Diastereodivergent Aldol‐Type Coupling of Alkoxyallenes with Pentafluorophenyl Esters Enabled by Synergistic Palladium/Chiral Lewis Base Catalysis

Organo/Transition-Metal Combined Catalysis Rejuvenates Both in Asymmetric Synthesis

(2022) Dian-Feng Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of α‐Aryl‐β2‐Amino‐esters via Cooperative Isothiourea and Brønsted Acid Catalysis

(2021) Andrew David Smith et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct and Enantioselective Aldol Reactions Catalyzed by Chiral Nickel(II) Complexes

(2021) Pedro Romea et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereodivergent Synthesis of Tertiary Fluoride-Tethered Allenes via Copper and Palladium Dual Catalysis

(2021) Shao-Qian Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Siloxy Esters as Traceless Activators of Carboxylic Acids: Boron‐Catalyzed Chemoselective Asymmetric Aldol Reaction

(2021) Taiki Fujita et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantio‐ and Diastereodivergent Synthesis of Spirocycles through Dual‐Metal‐Catalyzed [3+2] Annulation of 2‐Vinyloxiranes with Nucleophilic Dipoles

(2021) Youbin Peng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantio- and Diastereodivergent Construction of 1,3-Nonadjacent Stereocenters Bearing Axial and Central Chirality through Synergistic Pd/Cu Catalysis

(2021) Jiacheng Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synergistic Pd/Amine-Catalyzed Stereodivergent Hydroalkylation of 1,3-Dienes with Aldehydes: Reaction Development, Mechanism, and Stereochemical Origins

(2021) Hongfa Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Confinement-Controlled, Either syn- or anti-Selective Catalytic Asymmetric Mukaiyama Aldolizations of Propionaldehyde Enolsilanes

(2021) Tynchtyk Amatov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent Synthesis of Enantioenriched γ‐Butyrolactones Bearing Two Vicinal Stereocenters Enabled by Synergistic Copper and Iridium Catalysis

(2021) Lu Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Direct Aldol Addition of Aryl Ketones to α-Fluorinated Ketones

(2020) Connor J. Thomson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Syntheses of Strychnos and Chelidonium Alkaloids via Regio‐ and Stereocontrolled Cooperative Catalysis.

(2020) Thomas Neil Snaddon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereodivergent Pd/Cu Catalysis for the Dynamic Kinetic Asymmetric Transformation of Racemic Unsymmetrical 1,3-Disubstituted Allyl Acetates

(2020) Rui He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carbene‐Catalyzed Enantioselective Aldol Reaction: Post‐Aldol Stereochemistry Control and Formation of Quaternary Stereogenic Centers

(2020) Xing Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diastereodivergent Synthesis of β‐Amino Alcohols through Dual‐Metal‐Catalyzed Coupling of Alkoxyallenes with Aldimine Esters

(2020) Weiwei Zi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereodivergent Carbon–Carbon Bond Formation between Iminium and Enolate Intermediates by Synergistic Organocatalysis

(2020) Byungjun Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Catalytic Asymmetric Aldol Reaction of α-Alkoxyamides to α-Fluorinated Ketones

(2019) Roman Pluta et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereodivergent Synthesis through Catalytic Asymmetric Reversed Hydroboration

(2019) Tao-Tao Gao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

P-Chiral Phosphorus Ligands Based on a 2,3-Dihydrobenzo[d][1,3]oxaphosphole Motif for Asymmetric Catalysis

(2019) Guangqing Xu et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Regio- and Stereodivergent Synthesis of Homoallylic Amines via a One-Pot Cooperative Catalysis-based Allylic Alkylation/Hofmann Rearrangement Strategy

(2019) Colin Pearson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereodivergent Construction of Tertiary Fluorides in Vicinal Stereogenic Pairs by Allylic Substitution with Iridium and Copper Catalysts

(2019) Zhi-Tao He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent Coupling of 1,3-Dienes with Aldimine Esters Enabled by Synergistic Pd and Cu Catalysis

(2019) Qinglong Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Base-free Enantioselective C(1)-Ammonium Enolate Catalysis Exploiting Aryloxides: A Synthetic and Mechanistic Study

(2019) Calum McLaughlin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sequence-Dependent Stereodivergent Allylic Alkylation/Fluorination of Acyclic Ketones

(2019) Xi-Jia Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diastereodivergent synthesis of enantioenriched α,β-disubstituted γ-butyrolactones via cooperative N-heterocyclic carbene and Ir catalysis

(2019) Santanu Singha et al.   Nature Catalysis

Stereodivergent Synthesis of Tetrahydrofuroindoles through Pd-Catalyzed Asymmetric Dearomative Formal [3+2] Cycloaddition

(2018) Qiang Cheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective α-Benzylation of Acyclic Esters Using π-Extended Electrophiles.

(2018) Kevin Schwarz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Traversing Steric Limitations by Cooperative Lewis Base/Palladium Catalysis: An Enantioselective Synthesis of α-Branched Esters Using 2-Substituted Allyl Electrophiles

(2018) Kevin J. Schwarz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereodivergent Catalysis

(2018) Irina P. Beletskaya et al.   CHEMICAL REVIEWS

Catalytic enantioselective aldol reactions

(2018) Yasuhiro Yamashita et al.   CHEMICAL SOCIETY REVIEWS

Stereodivergent Synthesis of α,α-Disubstituted α-Amino Acids via Synergistic Cu/Ir Catalysis

(2018) Liang Wei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lewis Base/Copper Cooperatively Catalyzed Asymmetric α-Amination of Esters with Diaziridinone

(2018) Jin Song et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent Allylation of Azaaryl Acetamides and Acetates by Synergistic Iridium and Copper Catalysis

(2018) Xingyu Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ir/Cu Dual Catalysis: Enantio- and Diastereodivergent Access to α,α-Disubstituted α-Amino Acids Bearing Vicinal Stereocenters

(2018) Xiaohong Huo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent synthesis of 1,4-dicarbonyls by traceless charge–accelerated sulfonium rearrangement

(2018) Dainis Kaldre et al.   SCIENCE

Confined acids catalyze asymmetric single aldolizations of acetaldehyde enolates

(2018) Lucas Schreyer et al.   SCIENCE

Stereodivergent Coupling of Aldehydes and Alkynes via Synergistic Catalysis Using Rh and Jacobsen’s Amine

(2017) Faben A. Cruz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Enantioselective [2,3]-Rearrangements of Allylic Ammonium Ylides: A Mechanistic and Computational Study

(2017) Thomas H. West et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tandem Palladium and Isothiourea Relay Catalysis: Enantioselective Synthesis of α-Amino Acid Derivatives via Allylic Amination and [2,3]-Sigmatropic Rearrangement

(2017) Stéphanie S. M. Spoehrle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergence in Asymmetric Catalysis

(2017) Simon Krautwald et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd-Catalyzed Hydroamination of Alkoxyallenes with Azole Heterocycles: Examples and Mechanistic Proposal

(2017) Ivan Bernar et al.   ORGANIC LETTERS

Aryloxide-Promoted Catalyst Turnover in Lewis Base Organo­catalysis

(2017) Andrew Smith et al.   SYNTHESIS-STUTTGART

Cyclizations of Alkoxyallenes: Mechanisms, Intermediates, ­Products – A Personal Account on Solved and Unsolved Problems with Unique Allene Building Blocks

(2017) Hans-Ulrich Reissig et al.   SYNTHESIS-STUTTGART

From Palladium to Brønsted Acid Catalysis: Highly Enantioselective Regiodivergent Addition of Alkoxyallenes to Pyrazolones

(2016) Hui Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Combinations of Aminocatalysts and Metal Catalysts: A Powerful Cooperative Approach in Selective Organic Synthesis

(2016) Samson Afewerki et al.   CHEMICAL REVIEWS

Transition States of Vicinal Diamine-Catalyzed Aldol Reactions

(2016) Adam Simon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Ir/Zn Dual Catalysis for Enantio- and Diastereodivergent α-Allylation of α-Hydroxyketones

(2016) Xiaohong Huo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Uniting C1-Ammonium Enolates and Transition Metal Electrophiles via Cooperative Catalysis: The Direct Asymmetric α-Allylation of Aryl Acetic Acid Esters

(2016) Kevin J. Schwarz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent Allylic Substitutions with Aryl Acetic Acid Esters by Synergistic Iridium and Lewis Base Catalysis

(2016) Xingyu Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-catalysed enantioselective stereodivergent synthesis of amino alcohols

(2016) Shi-Liang Shi et al.   NATURE

Stereodivergent Dual Catalytic α-Allylation of Protected α-Amino- and α-Hydroxyacetaldehydes

(2015) Tobias Sandmeier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Organocatalysis Combined with Metal Catalysis: Concept, Proof of Concept, and Beyond

(2014) Dian-Feng Chen et al.   ACCOUNTS OF CHEMICAL RESEARCH

Alkoxyallenes as building blocks for organic synthesis

(2014) Reinhold Zimmer et al.   CHEMICAL SOCIETY REVIEWS

An Isothiourea-Catalyzed Asymmetric [2,3]-Rearrangement of Allylic Ammonium Ylides

(2014) Thomas H. West et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd-Catalyzed Asymmetric Intermolecular Hydroalkoxylation of Allene: An Entry to Cyclic Acetals with Activating Group-Free and Flexible Anomeric Control

(2014) Wontaeck Lim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent α-Allylation of Linear Aldehydes with Dual Iridium and Amine Catalysis

(2014) Simon Krautwald et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dual Catalysis Becomes Diastereodivergent

(2013) Maria Teresa Oliveira et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A New Twist on Cooperative Catalysis

(2013) C. S. Schindler et al.   SCIENCE

Enantio- and Diastereodivergent Dual Catalysis:  -Allylation of Branched Aldehydes

(2013) S. Krautwald et al.   SCIENCE

Synthetic Strategy for Cyclic Amines: A Stereodefined Cyclic N,O-Acetal as a Stereocontrol and Diversity-Generating Element

(2012) Haejin Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereodefined N,O-Acetals: Pd-Catalyzed Synthesis from Homopropargylic Amines and Utility in the Flexible Synthesis of 2,6-Substituted Piperidines

(2012) Haejin Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Diastereodivergent Deracemization

(2011) Marco Luparia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Palladium Catalyzed Asymmetric Addition of Oxindoles and Allenes: An Atom-Economical Versatile Method for the Construction of Chiral Indole Alkaloids

(2011) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The direct catalytic asymmetric aldol reaction

(2010) Barry M. Trost et al.   CHEMICAL SOCIETY REVIEWS

Copper Catalyzed Asymmetric Propargylation of Aldehydes

(2010) Daniel R. Fandrick et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transition State Models for Probing Stereoinduction in Evans Chiral Auxiliary-Based Asymmetric Aldol Reactions

(2010) C. B. Shinisha et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Heterocyclic Carbene-Catalyzed Enantioselective Mannich Reactions with α-Aryloxyacetaldehydes

(2009) Yasufumi Kawanaka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Novel, Tunable, and Efficient Chiral Bisdihydrobenzooxaphosphole Ligands for Asymmetric Hydrogenation

(2009) Wenjun Tang et al.   ORGANIC LETTERS

Sugars, Alkaloids, and Heteroaromatics: Exploring Heterocyclic Chemistry with Alkoxyallenes†

(2008) Malte Brasholz et al.   ACCOUNTS OF CHEMICAL RESEARCH