Organo/Transition-Metal Combined Catalysis Rejuvenates Both in Asymmetric Synthesis

Catalytic Diastereo‐ and Enantioconvergent Synthesis of Vicinal Diamines from Diols through Borrowing Hydrogen

(2021) Hui‐Jie Pan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic Pd/Amine-Catalyzed Stereodivergent Hydroalkylation of 1,3-Dienes with Aldehydes: Reaction Development, Mechanism, and Stereochemical Origins

(2021) Hongfa Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synergistic catalysis in an artificial enzyme by simultaneous action of two abiological catalytic sites

(2020) Zhi Zhou et al.   Nature Catalysis

Palladium-Catalyzed Asymmetric Allylic C–H Functionalization: Mechanism, Stereo- and Regioselectivities, and Synthetic Applications

(2020) Pu-Sheng Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Exploiting attractive non-covalent interactions for the enantioselective catalysis of reactions involving radical intermediates

(2020) Rupert S. J. Proctor et al.   Nature Chemistry

Asymmetric Allylic Alkylation with Deconjugated Carbonyl Compounds: Direct Vinylogous Umpolung Strategy

(2019) Guang-Yao Ran et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene/Copper Cooperative Catalysis for the Asymmetric Synthesis of Spirooxindoles

(2019) Zi-Jing Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly enantioselective carbene insertion into N–H bonds of aliphatic amines

(2019) Mao-Lin Li et al.   SCIENCE

Recent Progress in Asymmetric Relay Catalysis of Metal Complex with Chiral Phosphoric Acid

(2019) Pu-Sheng Wang et al.   Topics in Current Chemistry

Diastereodivergent synthesis of enantioenriched α,β-disubstituted γ-butyrolactones via cooperative N-heterocyclic carbene and Ir catalysis

(2019) Santanu Singha et al.   Nature Catalysis

Enantioselective Desymmetrization of Cyclobutanones Enabled by Synergistic Palladium/Enamine Catalysis

(2018) Meng Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective α-Benzylation of Acyclic Esters Using π-Extended Electrophiles.

(2018) Kevin Schwarz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective [5 + 2] Annulations through Cooperative N-Heterocyclic Carbene (NHC) Organocatalysis and Palladium Catalysis

(2018) Santanu Singha et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Predicting reaction performance in C–N cross-coupling using machine learning

(2018) Derek T. Ahneman et al.   SCIENCE

Mechanism and reactivity of catalytic propargylic substitution reactions via metal–allenylidene intermediates: a theoretical perspective

(2018) Ken Sakata et al.   Catalysis Science & Technology

α-Quaternary Chiral Aldehydes from Styrenes, Allylic Alcohols, and Syngas via Multi-catalyst Relay Catalysis

(2018) Jing Meng et al.   Chem

Stereodivergent Coupling of Aldehydes and Alkynes via Synergistic Catalysis Using Rh and Jacobsen’s Amine

(2017) Faben A. Cruz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Terminal Addition to Allenes by Dual Chiral Primary Amine/Palladium Catalysis

(2017) Han Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanistic Studies on a Cooperative NHC Organocatalysis/Palladium Catalysis System: Uncovering Significant Lessons for Mixed Chiral Pd(NHC)(PR3) Catalyst Design

(2017) Chang Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Catalysis with CO2 : The Direct α-Allylation of Ketones

(2016) Gabriele Pupo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium/l-Proline-Catalyzed Enantioselective α-Arylative Desymmetrization of Cyclohexanones

(2016) Ren-Rong Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cooperative N-Heterocyclic Carbene/Palladium-Catalyzed Enantioselective Umpolung Annulations

(2016) Chang Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Enantioselective Allylic C–H Alkylation of Terminal Olefins with Pyrazol-5-ones Enabled by Cooperative Catalysis of Palladium Complex and Brønsted Acid

(2016) Hua-Chen Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Uniting C1-Ammonium Enolates and Transition Metal Electrophiles via Cooperative Catalysis: The Direct Asymmetric α-Allylation of Aryl Acetic Acid Esters

(2016) Kevin J. Schwarz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent Allylic Substitutions with Aryl Acetic Acid Esters by Synergistic Iridium and Lewis Base Catalysis

(2016) Xingyu Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric [4 + 1] Annulation of Sulfur Ylides with Copper–Allenylidene Intermediates

(2016) Qiang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Axial Tri-tert-butylphosphane Coordination to Rh2(OAc)4: Synthesis, Structure, and Catalytic Studies

(2016) Jiantao Tan et al.   ORGANOMETALLICS

Chiral Primary Amine/Palladium Dual Catalysis for Asymmetric Allylic Alkylation of β-Ketocarbonyl Compounds with Allylic Alcohols

(2015) Han Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereodivergent Dual Catalytic α-Allylation of Protected α-Amino- and α-Hydroxyacetaldehydes

(2015) Tobias Sandmeier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Origin of Stereodivergence in Cooperative Asymmetric Catalysis with Simultaneous Involvement of Two Chiral Catalysts

(2015) Bangaru Bhaskararao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dynamic Kinetic Asymmetric Amination of Alcohols: From A Mixture of Four Isomers to Diastereo- and Enantiopure α-Branched Amines

(2015) Zi-Qiang Rong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic asymmetric umpolung reactions of imines

(2015) Yongwei Wu et al.   NATURE

Asymmetric Organocatalysis Combined with Metal Catalysis: Concept, Proof of Concept, and Beyond

(2014) Dian-Feng Chen et al.   ACCOUNTS OF CHEMICAL RESEARCH

CH Functionalization/Asymmetric Michael Addition Cascade Enabled by Relay Catalysis: Metal Carbenoid Used for CC Bond Formation

(2014) Dian-Feng Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cooperative Catalysis by Palladium and a Chiral Phosphoric Acid: Enantioselective Amination of Racemic Allylic Alcohols

(2014) Debasis Banerjee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structure and Reactivity of Late Transition Metal η3-Benzyl Complexes

(2014) Barry M. Trost et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Counteranion Strategy for Asymmetric Oxidative C(sp3)H/C(sp3)H Coupling: Enantioselective α-Allylation of Aldehydes with Terminal Alkenes

(2014) Pu-Sheng Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereodivergent Total Synthesis of Δ9-Tetrahydrocannabinols

(2014) Michael A. Schafroth et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Lewis base functionalisation of carboxylic acids, esters and anhydrides via C1-ammonium or azolium enolates

(2014) Louis C. Morrill et al.   CHEMICAL SOCIETY REVIEWS

Stereodivergent α-Allylation of Linear Aldehydes with Dual Iridium and Amine Catalysis

(2014) Simon Krautwald et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Importance of Ligand Exchanges in Pd(II)-Brønsted Acid Cooperative Catalytic Approach to Spirocyclic Rings

(2014) Garima Jindal et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Novel Multicomponent Reactions via Trapping of Protic Onium Ylides with Electrophiles

(2013) Xin Guo et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cooperative Catalysis through Noncovalent Interactions

(2013) Weijun Tang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Iron/Amine-Catalyzed Cascade Process for the Enantioselective Functionalization of Allylic Alcohols

(2013) Adrien Quintard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Amination of Alcohols by the Use of Borrowing Hydrogen Methodology: Cooperative Catalysis by Iridium and a Chiral Phosphoric Acid

(2013) Yao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd-Catalyzed Asymmetric Allylic Alkylation of Pyrazol-5-ones with Allylic Alcohols: The Role of the Chiral Phosphoric Acid in C–O Bond Cleavage and Stereocontrol

(2013) Zhong-Lin Tao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Cascade Annulation Based on Enantioselective Oxa-Diels–Alder Cycloaddition of in Situ Generated Isochromenyliums by Cooperative Binary Catalysis of Pd(OAc)2 and (S)-Trip

(2013) Shu-Yan Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium/Chiral Urea Relay Catalysis Enables an Enantioselective Semipinacol Rearrangement/Michael Addition Cascade

(2013) Dian-Feng Chen et al.   ORGANIC LETTERS

Enantio- and Diastereodivergent Dual Catalysis:  -Allylation of Branched Aldehydes

(2013) S. Krautwald et al.   SCIENCE

New Progress and Prospects of Transition Metal-Catalyzed Asymmetric Hydrogenation

(2012) Jianhua Xie et al.   ACTA CHIMICA SINICA

Combining transition metal catalysis and organocatalysis – an update

(2012) Zhenting Du et al.   CHEMICAL SOCIETY REVIEWS

Direct Regiospecific and Highly Enantioselective Intermolecular α-Allylic Alkylation of Aldehydes by a Combination of Transition-Metal and Chiral Amine Catalysts

(2012) Samson Afewerki et al.   CHEMISTRY-A EUROPEAN JOURNAL

Pd(II)/Brønsted Acid Catalyzed Enantioselective Allylic C–H Activation for the Synthesis of Spirocyclic Rings

(2012) Zhuo Chai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective α-Vinylation of Aldehydes via the Synergistic Combination of Copper and Amine Catalysis

(2012) Eduardas Skucas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Benzylic Phosphates as Electrophiles in the Palladium-Catalyzed Asymmetric Benzylation of Azlactones

(2012) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dual Amine and Palladium Catalysis in Diastereo- and Enantioselective Allene Carbocyclization Reactions

(2012) Meiling Li et al.   ORGANIC LETTERS

Cooperative Catalytic Reactions Using Organocatalysts and Transition Metal Catalysts: Propargylic Allylation of Propargylic Alcohols with α,β-Unsaturated Aldehydes

(2012) Masahiro Ikeda et al.   ORGANOMETALLICS

Synergistic catalysis: A powerful synthetic strategy for new reaction development

(2012) Anna E. Allen et al.   Chemical Science

Asymmetric NH Insertion Reaction Cooperatively Catalyzed by Rhodium and Chiral Spiro Phosphoric Acids

(2011) Bin Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Asymmetric α-Allylation of Aldehydes with Simple Allylic Alcohols Enabled by the Concerted Action of Three Different Catalysts

(2011) Gaoxi Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cooperative Transition-Metal and Chiral Brønsted Acid Catalysis: Enantioselective Hydrogenation of Imines To Form Amines

(2011) Shaolin Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Contemporaneous Dual Catalysis by Coupling Highly Transient Nucleophilic and Electrophilic Intermediates Generated in Situ

(2011) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biomimetic Asymmetric Hydrogenation: In Situ Regenerable Hantzsch Esters for Asymmetric Hydrogenation of Benzoxazinones

(2011) Qing-An Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective α-Arylation of Aldehydes via the Productive Merger of Iodonium Salts and Organocatalysis

(2011) Anna E. Allen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Convergent Asymmetric Disproportionation Reactions: Metal/Brønsted Acid Relay Catalysis for Enantioselective Reduction of Quinoxalines

(2011) Qing-An Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cooperative Catalytic Reactions Using Organocatalysts and Transition Metal Catalysts: Enantioselective Propargylic Alkylation of Propargylic Esters with Aldehydes

(2011) Akiko Yoshida et al.   ORGANIC LETTERS

Cooperative Lewis acid/N-heterocyclic carbene catalysis

(2011) Daniel T. Cohen et al.   Chemical Science

Cooperative Catalytic Reactions Using Organocatalysts and Transition-Metal Catalysts: Enantioselective Propargylic Alkylation of Propargylic Alcohols with Aldehydes

(2010) Masahiro Ikeda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Combining transition metal catalysis and organocatalysis: a broad new concept for catalysis

(2009) Zhihui Shao et al.   CHEMICAL SOCIETY REVIEWS

Chiral Counteranion-Aided Asymmetric Hydrogenation of Acyclic Imines

(2008) Chaoqun Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cooperative Catalysis with Chiral Brønsted Acid-Rh2(OAc)4: Highly Enantioselective Three-Component Reactions of Diazo Compounds with Alcohols and Imines

(2008) Wenhao Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Merging Photoredox Catalysis with Organocatalysis: The Direct Asymmetric Alkylation of Aldehydes

(2008) D. A. Nicewicz et al.   SCIENCE