Malonyl CoA: A promising target for the treatment of cardiac disease

Failing mouse hearts utilize energy inefficiently and benefit from improved coupling of glycolysis and glucose oxidation

(2013) Waleed G.T. Masoud et al.   CARDIOVASCULAR RESEARCH

Inhibition of malonyl-CoA decarboxylase reduces the inflammatory response associated with insulin resistance

(2012) Victor Samokhvalov et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Cardiac hypertrophy in the newborn delays the maturation of fatty acid β-oxidation and compromises postischemic functional recovery

(2012) Tatsujiro Oka et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury

(2012) John R. Ussher et al.   CARDIOVASCULAR RESEARCH

Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload

(2012) Pavel Zhabyeyev et al.   CARDIOVASCULAR RESEARCH

Cardiac-Specific Deletion of Acetyl CoA Carboxylase 2 Prevents Metabolic Remodeling During Pressure-Overload Hypertrophy

(2012) Stephen C. Kolwicz et al.   CIRCULATION RESEARCH

Dietary Fat and Heart Failure: Moving From Lipotoxicity to Lipoprotection

(2012) William C. Stanley et al.   CIRCULATION RESEARCH

Targeting fatty acid and carbohydrate oxidation — A novel therapeutic intervention in the ischemic and failing heart

(2011) Jagdip S. Jaswal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation

(2010) Liyan Zhang et al.   CARDIOVASCULAR RESEARCH

Analysis of Metabolic Remodeling in Compensated Left Ventricular Hypertrophy and Heart Failure

(2010) Takao Kato et al.   Circulation-Heart Failure

Energy Metabolic Phenotype of the Cardiomyocyte During Development, Differentiation, and Postnatal Maturation

(2010) Gary D Lopaschuk et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Intracerebroventricular Leptin Administration Differentially Alters Cardiac Energy Metabolism in Mice Fed a Low-fat and High-fat Diet

(2010) Wendy Keung et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Myocardial Fatty Acid Metabolism in Health and Disease

(2010) Gary D. Lopaschuk et al.   PHYSIOLOGICAL REVIEWS

Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet-Induced Obese Mice Lacking Malonyl CoA Decarboxylase

(2009) J. R. Ussher et al.   DIABETES

High rates of residual fatty acid oxidation during mild ischemia decrease cardiac work and efficiency

(2009) Clifford D.L. Folmes et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cellular fatty acid uptake: a pathway under construction

(2009) Xiong Su et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Reduced heart size and increased myocardial fuel substrate oxidation in ACC2 mutant mice

(2008) M. Faadiel Essop et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY