Acute hypoxia promotes the liver angiogenesis of largemouth bass (Micropterus salmoides) by HIF - Dependent pathway

Endothelial TRPV4 channels prevent tumor growth and metastasis via modulation of tumor angiogenesis and vascular integrity

(2021) Anantha K. Kanugula et al.   ANGIOGENESIS

Hypoxia conditioned mesenchymal stem cell-derived extracellular vesicles induce increased in vitro vascular tube formation

(2021) C. Almeria et al.   CYTOTHERAPY

The role of mediating factors involved in angiogenesis during implantation

(2021) Lidia Boldeanu et al.   Romanian Journal of Morphology and Embryology

Editorial: How Do Metabolism, Angiogenesis, and Hypoxia Modulate Resistance?

(2021) Hiroshi Kondoh et al.   Frontiers in Oncology

Matrix Metalloproteinases and Arterial Hypertension: Role of Oxidative Stress and Nitric Oxide in Vascular Functional and Structural Alterations

(2021) Alejandro F. Prado et al.   Biomolecules

Regulation of redox signaling in HIF‐1‐dependent tumor angiogenesis

(2021) Valeria Manuelli et al.   FEBS Journal

Hypoxia and HIF-1 as key regulators of gut microbiota and host interactions

(2021) Laís P. Pral et al.   TRENDS IN IMMUNOLOGY

The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling

(2021) Eui Jung Moon et al.   Nature Communications

Lactate Consumption via Cascaded Enzymes Combined VEGF siRNA for Synergistic Anti‐Proliferation and Anti‐Angiogenesis Therapy of Tumors

(2021) Yan Tang et al.   Advanced Healthcare Materials

Altitude, Exercise, and Skeletal Muscle Angio-Adaptive Responses to Hypoxia: A Complex Story

(2021) Pierre Lemieux et al.   Frontiers in Physiology

Endothelial Dysfunction Driven by Hypoxia—The Influence of Oxygen Deficiency on NO Bioavailability

(2021) Anna Janaszak-Jasiecka et al.   Biomolecules

The heterogeneity of cancer endothelium: The relevance of angiogenesis and endothelial progenitor cells in cancer microenvironment

(2021) Giovanna Armani et al.   MICROVASCULAR RESEARCH

Matrine inhibits synovial angiogenesis in collagen-induced arthritis rats by regulating HIF-VEGF-Ang and inhibiting the PI3K/Akt signaling pathway

(2021) Limei Ao et al.   MOLECULAR IMMUNOLOGY

Lactate in the tumour microenvironment: From immune modulation to therapy

(2021) Zi-Hao Wang et al.   EBioMedicine

Combined exposure to hypoxia and ammonia aggravated biological effects on glucose metabolism, oxidative stress, inflammation and apoptosis in largemouth bass (Micropterus salmoides)

(2020) Liulan Zhao et al.   AQUATIC TOXICOLOGY

Vitamin C decreases VEGF expression levels via hypoxia‑inducible factor‑1α dependent and independent pathways in lens epithelial cells

(2020) Lin Zhao et al.   Molecular Medicine Reports

Novel Therapeutic Targets for Hypoxia-Related Cardiovascular Diseases: The Role of HIF-1

(2020) Minxuan Liu et al.   Frontiers in Physiology

Label-free sensing of exosomal MCT1 and CD147 for tracking metabolic reprogramming and malignant progression in glioma

(2020) A. Thakur et al.   Science Advances

MiRNA-mRNA integration analysis reveals the regulatory roles of miRNAs in the metabolism of largemouth bass (Micropterus salmoides) livers during acute hypoxic stress

(2020) Jun Long Sun et al.   AQUACULTURE

MiR-221-3p targets Hif-1α to inhibit angiogenesis in heart failure

(2020) Yuying Li et al.   LABORATORY INVESTIGATION

NO-induced vasodilation correlates directly with BP in smooth muscle-Na/Ca exchanger-1-engineered mice: elevated BP does not attenuate endothelial function

(2020) Youhua Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Thrombospondin 1‐induced exosomal proteins attenuate hypoxia‐induced paraptosis in corneal epithelial cells and promote wound healing

(2020) Yu‐Hung Lai et al.   FASEB JOURNAL

Arterialization requires the timely suppression of cell growth

(2020) Wen Luo et al.   NATURE

Fish response to hypoxia stress: growth, physiological, and immunological biomarkers

(2019) Mohsen Abdel-Tawwab et al.   FISH PHYSIOLOGY AND BIOCHEMISTRY

VEGF in Signaling and Disease: Beyond Discovery and Development

(2019) Rajendra S. Apte et al.   CELL

Downregulation of endothelial transient receptor potential vanilloid type 4 channel underlines impaired endothelial nitric oxide-mediated relaxation in the mesenteric arteries of hypertensive rats

(2019) A. Boudaka et al.   PHYSIOLOGICAL RESEARCH

Response of AMP-activated protein kinase and lactate metabolism of largemouth bass (Micropterus salmoides) under acute hypoxic stress

(2019) S. Yang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

CDK5RAP3 inhibits angiogenesis in gastric neuroendocrine carcinoma by modulating AKT/HIF-1α/VEGFA signaling

(2019) Jian-Xian Lin et al.   Cancer Cell International

Acute hypoxia changes the mode of glucose and lipid utilization in the liver of the largemouth bass (Micropterus salmoides)

(2019) Jun Long Sun et al.   SCIENCE OF THE TOTAL ENVIRONMENT

MicroRNA-124 regulates lactate transportation in the muscle of largemouth bass (micropterus salmoides) under hypoxia by targeting MCT1

(2019) L.L. Zhao et al.   AQUATIC TOXICOLOGY

In utero hypoxia altered Ang II-induced contraction via PKCβ in fetal cerebral arteries

(2019) Hongyu Su et al.   JOURNAL OF ENDOCRINOLOGY

Lactate/GPR81 signaling and proton motive force in cancer: Role in angiogenesis, immune escape, nutrition, and Warburg phenomenon

(2019) Timothy P. Brown et al.   PHARMACOLOGY & THERAPEUTICS

Molecular Pharmacology of VEGF-A Isoforms: Binding and Signalling at VEGFR2

(2018) Chloe Peach et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Redox control of cancer cell destruction

(2018) Csaba Hegedűs et al.   Redox Biology

Inhibition of HIF-1α Reduced Blood Brain Barrier Damage by Regulating MMP-2 and VEGF During Acute Cerebral Ischemia

(2018) Yufei Shen et al.   Frontiers in Cellular Neuroscience

NGF increases FGF2 expression and promotes endothelial cell migration and tube formation through PI3K/Akt and ERK/MAPK pathways in human chondrocytes

(2018) X. Yu et al.   OSTEOARTHRITIS AND CARTILAGE

Convergence of VEGF and YAP/TAZ signaling: Implications for angiogenesis and cancer biology

(2018) Ameer L. Elaimy et al.   Science Signaling

Acute hypoxic stress: Effect on blood parameters, antioxidant enzymes, and expression of HIF-1alpha and GLUT-1 genes in largemouth bass ( Micropterus salmoides )

(2017) S. Yang et al.   FISH & SHELLFISH IMMUNOLOGY

Targeting Oxygen-Sensing Prolyl Hydroxylase for Metformin-Associated Lactic Acidosis Treatment

(2017) Tomoko Oyaizu-Toramaru et al.   MOLECULAR AND CELLULAR BIOLOGY

Classical VEGF, Notch and Ang signalling in cancer angiogenesis, alternative approaches and future directions

(2017) Nunzia Caporarello et al.   Molecular Medicine Reports

Organotypic vasculature: From descriptive heterogeneity to functional pathophysiology

(2017) Hellmut G. Augustin et al.   SCIENCE

Renal Protection Mediated by Hypoxia Inducible Factor-1α Depends on Proangiogenesis Function of miR-21 by Targeting Thrombospondin 1

(2017) Xialian Xu et al.   TRANSPLANTATION

Hypoxia in tissue repair and fibrosis

(2016) Ian A. Darby et al.   CELL AND TISSUE RESEARCH

Role of NRP-1 in VEGF-VEGFR2-Independent Tumorigenesis

(2016) Chenxi Hu et al.   Targeted Oncology

VEGFA splicing: divergent isoforms regulate spermatogonial stem cell maintenance

(2015) Kevin M. Sargent et al.   CELL AND TISSUE RESEARCH

Biology of Hypoxia

(2015) Paul N. Span et al.   SEMINARS IN NUCLEAR MEDICINE

Metformin suppresses hypoxia-induced stabilization of HIF-1α through reprogramming of oxygen metabolism in hepatocellular carcinoma

(2015) Xinke Zhou et al.   Oncotarget

VEGF, not VEGFR2, is associated with the angiogenesis effect of mini-TyrRS/mini-TrpRS in human umbilical vein endothelial cells in hypoxia

(2013) Rui Zeng et al.   CYTOTECHNOLOGY

Endothelial cell metabolism and tumour angiogenesis: glucose and glutamine as essential fuels and lactate as the driving force

(2013) F. Polet et al.   JOURNAL OF INTERNAL MEDICINE

Targeting the Lactate Transporter MCT1 in Endothelial Cells Inhibits Lactate-Induced HIF-1 Activation and Tumor Angiogenesis

(2012) Pierre Sonveaux et al.   PLoS One

Lactate Activates HIF-1 in Oxidative but Not in Warburg-Phenotype Human Tumor Cells

(2012) Christophe J. De Saedeleer et al.   PLoS One

Lactate Influx through the Endothelial Cell Monocarboxylate Transporter MCT1 Supports an NF- B/IL-8 Pathway that Drives Tumor Angiogenesis

(2011) F. Vegran et al.   CANCER RESEARCH

Hypoxia-induced oxidative DNA damage links with higher level biological effects including specific growth rate in common carp, Cyprinus carpio L.

(2011) Sanaa A. Mustafa et al.   ECOTOXICOLOGY

Integration of cardiovascular regulation by the blood/endothelium cell-free layer

(2011) C. Makena Hightower et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Hypoxia-induced expression of bradykinin type-2 receptors in endothelial cells triggers NO production, cell migration, and angiogenesis

(2009) Inka Liesmaa et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Kaempferol Inhibits Angiogenesis and VEGF Expression Through Both HIF Dependent and Independent Pathways in Human Ovarian Cancer Cells

(2009) Haitao Luo et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Modulation of Endothelium and Endothelial Progenitor Cell Function by Low-Density Lipoproteins: Implication for Vascular Repair, Angiogenesis and Vasculogenesis

(2009) Cristina Rodríguez et al.   PATHOBIOLOGY

Ang-1 Gene Therapy Inhibits Hypoxia-Inducible Factor-1  (HIF-1 )-Prolyl-4-Hydroxylase-2, Stabilizes HIF-1  Expression, and Normalizes Immature Vasculature in db/db Mice

(2008) J.-X. Chen et al.   DIABETES

Notch signaling regulates tumor angiogenesis by diverse mechanisms

(2008) J Dufraine et al.   ONCOGENE