Therapeutically viable generation of neurons with antisense oligonucleotide suppression of PTB

Silencing of microRNA-135b inhibits invasion, migration, and stemness of CD24+CD44+ pancreatic cancer stem cells through JADE-1-dependent AKT/mTOR pathway

(2020) Jingyang Zhou et al.   Cancer Cell International

Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice

(2020) Haibo Zhou et al.   CELL

Antisense oligonucleotides for neurodegeneration

(2020) Blair R. Leavitt et al.   SCIENCE

Reversing a model of Parkinson’s disease with in situ converted nigral neurons

(2020) Hao Qian et al.   NATURE

Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS

(2020) Timothy Miller et al.   NEW ENGLAND JOURNAL OF MEDICINE

Steps towards standardized quantification of adult neurogenesis

(2020) Xinyu Zhao et al.   Nature Communications

The atlas of RNase H antisense oligonucleotide distribution and activity in the CNS of rodents and non-human primates following central administration

(2020) Paymaan Jafar-nejad et al.   NUCLEIC ACIDS RESEARCH

Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons

(2019) Simon T. Schafer et al.   NATURE NEUROSCIENCE

Antisense Oligonucleotide Therapies for Neurodegenerative Diseases

(2019) C. Frank Bennett et al.   Annual Review of Neuroscience

Cell-autonomous and non-cell autonomous effects of neuronal BIN1 loss in vivo

(2019) Kathleen M. McAvoy et al.   PLoS One

Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development

(2019) Cleber A. Trujillo et al.   Cell Stem Cell

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

(2018) Shawn F. Sorrells et al.   NATURE

Preparation of Acute Brain Slices Using an Optimized N-Methyl-D-glucamine Protective Recovery Method

(2018) Jonathan T. Ting et al.   Jove-Journal of Visualized Experiments

New approaches for brain repair—from rescue to reprogramming

(2018) Roger A. Barker et al.   NATURE

Targeting PIM Kinases Affects Maintenance of CD133 Tumor Cell Population in Hepatoblastoma

(2018) Laura L. Stafman et al.   Translational Oncology

Viral Vector Reprogramming of Adult Resident Striatal Oligodendrocytes into Functional Neurons

(2017) Marc S. Weinberg et al.   MOLECULAR THERAPY

The use of brain organoids to investigate neural development and disease

(2017) Elizabeth Di Lullo et al.   NATURE REVIEWS NEUROSCIENCE

Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy

(2017) Richard S. Finkel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Astrocyte deletion of Bmal1 alters daily locomotor activity and cognitive functions via GABA signalling

(2017) Olga Barca-Mayo et al.   Nature Communications

Letter to the editor: Accurate cell capacitance determination from a single voltage step: a reminder to avoid unnecessary pitfalls

(2016) Dieter Platzer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells

(2016) Gioele La Manno et al.   CELL

Decreased expression of class III β-tubulin is associated with unfavourable prognosis in patients with malignant melanoma

(2016) Akira Shimizu et al.   MELANOMA RESEARCH

Evaluating cell reprogramming, differentiation and conversion technologies in neuroscience

(2016) Jerome Mertens et al.   NATURE REVIEWS NEUROSCIENCE

Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs

(2016) Jie Jiang et al.   NEURON

Adult Mammalian Neural Stem Cells and Neurogenesis: Five Decades Later

(2015) Allison M. Bond et al.   Cell Stem Cell

Loss of galectin-3 decreases the number of immune cells in the subventricular zone and restores proliferation in a viral model of multiple sclerosis

(2015) Rachel E. James et al.   GLIA

Systemic attenuation of the TGF-β pathway by a single drug simultaneously rejuvenates hippocampal neurogenesis and myogenesis in the same old mammal

(2015) Hanadie Yousef et al.   Oncotarget

Astrocyte Depletion Impairs Redox Homeostasis and Triggers Neuronal Loss in the Adult CNS

(2015) Bettina Schreiner et al.   Cell Reports

Enrichment rescues contextual discrimination deficit associated with immediate shock

(2014) Gregory D. Clemenson et al.   HIPPOCAMPUS

Epigenetics of cellular reprogramming

(2013) Raga Krishnakumar et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study

(2013) Timothy M Miller et al.   LANCET NEUROLOGY

Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin Synthesis

(2012) Holly B. Kordasiewicz et al.   NEURON

Novel object exploration in mice: Not all objects are created equal

(2011) Charles J. Heyser et al.   BEHAVIOURAL PROCESSES

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions

(2011) Guo-li Ming et al.   NEURON

Direct conversion of fibroblasts to functional neurons by defined factors

(2010) Thomas Vierbuchen et al.   NATURE

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

(2010) Wei Deng et al.   NATURE REVIEWS NEUROSCIENCE

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Mechanisms and Functional Implications of Adult Neurogenesis

(2008) Chunmei Zhao et al.   CELL

Newborn granule cells in the ageing dentate gyrus

(2008) Nicolás A. Morgenstern et al.   JOURNAL OF PHYSIOLOGY-LONDON

Neurons born in the adult dentate gyrus form functional synapses with target cells

(2008) Nicolas Toni et al.   NATURE NEUROSCIENCE