Acacetin Prevents Bone Loss by Disrupting Osteoclast Formation and Promoting Type H Vessel Formation in Ovariectomy-Induced Osteoporosis

Acacetin Ameliorates Experimental Colitis in Mice via Inhibiting Macrophage Inflammatory Response and Regulating the Composition of Gut Microbiota

(2021) Junyu Ren et al.   Frontiers in Physiology

Icariin stimulates osteogenesis and suppresses adipogenesis of human bone mesenchymal stem cells via miR-23a-mediated activation of the Wnt/β-catenin signaling pathway

(2021) Yingxing Xu et al.   PHYTOMEDICINE

Celastrol Attenuates RANKL-Induced Osteoclastogenesis in vitro and Reduces Titanium Particle-Induced Osteolysis and Ovariectomy-Induced Bone Loss in vivo

(2021) Qiang Xu et al.   Frontiers in Pharmacology

Nuciferine prevents bone loss by disrupting multinucleated osteoclast formation and promoting type H vessel formation

(2020) Chengchao Song et al.   FASEB JOURNAL

Arctiin abrogates osteoclastogenesis and bone resorption via suppressing RANKL-induced ROS and NFATc1 activation

(2020) Chen Delong et al.   PHARMACOLOGICAL RESEARCH

Positive Effect of Gushukang on Type-H Vessel and Bone Formation

(2020) Wantao Li et al.   Frontiers in Cell and Developmental Biology

Acacetin improves endothelial dysfunction and aortic fibrosis in insulin-resistant SHR rats by estrogen receptors

(2020) Yaxin Wei et al.   MOLECULAR BIOLOGY REPORTS

Potential Advantages of Bioactive Compounds Extracted From Traditional Chinese Medicine to Inhibit Bone Destructions in Rheumatoid Arthritis

(2020) Yingjie Shi et al.   Frontiers in Pharmacology

Linarin and its aglycone acacetin abrogate actin ring formation and focal contact to bone matrix of bone-resorbing osteoclasts through inhibition of αvβ3 integrin and core-linked CD44

(2020) Soo-Il Kim et al.   PHYTOMEDICINE

An Overview of the NF-kB mechanism of pathophysiology in rheumatoid arthritis, investigation of the NF-kB ligand RANKL and related nutritional interventions

(2020) Desislava (Daisy) Ilchovska et al.   AUTOIMMUNITY REVIEWS

Flavonoids in Bone Erosive Diseases: Perspectives in Osteoporosis Treatment

(2020) Daniele Bellavia et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The Cost of Osteoporosis, Osteopenia, and Associated Fractures in Australia in 2017

(2019) Gemma Tatangelo et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The association between CD31hiEmcnhi endothelial cells and bone mineral density in Chinese women

(2019) Yong Zhu et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Medical Treatment for Osteoporosis: From Molecular to Clinical Opinions

(2019) Li-Ru Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Macrophage-lineage TRAP+ cells recruit periosteum-derived cells for periosteal osteogenesis and regeneration

(2019) Bo Gao et al.   JOURNAL OF CLINICAL INVESTIGATION

Microtubule actin crosslinking factor 1 (MACF1) knockdown inhibits RANKL-induced osteoclastogenesis via Akt/GSK3β/NFATc1 signalling pathway

(2019) Xiao Lin et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Effect of Abaloparatide Versus Alendronate on Fracture Risk Reduction in Postmenopausal Women With Osteoporosis

(2019) Benjamin Z Leder et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Catalpol suppresses osteoclastogenesis and attenuates osteoclast-derived bone resorption by modulating PTEN activity

(2019) Jiahong Meng et al.   BIOCHEMICAL PHARMACOLOGY

Preservation of type H vessels and osteoblasts by enhanced preosteoclast platelet-derived growth factor type BB attenuates glucocorticoid-induced osteoporosis in growing mice

(2018) Ping Yang et al.   BONE

Recent advances in osteoclast biology

(2018) Takehito Ono et al.   HISTOCHEMISTRY AND CELL BIOLOGY

18β-Glycyrrhetinic Acid Inhibits Osteoclastogenesis In Vivo and In Vitro by Blocking RANKL-Mediated RANK–TRAF6 Interactions and NF-κB and MAPK Signaling Pathways

(2018) Xiao Chen et al.   Frontiers in Pharmacology

α-1 Antitrypsin Inhibits RANKL-induced Osteoclast Formation and Functions

(2017) Mohammad Ahsanul Akbar et al.   MOLECULAR MEDICINE

Human type H vessels are a sensitive biomarker of bone mass

(2017) Liang Wang et al.   Cell Death & Disease

Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway

(2017) Mengrui Wu et al.   Nature Communications

The effect of raloxifene on bone marrow adipose tissue and bone turnover in postmenopausal women with osteoporosis

(2017) Kerensa M. Beekman et al.   BONE

Preparative Purification of Bioactive Compounds fromFlos Chrysanthemi Indiciand Evaluation of Its Antiosteoporosis Effect

(2016) Jia Li et al.   Evidence-based Complementary and Alternative Medicine

Inactivation of Regulatory-associated Protein of mTOR (Raptor)/Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling in Osteoclasts Increases Bone Mass by Inhibiting Osteoclast Differentiation in Mice

(2016) Qinggang Dai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blood flow controls bone vascular function and osteogenesis

(2016) Saravana K. Ramasamy et al.   Nature Communications

Gastrodin: An ancient Chinese herbal medicine as a source for anti-osteoporosis agents via reducing reactive oxygen species

(2015) Qiang Huang et al.   BONE

Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone

(2014) Anjali P. Kusumbe et al.   NATURE

PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis

(2014) Hui Xie et al.   NATURE MEDICINE

Association between dietary intake of flavonoid and bone mineral density in middle aged and elderly Chinese women and men

(2014) Z.-q. Zhang et al.   OSTEOPOROSIS INTERNATIONAL

Acacetin Inhibits In Vitro and In Vivo Angiogenesis and Downregulates Stat Signaling and VEGF Expression

(2013) T. A. Bhat et al.   Cancer Prevention Research

The P110 subunit of PI3-K is a therapeutic target of acacetin in skin cancer

(2013) Sung Keun Jung et al.   CARCINOGENESIS

Akt Induces Osteoclast Differentiation through Regulating the GSK3 /NFATc1 Signaling Cascade

(2011) J. B. Moon et al.   JOURNAL OF IMMUNOLOGY

Associations between dietary flavonoid intakes and bone health in a scottish population

(2010) Antonia C Hardcastle et al.   JOURNAL OF BONE AND MINERAL RESEARCH