of cell mixture distribution
- (2012) Eugene Houseman et al. BMC BIOINFORMATICS
- Dysfunctional Adiposity and the Risk of Prediabetes and Type 2 Diabetes in Obese Adults
- (2012) Ian J. Neeland et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Mapping cis- and trans-regulatory effects across multiple tissues in twins
- (2012) Elin Grundberg et al. NATURE GENETICS
- ChromHMM: automating chromatin-state discovery and characterization
- (2012) Jason Ernst et al. NATURE METHODS
- pROC: an open-source package for R and S+ to analyze and compare ROC curves
- (2011) Xavier Robin et al. BMC BIOINFORMATICS
- The clinical importance of visceral adiposity: a critical review of methods for visceral adipose tissue analysis
- (2011) A Shuster et al. BRITISH JOURNAL OF RADIOLOGY
- Healthy Aspects of the Nordic Diet Are Related to Lower Total Mortality
- (2011) Anja Olsen et al. JOURNAL OF NUTRITION
- Health and economic burden of the projected obesity trends in the USA and the UK
- (2011) Y Claire Wang et al. LANCET
- Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis
- (2010) Pan Du et al. BMC BIOINFORMATICS
- Extracellular Fatty Acid Synthase: A Possible Surrogate Biomarker of Insulin Resistance
- (2010) J. M. Fernandez-Real et al. DIABETES
- A regulatory role of LPCAT1 in the synthesis of inflammatory lipids, PAF and LPC, in the retina of diabetic mice
- (2009) Long Cheng et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- The Development of the Mediterranean-Style Dietary Pattern Score and Its Application to the American Diet in the Framingham Offspring Cohort
- (2009) Marcella E. Rumawas et al. JOURNAL OF NUTRITION
- The Medical Risks of Obesity
- (2009) Xavier Pi-Sunyer POSTGRADUATE MEDICINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now