标题
Nuclear speckles – a driving force in gene expression
作者
关键词
-
出版物
JOURNAL OF CELL SCIENCE
Volume 135, Issue 13, Pages -
出版商
The Company of Biologists
发表日期
2022-07-05
DOI
10.1242/jcs.259594
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Gene architecture directs splicing outcome in separate nuclear spatial regions
- (2022) Luna Tammer et al. MOLECULAR CELL
- Systematic mapping of nuclear domain-associated transcripts reveals speckles and lamina as hubs of functionally distinct retained introns
- (2022) A. Rasim Barutcu et al. MOLECULAR CELL
- Dynamic regulation of CTCF stability and sub-nuclear localization in response to stress
- (2021) Bettina J. Lehman et al. PLoS Genetics
- Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome
- (2021) J. Yuyang Lu et al. CELL RESEARCH
- Integrated spatial genomics reveals global architecture of single nuclei
- (2021) Yodai Takei et al. NATURE
- Ligand effects on phase separation of multivalent macromolecules
- (2021) Kiersten M. Ruff et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Diagnostic, prognostic, and therapeutic significance of long non-coding RNA MALAT1 in cancer
- (2021) Bela Goyal et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- USP42 drives nuclear speckle mRNA splicing via directing dynamic phase separation to promote tumorigenesis
- (2021) Shuyan Liu et al. CELL DEATH AND DIFFERENTIATION
- p53 mediates target gene association with nuclear speckles for amplified RNA expression
- (2021) Katherine A. Alexander et al. MOLECULAR CELL
- Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components
- (2021) Evan Lester et al. NEURON
- Single-cell measurement of higher-order 3D genome organization with scSPRITE
- (2021) Mary V. Arrastia et al. NATURE BIOTECHNOLOGY
- Distinct nuclear compartment-associated genome architecture in the developing mammalian brain
- (2021) Sajad Hamid Ahanger et al. NATURE NEUROSCIENCE
- Nuclear compartmentalization as a mechanism of quantitative control of gene expression
- (2021) Prashant Bhat et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- ZFC3H1 prevents RNA trafficking into nuclear speckles through condensation
- (2021) Yimin Wang et al. NUCLEIC ACIDS RESEARCH
- The Effector Domain of the Influenza A Virus Nonstructural Protein NS1 Triggers Host Shutoff by Mediating Inhibition and Global Deregulation of Host Transcription When Associated with Specific Structures in the Nucleus
- (2021) Wolfgang Nacken et al. mBio
- Subcellular localization of biomolecules and drug distribution by high-definition ion beam imaging
- (2021) Xavier Rovira-Clavé et al. Nature Communications
- Pathological tau drives ectopic nuclear speckle scaffold protein SRRM2 accumulation in neuron cytoplasm in Alzheimer’s disease
- (2021) Pamela J. McMillan et al. Acta Neuropathologica Communications
- RNA promotes the formation of spatial compartments in the nucleus
- (2021) Sofia A. Quinodoz et al. CELL
- Phosphorylation regulates arginine-rich RNA-binding protein solubility and oligomerization
- (2021) Sean R. Kundinger et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cell-type specialization is encoded by specific chromatin topologies
- (2021) Warren Winick-Ng et al. NATURE
- Revealing RCOR2 as a regulatory component of nuclear speckles
- (2021) Carlos Rivera et al. Epigenetics & Chromatin
- Infection-induced chromatin modifications facilitate translocation of herpes simplex virus capsids to the inner nuclear membrane
- (2021) Vesa Aho et al. PLoS Pathogens
- Speckles and paraspeckles coordinate to regulate HSV-1 genes transcription
- (2021) Kun Li et al. Communications Biology
- Arginine-Enriched Mixed-Charge Domains Provide Cohesion for Nuclear Speckle Condensation
- (2020) Jamie A. Greig et al. MOLECULAR CELL
- Radial Organization in the Mammalian Nucleus
- (2020) Nicola Crosetto et al. Frontiers in Genetics
- Human papillomavirus type 16 infection activates the host serine arginine protein kinase 1 (SRPK1) – splicing factor axis
- (2020) Sarah Mole et al. JOURNAL OF GENERAL VIROLOGY
- GPSeq reveals the radial organization of chromatin in the cell nucleus
- (2020) Gabriele Girelli et al. NATURE BIOTECHNOLOGY
- The Role of Liquid–Liquid Phase Separation in the Compartmentalization of Cell Nucleus and Spatial Genome Organization
- (2020) S. V. Razin et al. BIOCHEMISTRY-MOSCOW
- Speculating on the Roles of Nuclear Speckles: How RNA‐Protein Nuclear Assemblies Affect Gene Expression
- (2020) Sarah E. Hasenson et al. BIOESSAYS
- Nuclear hubs built on RNAs and clustered organization of the genome
- (2020) Kelly P. Smith et al. CURRENT OPINION IN CELL BIOLOGY
- Tyramide signal amplification mass spectrometry (TSA-MS) ratio identifies nuclear speckle proteins
- (2020) Joseph Dopie et al. JOURNAL OF CELL BIOLOGY
- 3D mapping and accelerated super-resolution imaging of the human genome using in situ sequencing
- (2020) Huy Q. Nguyen et al. NATURE METHODS
- Nuclear export of chimeric mRNAs depends on an lncRNA-triggered autoregulatory loop in blood malignancies
- (2020) Zhen-Hua Chen et al. Cell Death & Disease
- Multiplexed imaging of nucleome architectures in single cells of mammalian tissue
- (2020) Miao Liu et al. Nature Communications
- HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains
- (2020) Ashwanth C. Francis et al. Nature Communications
- The Role of RNA Splicing Factors in Cancer: Regulation of Viral and Human Gene Expression in Human Papillomavirus-Related Cervical Cancer
- (2020) Andrea Cerasuolo et al. Frontiers in Cell and Developmental Biology
- SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses
- (2020) Abhik K. Banerjee et al. CELL
- Genome-Scale Imaging of the 3D Organization and Transcriptional Activity of Chromatin
- (2020) Jun-Han Su et al. CELL
- Role of SARS-CoV-2 in Altering the RNA-Binding Protein and miRNA-Directed Post-Transcriptional Regulatory Networks in Humans
- (2020) Rajneesh Srivastava et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- SON and SRRM2 are essential for nuclear speckle formation
- (2020) İbrahim Avşar Ilik et al. eLife
- The Sub-Nuclear Localization of RNA-Binding Proteins in KSHV-Infected Cells
- (2020) Ella Alkalay et al. Cells
- Clustering and reverse transcription of HIV‐1 genomes in nuclear niches of macrophages
- (2020) Elena Rensen et al. EMBO JOURNAL
- TSA-seq reveals a largely conserved genome organization relative to nuclear speckles with small position changes tightly correlated with gene expression changes
- (2020) Liguo Zhang et al. GENOME RESEARCH
- Splicing at the phase-separated nuclear speckle interface: a model
- (2020) Susan E Liao et al. NUCLEIC ACIDS RESEARCH
- Uncoupling of nucleo-cytoplasmic RNA export and localization during stress
- (2019) Hodaya Hochberg-Laufer et al. NUCLEIC ACIDS RESEARCH
- Nuclear speckle fusion via long-range directional motion regulates speckle morphology after transcriptional inhibition
- (2019) Jiah Kim et al. JOURNAL OF CELL SCIENCE
- Constitutive splicing and economies of scale in gene expression
- (2019) Fangyuan Ding et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Genome organization around nuclear speckles
- (2019) Yu Chen et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- U2 AF 65 assemblies drive sequence‐specific splice site recognition
- (2019) Manel Tari et al. EMBO REPORTS
- Disruption of nuclear speckles reduces chromatin interactions in active compartments
- (2019) Shibin Hu et al. Epigenetics & Chromatin
- Pol II phosphorylation regulates a switch between transcriptional and splicing condensates
- (2019) Yang Eric Guo et al. NATURE
- The liquid nucleome – phase transitions in the nucleus at a glance
- (2019) Amy R. Strom et al. JOURNAL OF CELL SCIENCE
- Molecular Mechanism of SR Protein Kinase 1 Inhibition by the Herpes Virus Protein ICP27
- (2019) Richard B. Tunnicliffe et al. mBio
- Availability of splicing factors in the nucleoplasm can regulate the release of mRNA from the gene after transcription
- (2019) Hodaya Hochberg-Laufer et al. PLoS Genetics
- Methods for mapping 3D chromosome architecture
- (2019) Rieke Kempfer et al. NATURE REVIEWS GENETICS
- Stress Granule Assembly Disrupts Nucleocytoplasmic Transport
- (2018) Ke Zhang et al. CELL
- Higher-Order Inter-chromosomal Hubs Shape 3D Genome Organization in the Nucleus
- (2018) Sofia A. Quinodoz et al. CELL
- Nuclear phosphatidylinositol 4,5-bisphosphate islets contribute to efficient RNA polymerase II-dependent transcription
- (2018) Margarita Sobol et al. JOURNAL OF CELL SCIENCE
- Kaposi's Sarcoma-Associated Herpesvirus mRNA Accumulation in Nuclear Foci Is Influenced by Viral DNA Replication and Viral Noncoding Polyadenylated Nuclear RNA
- (2018) Tenaya K. Vallery et al. JOURNAL OF VIROLOGY
- High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies
- (2018) Ji-Young Youn et al. MOLECULAR CELL
- mRNAs are sorted for export or degradation before passing through nuclear speckles
- (2018) Jing Fan et al. NUCLEIC ACIDS RESEARCH
- Intronless mRNAs transit through nuclear speckles to gain export competence
- (2018) Ke Wang et al. JOURNAL OF CELL BIOLOGY
- Mapping 3D genome organization relative to nuclear compartments using TSA-Seq as a cytological ruler
- (2018) Yu Chen et al. JOURNAL OF CELL BIOLOGY
- A Cytoplasmic RNA Virus Alters the Function of the Cell Splicing Protein SRSF2
- (2017) Efraín E. Rivera-Serrano et al. JOURNAL OF VIROLOGY
- RNA phase transitions in repeat expansion disorders
- (2017) Ankur Jain et al. NATURE
- Biomolecular condensates: organizers of cellular biochemistry
- (2017) Salman F. Banani et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Nuclear speckles: molecular organization, biological function and role in disease
- (2017) Lukasz Galganski et al. NUCLEIC ACIDS RESEARCH
- Reduction of Huntington’s Disease RNA Foci by CAG Repeat-Targeting Reagents
- (2017) Martyna O. Urbanek et al. Frontiers in Cellular Neuroscience
- Chromatin organization regulates viral egress dynamics
- (2017) Vesa Aho et al. Scientific Reports
- Three-dimensional genome architecture and emerging technologies: looping in disease
- (2017) Arpit Mishra et al. Genome Medicine
- Nuclear speckles are detention centers for transcripts containing expanded CAG repeats
- (2016) Martyna O. Urbanek et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Prognostic value of a newly identified MALAT1 alternatively spliced transcript in breast cancer
- (2016) Didier Meseure et al. BRITISH JOURNAL OF CANCER
- Mechanisms and Consequences of Macromolecular Phase Separation
- (2016) Louis-Philippe Bergeron-Sandoval et al. CELL
- Higher‐order oligomerization promotes localization of SPOP to liquid nuclear speckles
- (2016) Melissa R Marzahn et al. EMBO JOURNAL
- Serine/Arginine-rich Splicing Factor 2 Modulates Herpes Simplex Virus Type 1 Replication via Regulating Viral Gene Transcriptional Activity and Pre-mRNA Splicing
- (2016) Ziqiang Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts
- (2016) Nicola Meola et al. MOLECULAR CELL
- Influenza virus mRNA trafficking through host nuclear speckles
- (2016) Amir Mor et al. Nature Microbiology
- Coordinated Dynamics of RNA Splicing Speckles in the Nucleus
- (2015) Qiao Zhang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Human Papillomavirus 16 Oncoprotein Expression Is Controlled by the Cellular Splicing Factor SRSF2 (SC35)
- (2015) Melanie McFarlane et al. JOURNAL OF VIROLOGY
- Cadmium–cysteine coordination in the BK inner pore region and its structural and functional implications
- (2015) Yu Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nuclear Retention of mRNA in Mammalian Tissues
- (2015) Keren Bahar Halpern et al. Cell Reports
- Liquid-Liquid Phase Separation in Biology
- (2014) Anthony A. Hyman et al. Annual Review of Cell and Developmental Biology
- A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
- (2014) Suhas S.P. Rao et al. CELL
- Whole-genome screening identifies proteins localized to distinct nuclear bodies
- (2013) Ka-wing Fong et al. JOURNAL OF CELL BIOLOGY
- DNA Virus Replication Compartments
- (2013) M. Schmid et al. JOURNAL OF VIROLOGY
- Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic
- (2013) Youn-Bok Lee et al. Cell Reports
- SRSF1 regulates the assembly of pre-mRNA processing factors in nuclear speckles
- (2012) Vidisha Tripathi et al. MOLECULAR BIOLOGY OF THE CELL
- The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation
- (2012) Olga Anczuków et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Malat1 is not an essential component of nuclear speckles in mice
- (2012) S. Nakagawa et al. RNA
- Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion
- (2012) Cyrille Girard et al. Nature Communications
- ncRNA- and Pc2 Methylation-Dependent Gene Relocation between Nuclear Structures Mediates Gene Activation Programs
- (2011) Liuqing Yang et al. CELL
- Nucleation of nuclear bodies by RNA
- (2011) Sergey P. Shevtsov et al. NATURE CELL BIOLOGY
- Herpesviral replication compartments move and coalesce at nuclear speckles to enhance export of viral late mRNA
- (2011) L. Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The In Vivo Kinetics of RNA Polymerase II Elongation during Co-Transcriptional Splicing
- (2011) Yehuda Brody et al. PLOS BIOLOGY
- Association of adipogenic genes with SC-35 domains during porcine adipogenesis
- (2010) Izabela Szczerbal et al. CHROMOSOME RESEARCH
- Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients
- (2010) Chantal Sellier et al. EMBO JOURNAL
- Hsp70 gene association with nuclear speckles is Hsp70 promoter specific
- (2010) Yan Hu et al. JOURNAL OF CELL BIOLOGY
- Son Is Essential for Nuclear Speckle Organization and Cell Cycle Progression
- (2010) Alok Sharma et al. MOLECULAR BIOLOGY OF THE CELL
- SR proteins SRp20 and 9G8 contribute to efficient export of herpes simplex virus 1 mRNAs
- (2010) Laurimar Escudero-Paunetto et al. VIROLOGY
- Nuclear Speckles
- (2010) D. L. Spector et al. Cold Spring Harbor Perspectives in Biology
- A role for TREX components in the release of spliced mRNA from nuclear speckle domains
- (2010) Anusha P. Dias et al. Nature Communications
- Initial Genomics of the Human Nucleolus
- (2010) Attila Németh et al. PLoS Genetics
- Large-scale chromatin structure of inducible genes: transcription on a condensed, linear template
- (2009) Yan Hu et al. JOURNAL OF CELL BIOLOGY
- Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome
- (2009) E. Lieberman-Aiden et al. SCIENCE
- Genome-Wide Analysis of Histidine Repeats Reveals Their Role in the Localization of Human Proteins to the Nuclear Speckles Compartment
- (2009) Eulàlia Salichs et al. PLoS Genetics
- Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions
- (2008) Lars Guelen et al. NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More