Targeting Ras-ERK cascade by bioactive natural products for potential treatment of cancer: an updated overview
出版年份 2022 全文链接
标题
Targeting Ras-ERK cascade by bioactive natural products for potential treatment of cancer: an updated overview
作者
关键词
-
出版物
Cancer Cell International
Volume 22, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-08-08
DOI
10.1186/s12935-022-02666-z
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Nutraceutical Profiling, Bioactive Composition, and Biological Applications of Lepidium sativum L.
- (2022) Sakshi Painuli et al. Oxidative Medicine and Cellular Longevity
- Neurobiological Promises of the Bitter Diterpene Lactone Andrographolide
- (2022) Rajib Hossain et al. Oxidative Medicine and Cellular Longevity
- Therapeutic Applications of Curcumin in Diabetes: A Review and Perspective
- (2022) Cristina Quispe et al. Biomed Research International
- Resveratrol’ biotechnological applications: enlightening its antimicrobial and antioxidant properties
- (2022) Javad Sharifi-Rad et al. Journal of Herbal Medicine
- Limonoids From the Genus Melia (Meliaceae): Phytochemistry, Synthesis, Bioactivities, Pharmacokinetics, and Toxicology
- (2022) Wenxiang Fan et al. Frontiers in Pharmacology
- Anticancer potential of alkaloids: a key emphasis to colchicine, vinblastine, vincristine, vindesine, vinorelbine and vincamine
- (2022) Praveen Dhyani et al. Cancer Cell International
- Natural products and synthetic analogues against HIV: A perspective to develop new potential anti-HIV drugs
- (2022) Jelena Popović-Djordjević et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Ethnobotany, Phytochemistry, Biological Activities, and Health-Promoting Effects of the Genus Bulbophyllum
- (2022) Javad Sharifi-Rad et al. Evidence-based Complementary and Alternative Medicine
- Urtica dioica-Derived Phytochemicals for Pharmacological and Therapeutic Applications
- (2022) Yasaman Taheri et al. Evidence-based Complementary and Alternative Medicine
- Diosgenin: An Updated Pharmacological Review and Therapeutic Perspectives
- (2022) Prabhakar Semwal et al. Oxidative Medicine and Cellular Longevity
- Pharmacological Properties of Bergapten: Mechanistic and Therapeutic Aspects
- (2022) Maria Magdalena Quetglas-Llabrés et al. Oxidative Medicine and Cellular Longevity
- Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
- (2022) Rajesh Sharma et al. Lancet Gastroenterology & Hepatology
- Autocrine TGF-β in Cancer: Review of the Literature and Caveats in Experimental Analysis
- (2021) Hendrik Ungefroren INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Properties of FDA-approved small molecule protein kinase inhibitors: a 2021 update
- (2021) Robert Roskoski PHARMACOLOGICAL RESEARCH
- Pharmacological Properties of Chalcones: A Review of Preclinical Including Molecular Mechanisms and Clinical Evidence
- (2021) Bahare Salehi et al. Frontiers in Pharmacology
- A Novel Nutraceutical Formulation Can Improve Motor Activity and Decrease the Stress Level in a Murine Model of Middle-Age Animals
- (2021) Dimitris Tsoukalas et al. Journal of Clinical Medicine
- Flavonoids as potential anti-platelet aggregation agents: from biochemistry to health promoting abilities
- (2021) Javad Sharifi-Rad et al. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
- Recent developments in mitogen activated protein kinase inhibitors as potential anticancer agents
- (2021) Vikram Jeet Singh et al. BIOORGANIC CHEMISTRY
- Chitosan nanoparticles as a promising tool in nanomedicine with particular emphasis on oncological treatment
- (2021) Javad Sharifi-Rad et al. Cancer Cell International
- A Pharmacological Perspective on Plant-derived Bioactive Molecules for Epilepsy
- (2021) Javad Sharifi-Rad et al. NEUROCHEMICAL RESEARCH
- Bioactive Compounds as Potential Agents for Sexually Transmitted Diseases Management: A Review to Explore Molecular Mechanisms of Action
- (2021) Javad Sharifi-Rad et al. Frontiers in Pharmacology
- Therapeutic Potential of Neoechinulins and Their Derivatives: An Overview of the Molecular Mechanisms Behind Pharmacological Activities
- (2021) Javad Sharifi-Rad et al. Frontiers in Nutrition
- Anti‐Lung Cancer Activities of 1,2,3‐Triazole Curcumin Derivatives via Regulation of the MAPK/NF‐κB/STAT3 Signaling Pathways
- (2021) Tai Xin Zhi et al. ChemMedChem
- In Silico Screening of Natural Products as Potential Inhibitors of SARS-CoV-2 Using Molecular Docking Simulation
- (2021) Rajib Hossain et al. Chinese Journal of Integrative Medicine
- Engineering Cancer Antigen-Specific T Cells to Overcome the Immunosuppressive Effects of TGF-β
- (2021) Jonathan D. Silk et al. JOURNAL OF IMMUNOLOGY
- Roles of Therapeutic Bioactive Compounds in Hepatocellular Carcinoma
- (2021) Divya Jain et al. Oxidative Medicine and Cellular Longevity
- A Literature-Based Update on Benincasa hispida (Thunb.) Cogn.: Traditional Uses, Nutraceutical, and Phytopharmacological Profiles
- (2021) Muhammad Torequl Islam et al. Oxidative Medicine and Cellular Longevity
- Tobacco Smoking and Liver Cancer Risk: Potential Avenues for Carcinogenesis
- (2021) Divya Jain et al. Journal of Oncology
- Escin induces apoptosis in ovarian cancer cell line by triggering S-phase cell cycle arrest and p38 MAPK/ERK pathway inhibition
- (2021) Wei Zhao et al. JOURNAL OF KING SAUD UNIVERSITY SCIENCE
- Amentoflavone, New Hope against SARS-CoV-2: An Outlook through its Scientific Records and an in silico Study
- (2021) Rajib Hossain et al. Pharmacognosy Research
- Targeting MAPK Signaling in Cancer: Mechanisms of Drug Resistance and Sensitivity
- (2020) Shannon Lee et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Erratum: microRNA Crosstalk Influences Epithelial-to-Mesenchymal, Endothelial-to-Mesenchymal, and Macrophage-to-Mesenchymal Transitions in the Kidney
- (2020) Frontiers in Pharmacology
- Avocado–Soybean Unsaponifiables: A Panoply of Potentialities to Be Exploited
- (2020) Bahare Salehi et al. Biomolecules
- ERK2 Phosphorylates PFAS to Mediate Posttranslational Control of De Novo Purine Synthesis
- (2020) Eunus S. Ali et al. MOLECULAR CELL
- The Treatment of Cognitive, Behavioural and Motor Impairments from Brain Injury and Neurodegenerative Diseases through Cannabinoid System Modulation—Evidence from In Vivo Studies
- (2020) Daniela Calina et al. Journal of Clinical Medicine
- Anticancer effects of Poncirus�fructus on hepatocellular carcinoma through regulation of apoptosis, migration, and invasion
- (2020) Suvesh Munakarmi et al. ONCOLOGY REPORTS
- Ficus plants: State of the art from a phytochemical, pharmacological, and toxicological perspective
- (2020) Bahare Salehi et al. PHYTOTHERAPY RESEARCH
- Targeting Ca2+ Signaling in the Initiation, Promotion and Progression of Hepatocellular Carcinoma
- (2020) Eunus S. Ali et al. Cancers
- Organ-on-a-Chip: A New Paradigm for Drug Development
- (2020) Chao Ma et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Inhibitory Effect of CAPE and Kaempferol in Colon Cancer Cell Lines—Possible Implications in New Therapeutic Strategies
- (2019) Liviuta Budisan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The importance of developing therapies targeting the biological spectrum of metastatic disease
- (2019) Andries Zijlstra et al. CLINICAL & EXPERIMENTAL METASTASIS
- The Function of Non-Coding RNAs in Lung Cancer Tumorigenesis
- (2019) Cornelia Braicu et al. Cancers
- Adaptation to chronic acidic extracellular pH elicits a sustained increase in lung cancer cell invasion and metastasis
- (2019) Shusaku Sutoo et al. CLINICAL & EXPERIMENTAL METASTASIS
- Resveratrol Activates Autophagy via the AKT/mTOR Signaling Pathway to Improve Cognitive Dysfunction in Rats With Chronic Cerebral Hypoperfusion
- (2019) Nan Wang et al. Frontiers in Neuroscience
- Tomatidine inhibits cell invasion through the negative modulation of gelatinase and inactivation of p38 and ERK
- (2019) Sojeong Jeon et al. CHEMICO-BIOLOGICAL INTERACTIONS
- A Comprehensive Review on MAPK: A Promising Therapeutic Target in Cancer
- (2019) Braicu et al. Cancers
- Oncogenic Signaling Pathways in The Cancer Genome Atlas
- (2018) Francisco Sanchez-Vega et al. CELL
- Delphinidin induces apoptosis and inhibits epithelial-to-mesenchymal transition via the ERK/p38 MAPK-signaling pathway in human osteosarcoma cell lines
- (2018) Hae-Mi Kang et al. ENVIRONMENTAL TOXICOLOGY
- Combined treatment with sorafenib and silibinin synergistically targets both HCC cells and cancer stem cells by enhanced inhibition of the phosphorylation of STAT3/ERK/AKT
- (2018) Jie Mao et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Luteoloside Inhibits Proliferation and Promotes Intrinsic and Extrinsic Pathway-Mediated Apoptosis Involving MAPK and mTOR Signaling Pathways in Human Cervical Cancer Cells
- (2018) Junli Shao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Toosendanin, a natural product, inhibited TGF-β1-induced epithelial-mesenchymal transition through ERK/Snail pathway
- (2018) Weiwei Luo et al. PHYTOTHERAPY RESEARCH
- Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy
- (2018) Feifei Liu et al. Acta Pharmaceutica Sinica B
- Magnolin targeting of ERK1/2 inhibits cell proliferation and colony growth by induction of cellular senescence in ovarian cancer cells
- (2018) Ji-Hong Song et al. MOLECULAR CARCINOGENESIS
- Isotrifoliol inhibits pro-inflammatory mediators by suppression of TLR/NF-κB and TLR/MAPK signaling in LPS-induced RAW264.7 cells
- (2017) Hua Li et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Dietary Intervention by Phytochemicals and Their Role in Modulating Coding and Non-Coding Genes in Cancer
- (2017) Liviuta Budisan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- 5,6,7,3′,4′,5′-Hexamethoxyflavone inhibits growth of triple-negative breast cancer cells via suppression of MAPK and Akt signaling pathways and arresting cell cycle
- (2017) Natasha Borah et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Naringenin-Induced Apoptotic Cell Death in Prostate Cancer Cells Is Mediated via the PI3K/AKT and MAPK Signaling Pathways
- (2017) Whasun Lim et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Nutrigenomics in cancer: Revisiting the effects of natural compounds
- (2017) Cornelia Braicu et al. SEMINARS IN CANCER BIOLOGY
- Arctigenin induced gallbladder cancer senescence through modulating epidermal growth factor receptor pathway
- (2017) Mingdi Zhang et al. TUMOR BIOLOGY
- Escin induces caspase-dependent apoptosis and autophagy through the ROS/p38 MAPK signalling pathway in human osteosarcoma cells in vitro and in vivo
- (2017) Jian Zhu et al. Cell Death & Disease
- Alpha-mangostin induces apoptosis through activation of reactive oxygen species and ASK1/p38 signaling pathway in cervical cancer cells
- (2017) Chien-Hsing Lee et al. Oncotarget
- Parthenolide suppresses non-small cell lung cancer GLC-82 cells growth via B-Raf/MAPK/Erk pathway
- (2017) Minting Lin et al. Oncotarget
- Genistein inhibits the growth and regulates the migration and invasion abilities of melanoma cells via the FAK/paxillin and MAPK pathways
- (2017) Shuna Cui et al. Oncotarget
- Deguelin, a Novel Anti-Tumorigenic Agent in Human Esophageal Squamous Cell Carcinoma
- (2017) Yuh Baba et al. EBioMedicine
- Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways
- (2017) et al. Cancers
- Fisetin inhibits laryngeal carcinoma through regulation of AKT/NF-κB/mTOR and ERK1/2 signaling pathways
- (2016) Xi-Jun Zhang et al. BIOMEDICINE & PHARMACOTHERAPY
- Cancer: A Problem of Developmental Biology; Scientific Evidence for Reprogramming and Differentiation Therapy
- (2016) Stewart Sell et al. CURRENT DRUG TARGETS
- Coumestrol Inhibits Proliferation and Migration of Prostate Cancer Cells by Regulating AKT, ERK1/2, and JNK MAPK Cell Signaling Cascades
- (2016) Whasun Lim et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Inhibitory Effects of Quercetin on Progression of Human Choriocarcinoma Cells Are Mediated Through PI3K/AKT and MAPK Signal Transduction Cascades
- (2016) Whasun Lim et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Apigenin Reduces Survival of Choriocarcinoma Cells by Inducing Apoptosis via the PI3K/AKT and ERK1/2 MAPK Pathways
- (2016) Whasun Lim et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Caffeic acid phenethyl ester activates pro-apoptotic and epithelial–mesenchymal transition-related genes in ovarian cancer cells A2780 and A2780cis
- (2016) Claudia Gherman et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- The effects of sulforaphane on canine osteosarcoma proliferation and invasion
- (2016) V. L. Rizzo et al. Veterinary and Comparative Oncology
- A natural small molecule, catechol, induces c-Myc degradation by directly targeting ERK2 in lung cancer
- (2016) Do Young Lim et al. Oncotarget
- Magnolin inhibits cell migration and invasion by targeting the ERKs/RSK2 signaling pathway
- (2015) Cheol-Jung Lee et al. BMC CANCER
- Expression profile of COL2A1 and the pseudogene SLC6A10P predicts tumor recurrence in high-grade serous ovarian cancer
- (2015) Mahrukh K. Ganapathi et al. INTERNATIONAL JOURNAL OF CANCER
- Inhibition of Survival Pathways MAPK and NF-kB Triggers Apoptosis in Pancreatic Ductal Adenocarcinoma Cells via Suppression of Autophagy
- (2015) Daniela Laura Papademetrio et al. Targeted Oncology
- Licochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathways
- (2015) Wenjin Hao et al. Scientific Reports
- Signal Transduction in Cancer
- (2015) R. Sever et al. Cold Spring Harbor Perspectives in Medicine
- Exploration of Aspergillus fumigatus Ras pathways for novel antifungal drug targets
- (2015) Qusai Al Abdallah et al. Frontiers in Microbiology
- Suppression of MAPK Signaling and Reversal of mTOR-Dependent MDR1-Associated Multidrug Resistance by 21α-Methylmelianodiol in Lung Cancer Cells
- (2015) Mark Borris Docdoc Aldonza et al. PLoS One
- NCRNA Combined Therapy as Future Treatment Option for Cancer
- (2014) Cornelia Braicu et al. CURRENT PHARMACEUTICAL DESIGN
- Sulforaphane Induces DNA Damage and Mitotic Abnormalities in Human Osteosarcoma MG-63 Cells: Correlation with Cell Cycle Arrest and Apoptosis
- (2014) José Miguel P. Ferreira de Oliveira et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Estrogen Receptor-α36 Is Involved in Pterostilbene-Induced Apoptosis and Anti-Proliferation in In Vitro and In Vivo Breast Cancer
- (2014) Chi Pan et al. PLoS One
- Acidic extracellular microenvironment and cancer
- (2013) Yasumasa Kato et al. Cancer Cell International
- p53siRNA therapy reduces cell proliferation, migration and induces apoptosis in triple negative breast cancer cells
- (2013) Cornelia Braicu et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Taxifolin Suppresses UV-Induced Skin Carcinogenesis by Targeting EGFR and PI3K
- (2012) N. Oi et al. Cancer Prevention Research
- The Natural Anticancer Compounds Rocaglamides Inhibit the Raf-MEK-ERK Pathway by Targeting Prohibitin 1 and 2
- (2012) Gernot Polier et al. CHEMISTRY & BIOLOGY
- Preferential inhibition of hepatocellular carcinoma by the flavonoid Baicalein through blocking MEK-ERK signaling
- (2012) RONG-RUI LIANG et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Effectiveness of sulforaphane as a radiosensitizer for murine osteosarcoma cells
- (2012) YASUSHI SAWAI et al. ONCOLOGY REPORTS
- Oncogenes in Cell Survival and Cell Death
- (2012) J. Shortt et al. Cold Spring Harbor Perspectives in Biology
- Extremophiles: radiation resistance microbial reserves and therapeutic implications
- (2011) O.V. Singh et al. JOURNAL OF APPLIED MICROBIOLOGY
- Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
- (2011) M. Cargnello et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- B-RAF Inhibitors: An Evolving Role in the Therapy of Malignant Melanoma
- (2010) Cynthia Shepherd et al. Current Oncology Reports
- Natural products and drug discovery. Can thousands of years of ancient medical knowledge lead us to new and powerful drug combinations in the fight against cancer and dementia?
- (2009) Hong-Fang Ji et al. EMBO REPORTS
- Vitisin A suppresses LPS-induced NO production by inhibiting ERK, p38, and NF-κB activation in RAW 264.7 cells
- (2009) Mi Jeong Sung et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Azaspirene, a fungal product, inhibits angiogenesis by blocking Raf-1 activation
- (2008) Yukihiro Asami et al. CANCER SCIENCE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search