Genome-wide meta-analysis and omics integration identifies novel genes associated with diabetic kidney disease

Assessment of differentially methylated loci in individuals with end-stage kidney disease attributed to diabetic kidney disease: an exploratory study

(2021) L. J. Smyth et al.   Clinical Epigenetics

A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis

(2021) Yuting Guan et al.   Nature Communications

Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals

(2021) Kira J. Stanzick et al.   Nature Communications

The GTEx Consortium atlas of genetic regulatory effects across human tissues

(2020)   SCIENCE

No causal effects of serum urate levels on the risk of chronic kidney disease: A Mendelian randomization study

(2019) Daniel M. Jordan et al.   PLOS MEDICINE

Changes in Albuminuria But Not GFR are Associated with Early Changes in Kidney Structure in Type 2 Diabetes

(2019) Helen C. Looker et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A catalog of genetic loci associated with kidney function from analyses of a million individuals

(2019) Matthias Wuttke et al.   NATURE GENETICS

Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen

(2019) Rany M. Salem et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The single-cell transcriptomic landscape of early human diabetic nephropathy

(2019) Parker C. Wilson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

(2019) Alexander Teumer et al.   Nature Communications

A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes

(2018) Natalie R. van Zuydam et al.   DIABETES

Risk of coronary artery disease and stroke according to sex and presence of diabetic nephropathy in type 1 diabetes

(2018) Valma Harjutsalo et al.   DIABETES OBESITY & METABOLISM

Lipoxins Regulate the Early Growth Response–1 Network and Reverse Diabetic Kidney Disease

(2018) Eoin P. Brennan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A molecular morphometric approach to diabetic kidney disease can link structure to function and outcome

(2018) Viji Nair et al.   KIDNEY INTERNATIONAL

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics

(2018) Alvaro N. Barbeira et al.   Nature Communications

The MR-Base platform supports systematic causal inference across the human phenome

(2018) Gibran Hemani et al.   eLife

An eQTL Landscape of Kidney Tissue in Human Nephrotic Syndrome

(2018) Christopher E. Gillies et al.   AMERICAN JOURNAL OF HUMAN GENETICS

NR4A1 Promotes Diabetic Nephropathy by Activating Mff-Mediated Mitochondrial Fission and Suppressing Parkin-Mediated Mitophagy

(2018) Junqin Sheng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Renal compartment–specific genetic variation analyses identify new pathways in chronic kidney disease

(2018) Chengxiang Qiu et al.   NATURE MEDICINE

The serum uric acid concentration is not causally linked to diabetic nephropathy in type 1 diabetes

(2017) Aila J. Ahola et al.   KIDNEY INTERNATIONAL

Rare and low-frequency coding variants alter human adult height

(2017) Eirini Marouli et al.   NATURE

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

(2016) Jack Bowden et al.   GENETIC EPIDEMIOLOGY

The Genetic Landscape of Renal Complications in Type 1 Diabetes

(2016) Niina Sandholm et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Fast and Rigorous Computation of Gene and Pathway Scores from SNP-Based Summary Statistics

(2016) David Lamparter et al.   PLoS Computational Biology

Genetic Evidence for a Causal Role of Obesity in Diabetic Kidney Disease

(2015) Jennifer N. Todd et al.   DIABETES

Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C

(2015) Borbala Mifsud et al.   NATURE GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND)

(2015) Sudha K. Iyengar et al.   PLoS Genetics

Genome-wide association study of urinary albumin excretion rate in patients with type 1 diabetes

(2014) Niina Sandholm et al.   DIABETOLOGIA

Akirin2 is critical for inducing inflammatory genes by bridging I B-  and the SWI/SNF complex

(2014) S. Tartey et al.   EMBO JOURNAL

Defining cell-type specificity at the transcriptional level in human disease

(2013) Wenjun Ju et al.   GENOME RESEARCH

Chromosome 2q31.1 Associates with ESRD in Women with Type 1 Diabetes

(2013) N. Sandholm et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

(2012) Benjamin F Voight et al.   LANCET

LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection

(2012) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes

(2012) Niina Sandholm et al.   PLoS Genetics

Transcriptome Analysis of Human Diabetic Kidney Disease

(2011) K. I. Woroniecka et al.   DIABETES

An intergenic region on chromosome 13q33.3 is associated with the susceptibility to kidney disease in type 1 and 2 diabetes

(2011) Marcus G. Pezzolesi et al.   KIDNEY INTERNATIONAL

The Presence and Severity of Chronic Kidney Disease Predicts All-Cause Mortality in Type 1 Diabetes

(2009) P.-H. Groop et al.   DIABETES

The Role of the Mammalian Target Of Rapamycin (mTOR) in Renal Disease

(2009) W. Lieberthal et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY