Blood flow controls bone vascular function and osteogenesis

α1B-Adrenoceptor signalling regulates bone formation through the up-regulation of CCAAT/enhancer-binding protein δ expression in osteoblasts

(2016) Kenjiro Tanaka et al.   BRITISH JOURNAL OF PHARMACOLOGY

Age-dependent modulation of vascular niches for haematopoietic stem cells

(2016) Anjali P. Kusumbe et al.   NATURE

Anabolic actions of Notch on mature bone

(2016) Peng Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Making sense of hematopoietic stem cell niches

(2015) P. E. Boulais et al.   BLOOD

Bone development

(2015) Agnes D. Berendsen et al.   BONE

Bringing new life to damaged bone: The importance of angiogenesis in bone repair and regeneration

(2015) Steve Stegen et al.   BONE

A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturation

(2015) E. Kozhemyakina et al.   DEVELOPMENT

The molecular regulation of arteriovenous specification and maintenance

(2015) Jason E. Fish et al.   DEVELOPMENTAL DYNAMICS

Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal

(2015) Melih Acar et al.   NATURE

Notch1 Is Pan-Endothelial at the Onset of Flow and Regulated by Flow

(2015) Espen D. Jahnsen et al.   PLoS One

Signaling Pathways in the Specification of Arteries and Veins

(2014) Monica Corada et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The bone marrow niche for haematopoietic stem cells

(2014) Sean J. Morrison et al.   NATURE

Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone

(2014) Anjali P. Kusumbe et al.   NATURE

Endothelial Notch activity promotes angiogenesis and osteogenesis in bone

(2014) Saravana K. Ramasamy et al.   NATURE

PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis

(2014) Hui Xie et al.   NATURE MEDICINE

Constitutively active Notch4 receptor elicits brain arteriovenous malformations through enlargement of capillary-like vessels

(2014) Patrick A. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Skeletal Blood Flow in Bone Repair and Maintenance

(2014) Ryan E. Tomlinson et al.   Bone Research

Notch-Dependent Regulation of the Ischemic Vasodilatory Response—Brief Report

(2013) Alex C.Y. Chang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Blood flow suppresses vascular Notch signalling via dll4 and is required for angiogenesis in response to hypoxic signalling

(2013) Oliver Watson et al.   CARDIOVASCULAR RESEARCH

Fluid Shear Stress on Endothelial Cells Modulates Mechanical Tension across VE-Cadherin and PECAM-1

(2013) Daniel E. Conway et al.   CURRENT BIOLOGY

Arteriolar niches maintain haematopoietic stem cell quiescence

(2013) Yuya Kunisaki et al.   NATURE

Arteriovenous Malformations and Other Vascular Malformation Syndromes

(2013) K. J. Whitehead et al.   Cold Spring Harbor Perspectives in Medicine

Mechanosensation and transduction in osteocytes

(2012) Jenneke Klein-Nulend et al.   BONE

Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF–VEGFR2 signalling

(2012) Rui Benedito et al.   NATURE

The Dll4/Notch pathway controls postangiogenic blood vessel remodeling and regression by modulating vasoconstriction and blood flow

(2011) I. B. Lobov et al.   BLOOD

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

(2010) Hugo J. Snippert et al.   CELL

Osteoblast Precursors, but Not Mature Osteoblasts, Move into Developing and Fractured Bones along with Invading Blood Vessels

(2010) Christa Maes et al.   DEVELOPMENTAL CELL

MicroRNA-mediated integration of haemodynamics and Vegf signalling during angiogenesis

(2010) Stefania Nicoli et al.   NATURE

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

(2010) Yingdi Wang et al.   NATURE

Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun

(2010) Joerg D Hoeck et al.   NATURE NEUROSCIENCE

The forming limb skeleton serves as a signaling center for limb vasculature patterning via regulation of Vegf

(2009) I. Eshkar-Oren et al.   DEVELOPMENT

Angiogenesis: A Team Effort Coordinated by Notch

(2009) L.-K. Phng et al.   DEVELOPMENTAL CELL

Increased skeletal VEGF enhances β-catenin activity and results in excessively ossified bones

(2009) Christa Maes et al.   EMBO JOURNAL

Bisphosphonates: Mechanism of Action and Role in Clinical Practice

(2009) Matthew T. Drake et al.   MAYO CLINIC PROCEEDINGS

Measuring bone blood supply in mice using fluorescent microspheres

(2009) Maria A Serrat   Nature Protocols

Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hind-limb ischemia

(2009) Anne Limbourg et al.   Nature Protocols

Branching morphogenesis and antiangiogenesis candidates: tip cells lead the way

(2009) Peter Carmeliet et al.   Nature Reviews Clinical Oncology

Fluid shear stress induces arterial differentiation of endothelial progenitor cells

(2008) Syotaro Obi et al.   JOURNAL OF APPLIED PHYSIOLOGY

Dimorphic effects of Notch signaling in bone homeostasis

(2008) Feyza Engin et al.   NATURE MEDICINE

Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

(2008) Matthew J Hilton et al.   NATURE MEDICINE

Activation of the hypoxia-inducible factor-1  pathway accelerates bone regeneration

(2008) C. Wan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA