Single-cell atlas of craniogenesis uncovers SOXC-dependent, highly proliferative, and myofibroblast-like osteodermal progenitors

Consolidation of the clinical and genetic definition of a SOX4-related neurodevelopmental syndrome

(2022) Marco Angelozzi et al.   JOURNAL OF MEDICAL GENETICS

The developing mouse coronal suture at single-cell resolution

(2021) D’Juan T. Farmer et al.   Nature Communications

Wnt7b-induced Sox11 functions enhance self-renewal and osteogenic commitment of bone marrow mesenchymal stem cells

(2020) Fanyuan Yu et al.   STEM CELLS

Single-Cell Transcriptomic Analyses of the Developing Meninges Reveal Meningeal Fibroblast Diversity and Function

(2020) John DeSisto et al.   DEVELOPMENTAL CELL

The myofibroblast at a glance

(2020) Pardis Pakshir et al.   JOURNAL OF CELL SCIENCE

Regulation of heterogeneous cancer-associated fibroblasts: the molecular pathology of activated signaling pathways

(2020) Go J. Yoshida   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Regulatory roles for SOX11 in development, stem cells and cancer

(2020) Siu Man Tsang et al.   SEMINARS IN CANCER BIOLOGY

Integrated Transcriptome and Network Analysis Reveals Spatiotemporal Dynamics of Calvarial Suturogenesis

(2020) Greg Holmes et al.   Cell Reports

Mice lacking substance P have normal bone modeling but diminished bone formation, increased resorption, and accelerated osteopenia with aging

(2020) Liping Wang et al.   BONE

De Novo SOX4 Variants Cause a Neurodevelopmental Disease Associated with Mild Dysmorphism

(2019) Ash Zawerton et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The single-cell transcriptional landscape of mammalian organogenesis

(2019) Junyue Cao et al.   NATURE

Developmental biology of the meninges

(2019) Krishnakali Dasgupta et al.   GENESIS

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling

(2019) Krishnakali Dasgupta et al.   DEVELOPMENTAL BIOLOGY

Mutations in TFAP2B and previously unimplicated genes of the BMP, Wnt, and Hedgehog pathways in syndromic craniosynostosis

(2019) Andrew T. Timberlake et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SOXopathies: Growing Family of Developmental Disorders Due to SOX Mutations

(2019) Marco Angelozzi et al.   TRENDS IN GENETICS

SOX4: The unappreciated oncogene

(2019) Carlos S. Moreno   SEMINARS IN CANCER BIOLOGY

SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair

(2019) Qi Miao et al.   Nature Communications

The Actin Cytoskeleton and Actin-Based Motility

(2018) Tatyana Svitkina   Cold Spring Harbor Perspectives in Biology

Inflammatory Cytokines Stabilize SOXC Transcription Factors to Mediate the Transformation of Fibroblast-Like Synoviocytes in Arthritic Disease

(2018) Pallavi Bhattaram et al.   Arthritis & Rheumatology

RNA velocity of single cells

(2018) Gioele La Manno et al.   NATURE

Ablation of theSox11Gene Results in Clefting of the Secondary Palate Resembling the Pierre Robin Sequence

(2016) Huarong Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin

(2015) Rachel Sennett et al.   DEVELOPMENTAL CELL

Twist1contributes to cranial bone initiation and dermal condensation by maintaining wnt signaling responsiveness

(2015) L. Henry Goodnough et al.   DEVELOPMENTAL DYNAMICS

SOXC Transcription Factors Induce Cartilage Growth Plate Formation in Mouse Embryos by Promoting Noncanonical WNT Signaling

(2015) Kenji Kato et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osterix-Cre Transgene Causes Craniofacial Bone Development Defect

(2014) Li Wang et al.   CALCIFIED TISSUE INTERNATIONAL

SRF Regulates Craniofacial Development through Selective Recruitment of MRTF Cofactors by PDGF Signaling

(2014) Harish N. Vasudevan et al.   DEVELOPMENTAL CELL

SOXC proteins amplify canonical WNT signaling to secure nonchondrocytic fates in skeletogenesis

(2014) Pallavi Bhattaram et al.   JOURNAL OF CELL BIOLOGY

Skeletal defects in Osterix-Cre transgenic mice

(2014) Wei Huang et al.   TRANSGENIC RESEARCH

De novo SOX11 mutations cause Coffin–Siris syndrome

(2014) Yoshinori Tsurusaki et al.   Nature Communications

Hand in glove: brain and skull in development and dysmorphogenesis

(2013) Joan T. Richtsmeier et al.   ACTA NEUROPATHOLOGICA

Sox4 Is a Master Regulator of Epithelial-Mesenchymal Transition by Controlling Ezh2 Expression and Epigenetic Reprogramming

(2013) Neha Tiwari et al.   CANCER CELL

Cardiac outflow tract development relies on the complex function of Sox4 and Sox11 in multiple cell types

(2013) Mandy H. Paul et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Sox proteins: regulators of cell fate specification and differentiation

(2013) Y. Kamachi et al.   DEVELOPMENT

CCN3 Protein Participates in Bone Regeneration as an Inhibitory Factor

(2013) Yuki Matsushita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Transcription Factor Protein Sox11 Enhances Early Osteoblast Differentiation by Facilitating Proliferation and the Survival of Mesenchymal and Osteoblast Progenitors

(2013) Jogeswar Gadi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct fibroblast lineages determine dermal architecture in skin development and repair

(2013) Ryan R. Driskell et al.   NATURE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

The human calvaria: a review of embryology, anatomy, pathology, and molecular development

(2011) R. Shane Tubbs et al.   CHILDS NERVOUS SYSTEM

Role of canonical Wnt signaling/ -catenin via Dermo1 in cranial dermal cell development

(2010) T. H. Tran et al.   DEVELOPMENT

Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors

(2010) Pallavi Bhattaram et al.   Nature Communications

EphA4 as an effector of Twist1 in the guidance of osteogenic precursor cells during calvarial bone growth and in craniosynostosis

(2009) M.-C. Ting et al.   DEVELOPMENT

Tgfbr2 is required for development of the skull vault

(2009) Hwa-Seon Seo et al.   DEVELOPMENTAL BIOLOGY

Nephroblastoma Overexpressed (Nov) Inactivation Sensitizes Osteoblasts to Bone Morphogenetic Protein-2, But Nov Is Dispensable for Skeletal Homeostasis

(2009) Ernesto Canalis et al.   ENDOCRINOLOGY

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Sox12 Deletion in the Mouse Reveals Nonreciprocal Redundancy with the Related Sox4 and Sox11 Transcription Factors

(2008) M. Hoser et al.   MOLECULAR AND CELLULAR BIOLOGY

The three SoxC proteins—Sox4, Sox11 and Sox12—exhibit overlapping expression patterns and molecular properties

(2008) Peter Dy et al.   NUCLEIC ACIDS RESEARCH