期刊
JOURNAL OF APPLIED MICROBIOLOGY
卷 110, 期 4, 页码 851-861出版社
WILEY
DOI: 10.1111/j.1365-2672.2011.04971.x
关键词
anticancer; extremolytes; extremophiles; micro-organisms; therapeutics; ultraviolet radiation
资金
- University of Pittsburgh at Bradford
P>Micro-organisms with the ability to survive in extreme environmental conditions are known as 'extremophiles'. Currently, extremophiles have caused a sensation in the biotechnology/pharmaceutical industries with their novel compounds, known as 'extremolytes'. The potential applications of extremolytes are being investigated for human therapeutics including anticancer drugs, antioxidants, cell cycle-blocking agents, anticholesteric drugs, etc. It is hypothesized that the majority of ultraviolet radiation (UVR)-resistant micro-organisms can be used to develop anticancer drugs to prevent skin damage from UVR. The metabolites from UVR-resistant microbes are a great source of potential therapeutic applications in humans. This article aims to discuss the potentials of extremolytes along with their therapeutic implications of UVR extremophiles. The major challenges of therapeutic development using extremophiles are also discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据