SOXC proteins amplify canonical WNT signaling to secure nonchondrocytic fates in skeletogenesis

A novel genome-wide in vivo screen for metastatic suppressors in human colon cancer identifies the positive WNT-TCF pathway modulators TMED3 and SOX12

(2014) A. Duquet et al.   EMBO Molecular Medicine

Multivesicular GSK3 Sequestration upon Wnt Signaling Is Controlled by p120-Catenin/Cadherin Interaction with LRP5/6

(2014) Meritxell Vinyoles et al.   MOLECULAR CELL

SOX11 contributes to the regulation of GDF5 in joint maintenance

(2013) Akinori Kan et al.   BMC DEVELOPMENTAL BIOLOGY

Sox4 Is a Master Regulator of Epithelial-Mesenchymal Transition by Controlling Ezh2 Expression and Epigenetic Reprogramming

(2013) Neha Tiwari et al.   CANCER CELL

Cardiac outflow tract development relies on the complex function of Sox4 and Sox11 in multiple cell types

(2013) Mandy H. Paul et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Sox proteins: regulators of cell fate specification and differentiation

(2013) Y. Kamachi et al.   DEVELOPMENT

The Transcription Factor Protein Sox11 Enhances Early Osteoblast Differentiation by Facilitating Proliferation and the Survival of Mesenchymal and Osteoblast Progenitors

(2013) Jogeswar Gadi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

WNT signaling in bone homeostasis and disease: from human mutations to treatments

(2013) Roland Baron et al.   NATURE MEDICINE

Wnt Stabilization of  -Catenin Reveals Principles for Morphogen Receptor-Scaffold Assemblies

(2013) S.-E. Kim et al.   SCIENCE

Development of the Endochondral Skeleton

(2013) F. Long et al.   Cold Spring Harbor Perspectives in Biology

SOX4 enables oncogenic survival signals in acute lymphoblastic leukemia

(2012) P. Ramezani-Rad et al.   BLOOD

Wnt Signaling through Inhibition of β-Catenin Degradation in an Intact Axin1 Complex

(2012) Vivian S.W. Li et al.   CELL

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

The many faces and functions of β-catenin

(2012) Tomas Valenta et al.   EMBO JOURNAL

Sox4 functions as a positive regulator of β-catenin signaling through upregulation of TCF4 during morular differentiation of endometrial carcinomas

(2012) Makoto Saegusa et al.   LABORATORY INVESTIGATION

The role of SRY-related HMG box transcription factor 4 (SOX4) in tumorigenesis and metastasis: friend or foe?

(2012) S J Vervoort et al.   ONCOGENE

Kinetic Responses of  -Catenin Specify the Sites of Wnt Control

(2012) A. R. Hernandez et al.   SCIENCE

Wnt Signaling in Bone Development and Disease: Making Stronger Bone with Wnts

(2012) J. B. Regard et al.   Cold Spring Harbor Perspectives in Biology

SOX4 interacts with plakoglobin in a Wnt3a-dependent manner in prostate cancer cells

(2011) Yu-Heng Lai et al.   BMC CELL BIOLOGY

Sequentially acting Sox transcription factors in neural lineage development

(2011) M. Bergsland et al.   GENES & DEVELOPMENT

Sequential requirement of Sox4 and Sox11 during development of the sympathetic nervous system

(2010) M. R. Potzner et al.   DEVELOPMENT

The closely related transcription factors Sox4 and Sox11 function as survival factors during spinal cord development

(2010) Daniela C. Thein et al.   JOURNAL OF NEUROCHEMISTRY

Open for business

(2010)   Nature Communications

Mice expressing GFP and CreER in osteochondro progenitor cells in the periosteum

(2009) Aya Kawanami et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sox9 Inhibits Wnt Signaling by Promoting β-Catenin Phosphorylation in the Nucleus

(2008) Lilia Topol et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sox12 Deletion in the Mouse Reveals Nonreciprocal Redundancy with the Related Sox4 and Sox11 Transcription Factors

(2008) M. Hoser et al.   MOLECULAR AND CELLULAR BIOLOGY