Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model

Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells

(2016) Gioele La Manno et al.   CELL

Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming

(2016) Sergio Gascón et al.   Cell Stem Cell

Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brain

(2016) Zachary Freyberg et al.   Nature Communications

The 6-OHDA mouse model of Parkinson's disease – Terminal striatal lesions provide a superior measure of neuronal loss and replacement than median forebrain bundle lesions

(2015) V. Bagga et al.   BEHAVIOURAL BRAIN RESEARCH

How to make a midbrain dopaminergic neuron

(2015) E. Arenas et al.   DEVELOPMENT

Transdifferentiation via transcription factors or microRNAs: Current status and perspective

(2015) Huan Wang et al.   DIFFERENTIATION

Axial disability and deep brain stimulation in patients with Parkinson disease

(2015) Alfonso Fasano et al.   Nature Reviews Neurology

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

(2015) A. Zeisel et al.   SCIENCE

In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry

(2015) Olof Torper et al.   Cell Reports

In vivo conversion of astrocytes to neurons in the injured adult spinal cord

(2014) Zhida Su et al.   Nature Communications

A mouse model of non-motor symptoms in Parkinson's disease: focus on pharmacological interventions targeting affective dysfunctions

(2014) Alessandra Bonito-Oliva et al.   Frontiers in Behavioral Neuroscience

Sox2-Mediated Conversion of NG2 Glia into Induced Neurons in the Injured Adult Cerebral Cortex

(2014) Christophe Heinrich et al.   Stem Cell Reports

New Fluorescent Substrate Enables Quantitative and High-Throughput Examination of Vesicular Monoamine Transporter 2 (VMAT2)

(2013) Gang Hu et al.   ACS Chemical Biology

In Vivo Direct Reprogramming of Reactive Glial Cells into Functional Neurons after Brain Injury and in an Alzheimer’s Disease Model

(2013) Ziyuan Guo et al.   Cell Stem Cell

Erratum: Phosphorylation-enabled binding of SGO1–PP2A to cohesin protects sororin and centromeric cohesion during mitosis

(2013) Hong Liu et al.   NATURE CELL BIOLOGY

Leveling Waddington: the emergence of direct programming and the loss of cell fate hierarchies

(2013) Julia Ladewig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Brief demethylation step allows the conversion of adult human skin fibroblasts into insulin-secreting cells

(2013) G. Pennarossa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of induced neurons via direct conversion in vivo

(2013) O. Torper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parkinson's Disease and Parkinsonism: Neuropathology

(2013) D. W. Dickson   Cold Spring Harbor Perspectives in Medicine

Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells

(2011) Xinjian Liu et al.   CELL RESEARCH

Functional Integration of Dopaminergic Neurons Directly Converted from Mouse Fibroblasts

(2011) Jongpil Kim et al.   Cell Stem Cell

Postnatal development of tyrosine hydroxylase mRNA-expressing neurons in mouse neostriatum

(2011) Masao Masuda et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Direct generation of functional dopaminergic neurons from mouse and human fibroblasts

(2011) Massimiliano Caiazzo et al.   NATURE

Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease

(2011) Sonja Kriks et al.   NATURE

Induction of human neuronal cells by defined transcription factors

(2011) Zhiping P. Pang et al.   NATURE

Generation of subtype-specific neurons from postnatal astroglia of the mouse cerebral cortex

(2011) Christophe Heinrich et al.   Nature Protocols

Efficient Conversion of Astrocytes to Functional Midbrain Dopaminergic Neurons Using a Single Polycistronic Vector

(2011) Russell C. Addis et al.   PLoS One

Direct conversion of human fibroblasts to dopaminergic neurons

(2011) U. Pfisterer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Towards stem cell replacement therapies for Parkinson’s disease

(2010) Ernest Arenas   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells

(2010) Miguel Angel Esteban et al.   Cell Stem Cell

Direct conversion of fibroblasts to functional neurons by defined factors

(2010) Thomas Vierbuchen et al.   NATURE

Vitamin C Promotes Widespread Yet Specific DNA Demethylation of the Epigenome in Human Embryonic Stem Cells

(2010) Tung-Liang Chung et al.   STEM CELLS

Wnt1-cre-mediated Conditional Loss of Dicer Results in Malformation of the Midbrain and Cerebellum and Failure of Neural Crest and Dopaminergic Differentiation in Mice

(2010) Tianwen Huang et al.   Journal of Molecular Cell Biology

Directing Astroglia from the Cerebral Cortex into Subtype Specific Functional Neurons

(2010) Christophe Heinrich et al.   PLOS BIOLOGY

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

Tests to assess motor phenotype in mice: a user's guide

(2009) Simon P. Brooks et al.   NATURE REVIEWS NEUROSCIENCE

Sequential Expression of Pluripotency Markers during Direct Reprogramming of Mouse Somatic Cells

(2008) Tobias Brambrink et al.   Cell Stem Cell

Tyrosine hydroxylase cells appearing in the mouse striatum after dopamine denervation are likely to be projection neurones regulated by l-DOPA

(2008) Sanja Darmopil et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

(2008) Danwei Huangfu et al.   NATURE BIOTECHNOLOGY