Acylcarnitines: Nomenclature, Biomarkers, Therapeutic Potential, Drug Targets, and Clinical Trials
出版年份 2022 全文链接
标题
Acylcarnitines: Nomenclature, Biomarkers, Therapeutic Potential, Drug Targets, and Clinical Trials
作者
关键词
-
出版物
PHARMACOLOGICAL REVIEWS
Volume 74, Issue 3, Pages 506-551
出版商
American Society for Pharmacology & Experimental Therapeutics (ASPET)
发表日期
2022-06-16
DOI
10.1124/pharmrev.121.000408
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A student centric method for calculation of fatty acid energetics: Integrated formula and web tool
- (2021) Paras Jain et al. BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION
- Energy substrate metabolism and mitochondrial oxidative stress in cardiac ischemia/reperfusion injury
- (2021) Maija Dambrova et al. FREE RADICAL BIOLOGY AND MEDICINE
- Impact of newborn screening on the reported incidence and clinical outcomes associated with medium- and long-chain fatty acid oxidation disorders
- (2021) Deborah Marsden et al. GENETICS IN MEDICINE
- L-Carnitine and Acylcarnitines: Mitochondrial Biomarkers for Precision Medicine
- (2021) Marc R. McCann et al. Metabolites
- Potential Role of L-Carnitine in Autism Spectrum Disorder
- (2021) Alina Kępka et al. Journal of Clinical Medicine
- Long-Chain Acylcarnitines Decrease the Phosphorylation of the Insulin Receptor at Tyr1151 Through a PTP1B-Dependent Mechanism
- (2021) Karlis Vilks et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Ischemic heart failure mortality is not predicted by cardiac insulin resistance but by diabetes per se and coronary flow reserve: A retrospective dynamic cardiac 18F-FDG PET study
- (2021) Thien Vinh Luong et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- HMDB 5.0: the Human Metabolome Database for 2022
- (2021) David S Wishart et al. NUCLEIC ACIDS RESEARCH
- Screening of potential biomarkers for Yin‐deficiency‐heat syndrome based on UHPLC–MS method and the mechanism of Zhibai Dihuang granule therapeutic effect
- (2020) Wen‐Jing Yi et al. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
- Blood carnitine profiling on tandem mass spectrometry in liver cirrhotic patients
- (2020) Hisamitsu Miyaaki et al. BMC GASTROENTEROLOGY
- Potential therapeutic role of carnitine and acetylcarnitine in neurological disorders.
- (2020) Cecilia Maldonado et al. CURRENT PHARMACEUTICAL DESIGN
- Lipids and Ketones Dominate Metabolism at the Expense of Glucose Control in Pulmonary Arterial Hypertension: A Hyperglycemic Clamp and Metabolomics Study
- (2020) Jacob T. Mey et al. EUROPEAN RESPIRATORY JOURNAL
- Neonatal Macrosomia is an Interfering Factor for Analytes on the Colorado State Newborn Screen
- (2020) Erica L Wright et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Prepregnant Obesity of Mothers in a Multiethnic Cohort Is Associated with Cord Blood Metabolomic Changes in Offspring
- (2020) Ryan J. Schlueter et al. JOURNAL OF PROTEOME RESEARCH
- Carnitine in Human Muscle Bioenergetics: Can Carnitine Supplementation Improve Physical Exercise?
- (2020) Antonio Gnoni et al. MOLECULES
- Identification of the urine and serum metabolomics signature of gout
- (2020) Yefei Huang et al. RHEUMATOLOGY
- A Plasma Metabolomic Profiling of Exudative Age-Related Macular Degeneration Showing Carnosine and Mitochondrial Deficiencies
- (2020) Juan M. Chao de la Barca et al. Journal of Clinical Medicine
- Carnitine palmitoyltransferase 2 (CPT2) knockout potentiates palmitate‐induced insulin resistance in C2C12 myotubes
- (2020) Michael L. Blackburn et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Mass Spectral Library of Acylcarnitines Derived from Human Urine
- (2020) Xinjian Yan et al. ANALYTICAL CHEMISTRY
- Empagliflozin Protects Cardiac Mitochondrial Fatty Acid Metabolism in a Mouse Model of Diet-Induced Lipid Overload
- (2020) Marina Makrecka-Kuka et al. CARDIOVASCULAR DRUGS AND THERAPY
- Electrophysiological Abnormalities in VLCAD Deficient hiPSC-Cardiomyocytes Can Be Improved by Lowering Accumulation of Fatty Acid Oxidation Intermediates
- (2020) Suzan J. G. Knottnerus et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Muscle Carnitine Palmitoyltransferase II (CPT II) Deficiency: A Conceptual Approach
- (2020) Pushpa Raj Joshi et al. MOLECULES
- Acetyl-L-Carnitine in Dementia and Other Cognitive Disorders: A Critical Update
- (2020) Manuela Pennisi et al. Nutrients
- Plasma Metabolomic Markers of Insulin Resistance and Diabetes and Rate of Incident Parkinson’s Disease
- (2020) Samantha Molsberry et al. Journal of Parkinsons Disease
- The Association Between Acylcarnitine Metabolites and Cardiovascular Disease in Chinese Patients With Type 2 Diabetes Mellitus
- (2020) Shuo Zhao et al. Frontiers in Endocrinology
- Role of mitochondrial acyl-CoA dehydrogenases in the metabolism of dicarboxylic fatty acids
- (2020) Sivakama S. Bharathi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Relationship between the plasma acylcarnitine profile and cardiometabolic risk factors in adults diagnosed with cardiovascular diseases
- (2020) Alexey Kukharenko et al. CLINICA CHIMICA ACTA
- Targeted Metabolomics for Plasma Amino Acids and Carnitines in Patients with Metabolic Syndrome Using HPLC-MS/MS
- (2020) Li-li Gong et al. DISEASE MARKERS
- Plasma metabolites associated with biomarker evidence of neurodegeneration in cognitively normal older adults
- (2020) Pratishtha Chatterjee et al. JOURNAL OF NEUROCHEMISTRY
- A genetic screen identifies Crat as a regulator of pancreatic beta-cell insulin secretion
- (2020) Dassine Berdous et al. Molecular Metabolism
- Altered Metabolome of Lipids and Amino Acids Species: A Source of Early Signature Biomarkers of T2DM
- (2020) Ahsan Hameed et al. Journal of Clinical Medicine
- Stearoyl-CoA desaturase 5 (SCD5), a Δ-9 fatty acyl desaturase in search of a function
- (2020) R. Ariel Igal et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Newborn screening for isovaleric acidemia in Quanzhou, China
- (2020) Yiming Lin et al. CLINICA CHIMICA ACTA
- Triheptanoin: First Approval
- (2020) Matt Shirley DRUGS
- Liquid chromatography-mass spectrometry untargeted metabolomics reveals increased levels of tryptophan indole metabolites in urine of metabolic syndrome patients
- (2020) Moises Guerrero Esperanza et al. EUROPEAN JOURNAL OF MASS SPECTROMETRY
- Inhibition of CPT2 exacerbates cardiac dysfunction and inflammation in experimental endotoxaemia
- (2020) Marina Makrecka‐Kuka et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Determination of urinary carnitine levels as a potential indicator of uterine fibroids caused by nonylphenol exposure
- (2020) Jin-Ming Wang et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Effects of triheptanoin ( UX007 ) in patients with long‐chain fatty acid oxidation disorders: Results from an open‐label , long‐term extension study
- (2020) Jerry Vockley et al. JOURNAL OF INHERITED METABOLIC DISEASE
- The bright and the dark sides of L-carnitine supplementation: a systematic review
- (2020) Angelika K. Sawicka et al. Journal of the International Society of Sports Nutrition
- Effects of fasting, feeding and exercise on plasma acylcarnitines among subjects with CPT2D, VLCADD and LCHADD/TFPD
- (2020) Gabriela Elizondo et al. MOLECULAR GENETICS AND METABOLISM
- Novel biomarkers and age-related metabolite correlations in plasma and dried blood spots from patients with succinic semialdehyde dehydrogenase deficiency
- (2020) Trevor Kirby et al. Orphanet Journal of Rare Diseases
- Long-Chain Acylcarnitines and Cardiac Excitation-Contraction Coupling: Links to Arrhythmias
- (2020) Hamish M. Aitken-Buck et al. Frontiers in Physiology
- The Oral Glucose Tolerance Test: 100 Years Later
- (2020) Ram Jagannathan et al. Diabetes Metabolic Syndrome and Obesity-Targets and Therapy
- Insulin directly stimulates mitochondrial glucose oxidation in the heart
- (2020) Qutuba G. Karwi et al. Cardiovascular Diabetology
- An Examination of Serum Acylcarnitine and Amino Acid Profiles at Different Time Point of Ketogenic Diet Therapy and Their Association of Ketogenic Diet Effectiveness
- (2020) Pi-Lien Hung et al. Nutrients
- Structure Annotation of All Mass Spectra in Untargeted Metabolomics
- (2019) Ivana Blaženović et al. ANALYTICAL CHEMISTRY
- Characterizing acyl-carnitine biosignatures for schizophrenia: a longitudinal pre- and post-treatment study
- (2019) Bing Cao et al. Translational Psychiatry
- Mutation analysis of genes related to methylmalonic acidemia: identification of eight novel mutations
- (2019) Fatemeh Keyfi et al. MOLECULAR BIOLOGY REPORTS
- Clinical, biochemical, and molecular spectrum of short/branched-chain acyl-CoA dehydrogenase deficiency: two new cases and review of literature
- (2019) Francesco Porta et al. JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
- Metabolitic profiling of amino acids in paraquat-induced acute kidney injury
- (2019) Xiuxian Wan et al. Clinical and Experimental Nephrology
- Amino acid and Fatty Acid Metabolomic Profile during Fasting and Hyperinsulinemia in girls with Polycystic Ovarian Syndrome
- (2019) Melanie Cree-Green et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Poor Efficacy of L-Acetylcarnitine in the Treatment of Asthenozoospermia in Patients with Type 1 Diabetes
- (2019) Rosita A. Condorelli et al. Journal of Clinical Medicine
- Metabolic profiling for water-soluble metabolites in patients with schizophrenia and healthy controls in a Chinese population: A case-control study
- (2019) Bing Cao et al. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
- Fatty Acid Metabolites Combine with Reduced β Oxidation to Activate Th17 Inflammation in Human Type 2 Diabetes
- (2019) Dequina A. Nicholas et al. Cell Metabolism
- Free Fatty Acid Receptors in Health and Disease
- (2019) Ikuo Kimura et al. PHYSIOLOGICAL REVIEWS
- Untargeted metabolomics analysis of rat hippocampus subjected to sleep fragmentation
- (2019) Dae Wui Yoon et al. BRAIN RESEARCH BULLETIN
- Metabolomics signatures in type 2 diabetes: a systematic review and integrative analysis
- (2019) Yue Sun et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- A study on a cohort of 301 Chinese patients with isolated methylmalonic acidemia
- (2019) Lulu Kang et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Liver transplantation in children with propionic acidaemia – medium term outcomes
- (2019) Richard Curnock et al. LIVER TRANSPLANTATION
- Brain and blood metabolome for Alzheimer's dementia: findings from a targeted metabolomics analysis
- (2019) Zhiguang Huo et al. NEUROBIOLOGY OF AGING
- The β-oxidation pathway is downregulated during diapause termination in Calanus copepods
- (2019) Elise Skottene et al. Scientific Reports
- Systemic and central nervous system metabolic alterations in Alzheimer’s disease
- (2019) Vera van der Velpen et al. Alzheimers Research & Therapy
- Carnitine supplementation improves metabolic flexibility and skeletal muscle acetylcarnitine formation in volunteers with impaired glucose tolerance: A randomised controlled trial
- (2019) Yvonne MH Bruls et al. EBioMedicine
- Comprehensive Metabolomic Search for Biomarkers to Differentiate Early Stage Hepatocellular Carcinoma from Cirrhosis
- (2019) Kim et al. Cancers
- Acylcarnitine: Useful biomarker for early diagnosis of hepatocellular carcinoma in non-steatohepatitis patients
- (2019) Hiroaki Takaya et al. World Journal of Gastrointestinal Oncology
- Altered mitochondrial metabolism in the insulin‐resistant heart
- (2019) Marina Makrecka‐Kuka et al. Acta Physiologica
- Preoperative plasma fatty acid metabolites inform risk of prostate cancer progression and may be used for personalized patient stratification
- (2019) Eugenio Zoni et al. BMC CANCER
- Plasma metabolites as possible biomarkers for diagnosis of breast cancer
- (2019) Jiwon Park et al. PLoS One
- Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth
- (2019) Marta Palomo-Guerrero et al. eLife
- Decreases in Circulating Concentrations of Long-Chain Acylcarnitines and Free Fatty Acids During the Glucose Tolerance Test Represent Tissue-Specific Insulin Sensitivity
- (2019) Elina Makarova et al. Frontiers in Endocrinology
- Metabolomic study of human tissue and urine in clear cell renal carcinoma by LC-HRMS and PLS-DA
- (2018) Joanna Nizioł et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Strategy for Comprehensive Identification of Acylcarnitines Based on Liquid Chromatography–High-Resolution Mass Spectrometry
- (2018) Di Yu et al. ANALYTICAL CHEMISTRY
- Medium-Chain Acylcarnitines Are Associated With Cardioembolic Stroke and Stroke Recurrence
- (2018) Woo-Keun Seo et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Cytosolic carnitine acetyltransferase as a source of cytosolic acetyl-CoA: a possible mechanism for regulation of cardiac energy metabolism
- (2018) Tariq R. Altamimi et al. BIOCHEMICAL JOURNAL
- Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder
- (2018) Lakshmi N Yatham et al. BIPOLAR DISORDERS
- Dietary supplements and fatigue in patients with breast cancer: a systematic review
- (2018) Paula Tâmara Vieira Teixeira Pereira et al. BREAST CANCER RESEARCH AND TREATMENT
- Pharmacometabolomics reveals a role for histidine, phenylalanine, and threonine in the development of paclitaxel-induced peripheral neuropathy
- (2018) Yihan Sun et al. BREAST CANCER RESEARCH AND TREATMENT
- Increased cardiac fatty acid oxidation in a mouse model with decreased malonyl-CoA sensitivity of CPT1B
- (2018) Michel van Weeghel et al. CARDIOVASCULAR RESEARCH
- Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis
- (2018) Ajit S. Divakaruni et al. Cell Metabolism
- Etomoxir Actions on Regulatory and Memory T Cells Are Independent of Cpt1a-Mediated Fatty Acid Oxidation
- (2018) Brenda Raud et al. Cell Metabolism
- Elevated Medium-Chain Acylcarnitines Are Associated With Gestational Diabetes Mellitus and Early Progression to Type 2 Diabetes and Induce Pancreatic β-Cell Dysfunction
- (2018) Battsetseg Batchuluun et al. DIABETES
- Risk of gestational diabetes mellitus in relation to plasma concentrations of amino acids and acylcarnitines: A nested case-control study
- (2018) Cynthia Roy et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Metabolic flexibility as an adaptation to energy resources and requirements in health and disease
- (2018) Reuben L Smith et al. ENDOCRINE REVIEWS
- Organic acidurias in adults: late complications and management
- (2018) Ali Tunç Tuncel et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Two-Year Trends of Taxane-Induced Neuropathy in Women Enrolled in a Randomized Trial of Acetyl-L-Carnitine (SWOG S0715)
- (2018) Dawn L Hershman et al. JNCI-Journal of the National Cancer Institute
- Alternations of Metabolic Profile and Kynurenine Metabolism in the Plasma of Parkinson’s Disease
- (2018) Kuo-Hsuan Chang et al. MOLECULAR NEUROBIOLOGY
- Acetyl-L-Carnitine Supplementation and the Treatment of Depressive Symptoms
- (2018) Nicola Veronese et al. PSYCHOSOMATIC MEDICINE
- Disorders of mitochondrial long-chain fatty acid oxidation and the carnitine shuttle
- (2018) Suzan J. G. Knottnerus et al. REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
- Septic Shock Nonsurvivors Have Persistently Elevated Acylcarnitines Following Carnitine Supplementation
- (2018) Michael A. Puskarich et al. SHOCK
- Lower plasma choline levels are associated with sleepiness symptoms
- (2018) Victoria M. Pak et al. SLEEP MEDICINE
- An Inflammation-Centric View of Neurological Disease: Beyond the Neuron
- (2018) Stephen D. Skaper et al. Frontiers in Cellular Neuroscience
- A Nonsense Variant in the ACADVL Gene in German Hunting Terriers with Exercise Induced Metabolic Myopathy
- (2018) Vincent Lepori et al. G3-Genes Genomes Genetics
- Metabolic Biomarkers in Heart Failure
- (2018) Chonyang L. Albert et al. Heart Failure Clinics
- Two-Year Trends of Taxane-Induced Neuropathy in Women Enrolled in a Randomized Trial of Acetyl-L-Carnitine (SWOG S0715)
- (2018) Dawn L Hershman et al. JNCI-Journal of the National Cancer Institute
- Exploring the entry route of palmitic acid and palmitoylcarnitine into myoglobin
- (2018) Sree V. Chintapalli et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Metabolomic identification of diagnostic serum-based biomarkers for advanced stage melanoma
- (2018) A. W. L. Bayci et al. Metabolomics
- The metabolomic plasma profile of myeloma patients is considerably different from healthy subjects and reveals potential new therapeutic targets
- (2018) Normann Steiner et al. PLoS One
- Acetyl-l-carnitine deficiency in patients with major depressive disorder
- (2018) Carla Nasca et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metabolomic analysis of obesity, metabolic syndrome, and type 2 diabetes: amino acid and acylcarnitine levels change along a spectrum of metabolic wellness
- (2018) Diane M. Libert et al. PeerJ
- Untargeted metabolomics profiles delineate metabolic alterations in mouse plasma during lung carcinoma development using UPLC-QTOF/MS in MSE mode
- (2018) Huan Wu et al. Royal Society Open Science
- Branched Chain Amino Acids
- (2018) Michael Neinast et al. Annual Review of Physiology
- Peroxisomes can oxidize medium- and long-chain fatty acids through a pathway involving ABCD3 and HSD17B4
- (2018) Sara Violante et al. FASEB JOURNAL
- Urinary metabonomic study of patients with acute coronary syndrome using UPLC-QTOF/MS
- (2018) Yingfeng Wang et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Metabolomics identifies increases in the acylcarnitine profiles in the plasma of overweight subjects in response to mild weight loss: a randomized, controlled design study
- (2018) Miso Kang et al. Lipids in Health and Disease
- Acetyl-L-Carnitine to Enhance Nerve Regeneration in Carpal Tunnel Syndrome
- (2018) Matthew W. T. Curran et al. PLASTIC AND RECONSTRUCTIVE SURGERY
- Glutaric acidemia type II patient with thalassemia minor and novel electron transfer flavoprotein-A gene mutations: A case report and review of literature
- (2018) Neslihan Yildirim Saral et al. World Journal of Clinical Cases
- Loss of cardiac carnitine palmitoyltransferase 2 results in rapamycin-resistant, acetylation-independent hypertrophy
- (2017) Andrea S. Pereyra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Triheptanoin versus trioctanoin for long-chain fatty acid oxidation disorders: a double blinded, randomized controlled trial
- (2017) Melanie B. Gillingham et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Evaluation of C26:0-lysophosphatidylcholine and C26:0-carnitine as diagnostic markers for Zellweger spectrum disorders
- (2017) Femke C. C. Klouwer et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Developmental regulation and localization of carnitine palmitoyltransferases (CPTs) in rat brain
- (2017) Jennifer N. Jernberg et al. JOURNAL OF NEUROCHEMISTRY
- Profiling of Acylcarnitines in First Episode Psychosis before and after Antipsychotic Treatment
- (2017) Kärt Kriisa et al. JOURNAL OF PROTEOME RESEARCH
- Urinary Metabolomic Signatures in Obstructive Sleep Apnea through Targeted Metabolomic Analysis: A Pilot Study
- (2017) Kumsun Cho et al. Metabolomics
- Association of cultured myotubes and fasting plasma metabolite profiles with mitochondrial dysfunction in type 2 diabetes subjects
- (2017) Mohamad Hafizi Abu Bakar et al. Molecular BioSystems
- Identification and diagnostic value of phytanoyl- and pristanoyl-carnitine in plasma from patients with peroxisomal disorders
- (2017) Katharina Herzog et al. MOLECULAR GENETICS AND METABOLISM
- 3-Hydroxy-3-methylglutaryl-coenzyme A lyase deficiency: Clinical presentation and outcome in a series of 37 patients
- (2017) Sarah Catharina Grünert et al. MOLECULAR GENETICS AND METABOLISM
- Newborn screening for carnitine palmitoyltransferase II deficiency using (C16 + C18:1)/C2: Evaluation of additional indices for adequate sensitivity and lower false-positivity
- (2017) Go Tajima et al. MOLECULAR GENETICS AND METABOLISM
- HMDB 4.0: the human metabolome database for 2018
- (2017) David S Wishart et al. NUCLEIC ACIDS RESEARCH
- Comprehensive Metabolomic Profiling and Incident Cardiovascular Disease: A Systematic Review
- (2017) Miguel Ruiz‐Canela et al. Journal of the American Heart Association
- Estimating the total number of phosphoproteins and phosphorylation sites in eukaryotic proteomes
- (2017) Panayotis Vlastaridis et al. GigaScience
- Plasma Palmitoyl-Carnitine (AC16:0) Is a Marker of Increased Postprandial Nonesterified Incomplete Fatty Acid Oxidation Rate in Adults With Type 2 Diabetes
- (2017) Fatima-Zahra Bouchouirab et al. Canadian Journal of Diabetes
- Simultaneous determination of 3-hydroxypropionic acid, methylmalonic acid and methylcitric acid in dried blood spots: Second-tier LC-MS/MS assay for newborn screening of propionic acidemia, methylmalonic acidemias and combined remethylation disorders
- (2017) Péter Monostori et al. PLoS One
- Decreased long-chain acylcarnitines from insufficient β-oxidation as potential early diagnostic markers for Parkinson’s disease
- (2017) Shinji Saiki et al. Scientific Reports
- Complementary ACSL isoforms contribute to a non-Warburg advantageous energetic status characterizing invasive colon cancer cells
- (2017) Ruth Sánchez-Martínez et al. Scientific Reports
- Plasma acylcarnitine concentrations reflect the acylcarnitine profile in cardiac tissues
- (2017) Marina Makrecka-Kuka et al. Scientific Reports
- Plasma acylcarnitines and risk of cardiovascular disease: effect of Mediterranean diet interventions
- (2016) Marta Guasch-Ferré et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- A new case of malonyl-CoA decarboxylase deficiency with mild clinical features
- (2016) Huan Liu et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Metabolomics in diabetes, a review
- (2016) Rigoberto Pallares-Méndez et al. ANNALS OF MEDICINE
- The Biochemistry and Physiology of Mitochondrial Fatty Acid β-Oxidation and Its Genetic Disorders
- (2016) Sander M. Houten et al. Annual Review of Physiology
- Plasma acylcarnitines during insulin stimulation in humans are reflective of age-related metabolic dysfunction
- (2016) Leslie A. Consitt et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Long-chain acylcarnitines determine ischaemia/reperfusion-induced damage in heart mitochondria
- (2016) E. Liepinsh et al. BIOCHEMICAL JOURNAL
- Carnitine transport and fatty acid oxidation
- (2016) Nicola Longo et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder
- (2016) Arun V. Ravindran et al. CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE
- Acetylcarnitine Is a Candidate Diagnostic and Prognostic Biomarker of Hepatocellular Carcinoma
- (2016) Y. Lu et al. CANCER RESEARCH
- Fatty Acid Metabolic Defects and Right Ventricular Lipotoxicity in Human Pulmonary Arterial HypertensionClinical Perspective
- (2016) Evan L. Brittain et al. CIRCULATION
- Serum metabonomics of NAFLD plus T2DM based on liquid chromatography–mass spectrometry
- (2016) Yang Chen et al. CLINICAL BIOCHEMISTRY
- Acetyl-L-Carnitine Augmentation of Clozapine in Partial-Responder Schizophrenia
- (2016) Antonio Bruno et al. CLINICAL NEUROPHARMACOLOGY
- Mitochondrial Dysfunction and Biogenesis in Neurodegenerative diseases: Pathogenesis and Treatment
- (2016) Mojtaba Golpich et al. CNS Neuroscience & Therapeutics
- 2. Classification and Diagnosis of Diabetes
- (2016) DIABETES CARE
- Molecular and biochemical evidence on the protection of cardiomyocytes from phosphine-induced oxidative stress, mitochondrial dysfunction and apoptosis by acetyl-l-carnitine
- (2016) Amir Baghaei et al. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
- Low levels of short- and medium-chain acylcarnitines in HIV-infected patients
- (2016) Bjørn Waagsbø et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Metabolic support for the heart: complementary therapy for heart failure?
- (2016) Ward A. Heggermont et al. EUROPEAN JOURNAL OF HEART FAILURE
- Acylcarnitines as markers of exercise-associated fuel partitioning, xenometabolism, and potential signals to muscle afferent neurons
- (2016) Jie Zhang et al. EXPERIMENTAL PHYSIOLOGY
- The neurobiology of acetyl-L-carnitine
- (2016) Giovanna Traina Frontiers in Bioscience-Landmark
- Plasma metabolomics identified novel metabolites associated with risk of type 2 diabetes in two prospective cohorts of Chinese adults
- (2016) Gaokun Qiu et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Maintenance of Cognitive Performance and Mood for Individuals with Alzheimer’s Disease Following Consumption of a Nutraceutical Formulation: A One-Year, Open-Label Study
- (2016) Ruth Remington et al. JOURNAL OF ALZHEIMERS DISEASE
- Novel Molecular Interactions of Acylcarnitines and Fatty Acids with Myoglobin
- (2016) Sree V. Chintapalli et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Liver and Muscle Contribute Differently to the Plasma Acylcarnitine Pool During Fasting and Exercise in Humans
- (2016) G. Xu et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Faecal and serum metabolomics in paediatric inflammatory bowel disease
- (2016) Kaija-Leena Kolho et al. Journal of Crohns & Colitis
- Genotype and phenotype characterization in a Spanish cohort with isovaleric acidemia
- (2016) María L Couce et al. JOURNAL OF HUMAN GENETICS
- Short- and medium-chain fatty acids in energy metabolism: the cellular perspective
- (2016) Peter Schönfeld et al. JOURNAL OF LIPID RESEARCH
- Prognostic Implications of Long-Chain Acylcarnitines in Heart Failure and Reversibility With Mechanical Circulatory Support
- (2016) Tariq Ahmad et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Fatty acid oxidation in macrophage polarization
- (2016) Mitsunori Nomura et al. NATURE IMMUNOLOGY
- Acylcarnitines participate in developmental processes associated to lipid metabolism in plants
- (2016) Phuong-Jean Nguyen et al. PLANTA
- Acetyl-L-carnitine (ALCAR) to enhance nerve regeneration in carpal tunnel syndrome: study protocol for a randomized, placebo-controlled trial
- (2016) Matthew W. T. Curran et al. Trials
- A prospective study to evaluate the efficacy and safety of oral acetyl-L-carnitine for the treatment of chemotherapy-induced peripheral neuropathy
- (2016) Yuanjue Sun et al. Experimental and Therapeutic Medicine
- Effects of acetyl-L-carnitine and methylcobalamin for diabetic peripheral neuropathy: A multicenter, randomized, double-blind, controlled trial
- (2016) Sheyu Li et al. Journal of Diabetes Investigation
- Identification of candidate diagnostic biomarkers for adolescent idiopathic scoliosis using UPLC/QTOF-MS analysis: a first report of lipid metabolism profiles
- (2016) Zhi-jian Sun et al. Scientific Reports
- Hepatic Fatty Acid Oxidation Restrains Systemic Catabolism during Starvation
- (2016) Jieun Lee et al. Cell Reports
- Metabolomic Profiling Identifies Novel Circulating Biomarkers of Mitochondrial Dysfunction Differentially Elevated in Heart Failure With Preserved Versus Reduced Ejection Fraction: Evidence for Shared Metabolic Impairments in Clinical Heart Failure
- (2016) Wynn G. Hunter et al. Journal of the American Heart Association
- The Efficacy of Medical Treatment of Peyronie's Disease: Potassium Para-Aminobenzoate Monotherapyvs.Combination Therapy with Tamoxifen, L-Carnitine, and Phosphodiesterase Type 5 Inhibitor
- (2016) Tae Yong Park et al. World Journal of Mens Health
- Screening of Free Carnitine and Acylcarnitine Status in Children With Familial Mediterranean Fever
- (2016) Ertuğrul Kıykım Archives of Rheumatology
- Comparative Safety of Pharmacologic Treatments for Persistent Depressive Disorder: A Systematic Review and Network Meta-Analysis
- (2016) Ramona Meister et al. PLoS One
- Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer's Dementia
- (2016) Adriana Cristofano et al. PLoS One
- C26:0-Carnitine Is a New Biomarker for X-Linked Adrenoleukodystrophy in Mice and Man
- (2016) Malu-Clair van de Beek et al. PLoS One
- Maternal Early Pregnancy Serum Metabolomics Profile and Abnormal Vaginal Bleeding as Predictors of Placental Abruption: A Prospective Study
- (2016) Bizu Gelaye et al. PLoS One
- Global metabolomic profiling targeting childhood obesity in the Hispanic population
- (2015) Nancy F Butte et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Improvement of regressive autism symptoms in a child withTMLHEdeficiency following carnitine supplementation
- (2015) Mark N. Ziats et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Transorgan fluxes in a porcine model reveal a central role for liver in acylcarnitine metabolism
- (2015) Marieke G. Schooneman et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Long-chain acylcarnitines activate cell stress and myokine release in C2C12 myotubes: calcium-dependent and -independent effects
- (2015) Colin S. McCoin et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation
- (2015) Maria Ida Malandrino et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- The role of sirtuins in cardiac disease
- (2015) Shouji Matsushima et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Inhibition of L-carnitine biosynthesis and transport by methyl-γ-butyrobetaine decreases fatty acid oxidation and protects against myocardial infarction
- (2015) E Liepinsh et al. BRITISH JOURNAL OF PHARMACOLOGY
- Acetyl Coenzyme A: A Central Metabolite and Second Messenger
- (2015) Federico Pietrocola et al. Cell Metabolism
- CE-MS-based serum fingerprinting to track evolution of type 2 diabetes mellitus
- (2015) Michal Ciborowski et al. ELECTROPHORESIS
- Acylcarnitines: potential implications for skeletal muscle insulin resistance
- (2015) Céline Aguer et al. FASEB JOURNAL
- Metabolic Disturbances Identified in Plasma Are Associated With Outcomes in Patients With Heart Failure
- (2015) Mei-Ling Cheng et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Increased oxidative stress in patients with 3-hydroxy-3-methylglutaric aciduria
- (2015) Mariana dos Santos Mello et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Acylcarnitines—old actors auditioning for new roles in metabolic physiology
- (2015) Colin S. McCoin et al. Nature Reviews Endocrinology
- Clinical outcome, biochemical and therapeutic follow-up in 14 Austrian patients with Long-Chain 3-Hydroxy Acyl CoA Dehydrogenase Deficiency (LCHADD)
- (2015) Daniela Karall et al. Orphanet Journal of Rare Diseases
- Impaired mitochondrial fat oxidation induces adaptive remodeling of muscle metabolism
- (2015) Shawna E. Wicks et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Long-chain acyl-CoA esters in metabolism and signaling: Role of acyl-CoA binding proteins
- (2015) Ditte Neess et al. PROGRESS IN LIPID RESEARCH
- Glutaric aciduria type 1 as a cause of dystonic cerebral palsy
- (2015) Sarar Mohamed et al. SAUDI MEDICAL JOURNAL
- A Heterozygous Missense Mutation in Adolescent-Onset Very Long-Chain Acyl-CoA Dehydrogenase Deficiency with Exercise-Induced Rhabdomyolysis
- (2015) Shin Hisahara et al. TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE
- Methyl-γ-butyrobetaine decreases levels of acylcarnitines and attenuates the development of atherosclerosis
- (2015) Reinis Vilskersts et al. VASCULAR PHARMACOLOGY
- Clinical features and MUT gene mutation spectrum in Chinese patients with isolated methylmalonic acidemia: identification of ten novel allelic variants
- (2015) Lian-Shu Han et al. World Journal of Pediatrics
- Association between Arterial Stiffness and Serum L-Octanoylcarnitine and Lactosylceramide in Overweight Middle-Aged Subjects: 3-Year Follow-Up Study
- (2015) Minjoo Kim et al. PLoS One
- Metabolomic Fingerprint of Heart Failure with Preserved Ejection Fraction
- (2015) Beshay N. Zordoky et al. PLoS One
- The Origin and Diversity of Cpt1 Genes in Vertebrate Species
- (2015) Mónica Lopes-Marques et al. PLoS One
- Catabolism of Branched Chain Amino Acids Contributes Significantly to Synthesis of Odd-Chain and Even-Chain Fatty Acids in 3T3-L1 Adipocytes
- (2015) Scott B. Crown et al. PLoS One
- Metabolomic prediction of fetal congenital heart defect in the first trimester
- (2014) Ray O. Bahado-Singh et al. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Acylcarnitines activate proinflammatory signaling pathways
- (2014) Jennifer M. Rutkowsky et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Acyl-CoA Metabolism and Partitioning
- (2014) Trisha J. Grevengoed et al. Annual Review of Nutrition
- Plasma acylcarnitines inadequately reflect tissue acylcarnitine metabolism
- (2014) Marieke G. Schooneman et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Fatty acid oxidation is dispensable for human macrophage IL-4-induced polarization
- (2014) Dmitry Namgaladze et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Metabolism of Very Long-Chain Fatty Acids: Genes and Pathophysiology
- (2014) Takayuki Sassa et al. Biomolecules & Therapeutics
- Acetyl-l-carnitine (ALCAR) for the prevention of chemotherapy-induced peripheral neuropathy in patients with relapsed or refractory multiple myeloma treated with bortezomib, doxorubicin and low-dose dexamethasone: a study from the Wisconsin Oncology Network
- (2014) Natalie Callander et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Downregulation of Carnitine Acyl-Carnitine Translocase by miRNAs 132 and 212 Amplifies Glucose-Stimulated Insulin Secretion
- (2014) Mufaddal S. Soni et al. DIABETES
- Management of Hyperglycemia in Type 2 Diabetes, 2015: A Patient-Centered Approach: Update to a Position Statement of the American Diabetes Association and the European Association for the Study of Diabetes
- (2014) Silvio E. Inzucchi et al. DIABETES CARE
- Human serum acylcarnitine profiles in different glucose tolerance states
- (2014) Xiuying Zhang et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Acetyl-L-Carnitine Supplementation During HCV Therapy With Pegylated Interferon-α2b Plus Ribavirin: Effect on Work Performance. A Randomized Clinical Trial
- (2014) Giulia Malaguarnera et al. Hepatitis Monthly
- Discovery and validation of urinary metabotypes for the diagnosis of hepatocellular carcinoma in West Africans
- (2014) Nimzing G. Ladep et al. HEPATOLOGY
- Malonyl CoA: A promising target for the treatment of cardiac disease
- (2014) Natasha Fillmore et al. IUBMB LIFE
- Glutaric Aciduria Type II Presenting as Myopathy and Rhabdomyolysis in a Teenager
- (2014) Manish Prasad et al. JOURNAL OF CHILD NEUROLOGY
- A HPLC-Q-TOF-MS-based urinary metabolomic approach to identification of potential biomarkers of metabolic syndrome
- (2014) Zhi-rui Yu et al. Journal of Huazhong University of Science and Technology-Medical Sciences
- Metabonomics of Human Colorectal Cancer: New Approaches for Early Diagnosis and Biomarker Discovery
- (2014) Yan Ni et al. JOURNAL OF PROTEOME RESEARCH
- Age-Related Increase in Alanine Aminotransferase Correlates with Elevated Levels of Plasma Amino Acids, Decanoylcarnitine, Lp-PLA2 Activity, Oxidative Stress, and Arterial Stiffness
- (2014) Saem Jung et al. JOURNAL OF PROTEOME RESEARCH
- Long-chain acylcarnitine content determines the pattern of energy metabolism in cardiac mitochondria
- (2014) Marina Makrecka et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Carnitine/acylcarnitine translocase and carnitine palmitoyltransferase 2 form a complex in the inner mitochondrial membrane
- (2014) Lara Console et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Cobalamin C Deficiency in an Adolescent With Altered Mental Status and Anorexia
- (2014) Maria H. Rahmandar et al. PEDIATRICS
- Effect of sleep deprivation on the human metabolome
- (2014) S. K. Davies et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Propionyl-L-Carnitine is Efficacious in Ulcerative Colitis Through its Action on the Immune Function and Microvasculature
- (2014) Maria Giovanna Scioli et al. Clinical and Translational Gastroenterology
- Long-Chain Acyl Coenzyme A Synthetase 1 Overexpression in Primary Cultured Schwann Cells Prevents Long Chain Fatty Acid-Induced Oxidative Stress and Mitochondrial Dysfunction
- (2013) Lucy M. Hinder et al. ANTIOXIDANTS & REDOX SIGNALING
- Metabolomics signature improves the prediction of cardiovascular events in elderly subjects
- (2013) S. Rizza et al. ATHEROSCLEROSIS
- Peroxisomes contribute to the acylcarnitine production when the carnitine shuttle is deficient
- (2013) Sara Violante et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Substrate specificity of human carnitine acetyltransferase: Implications for fatty acid and branched-chain amino acid metabolism
- (2013) Sara Violante et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Mitochondrial fatty acid oxidation alterations in heart failure, ischaemic heart disease and diabetic cardiomyopathy
- (2013) N Fillmore et al. BRITISH JOURNAL OF PHARMACOLOGY
- SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks
- (2013) Matthew J. Rardin et al. Cell Metabolism
- Measurement of succinyl-carnitine and methylmalonyl-carnitine on dried blood spot by liquid chromatography-tandem mass spectrometry
- (2013) Cristiano Rizzo et al. CLINICA CHIMICA ACTA
- Evaluating the effects of amantadin, modafinil and acetyl-l-carnitine on fatigue in multiple sclerosis – result of a pilot randomized, blind study
- (2013) Alenka Horvat Ledinek et al. CLINICAL NEUROLOGY AND NEUROSURGERY
- Metabolomic analyses of faeces reveals malabsorption in cirrhotic patients
- (2013) Hai-jun Huang et al. DIGESTIVE AND LIVER DISEASE
- l-Acetylcarnitine in dysthymic disorder in elderly patients: A double-blind, multicenter, controlled randomized study vs. fluoxetine
- (2013) Giuseppe Bersani et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Acetyl-L-carnitine: from a biological curiosity to a drug for the peripheral nervous system and beyond
- (2013) Marco Onofrj et al. Expert Review of Neurotherapeutics
- Effect of Propionyl-L-carnitine on a Background of Monitored Exercise in Patients With Claudication Secondary to Peripheral Artery Disease
- (2013) William R. Hiatt et al. Journal of Cardiopulmonary Rehabilitation and Prevention
- Why does Brain Metabolism not Favor Burning of Fatty Acids to Provide Energy? - Reflections on Disadvantages of the Use of Free Fatty Acids as Fuel for Brain
- (2013) Peter Schönfeld et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Measurement of free carnitine and acylcarnitines in plasma by HILIC-ESI-MS/MS without derivatization
- (2013) Minzhi Peng et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Randomized Double-Blind Placebo-Controlled Trial of Acetyl-L-Carnitine for the Prevention of Taxane-Induced Neuropathy in Women Undergoing Adjuvant Breast Cancer Therapy
- (2013) Dawn L. Hershman et al. JOURNAL OF CLINICAL ONCOLOGY
- A Placebo-Controlled Trial of Acetyl-L-Carnitine and α-Lipoic Acid in the Treatment of Bipolar Depression
- (2013) Brian P. Brennan et al. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
- The novel mutation p.Asp251Asn in the β-subunit of succinate-CoA ligase causes encephalomyopathy and elevated succinylcarnitine
- (2013) Elham Jaberi et al. JOURNAL OF HUMAN GENETICS
- Human Mild Traumatic Brain Injury Decreases Circulating Branched-Chain Amino Acids and Their Metabolite Levels
- (2013) Cameron B. Jeter et al. JOURNAL OF NEUROTRAUMA
- Metabonomics Identifies Serum Metabolite Markers of Colorectal Cancer
- (2013) Binbin Tan et al. JOURNAL OF PROTEOME RESEARCH
- Carnitine palmitoyltransferase II (CPT II) deficiency: Genotype–Phenotype analysis of 50 patients
- (2013) Pushpa Raj Joshi et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- The heart is better protected against myocardial infarction in the fed state compared to the fasted state
- (2013) Edgars Liepinsh et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Global and Targeted Metabolomics of Esophageal Squamous Cell Carcinoma Discovers Potential Diagnostic and Therapeutic Biomarkers
- (2013) Jing Xu et al. MOLECULAR & CELLULAR PROTEOMICS
- Activated peroxisomal fatty acid metabolism improves cardiac recovery in ischemia-reperfusion
- (2013) Edgars Liepinsh et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- A Double-Blind, Randomized Phase II Study to Evaluate the Safety and Efficacy of Acetyl-L-Carnitine in the Prevention of Sagopilone-Induced Peripheral Neuropathy
- (2013) M. Campone et al. ONCOLOGIST
- Hypothalamic Inhibition of Acetyl-CoA Carboxylase Stimulates Hepatic Counter-Regulatory Response Independent of AMPK Activation in Rats
- (2013) Gustavo A. Santos et al. PLoS One
- Serum Levels of Acylcarnitines Are Altered in Prediabetic Conditions
- (2013) Manuel Mai et al. PLoS One
- An Integrated Clinico-Metabolomic Model Improves Prediction of Death in Sepsis
- (2013) R. J. Langley et al. Science Translational Medicine
- A study on the efficacy and safety assessment of Propionyl-L-carnitine tablets in treatment of intermittent claudication
- (2013) Tao Luo et al. THROMBOSIS RESEARCH
- World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders, Part 1: Update 2013 on the acute and continuation treatment of unipolar depressive disorders
- (2013) Michael Bauer et al. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
- A Plasma Long‐Chain Acylcarnitine Predicts Cardiovascular Mortality in Incident Dialysis Patients
- (2013) Sahir Kalim et al. Journal of the American Heart Association
- Unique acyl-carnitine profiles are potential biomarkers for acquired mitochondrial disease in autism spectrum disorder
- (2013) R E Frye et al. Translational Psychiatry
- Baseline metabolomic profiles predict cardiovascular events in patients at risk for coronary artery disease
- (2012) Svati H. Shah et al. AMERICAN HEART JOURNAL
- The emerging role of acyl-CoA thioesterases and acyltransferases in regulating peroxisomal lipid metabolism
- (2012) Mary C. Hunt et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Propionyl-L-Carnitine Improves Endothelial Function, Microcirculation and Pain Management in Critical Limb Ischemia
- (2012) S. De Marchi et al. CARDIOVASCULAR DRUGS AND THERAPY
- Carnitine and Acylcarnitines
- (2012) Stephanie E. Reuter et al. CLINICAL PHARMACOKINETICS
- Acylcarnitines
- (2012) Marieke G. Schooneman et al. DIABETES
- Disturbed carnitine regulation in chronic heart failure — Increased plasma levels of palmitoyl-carnitine are associated with poor prognosis
- (2012) Thor Ueland et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- NOX2 up-regulation is associated with artery dysfunction in patients with peripheral artery disease
- (2012) Lorenzo Loffredo et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Ceramide Levels Regulated by Carnitine Palmitoyltransferase 1C Control Dendritic Spine Maturation and Cognition
- (2012) Patricia Carrasco et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Clinical and biological features at diagnosis in mitochondrial fatty acid beta-oxidation defects: a French pediatric study of 187 patients
- (2012) Julien Baruteau et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Children at risk of diabetes type 1. Treatment with acetyl-L-carnitine plus nicotinamide – Case reports
- (2012) Ivana Cristina Fernandez et al. JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
- Promising outcomes in glutaric aciduria type I patients detected by newborn screening
- (2012) Chee-Seng Lee et al. METABOLIC BRAIN DISEASE
- Biochemical, molecular, and clinical characteristics of children with short chain acyl-CoA dehydrogenase deficiency detected by newborn screening in California
- (2012) Natalie M. Gallant et al. MOLECULAR GENETICS AND METABOLISM
- Novel biomarkers for pre-diabetes identified by metabolomics
- (2012) Rui Wang-Sattler et al. Molecular Systems Biology
- Chronic acetyl-l-carnitine alters brain energy metabolism and increases noradrenaline and serotonin content in healthy mice
- (2012) Olav B. Smeland et al. NEUROCHEMISTRY INTERNATIONAL
- Childhood Obesity Is Associated with Changes in the Serum Metabolite Profile
- (2012) Simone Wahl et al. Obesity Facts
- Long-Chain Acylcarnitines Regulate the hERG Channel
- (2012) Fabio Ferro et al. PLoS One
- Randomised clinical trial: the efficacy and safety of propionyl-l-carnitine therapy in patients with ulcerative colitis receiving stable oral treatment
- (2011) T. L. Mikhailova et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Oral acetyl-l-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study
- (2011) Michele Malaguarnera et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Ultra-high performance liquid chromatography tandem mass spectrometry for comprehensive analysis of urinary acylcarnitines
- (2011) Azeret Zuniga et al. ANALYTICA CHIMICA ACTA
- Propionyl-L-carnitine, L-arginine and niacin in sexual medicine: a nutraceutical approach to erectile dysfunction
- (2011) D. Gianfrilli et al. ANDROLOGIA
- Changes in carnitine octanoyltransferase activity induce alteration in fatty acid metabolism
- (2011) Françoise Le Borgne et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Targeting fatty acid and carbohydrate oxidation — A novel therapeutic intervention in the ischemic and failing heart
- (2011) Jagdip S. Jaswal et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Clinical validation of cutoff target ranges in newborn screening of metabolic disorders by tandem mass spectrometry: A worldwide collaborative project
- (2011) David M S McHugh et al. GENETICS IN MEDICINE
- Metabolic profiling of urine in young obese men using ultra performance liquid chromatography and Q-TOF mass spectrometry (UPLC/Q-TOF MS)
- (2011) Cheng Wang et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- The Supplementation of Acetyl-l-Carnitine Decreases Fatigue and Increases Quality of Life in Patients with Hepatitis C Treated with Pegylated Interferon-α 2b Plus Ribavirin
- (2011) Michele Malaguarnera et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Urinary Excretion of 3-Hydroxyisovaleryl Carnitine Is an Early and Sensitive Indicator of Marginal Biotin Deficiency in Humans
- (2011) Shawna L. Stratton et al. JOURNAL OF NUTRITION
- The effects of acute and prolonged CRAM supplementation on reaction time and subjective measures of focus and alertness in healthy college students
- (2011) Jay R Hoffman et al. Journal of the International Society of Sports Nutrition
- Postprandial changes in plasma acylcarnitine concentrations as markers of fatty acid flux in overweight and obesity
- (2011) Maria A. Ramos-Roman et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Characterization of D-3-hydroxybutyrylcarnitine (ketocarnitine): an identified ketosis-induced metabolite
- (2011) Maarten R. Soeters et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- The mitochondrial carnitine/acylcarnitine carrier: Function, structure and physiopathology
- (2011) Cesare Indiveri et al. MOLECULAR ASPECTS OF MEDICINE
- Characterization of oxaliplatin-induced chronic painful peripheral neuropathy in the rat and comparison with the neuropathy induced by paclitaxel
- (2011) W.H. Xiao et al. NEUROSCIENCE
- Acetyl-l-Carnitine in the treatment of anhedonia, melancholic and negative symptoms in alcohol dependent subjects
- (2011) Giovanni Martinotti et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Acetyl-l-carnitine reduces depression and improves quality of life in patients with minimal hepatic encephalopathy
- (2011) Mariano Malaguarnera et al. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
- Phytanic acid-an overlooked bioactive fatty acid in dairy fat?
- (2010) Lars I. Hellgren Annals of the New York Academy of Sciences
- How to use acylcarnitine profiles to help diagnose inborn errors of metabolism
- (2010) S. Santra et al. Archives of Disease in Childhood-Education and Practice Edition
- Carnitine palmitoyltransferase 2: New insights on the substrate specificity and implications for acylcarnitine profiling
- (2010) Sara Violante et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Association of a Peripheral Blood Metabolic Profile With Coronary Artery Disease and Risk of Subsequent Cardiovascular Events
- (2010) Svati H. Shah et al. Circulation-Cardiovascular Genetics
- Relationship of Octanoylcarnitine Concentrations to Age at Sampling in Unaffected Newborns Screened for Medium-Chain Acyl-CoA Dehydrogenase Deficiency
- (2010) J. M. Khalid et al. CLINICAL CHEMISTRY
- Ethylmalonic encephalopathy: application of improved biochemical and molecular diagnostic approaches
- (2010) A Drousiotou et al. CLINICAL GENETICS
- Fatty acid omega-oxidation as a rescue pathway for fatty acid oxidation disorders in humans
- (2010) Ronald J. A. Wanders et al. FEBS Journal
- Enzymology of the carnitine biosynthesis pathway
- (2010) Karin Strijbis et al. IUBMB LIFE
- Carnitine palmitoyl transferase activity and whole muscle oxidation rates vary with fatty acid substrate in avian flight muscles
- (2010) Edwin R. Price et al. JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY
- Long-chain acylcarnitine deficiency in patients with chronic fatigue syndrome. Potential involvement of altered carnitine palmitoyltransferase-I activity
- (2010) S. E. Reuter et al. JOURNAL OF INTERNAL MEDICINE
- A vitamin/nutriceutical formulation improves memory and cognitive performance in community-dwelling adults without dementia
- (2010) A. Chan et al. Journal of Nutrition Health & Aging
- Plasma metabolomic profile in nonalcoholic fatty liver disease
- (2010) Satish C. Kalhan et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Rapid determination of C4-acylcarnitine and C5-acylcarnitine isomers in plasma and dried blood spots by UPLC–MS/MS as a second tier test following flow-injection MS/MS acylcarnitine profile analysis
- (2010) Sabrina Forni et al. MOLECULAR GENETICS AND METABOLISM
- SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
- (2010) Matthew D. Hirschey et al. NATURE
- Increased Levels of Plasma Acylcarnitines in Obesity and Type 2 Diabetes and Identification of a Marker of Glucolipotoxicity
- (2010) Stephanie J. Mihalik et al. Obesity
- Succinyl-CoA Ligase Deficiency: A Mitochondrial Hepatoencephalomyopathy
- (2010) Johan L K Van Hove et al. PEDIATRIC RESEARCH
- Flavin Adenine Dinucleotide Status and the Effects of High-Dose Riboflavin Treatment in Short-Chain Acyl-CoA Dehydrogenase Deficiency
- (2010) Bianca T van Maldegem et al. PEDIATRIC RESEARCH
- Carnitine Palmitoyltransferase 2 Deficiency: The Time-Course of Blood and Urinary Acylcarnitine Levels during Initial L-Carnitine Supplementation
- (2010) Tomohiro Hori et al. TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE
- Malonylcarnitine in Newborns with Non‐syndromic Cleft Lip with or without Cleft Palate
- (2010) Kamil Konrad Hozyasz et al. International Journal of Oral Science
- Fat and Fatty Acid Terminology, Methods of Analysis and Fat Digestion and Metabolism: A Background Review Paper
- (2009) W.M. Nimal Ratnayake et al. ANNALS OF NUTRITION AND METABOLISM
- Modulation of the hepatic malonyl-CoA–carnitine palmitoyltransferase 1A partnership creates a metabolic switch allowing oxidation ofde novofatty acids1
- (2009) Marie Akkaoui et al. BIOCHEMICAL JOURNAL
- Mitochondrial long chain fatty acid β-oxidation in man and mouse
- (2009) Malika Chegary et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- A case of holocarboxylase synthetase deficiency with insufficient response to prenatal biotin therapy
- (2009) Kyoko Yokoi et al. BRAIN & DEVELOPMENT
- Structural insight into function and regulation of carnitine palmitoyltransferase
- (2009) Arne C. Rufer et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Thioctic Acid and Acetyl-L-Carnitine in the Treatment of Sciatic Pain Caused by a Herniated Disc
- (2009) Antonio Memeo et al. CLINICAL DRUG INVESTIGATION
- Effect of propionyl-l-carnitine,l-arginine and nicotinic acid on the efficacy of vardenafil in the treatment of erectile dysfunction in diabetes
- (2009) Vincenzo Gentile et al. CURRENT MEDICAL RESEARCH AND OPINION
- Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet-Induced Obese Mice Lacking Malonyl CoA Decarboxylase
- (2009) J. R. Ussher et al. DIABETES
- Acylcarnitine profile analysis
- (2009) Piero Rinaldo et al. GENETICS IN MEDICINE
- Acetyl-l-carnitine and nucleoside reverse transcriptase inhibitor-associated neuropathy in HIV infection
- (2009) V Valcour et al. HIV MEDICINE
- Effect ofL-Acetylcarnitine on Body Composition in HIV-related Lipodystrophy
- (2009) S. Benedini et al. HORMONE AND METABOLIC RESEARCH
- Ameliorating Hypertension and Insulin Resistance in Subjects at Increased Cardiovascular Risk
- (2009) Piero Ruggenenti et al. HYPERTENSION
- Carnitine Insufficiency Caused by Aging and Overnutrition Compromises Mitochondrial Performance and Metabolic Control
- (2009) Robert C. Noland et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- False-positive newborn screening mimicking glutaric aciduria type I in infants with renal insufficiency
- (2009) Julia B. Hennermann et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Management and outcome in 75 individuals with long-chain fatty acid oxidation defects: results from a workshop
- (2009) U. Spiekerkoetter et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Plasma Acylcarnitine Profiles Suggest Incomplete Long-Chain Fatty Acid β-Oxidation and Altered Tricarboxylic Acid Cycle Activity in Type 2 Diabetic African-American Women
- (2009) Sean H. Adams et al. JOURNAL OF NUTRITION
- Cytoprotective Effect of Acetyl-l-Carnitine Evidenced by Analysis of Gene Expression in the Rat Brain
- (2009) Giovanna Traina et al. MOLECULAR NEUROBIOLOGY
- Diagnostic assessment and long-term follow-up of 13 patients with Very Long-Chain Acyl-Coenzyme A dehydrogenase (VLCAD) deficiency
- (2009) Pascal Laforêt et al. NEUROMUSCULAR DISORDERS
- Acylcarnitines: Role in brain
- (2009) Lauren L. Jones et al. PROGRESS IN LIPID RESEARCH
- Mitochondrial 2,4-dienoyl-CoA Reductase Deficiency in Mice Results in Severe Hypoglycemia with Stress Intolerance and Unimpaired Ketogenesis
- (2009) Ilkka J. Miinalainen et al. PLoS Genetics
- Efficacy of a Vitamin/Nutriceutical Formulation for Early-stage Alzheimer's Disease: A 1-year, Open-label Pilot Study With an 16-Month Caregiver Extension
- (2008) Amy Chan et al. American Journal of Alzheimers Disease and Other Dementias
- Efficacy of a Vitamin/Nutriceutical Formulation for Moderate-stage to Later-stage Alzheimer's disease: A Placebo-controlled Pilot Study
- (2008) Ruth Remington et al. American Journal of Alzheimers Disease and Other Dementias
- Carnitine-palmitoyltransferase 2 deficiency: Novel mutations and relevance of newborn screening
- (2008) Sabine Illsinger et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Different effects of palmitoyl-l-carnitine and palmitoyl-CoA on mitochondrial function in rat ventricular myocytes
- (2008) Hiromutsu Tominaga et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Importancia del diagnóstico precoz y el tratamiento temprano en el pronóstico de la aciduria glutárica tipo I
- (2008) M.L. Couce Pico et al. ANALES DE PEDIATRIA
- Carnitine Status in Early-Treated Children, Adolescents and Young Adults with Phenylketonuria on Low Phenylalanine Diets
- (2008) C. Weigel et al. ANNALS OF NUTRITION AND METABOLISM
- Propionyl-l-Carnitine in Leriche-Fontaine Stage II Peripheral Arterial Obstructive Disease
- (2008) Claudio Allegra et al. ANNALS OF VASCULAR SURGERY
- Mass spectrometric demonstration of the presence of liver carnitine palmitoyltransferase-I (CPT-I) in heart mitochondria of adult rats
- (2008) Anne M. Distler et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance
- (2008) Timothy R. Koves et al. Cell Metabolism
- Short- and medium-chain carnitine acyltransferases and acyl-CoA thioesterases in mouse provide complementary systems for transport of β-oxidation products out of peroxisomes
- (2008) M. A. K. Westin et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Urine acylcarnitine analysis by ESI–MS/MS: A new tool for the diagnosis of peroxisomal biogenesis disorders
- (2008) Guglielmo Duranti et al. CLINICA CHIMICA ACTA
- Acetyl-l-Carnitine in the Management of Pain During Methadone Withdrawal Syndrome
- (2008) Luigi Janiri et al. CLINICAL NEUROPHARMACOLOGY
- Muscle acylcarnitines during short-term fasting in lean healthy men
- (2008) Maarten R. Soeters et al. CLINICAL SCIENCE
- CPT1c Is Localized in Endoplasmic Reticulum of Neurons and Has Carnitine Palmitoyltransferase Activity
- (2008) Adriana Y. Sierra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Brain-specific carnitine palmitoyl-transferase-1c: role in CNS fatty acid metabolism, food intake, and body weight
- (2008) Michael J. Wolfgang et al. JOURNAL OF NEUROCHEMISTRY
- Development of a New Enzymatic Diagnosis Method for Very-long-chain Acyl-CoA Dehydrogenase Deficiency by Detecting 2-Hexadecenoyl-CoA Production and its Application in Tandem Mass Spectrometry-based Selective Screening and Newborn Screening in Japan
- (2008) Go Tajima et al. PEDIATRIC RESEARCH
- Determination of the reference range of endogenous plasma carnitines in healthy adults
- (2008) S. E Reuter et al. ANNALS OF CLINICAL BIOCHEMISTRY
- Acetyl l-carnitine (ALC) treatment in elderly patients with fatigue
- (2007) Michele Malaguarnera et al. ARCHIVES OF GERONTOLOGY AND GERIATRICS
- Determination of 3-hydroxyisovalerylcarnitine and other acylcarnitine levels using liquid chromatography–tandem mass spectrometry in serum and urine of a patient with multiple carboxylase deficiency
- (2007) Yasuhiro Maeda et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Chemotherapy-evoked neuropathic pain: Abnormal spontaneous discharge in A-fiber and C-fiber primary afferent neurons and its suppression by acetyl-l-carnitine
- (2007) Wen Hua Xiao et al. PAIN
- The role of inflammation in CNS injury and disease
- (2006) Sian-Marie Lucas et al. BRITISH JOURNAL OF PHARMACOLOGY
- Functional relevance of carnitine transporter OCTN2 to brain distribution of l-carnitine and acetyl-l-carnitine across the blood-brain barrier
- (2003) Yasuto Kido et al. JOURNAL OF NEUROCHEMISTRY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started